Atsushi Kasai

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi [Pathological role of apelin in angiogenic eye disease]
    Atsushi Kasai
    Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan
    Yakugaku Zasshi 131:1201-6. 2011
  2. pmc Apelin deficiency accelerates the progression of amyotrophic lateral sclerosis
    Atsushi Kasai
    Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan
    PLoS ONE 6:e23968. 2011
  3. doi Laser-induced choroidal neovascularization in mice attenuated by deficiency in the apelin-APJ system
    Chikako Hara
    Department of Ophthalmology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Invest Ophthalmol Vis Sci 54:4321-9. 2013
  4. doi Apelin is a crucial factor for hypoxia-induced retinal angiogenesis
    Atsushi Kasai
    Department of Pharmacotherapeutics, Setsunan University, Hirakata, Osaka 565 0871, Japan
    Arterioscler Thromb Vasc Biol 30:2182-7. 2010
  5. doi Dopamine inhibits lipopolysaccharide-induced nitric oxide production through the formation of dopamine quinone in murine microglia BV-2 cells
    Yasuhiro Yoshioka
    Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45 1 Nagaotoge cho, Hirakata, Osaka 573 0101, Japan Electronic address
    J Pharmacol Sci 130:51-9. 2016
  6. doi Identification of the role of bone morphogenetic protein (BMP) and transforming growth factor-β (TGF-β) signaling in the trajectory of serotonergic differentiation in a rapid assay in mouse embryonic stem cells in vitro
    Atsushi Yamasaki
    Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan
    J Neurochem 132:418-28. 2015
  7. pmc Inhibition of apelin expression switches endothelial cells from proliferative to mature state in pathological retinal angiogenesis
    Atsushi Kasai
    Interdisciplinary Program for Biomedical Sciences, Institute for Academic Initiatives, Osaka University, 1 6 Yamadaoka, Suita, Osaka 565 0871, Japan
    Angiogenesis 16:723-34. 2013
  8. ncbi Caspase-4 directly activates caspase-9 in endoplasmic reticulum stress-induced apoptosis in SH-SY5Y cells
    Akiko Yamamuro
    Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka 573 0101, Japan
    J Pharmacol Sci 115:239-43. 2011
  9. ncbi Nitric oxide inhibits lipopolysaccharide-induced inducible nitric oxide synthase expression and its own production through the cGMP signaling pathway in murine microglia BV-2 cells
    Yasuhiro Yoshioka
    Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan
    J Pharmacol Sci 113:153-60. 2010
  10. pmc PACAP enhances axon outgrowth in cultured hippocampal neurons to a comparable extent as BDNF
    Katsuya Ogata
    Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Yamadaoka, Suita, Osaka, Japan
    PLoS ONE 10:e0120526. 2015

