Bruce F Kimler
Affiliation: University of Kansas Medical Center
- Depletion of L-ascorbic acid alternating with its supplementation in the treatment of patients with acute myeloid leukemia or myelodysplastic syndromesChan H Park
Cancer Center and Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
Eur J Haematol 83:108-18. 2009....
- Mammographic density does not correlate with Ki-67 expression or cytomorphology in benign breast cells obtained by random periareolar fine needle aspiration from women at high risk for breast cancerQamar J Khan
University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, Kansas 66160, USA
Breast Cancer Res 9:R35. 2007..It is not known whether there is a correlation between mammographic density and Ki-67 expression in benign breast ductal cells obtained by RPFNA...
- L-ascorbic acid represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60Seong Su Han
Samsung Medical Center, and Sungkyunkwan University School of Medicine, Seoul 135 710, Korea
J Cell Biochem 93:257-70. 2004..In conclusion, our data suggest that LAA exerts its anti-tumor activity through downregulation of NF-kappaB activity and COX-2 expression, and these inhibitory effects can be enhanced by co-treatment with As2O3...
- L-Ascorbic acid induces apoptosis in acute myeloid leukemia cells via hydrogen peroxide-mediated mechanismsSeyeon Park
Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135 710, Republic of Korea
Int J Biochem Cell Biol 36:2180-95. 2004..In conclusion, LAA can induce apoptosis in AML cells, and this is clearly due to H(2)O(2) which accumulates intracellularly as a result of oxidation of reduced glutathione by LAA...