Michelle Khine

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Shrinky-Dink microfluidics: rapid generation of deep and rounded patterns
    Anthony Grimes
    School of Engineering, University of California, Merced, USA
    Lab Chip 8:170-2. 2008
  2. doi request reprint Shrinky-Dink microfluidics: 3D polystyrene chips
    Chi Shuo Chen
    School of Engineering, University of California, Merced, USA
    Lab Chip 8:622-4. 2008
  3. doi request reprint Tunable shrink-induced honeycomb microwell arrays for uniform embryoid bodies
    Diep Nguyen
    Department of Biomedical Engineering, University of California, Irvine, CA, USA
    Lab Chip 9:3338-44. 2009
  4. pmc Shrink-film microfluidic education modules: Complete devices within minutes
    Diep Nguyen
    Department of Biomedical Engineering, University of California, Irvine, California 92697, USA
    Biomicrofluidics 5:22209. 2011
  5. doi request reprint Shrink-induced single-cell plastic microwell array
    Valerie Lew
    Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA
    J Lab Autom 16:450-6. 2011
  6. doi request reprint Plasma free reversible and irreversible microfluidic bonding
    M Chu
    Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA
    Lab Chip 17:267-273. 2017
  7. pmc Multi-scale silica structures for improved HIV-1 Capsid (p24) antigen detection
    Sophia Lin
    Department of Chemical Engineering and Materials Science, University of California, Irvine, Irvine, CA 92697, USA
    Analyst 141:4181-8. 2016
  8. pmc Shrink-induced superhydrophobic and antibacterial surfaces in consumer plastics
    Lauren R Freschauf
    Department of Biomedical Engineering, University of California Irvine, Irvine, California, USA
    PLoS ONE 7:e40987. 2012
  9. doi request reprint Flexible shrink-induced high surface area electrodes for electrochemiluminescent sensing
    Jonathan D Pegan
    Department of Biomedical Engineering, University of California, Irvine, Irvine, CA 92697, USA
    Lab Chip 13:4205-9. 2013
  10. pmc Unconventional low-cost fabrication and patterning techniques for point of care diagnostics
    Himanshu Sharma
    Department of Chemical Engineering and Materials Science, University of California, Irvine, CA, USA
    Ann Biomed Eng 39:1313-27. 2011

Collaborators

  • Luke P Lee
  • Kara E McCloskey
  • Ronald A Li
  • Enrico Gratton
  • Wei Chun Chin
  • Arnold D Kim
  • Diep Nguyen
  • Jonathan D Pegan
  • Aaron Chen
  • Valerie Lew
  • Himanshu Sharma
  • Joshua Kim
  • Douglas Taylor
  • Maureen Long
  • M Chu
  • Anthony Grimes
  • Sophia Lin
  • Thao Nguyen
  • Sun Jun Park
  • Michael Chu
  • Mark Bachman
  • Elizabeth Hinde
  • Lauren R Freschauf
  • Jolie McLane
  • Jesus Isaac Luna
  • Deborah K Lieu
  • Charless C Fowlkes
  • Jonathan Pegan
  • Chi Shuo Chen
  • David N Breslauer
  • E K Lee
  • T T Nguyen
  • J L Morival
  • Vasan Venugopalan
  • Akshay Paul
  • Jasmine Zhang
  • Per Niklas Hedde
  • Eugene Lee
  • Charless Fowlkes
  • Roger Tu
  • Anna Grosberg
  • Kevin Santiago
  • Adrienne Y Ho
  • Francesco Cardarelli
  • Jesus Ciriza
  • Marcos E Garcia-Ojeda
  • Roger J Hajjar
  • Ioannis Karakikes
  • Jiaxian Wang
  • Anthony Herren
  • Ajay Gopinathan
  • Elliot Botvinick
  • Marco Kong
  • Lauren Freschauf
  • Kun Qian
  • Matt Lehmann
  • Kurt Halverson
  • Steve Botzet
  • David Dyer
  • Jerald Rasmussen
  • Nizilla Norouzi
  • Jennifer O Manilay
  • Guangxin Xiang
  • Silin Sa
  • Brent Rich
  • Jesus I Luna

