Genomes and Genes
Affiliation: University of California
- Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signalingLutz Kockel
Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts, United States of America
PLoS Genet 6:e1000990. 2010..These results illustrate how the Akt-TOR pathway dynamically adapts the routing of negative feedback in response to the activity load of its signaling circuit in vivo...
- The PDGF/VEGF receptor controls blood cell survival in DrosophilaKatja Brückner
Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
Dev Cell 7:73-84. 2004..This function of PVR shows striking conservation with mammalian hematopoiesis and establishes Drosophila as a model to study hematopoietic cell survival in development and disease...