S B Joseph

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. doi request reprint HIV-1 target cells in the CNS
    Sarah B Joseph
    Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA
    J Neurovirol 21:276-89. 2015
  2. doi request reprint Effects of the [PSI+] prion on rates of adaptation in yeast
    S B Joseph
    Section of Integrative Biology, University of Texas, Austin, TX, USA
    J Evol Biol 21:773-80. 2008
  3. pmc Spontaneous mutations in diploid Saccharomyces cerevisiae: more beneficial than expected
    Sarah B Joseph
    Section of Integrative Biology, University of Texas, Austin, Texas 78712, USA
    Genetics 168:1817-25. 2004
  4. doi request reprint Spontaneous mutations in diploid Saccharomyces cerevisiae: another thousand cell generations
    David W Hall
    Department of Biological Sciences, University of Texas, Austin, TX 78712, USA
    Genet Res (Camb) 90:229-41. 2008

Collaborators

  • David W Hall
  • Rod Mahmoudizad
  • Andrew W Hurd

Detail Information

Publications4

  1. doi request reprint HIV-1 target cells in the CNS
    Sarah B Joseph
    Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA
    J Neurovirol 21:276-89. 2015
    ..Prior to the evolution of macrophage-tropic variants, the viruses that are predominately infecting T cells (R5 T cell-tropic) may infect macrophages at a low level and inefficiently, but this could contribute to the reservoir. ..
  2. doi request reprint Effects of the [PSI+] prion on rates of adaptation in yeast
    S B Joseph
    Section of Integrative Biology, University of Texas, Austin, TX, USA
    J Evol Biol 21:773-80. 2008
    ..A major factor affecting the rate of adaptation was initial fitness in the new environment: lines with low initial fitness evolved faster than lines with high initial fitness...
  3. pmc Spontaneous mutations in diploid Saccharomyces cerevisiae: more beneficial than expected
    Sarah B Joseph
    Section of Integrative Biology, University of Texas, Austin, Texas 78712, USA
    Genetics 168:1817-25. 2004
    ..The mutation rate was estimated as 6.3 x 10(-5) mutations per haploid genome per generation and the average heterozygous fitness effect of a mutation as 0.061. These estimates are compatible with previous estimates in yeast...
  4. doi request reprint Spontaneous mutations in diploid Saccharomyces cerevisiae: another thousand cell generations
    David W Hall
    Department of Biological Sciences, University of Texas, Austin, TX 78712, USA
    Genet Res (Camb) 90:229-41. 2008
    ..We also estimate the genome-wide mutation rate to be 13.7x10-5 mutations per haploid genome per cell generation and the absolute value of the average heterozygous effect of a mutation to be 7.3%...

Research Grants1

  1. The Causes and Consequences of Complementation and Selfishness in Viruses
    Sarah Joseph; Fiscal Year: 2008
    ..As a result, understanding these interactions in bacteriophage may provide insights into the evolution and pathogenesis of viral pathogens of humans. [unreadable] [unreadable] [unreadable]..