Detail Information

Publications21

  1. ncbi request reprint Shrinky-Dink microfluidics: rapid generation of deep and rounded patterns
    Anthony Grimes
    School of Engineering, University of California, Merced, USA
    Lab Chip 8:170-2. 2008
    ..Finally, we demonstrate the utility of this simple microfabrication approach by fabricating a functional gradient generator. The whole process--from device design conception to working device--can be completed within minutes...
  2. doi request reprint Shrinky-Dink microfluidics: 3D polystyrene chips
    Chi Shuo Chen
    School of Engineering, University of California, Merced, USA
    Lab Chip 8:622-4. 2008
    ..Design conception to fully functional chips can thus be completed within minutes...
  3. doi request reprint Tunable shrink-induced honeycomb microwell arrays for uniform embryoid bodies
    Diep Nguyen
    Department of Biomedical Engineering, University of California, Irvine, CA, USA
    Lab Chip 9:3338-44. 2009
    ..In addition, these microwells are easily adaptable and scalable to most standard well plates and easily integrated into commercial liquid handling systems to provide an inexpensive and easy high throughput compound screening platform...
  4. pmc Shrink-film microfluidic education modules: Complete devices within minutes
    Diep Nguyen
    Department of Biomedical Engineering, University of California, Irvine, California 92697, USA
    Biomicrofluidics 5:22209. 2011
    ....
  5. doi request reprint Shrink-induced single-cell plastic microwell array
    Valerie Lew
    Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA
    J Lab Autom 16:450-6. 2011
    ..We calibrated the loading procedure with fluorescent microbeads. Finally, we demonstrate the utility of the wells by loading fluorescently labeled single human embryonic stem cells into the wells...
  6. doi request reprint Plasma free reversible and irreversible microfluidic bonding
    M Chu
    Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA
    Lab Chip 17:267-273. 2017
    ..When combined with our Shrinky-Dink microfluidic prototyping, complete microfluidic device fabrication can be performed without the need for any capital equipment, making microfluidics accessible to the classroom...
  7. pmc Multi-scale silica structures for improved HIV-1 Capsid (p24) antigen detection
    Sophia Lin
    Department of Chemical Engineering and Materials Science, University of California, Irvine, Irvine, CA 92697, USA
    Analyst 141:4181-8. 2016
    ..Finally, we show that the SiO2 substrates serve as a suitable platform for disease diagnostics, and show improved limits of detection (LOD) for the human immunodeficiency virus type 1 (HIV-1) p24 antigen. ..
  8. pmc Shrink-induced superhydrophobic and antibacterial surfaces in consumer plastics
    Lauren R Freschauf
    Department of Biomedical Engineering, University of California Irvine, Irvine, California, USA
    PLoS ONE 7:e40987. 2012
    ..coli) bacteria growth on our structured plastic surfaces...
  9. doi request reprint Flexible shrink-induced high surface area electrodes for electrochemiluminescent sensing
    Jonathan D Pegan
    Department of Biomedical Engineering, University of California, Irvine, Irvine, CA 92697, USA
    Lab Chip 13:4205-9. 2013
    ....
  10. pmc Unconventional low-cost fabrication and patterning techniques for point of care diagnostics
    Himanshu Sharma
    Department of Chemical Engineering and Materials Science, University of California, Irvine, CA, USA
    Ann Biomed Eng 39:1313-27. 2011
    ..Though still in their infancy, these technologies hold potential to improve upon the resolution, sensitivity, flexibility, and cost-savings over more traditional approaches...
  11. doi request reprint Shrink-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives
    Aaron Chen
    Department of Chemical Engineering and Material Science, University of California, Irvine, 92697, USA
    Adv Mater 23:5785-91. 2011
    ..Using this substrate, the functional alignment of human embryonic stem cell derived cardiomyocytes is demonstrated...
  12. pmc Highly stretchable wrinkled gold thin film wires
    Joshua Kim
    Department of Chemical Engineering and Materials Science, University of California, Irvine, California 92697, USA
    Appl Phys Lett 108:061901. 2016
    ..We propose that these wrinkled metal thin film wires are an attractive alternative to conventional wires for wearable applications...
  13. doi request reprint Better shrinkage than Shrinky-Dinks
    Diep Nguyen
    Department of Biomedical Engineering, UC Irvine, USA
    Lab Chip 10:1623-6. 2010
    ..In this technical note, we demonstrate the ability to rapidly and easily create unique microstructures, increase microarray feature density, and even induce self-assembled integrated metallic nanostructures with these shrink wrap films...
  14. ncbi request reprint Single-cell electroporation arrays with real-time monitoring and feedback control
    Michelle Khine
    School of Engineering, University of California, Merced, CA, USA
    Lab Chip 7:457-62. 2007
    ....
  15. doi request reprint Shrink film patterning by craft cutter: complete plastic chips with high resolution/high-aspect ratio channel
    Douglas Taylor
    Department of Biomedical Engineering, University of California, Irvine, USA
    Lab Chip 10:2472-5. 2010
    ..Full device characterization including channel consistency, optical properties, and bonding strength are assessed in this technical note...
  16. doi request reprint Integrated platform for functional monitoring of biomimetic heart sheets derived from human pluripotent stem cells
    Aaron Chen
    Department of Chemical Engineering and Materials Science, University of California, Irvine, CA, USA
    Biomaterials 35:675-83. 2014
    ..This simple and low-cost platform could thus be a powerful tool for longitudinal assays as well as an effective tool for drug screening and basic cardiac research...
  17. doi request reprint Scattering of light by molecules over a rough surface
    Maureen Long
    School of Natural Sciences, 5200 North Lake Road, University of California, Merced, Merced, California 95343, USA
    J Opt Soc Am A Opt Image Sci Vis 27:1002-11. 2010
    ..We apply this general theory for the special case of point scatterers and a slightly rough surface with homogeneous Dirichlet and Neumann boundary conditions. We show examples that demonstrate the utility of this theory...
  18. ncbi request reprint Skin-mountable stretch sensor for wearable health monitoring
    Jonathan D Pegan
    Materials and Manufacturing Technology, University of California Irvine, Irvine, CA, USA
    Nanoscale 8:17295-17303. 2016
    ..The possibility of using such a sensor for real-time respiratory monitoring by measuring chest wall displacement and correlating with lung volume is demonstrated...
  19. pmc Tracking the mechanical dynamics of human embryonic stem cell chromatin
    Elizabeth Hinde
    Laboratory for Fluorescence Dynamics, Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA
    Epigenetics Chromatin 5:20. 2012
    ..Here, we present a new tracking-based method which can detect high frequency chromatin movement and quantify the mechanical dynamics of chromatin in live cells...
  20. doi request reprint Multiscale biomimetic topography for the alignment of neonatal and embryonic stem cell-derived heart cells
    Jesus Isaac Luna
    School of Engineering, University of California, Merced, California 95343, USA
    Tissue Eng Part C Methods 17:579-88. 2011
    ....
  21. ncbi request reprint A single cell electroporation chip
    Michelle Khine
    Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, CA 94720, USA
    Lab Chip 5:38-43. 2005
    ....