Ellen J Kim

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Mycosis fungoides and sezary syndrome: an update
    Ellen J Kim
    Department of Dermatology, University of Pennsylvania Health System, Philadelphia, 19104, USA
    Curr Oncol Rep 8:376-86. 2006
  2. doi request reprint Update on treatment of cutaneous T-cell lymphoma
    Jennifer M Gardner
    Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Curr Opin Oncol 21:131-7. 2009
  3. pmc Immunopathogenesis and therapy of cutaneous T cell lymphoma
    Ellen J Kim
    Department of Dermatology, University of Pennsylvania School of Medicine and The Wistar Institute, Philadelphia, Pennsylvania 19104, USA
    J Clin Invest 115:798-812. 2005
  4. doi request reprint Improvement in peripheral blood disease burden in patients with Sézary syndrome and leukemic mycosis fungoides after total skin electron beam therapy
    Rachel S Klein
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 68:972-7. 2013
  5. doi request reprint Total skin electron beam therapy may be associated with improvement of peripheral blood disease in Sézary syndrome
    Camille E Introcaso
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 58:592-5. 2008
  6. pmc Inhibition of cell-mediated immunity by the histone deacetylase inhibitor vorinostat: implications for therapy of cutaneous T-cell lymphoma
    Sasha Stephen
    Department of Dermatology, University of Pennsylvania and The Wistar Institute, Philadelphia, PA 19104, USA
    Am J Hematol 87:226-8. 2012
  7. doi request reprint High clinical response rate of Sezary syndrome to immunomodulatory therapies: prognostic markers of response
    Brian A Raphael
    Department of Dermatology, The Hospital at the University of Pennsylvania, Philadelphia, USA
    Arch Dermatol 147:1410-5. 2011
  8. doi request reprint CD8+ epidermotropic cytotoxic T-cell lymphoma with peripheral blood and central nervous system involvement
    Camille E Introcaso
    Department of Dermatology, Hospital of the University of Pennsylvania, 2 Maloney Bldg, 3400 Spruce St, Philadelphia, PA 19104, USA
    Arch Dermatol 144:1027-9. 2008
  9. ncbi request reprint High clinical response rate with multimodality immunomodulatory therapy for Sézary syndrome
    Stephen K Richardson
    Department of Dermatology, University of Pennsylvania, Philadelphia, USA
    Clin Lymphoma Myeloma 7:226-32. 2006
  10. doi request reprint A novel regimen of vorinostat with interferon gamma for refractory Sézary syndrome
    Jennifer M Gardner
    Department of Dermatology, Hospital of the University of Pennsylvania, 3600 Spruce Street, Philadelphia, PA 19146, USA
    J Am Acad Dermatol 61:112-6. 2009

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Mycosis fungoides and sezary syndrome: an update
    Ellen J Kim
    Department of Dermatology, University of Pennsylvania Health System, Philadelphia, 19104, USA
    Curr Oncol Rep 8:376-86. 2006
    ..This recent work has made a great impact on diagnosis, prognostication, and treatment. In this review, we survey the MF/SS published literature over the past year and highlight some of the important advances...
  2. doi request reprint Update on treatment of cutaneous T-cell lymphoma
    Jennifer M Gardner
    Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Curr Opin Oncol 21:131-7. 2009
    ..Numerous therapeutic options exist; however, many patients experience refractory disease and novel treatments are needed...
  3. pmc Immunopathogenesis and therapy of cutaneous T cell lymphoma
    Ellen J Kim
    Department of Dermatology, University of Pennsylvania School of Medicine and The Wistar Institute, Philadelphia, Pennsylvania 19104, USA
    J Clin Invest 115:798-812. 2005
    ....
  4. doi request reprint Improvement in peripheral blood disease burden in patients with Sézary syndrome and leukemic mycosis fungoides after total skin electron beam therapy
    Rachel S Klein
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 68:972-7. 2013
    ..Total skin electron beam (TSEB) radiation therapy is an extremely effective skin-directed therapy for these patients, but, until recently, it was thought not to signifcantly affect the peripheral blood malignant T-cell population...
  5. doi request reprint Total skin electron beam therapy may be associated with improvement of peripheral blood disease in Sézary syndrome
    Camille E Introcaso
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 58:592-5. 2008
    ..The data from these 4 patients illustrate the potential for total skin electron beam to be used as both a skin and blood tumor debulking agent, and not merely as a palliation for skin symptoms...
  6. pmc Inhibition of cell-mediated immunity by the histone deacetylase inhibitor vorinostat: implications for therapy of cutaneous T-cell lymphoma
    Sasha Stephen
    Department of Dermatology, University of Pennsylvania and The Wistar Institute, Philadelphia, PA 19104, USA
    Am J Hematol 87:226-8. 2012
    ..These findings raise concerns of increased susceptibility to infection in this high-risk population...
