H Jiang

Summary

Affiliation: University of Missouri
Country: USA

Publications

  1. ncbi request reprint Involvement of hepatocyte nuclear factor-4 in the expression of the growth hormone receptor 1A messenger ribonucleic acid in bovine liver
    H Jiang
    Animal Sciences Research Center, Department of Animal Sciences, University of Missouri, Columbia, MO 65211, USA
    Mol Endocrinol 15:1023-34. 2001
  2. doi request reprint A miniature condition in Brahman cattle is associated with a single nucleotide mutation within the growth hormone gene
    B L McCormack
    University of Missouri, Columbia, MO 65211, USA
    Domest Anim Endocrinol 37:104-11. 2009
  3. ncbi request reprint Variants of the 5'-untranslated region of the bovine growth hormone receptor mRNA: isolation, expression and effects on translational efficiency
    H Jiang
    Department of Animal Sciences, 164 Animal Science Research Center, University of Missouri, 65211 5300, Columbia MO, USA
    Gene 265:45-53. 2001
  4. ncbi request reprint Isolation and characterization of a novel promoter for the bovine growth hormone receptor gene
    H Jiang
    Department of Animal Sciences, University of Missouri, Columbia, Missouri 65211, USA
    J Biol Chem 274:7893-900. 1999
  5. ncbi request reprint cDNA sequence and expression of bovine prodynorphin
    H Jiang
    Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA
    Gene 186:279-83. 1997
  6. ncbi request reprint Human T-lymphotropic virus type I Tax protein utilizes distinct pathways for p53 inhibition that are cell type-dependent
    C A Pise-Masison
    Basic Research Laboratory, Virus Tumor Biology Section, NCI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 276:200-5. 2001
  7. ncbi request reprint The Wilms' tumor gene product WT1 mediates the down-regulation of the rat epidermal growth factor receptor by nerve growth factor in PC12 cells
    X W Liu
    Section on Growth Factors and Laboratory of Developmental and Molecular Immunity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    J Biol Chem 276:5068-73. 2001
  8. ncbi request reprint Expression of growth hormone receptor 1A mRNA is decreased in dairy cows but not in beef cows at parturition
    H Jiang
    Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg 24061, USA
    J Dairy Sci 88:1370-7. 2005
  9. ncbi request reprint Trait-associated sequence variation in the bovine growth hormone receptor 1A promoter does not affect promoter activity in vitro
    Y Zhou
    Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 0306, USA
    Anim Genet 36:156-9. 2005
  10. ncbi request reprint Growth hormone regulates the expression of hepatocyte nuclear factor-3 gamma and other liver-enriched transcription factors in the bovine liver
    S Eleswarapu
    Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
    J Endocrinol 184:95-105. 2005

