L G Koniaris
Affiliation: University of Rochester
- Cytokine-responsive gene-2/IFN-inducible protein-10 expression in multiple models of liver and bile duct injury suggests a role in tissue regenerationL G Koniaris
Departments of Molecular Biology and Genetics and Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
J Immunol 167:399-406. 2001..Our data demonstrate that induction of Crg-2 occurs in several distinct models of liver injury and regeneration, and suggest a role for CRG-2/IP-10 in these processes...
- Capnographic monitoring of ventilatory status during moderate (conscious) sedationL G Koniaris
Department of Surgery, University of Rochester School of Medicine and Dentistry, Box SURG, 601 Elmwood Avenue, Rochester, NY 14562, USA
Surg Endosc 17:1261-5. 2003..Moderate (conscious) sedation is required to perform endoscopic procedures. Capnography provides a means for continuous, real-time monitoring of ventilation and may also decrease the incidence of oversedation...
- Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injuryE C Hsiao
Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Mol Cell Biol 20:3742-51. 2000..Our findings suggest either that Gdf15 does not have a regulatory role in liver injury and regeneration or that Gdf15 function within the liver is redundant with that of other signaling molecules...
- Benign rectal ulcer: an underground cause of inpatient lower gastrointestinal bleedingR J Hendrickson
Department of Surgery, University of Rochester School of Medicine, 601 Elmwood Avenue, Rochester, NY 14642, USA
Surg Endosc 17:1759-65. 2003..Although it is uncommon, significant bleeding per rectum presents one of the most difficult emergency problems. Bleeding from a rectal ulcer is not well recognized as a cause of such bleeding...
- Management of massive retroperitoneal hemorrhage from an adrenal tumorR J Hendrickson
Department of Surgery, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Endocr J 48:691-6. 2001..The possibility of a pheochromocytoma must always be entertained. Early recognition and treatment of patients with presumed adrenal insufficiency may decrease patient morbidity and mortality...
- Temporal CT changes after hepatic and renal interstitial radiotherapy in a canine modelS B Solomon
Department of Radiology, Johns Hopkins Hospital, Baltimore, MD 21287, USA
J Comput Assist Tomogr 25:74-80. 2001..The purpose of this work was to define the temporal CT characteristics of hepatic and renal ablation following point-source radioablation utilizing a low energy, photon X-ray source emitted from a miniature probe...
- TNF mediates a murine model of Addison's crisisL G Koniaris
Department of Molecular Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Shock 15:29-34. 2001..02). In summary, both LPS-induced Addison's crisis and chronic adrenal insufficiency are disorders of TNF disregulation. Based upon these data, therapeutic strategies targeted at controlling TNF in adrenal insufficiency are suggested...
- Dynamic retention: a technique for closure of the complex abdomen in critically ill patientsL G Koniaris
Department of Surgery, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Rochester, NY 14562, USA
Arch Surg 136:1359-62; discussion 1363. 2001..We observed a low complication rate. In properly selected patients, this technique avoids the use of mesh or additional surgical procedures such as skin grafting or plastic surgical reconstruction of the abdominal wall...
- Gamma probe-confirmed laparoscopic accessory splenectomyR J Hendrickson
Department of Surgery, Strong Memorial Hospital, University of Rochester Medical Center, 601 Elmwood Avenue, Box SURG, Rochester, NY 14602, USA
Surg Endosc 16:1364. 2002..We report an unusual case of an accessory spleen causing ITP in a patient who had undergone a splenectomy for Hodgkin's disease 10 years earlier. The patient underwent hand-held gamma-probe-assisted laparoscopic accessory splenectomy...
- Interferon-inducible protein-10 identified as a mediator of tumor necrosis in vivoC Sgadari
Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 93:13791-6. 1996..Thus, IP-10 is an antitumor agent that promotes damage in established tumor vasculature and causes tissue necrosis in human Burkitt lymphomas established subcutaneously in athymic mice...
- Human Mig chemokine: biochemical and functional characterizationF Liao
Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
J Exp Med 182:1301-14. 1995..It is likely that HuMig plays a role in T cell trafficking and perhaps in other aspects of the physiology of activated T cells...