Jay L Koyner

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. pmc Assessment and diagnosis of renal dysfunction in the ICU
    Jay L Koyner
    Section of Nephrology, Department of Internal Medicine, University of Chicago, Chicago, IL 60637, USA
    Chest 141:1584-94. 2012
  2. pmc Urinary cystatin C and acute kidney injury after cardiac surgery
    Jay L Koyner
    Section of Nephrology, Department of Medicine, University of Chicago, Pritzker School of Medicine, Chicago, IL, USA
    Am J Kidney Dis 61:730-8. 2013
  3. pmc Postoperative biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery
    Chirag R Parikh
    Section of Nephrology, Yale University and VAMC, 950 Campbell Avenue, Mail Code 151B, West Haven, CT 06516, USA
    J Am Soc Nephrol 22:1737-47. 2011
  4. pmc Biomarkers predict progression of acute kidney injury after cardiac surgery
    Jay L Koyner
    Section of Nephrology, Department of Medicine, University of Chicago, Pritzker School of Medicine, Illinois, USA
    J Am Soc Nephrol 23:905-14. 2012
  5. pmc Preoperative serum brain natriuretic peptide and risk of acute kidney injury after cardiac surgery
    Uptal D Patel
    Section of Nephrology, Yale University and VAMC, 950 Campbell Ave, West Haven, CT 06516, USA
    Circulation 125:1347-55. 2012
  6. pmc Urine Biomarkers and Perioperative Acute Kidney Injury: The Impact of Preoperative Estimated GFR
    Jay L Koyner
    Section of Nephrology, Department of Medicine, University of Chicago, Pritzker School of Medicine, Chicago, IL
    Am J Kidney Dis 66:1006-14. 2015
  7. pmc Adjudication of etiology of acute kidney injury: experience from the TRIBE-AKI multi-center study
    Jay L Koyner
    Department of Internal Medicine, Program of Applied Translational Research, Yale University and Veterans Affairs Medical Center, 60 Temple Street, Suite 6C, New Haven, CT 06510, USA
    BMC Nephrol 15:105. 2014
  8. doi request reprint Clinical utility of biomarkers of AKI in cardiac surgery and critical illness
    Jay L Koyner
    Section of Nephrology, Department of Medicine, University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA
    Clin J Am Soc Nephrol 8:1034-42. 2013
  9. pmc Preoperative angiotensin-converting enzyme inhibitors and angiotensin receptor blocker use and acute kidney injury in patients undergoing cardiac surgery
    Steven G Coca
    Section of Nephrology, Yale University School of Medicine, VA CT Healthcare System, New Haven, CT, USA
    Nephrol Dial Transplant 28:2787-99. 2013
  10. pmc Postoperative biomarkers predict acute kidney injury and poor outcomes after adult cardiac surgery
    Chirag R Parikh
    Section of Nephrology, Yale University and Veterans Administration Medical Center, 950 Campbell Avenue, Mail Code 151B, West Haven, CT 06516, USA
    J Am Soc Nephrol 22:1748-57. 2011