  7. doi request reprint High clinical response rate of Sezary syndrome to immunomodulatory therapies: prognostic markers of response
    Brian A Raphael
    Department of Dermatology, The Hospital at the University of Pennsylvania, Philadelphia, USA
    Arch Dermatol 147:1410-5. 2011
    ..To quantify response rates of Sézary syndrome (SS) to multimodality immunomodulatory therapy and to identify the important prognostic parameters that affect overall response to treatment...
  8. doi request reprint CD8+ epidermotropic cytotoxic T-cell lymphoma with peripheral blood and central nervous system involvement
    Camille E Introcaso
    Department of Dermatology, Hospital of the University of Pennsylvania, 2 Maloney Bldg, 3400 Spruce St, Philadelphia, PA 19104, USA
    Arch Dermatol 144:1027-9. 2008
    ..To our knowledge, involvement of peripheral blood or cerebrospinal fluid with a malignant population of CD8(+) cells demonstrated by flow cytometry and T-cell receptor gene rearrangement has not been previously described...
  9. ncbi request reprint High clinical response rate with multimodality immunomodulatory therapy for Sézary syndrome
    Stephen K Richardson
    Department of Dermatology, University of Pennsylvania, Philadelphia, USA
    Clin Lymphoma Myeloma 7:226-32. 2006
    ....
  10. doi request reprint A novel regimen of vorinostat with interferon gamma for refractory Sézary syndrome
    Jennifer M Gardner
    Department of Dermatology, Hospital of the University of Pennsylvania, 3600 Spruce Street, Philadelphia, PA 19146, USA
    J Am Acad Dermatol 61:112-6. 2009
    ..We present 3 cases of refractory Sézary syndrome in which the combination of vorinostat and interferon gamma was well tolerated and produced significant clinical improvement. The potential immunologic basis for this is discussed...
  11. doi request reprint Primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma
    Rachel H Gormley
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Am Acad Dermatol 62:300-7. 2010
    ....
  12. pmc Clinical and in vitro resistance to bexarotene in adult T-cell leukemia: loss of RXR-alpha receptor
    Julie H Lin
    Department of Dermatology, University of Pennsylvania, Philadelphia 19104, USA
    Blood 112:2484-8. 2008
    ..Our findings indicate that reduced expression of the RXR-alpha receptor subunit may represent a mechanism for resistance to bexarotene in T-cell malignancies...
  13. pmc Reliability and convergent validity of the cutaneous sarcoidosis activity and morphology instrument for assessing cutaneous sarcoidosis
    Misha Rosenbach
    Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA
    JAMA Dermatol 149:550-6. 2013
    ....
  14. pmc Topical chemotherapy in cutaneous T-cell lymphoma: positive results of a randomized, controlled, multicenter trial testing the efficacy and safety of a novel mechlorethamine, 0.02%, gel in mycosis fungoides
    Stuart R Lessin
    Division of Dermatology, Department of Pathology, Fox Chase Cancer Center, University of Pennsylvania, Philadelphia, USA
    JAMA Dermatol 149:25-32. 2013
    ..Tumor response and adverse events were assessed every month between months 1 and 6 and every 2 months between months 7 and 12. Serum drug levels were evaluated in a subset of patients...
  15. doi request reprint Peripheral blood findings in erythrodermic patients: importance for the differential diagnosis of Sézary syndrome
    Arielle R Nagler
    School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 66:503-8. 2012
    ..This review evaluates current data on the usefulness and limitations of specific peripheral blood markers detected by flow cytometry and T-cell receptor gene rearrangement polymerase chain reaction...
  16. ncbi request reprint Low-dose bexarotene and low-dose interferon alfa-2b for adult T-cell leukemia/lymphoma associated with human T-lymphotropic virus 1
    Stephen Richardson
    Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    Arch Dermatol 141:301-4. 2005
  17. ncbi request reprint Extracorporeal photopheresis and multimodality immunomodulatory therapy in the treatment of cutaneous T-cell lymphoma
    Stephen K Richardson
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Cutan Med Surg 7:8-12. 2003
  18. doi request reprint Validity assessment of the cutaneous T-cell lymphoma severity index to predict prognosis in advanced mycosis fungoides/Sézary syndrome
    Katherine G Evans
    Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    J Am Acad Dermatol 64:682-9. 2011
    ....
  19. doi request reprint Gain of CD26 expression on the malignant T-cells in relapsed erythrodermic leukemic mycosis fungoides
    Filiberto Cedeno-Laurent
    Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, 2 Maloney, 3600 Spruce St, Philadelphia, PA, 19104, United States
    J Cutan Pathol . 2017
    ..Interestingly, quantitative expression of the sialomucin, CD164, mirrored her clinical picture, thus favoring its reliability as a novel biomarker in CTCL...
  20. pmc Improved pruritus correlates with lower levels of IL-31 in CTCL patients under different therapeutic modalities
    Filiberto Cedeno-Laurent
    Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA Electronic address
    Clin Immunol 158:1-7. 2015
    ....