Collaborators

Detail Information

Publications13

  1. ncbi [Pathological role of apelin in angiogenic eye disease]
    Atsushi Kasai
    Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan
    Yakugaku Zasshi 131:1201-6. 2011
    ..Taken together, these findings clearly suggest that apelin/APJ system may be a crucial factor for pathological retinal angiogenesis. Inhibition of this system could offer new therapeutic opportunities against ischemic retinopathy...
  2. pmc Apelin deficiency accelerates the progression of amyotrophic lateral sclerosis
    Atsushi Kasai
    Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan
    PLoS ONE 6:e23968. 2011
    ..These results suggest that apelin/APJ system in the spinal cord has a neuroprotective effect against the pathogenesis of ALS...
  3. doi Laser-induced choroidal neovascularization in mice attenuated by deficiency in the apelin-APJ system
    Chikako Hara
    Department of Ophthalmology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Invest Ophthalmol Vis Sci 54:4321-9. 2013
    ..To investigate the role of the apelin-APJ system in the development of choroidal neovascularization (CNV)...
  4. doi Apelin is a crucial factor for hypoxia-induced retinal angiogenesis
    Atsushi Kasai
    Department of Pharmacotherapeutics, Setsunan University, Hirakata, Osaka 565 0871, Japan
    Arterioscler Thromb Vasc Biol 30:2182-7. 2010
    ..To investigate the role of endogenous apelin in pathological retinal angiogenesis...
  5. doi Dopamine inhibits lipopolysaccharide-induced nitric oxide production through the formation of dopamine quinone in murine microglia BV-2 cells
    Yasuhiro Yoshioka
    Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, 45 1 Nagaotoge cho, Hirakata, Osaka 573 0101, Japan Electronic address
    J Pharmacol Sci 130:51-9. 2016
    ..These results suggest that DA attenuates LPS-induced NO production through the formation of DAQ in BV-2 cells. ..
  6. doi Identification of the role of bone morphogenetic protein (BMP) and transforming growth factor-β (TGF-β) signaling in the trajectory of serotonergic differentiation in a rapid assay in mouse embryonic stem cells in vitro
    Atsushi Yamasaki
    Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan
    J Neurochem 132:418-28. 2015
    ..These results suggest that inhibition of BMP type I receptors and concomitant activation of transforming growth factor-β (TGF-β) receptor signaling are involved in the early trajectory of serotonergic differentiation. ..
  7. pmc Inhibition of apelin expression switches endothelial cells from proliferative to mature state in pathological retinal angiogenesis
    Atsushi Kasai
    Interdisciplinary Program for Biomedical Sciences, Institute for Academic Initiatives, Osaka University, 1 6 Yamadaoka, Suita, Osaka 565 0871, Japan
    Angiogenesis 16:723-34. 2013
    ....
  8. ncbi Caspase-4 directly activates caspase-9 in endoplasmic reticulum stress-induced apoptosis in SH-SY5Y cells
    Akiko Yamamuro
    Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka 573 0101, Japan
    J Pharmacol Sci 115:239-43. 2011
    ..These results suggest that caspase-4 directly activates caspase-9 by the processing of procaspase-9 at Asp-315 in ER stress-induced neuronal apoptosis...
  9. ncbi Nitric oxide inhibits lipopolysaccharide-induced inducible nitric oxide synthase expression and its own production through the cGMP signaling pathway in murine microglia BV-2 cells
    Yasuhiro Yoshioka
    Department of Pharmacotherapeutics, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan
    J Pharmacol Sci 113:153-60. 2010
    ..These results suggest that NO production by microglial cells is controlled by a negative feedback mechanism via the NO/cGMP signaling pathway...
  10. pmc PACAP enhances axon outgrowth in cultured hippocampal neurons to a comparable extent as BDNF
    Katsuya Ogata
    Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Yamadaoka, Suita, Osaka, Japan
    PLoS ONE 10:e0120526. 2015
    ....
  11. pmc Whole-exome sequencing and neurite outgrowth analysis in autism spectrum disorder
    Ryota Hashimoto
    Molecular Research Center for Children s Mental Development, United Graduate School of Child Development, Osaka University, Osaka, Japan
    J Hum Genet 61:199-206. 2016
    ....
  12. doi Central CRTH2, a second prostaglandin D2 receptor, mediates emotional impairment in the lipopolysaccharide and tumor-induced sickness behavior model
    Ryota Haba
    Laboratory of Molecular Neuropharmacology and Molecular Research Center for Children s Mental Development, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Suita, Osaka 565 0871, Japan, Department of Advanced Medicine and Development, Bio Medical Laboratories, Kawagoe, Saitama 350 1101, Japan, Human Gene Sciences Center, Tokyo Medical and Dental University, Tokyo 113 8510, Japan, Interdisciplinary Program for Biomedical Sciences, Institute for Academic Initiatives, Department of Psychiatry, Graduate School of Medicine, and iPS Cell based Research Project on Brain Neuropharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka 565 0871, Japan, and Faculty of Pharmaceutical Sciences, Hyogo University of Health Science, Kobe, Hyogo 650 8530, Japan
    J Neurosci 34:2514-23. 2014
    ..Our study provides the first evidence that central CRTH2 regulates specific emotional behaviors, and that CRTH2 antagonism has potential as a therapeutic target for behavioral symptoms associated with tumors and infectious diseases. ..
  13. pmc Increased behavioral and neuronal responses to a hallucinogenic drug in PACAP heterozygous mutant mice
    Keisuke Hazama
    Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan
    PLoS ONE 9:e89153. 2014
    ..Our findings provide insight into the neural mechanisms underlying impaired behavioral responses in which 5-HT2 receptors are implicated...