Detail Information

Publications19

  1. pmc Assessment and diagnosis of renal dysfunction in the ICU
    Jay L Koyner
    Section of Nephrology, Department of Internal Medicine, University of Chicago, Chicago, IL 60637, USA
    Chest 141:1584-94. 2012
    ..These biomarkers, taken with recent clinical investigations, have laid the groundwork for the impending paradigm shift in risk stratifying and in diagnosing changes in renal function in the ICU...
  2. pmc Urinary cystatin C and acute kidney injury after cardiac surgery
    Jay L Koyner
    Section of Nephrology, Department of Medicine, University of Chicago, Pritzker School of Medicine, Chicago, IL, USA
    Am J Kidney Dis 61:730-8. 2013
    ..Urinary cystatin C (CysC) level is a biomarker of proximal tubule function and may increase earlier in AKI than serum creatinine level...
  3. pmc Postoperative biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery
    Chirag R Parikh
    Section of Nephrology, Yale University and VAMC, 950 Campbell Avenue, Mail Code 151B, West Haven, CT 06516, USA
    J Am Soc Nephrol 22:1737-47. 2011
    ..In conclusion, urine IL-18 and urine NGAL, but not plasma NGAL, associate with subsequent AKI and poor outcomes among children undergoing cardiac surgery...
  4. pmc Biomarkers predict progression of acute kidney injury after cardiac surgery
    Jay L Koyner
    Section of Nephrology, Department of Medicine, University of Chicago, Pritzker School of Medicine, Illinois, USA
    J Am Soc Nephrol 23:905-14. 2012
    ..69, P<0.0001). In conclusion, biomarkers measured on the day of AKI diagnosis improve risk stratification and identify patients at higher risk for progression of AKI and worse patient outcomes...
  5. pmc Preoperative serum brain natriuretic peptide and risk of acute kidney injury after cardiac surgery
    Uptal D Patel
    Section of Nephrology, Yale University and VAMC, 950 Campbell Ave, West Haven, CT 06516, USA
    Circulation 125:1347-55. 2012
    ..We conducted a prospective study to evaluate whether preoperative brain natriuretic peptide (BNP) levels predict postoperative AKI among patients undergoing cardiac surgery...
  6. pmc Urine Biomarkers and Perioperative Acute Kidney Injury: The Impact of Preoperative Estimated GFR
    Jay L Koyner
    Section of Nephrology, Department of Medicine, University of Chicago, Pritzker School of Medicine, Chicago, IL
    Am J Kidney Dis 66:1006-14. 2015
    ..The interaction between baseline kidney function and the performance of biomarkers of acute kidney injury (AKI) on the development of AKI is unclear...
  7. pmc Adjudication of etiology of acute kidney injury: experience from the TRIBE-AKI multi-center study
    Jay L Koyner
    Department of Internal Medicine, Program of Applied Translational Research, Yale University and Veterans Affairs Medical Center, 60 Temple Street, Suite 6C, New Haven, CT 06510, USA
    BMC Nephrol 15:105. 2014
    ..However minimal data exists on the adjudication process in the setting of Acute Kidney Injury (AKI) as well as the ability to judge different etiologies (e.g. Acute Tubular Necrosis (ATN), Pre-renal Azotemia (PRA))...
  8. doi request reprint Clinical utility of biomarkers of AKI in cardiac surgery and critical illness
    Jay L Koyner
    Section of Nephrology, Department of Medicine, University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA
    Clin J Am Soc Nephrol 8:1034-42. 2013
    ....
  9. pmc Preoperative angiotensin-converting enzyme inhibitors and angiotensin receptor blocker use and acute kidney injury in patients undergoing cardiac surgery
    Steven G Coca
    Section of Nephrology, Yale University School of Medicine, VA CT Healthcare System, New Haven, CT, USA
    Nephrol Dial Transplant 28:2787-99. 2013
    ..Whether the same is true for 'structural' AKI, measured with new urinary biomarkers, is unknown...
  10. pmc Postoperative biomarkers predict acute kidney injury and poor outcomes after adult cardiac surgery
    Chirag R Parikh
    Section of Nephrology, Yale University and Veterans Administration Medical Center, 950 Campbell Avenue, Mail Code 151B, West Haven, CT 06516, USA
    J Am Soc Nephrol 22:1748-57. 2011
    ..In conclusion, urine IL-18, urine NGAL, and plasma NGAL associate with subsequent AKI and poor outcomes among adults undergoing cardiac surgery...
  11. pmc Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury
    Jay L Koyner
    Section of Nephrology, Department of Medicine, University of Chicago, Chicago, Illinois, USA
    Clin J Am Soc Nephrol 5:2154-65. 2010
    ..The diagnostic and prognostic utility of novel and traditional AKI biomarkers was evaluated during a prospective study of 123 adults undergoing cardiac surgery...
  12. pmc Acute kidney injury and mortality following ventricular assist device implantation
    Abhijit Naik
    Section of Nephrology, University of Chicago, Chicago, Ill, USA
    Am J Nephrol 39:195-203. 2014
    ..We sought to evaluate the incidence, risk factors and short- and long-term all-cause mortality of patients with AKI following VAD implantation...
  13. pmc Urine cystatin C as a biomarker of proximal tubular function immediately after kidney transplantation
    Isaac E Hall
    Department of Medicine, Section of Nephrology, Yale University School of Medicine and the Clinical Epidemiology Research Center, VAMC, New Haven, CT 06516, USA
    Am J Nephrol 33:407-13. 2011
    ..Clinical methods to predict allograft function soon after kidney transplantation are ineffective...
  14. pmc Tissue Inhibitor Metalloproteinase-2 (TIMP-2)⋅IGF-Binding Protein-7 (IGFBP7) Levels Are Associated with Adverse Long-Term Outcomes in Patients with AKI
    Jay L Koyner
    Section of Nephrology, Department of Medicine, University of Chicago, Chicago, Illinois
    J Am Soc Nephrol 26:1747-54. 2015
    ..32 to 3.53 for levels>2.0; P=0.002). In conclusion, [TIMP-2]⋅[IGFBP7] measured early in the setting of critical illness may identify patients with AKI at increased risk for mortality or receipt of RRT over the next 9 months. ..
  15. pmc Furosemide Stress Test and Biomarkers for the Prediction of AKI Severity
    Jay L Koyner
    Section of Nephrology, Department of Medicine, University of Chicago, Chicago, Illinois
    J Am Soc Nephrol 26:2023-31. 2015
    ..Using a FST in patients with increased biomarker levels improves risk stratification, although further research is needed...
  16. pmc The effects of heart failure on renal function
    Suneel M Udani
    Department of Medicine, University of Chicago, IL 60637, USA
    Cardiol Clin 28:453-65. 2010
    ..Novel therapeutic interventions using extracorporeal therapy and antagonists of the adenosine pathway show promise and require further investigation...
  17. ncbi request reprint Effect of blood pressure lowering on markers of kidney disease progression
    Suneel M Udani
    Section of Nephrology, University of Chicago, Chicago, IL 60637, USA
    Curr Hypertens Rep 11:368-74. 2009
    ..The identification and use of novel markers of kidney injury to assess the impact of antihyper-tensive therapy may yield clearer direction with regard to optimal management of hypertension in the setting of CKD...
  18. pmc Autologous creatinine clearance in a case of necrotizing fasciitis and anuria
    Michael T Eadon
    Section of Nephrology, University of Chicago, IL, USA
    Am J Nephrol 35:225-9. 2012
    ..It further reinforces the imperfection in using serum creatinine as a primary measure of glomerular filtration rate...
  19. pmc Urinary cystatin C as an early biomarker of acute kidney injury following adult cardiothoracic surgery
    Jay L Koyner
    Section of Nephrology, Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    Kidney Int 74:1059-69. 2008
    ..Our study suggests that urinary CyC and NGAL are superior to conventional and novel plasma markers in the early diagnosis of acute kidney injury following adult cardiac surgery...