  21. doi request reprint Stem cell transplantation in advanced cutaneous T-cell lymphoma
    Camille E Introcaso
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Am Acad Dermatol 58:645-9. 2008
    ....
  22. ncbi request reprint Progressive multifocal leukoencephalopathy from JC virus in a patient with advanced mycosis fungoides
    Jin Lee
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Am Acad Dermatol 57:893-5. 2007
    ..We report a case of progressive multifocal leukoencephalopathy developing in an advanced mycosis fungoides patient without prior history of immunosuppressive therapy...
  23. ncbi request reprint Lichen sclerosus et atrophicus-like graft-versus-host disease post stem cell transplant
    Jennifer L Weinberg
    University of Pennsylvania School of Medicine, USA
    Dermatol Online J 15:4. 2009
    ..Lichen sclerosus et atrophicus-like cGVHD may represent a phase in this continuum or a distinct sub-type of disease. Remaining cognizant of the potential manifestations of disease is key for prompt recognition and proper treatment...
  24. pmc Marginal zone lymphoma-derived interfollicular diffuse large B-cell lymphoma harboring 20q12 chromosomal deletion and missense mutation of BIRC3 gene: a case report
    Joseph Hatem
    Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, 7 E Gates Pavilion, 3400 Spruce Street, Philadelphia, 19104 4283, PA, USA
    Diagn Pathol 11:137. 2016
    ..Here we describe a rare case of a diagnostically challenging DLBCL-IF involving a lymph node in a patient with a prior history of lymphadenopathy for several years and MZL involving skin...
  25. doi request reprint Granuloma annulare associated with cutaneous marginal zone lymphoma: a case linking a hematologic malignancy with granulomatous dermatitis
    Karolyn A Wanat
    Department of Dermatology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Dermatopathol 34:844-6. 2012
    ..This case highlights the importance of considering both B- and T-cell dyscrasias in the case of refractory or extensive granulomatous lesions and the importance of histopathologic examination in the evaluation of these lesions...
  26. pmc Tumor necrosis factor inhibitor-associated dermatomyositis
    Rachel Klein
    Department of Medicine, Division of Rheumatology, University of Pennsylvania School of Medicine, Perelman Center for Advanced Medicine, First Floor South Pavilion, 3400 Civic Center Blvd, Philadelphia, PA 19104, USA
    Arch Dermatol 146:780-4. 2010
    ..Their symptoms persisted after discontinuation of the treatment with the TNF inhibitors but responded to treatment with corticosteroids and immunosuppressive medications...
  27. ncbi request reprint Low-dose radiotherapy for primary cutaneous anaplastic large-cell lymphoma while on low-dose methotrexate
    Christine M Cornejo
    Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, USA
    Cutis 98:253-256. 2016
    ....
  28. doi request reprint Topical Carmustine as Monotherapy or as Multimodality Therapy for Folliculotropic Mycosis Fungoides
    Kelly M MacArthur
    Department of Dermatology, Johns Hopkins University, 601 North Caroline Street, 8 Floor, Baltimore, Maryland, 21287, USA
    Acta Derm Venereol . 2016
    ..is missing (Short communication)...
  29. doi request reprint CD30 positive atypical lymphocytes in perniosis: a potential histopathologic pitfall in a benign condition
    Paul R Massey
    Perelman School of Medicine, Philadelphia, PA Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA and Department of Pediatrics, Section of Dermatology, Children s Hospital of Philadelphia, Philadelphia, PA
    Am J Dermatopathol 36:730-3. 2014
    ..Dermatopathologists must be aware of this potential histologic pattern in perniosis to prevent misdiagnosis and overtreatment of this condition...
  30. ncbi request reprint Modulation of vascular endothelial growth factor receptors in melanocytes
    Ellen J Kim
    Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
    Exp Dermatol 14:625-33. 2005
    ..Prolonged culture (>8 weeks) in the presence of phorbol ester abrogates VEGFR-2 expression, explaining previous reports that Mc do not express VEGFR-1 and VEGFR-2. These data suggest that VEGF may play a role in Mc behavior in skin...
  31. ncbi request reprint The addition of interferon gamma to oral bexarotene therapy with photopheresis for Sézary syndrome
    Karen S McGinnis
    Arch Dermatol 141:1176-8. 2005
  32. ncbi request reprint CD8+ lymphoma in a patient with human immunodeficiency virus
    Chad M Hivnor
    Arch Dermatol 141:1321-2. 2005
  33. ncbi request reprint Vision loss following denileukin diftitox treatment: a case report of possible posterior ischemic optic neuropathy
    Meyeon Park
    Leuk Lymphoma 48:808-11. 2007
  34. ncbi request reprint Multiple facial papules in an adult
    Ellen J Kim
    New England Medical Center, Boston, Mass, USA
    Arch Dermatol 139:215-20. 2003