Collaborators

Detail Information

Publications63

  1. ncbi request reprint Involvement of hepatocyte nuclear factor-4 in the expression of the growth hormone receptor 1A messenger ribonucleic acid in bovine liver
    H Jiang
    Animal Sciences Research Center, Department of Animal Sciences, University of Missouri, Columbia, MO 65211, USA
    Mol Endocrinol 15:1023-34. 2001
    ..Collectively, these observations suggest that the liver-enriched transcription factor HNF-4 plays a role in the expression of GHR 1A mRNA in bovine liver...
  2. doi request reprint A miniature condition in Brahman cattle is associated with a single nucleotide mutation within the growth hormone gene
    B L McCormack
    University of Missouri, Columbia, MO 65211, USA
    Domest Anim Endocrinol 37:104-11. 2009
    ..Cattle of normal size had at least 1 copy of the normal GH allele. Threonine 200 in bovine GH is required for normal growth in cattle...
  3. ncbi request reprint Variants of the 5'-untranslated region of the bovine growth hormone receptor mRNA: isolation, expression and effects on translational efficiency
    H Jiang
    Department of Animal Sciences, 164 Animal Science Research Center, University of Missouri, 65211 5300, Columbia MO, USA
    Gene 265:45-53. 2001
    ..The observations in the present study suggest that GHR expression in the bovine may be controlled by translational mechanisms in addition to complex transcriptional mechanisms...
  4. ncbi request reprint Isolation and characterization of a novel promoter for the bovine growth hormone receptor gene
    H Jiang
    Department of Animal Sciences, University of Missouri, Columbia, Missouri 65211, USA
    J Biol Chem 274:7893-900. 1999
    ..In transfected cells, the P2 promoter served as an enhancer for the P3 promoter. Existence and co-regulation of two ubiquitous promoters may be a mechanism for achieving a high level of expression of the GHR gene in multiple tissues...
  5. ncbi request reprint cDNA sequence and expression of bovine prodynorphin
    H Jiang
    Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA
    Gene 186:279-83. 1997
    ....
  6. ncbi request reprint Human T-lymphotropic virus type I Tax protein utilizes distinct pathways for p53 inhibition that are cell type-dependent
    C A Pise-Masison
    Basic Research Laboratory, Virus Tumor Biology Section, NCI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 276:200-5. 2001
    ..Thus our data suggests that Tax utilizes distinct mechanisms to inhibit p53 function that are cell type-dependent...
  7. ncbi request reprint The Wilms' tumor gene product WT1 mediates the down-regulation of the rat epidermal growth factor receptor by nerve growth factor in PC12 cells
    X W Liu
    Section on Growth Factors and Laboratory of Developmental and Molecular Immunity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    J Biol Chem 276:5068-73. 2001
    ..These results indicate that NGF-induced down-regulation of the EGFR in PC12 cells is mediated through WT1 and that WT1 may play an important role in the differentiation of nerve cells...
  8. ncbi request reprint Expression of growth hormone receptor 1A mRNA is decreased in dairy cows but not in beef cows at parturition
    H Jiang
    Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg 24061, USA
    J Dairy Sci 88:1370-7. 2005
    ....
  9. ncbi request reprint Trait-associated sequence variation in the bovine growth hormone receptor 1A promoter does not affect promoter activity in vitro
    Y Zhou
    Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 0306, USA
    Anim Genet 36:156-9. 2005
    ....
  10. ncbi request reprint Growth hormone regulates the expression of hepatocyte nuclear factor-3 gamma and other liver-enriched transcription factors in the bovine liver
    S Eleswarapu
    Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
    J Endocrinol 184:95-105. 2005
    ....
  11. pmc The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia
    H Jiang
    Department of Zoology and Genetics, Iowa State University, Ames, IA 50011 3260
    Proc Natl Acad Sci U S A 98:7916-21. 2001
    ..Additionally, we find that nuclear localization of AHA-1 is disrupted in an hif-1 mutant. This finding suggests that heterodimerization may be a prerequisite for efficient nuclear translocation of AHA-1...
  12. ncbi request reprint Chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) and hepatocyte nuclear factor 4gamma (HNF-4gamma) and HNF-4alpha regulate the bovine growth hormone receptor 1A promoter through a common DNA element
    Q Xu
    Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, USA
    J Mol Endocrinol 32:947-61. 2004
    ..These results together identify COUP-TFII, HNF-4gamma and HNF-4alpha as transcription factors regulating GHR 1A promoter activity through binding to a common DNA element...
  13. ncbi request reprint Cloning and characterization of the bovine class 1 and class 2 insulin-like growth factor-I mRNAs
    Y Wang
    Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA
    Domest Anim Endocrinol 25:315-28. 2003
    ..05). These results indicate that the IGF-I gene in cattle is transcribed as class 1 and class 2 IGF-I mRNAs and that the two classes of IGF-I mRNAs may be regulated differentially at both transcriptional and translational levels...
  14. ncbi request reprint Polymorphic karyotypes and sex chromosomes in the tufted deer (Elaphodus cephalophus): cytogenetic studies and analyses of sex chromosome-linked genes
    X Cao
    Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, P R of China
    Cytogenet Genome Res 109:512-8. 2005
    ..The increased size of both, the X and Y chromosome, appears to be at least partially attributable to the presence of substantial amounts of heterochromatin...
  15. ncbi request reprint Short communication: A milk trait-associated polymorphism in the bovine growth hormone receptor gene does not affect receptor signaling
    Y Zhou
    Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg 24061, USA
    J Dairy Sci 89:1761-4. 2006
    ....
  16. ncbi request reprint [A study on the mechanism of the biological roles of danshensu on fibroblast]
    H Jiang
    Department of Burns and Plastic Surgery, Nanjing Army General Hospital, Nanjing, 210002 P. R. China
    Zhonghua Shao Shang Za Zhi 17:36-8. 2001
    ..Furthermore, danshensu could also inhibit the nuclear transcription factor NF-1 activity of fibroblast and modulate the synthesis and secretion of collagen...
  17. ncbi request reprint Selective G protein coupling by C-C chemokine receptors
    Y Kuang
    Department of Pharmacology, University of Rochester, Rochester, New York 14642, USA
    J Biol Chem 271:3975-8. 1996
    ..The commonality of the chemokine receptors in coupling to the Gi-Gbetagamma-PLC beta2 pathway provides a potential target for developing broad spectrum anti-inflammatory drugs...
  18. ncbi request reprint Growth hormone can induce expression of four major milk protein genes in transfected MAC-T cells
    Y Zhou
    Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, 24061, USA
    J Dairy Sci 91:100-8. 2008
    ....
  19. ncbi request reprint Organization, sequence, and expression of the murine S100 beta gene. Transcriptional regulation by cell type-specific cis-acting regulatory elements
    H Jiang
    Department of Neurology, University of Maryland School of Medicine, Baltimore
    J Biol Chem 268:20502-11. 1993
    ..The murine S100 beta gene is under complex transcriptional regulation involving tonic negative control exerted by combination of multiple cis-acting regulatory elements including cell type-specific elements...
  20. ncbi request reprint Human catechol-O-methyltransferase down-regulation by estradiol
    H Jiang
    Division of Neurology, University Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, PR China
    Neuropharmacology 45:1011-8. 2003
    ..Our findings may explain the lower of COMT activity in women compared to that in men, and, in part, the beneficial effects of E2 therapy in post-menopausal Parkinson's disease patients...
  21. ncbi request reprint Interactions between the ovary and the local IGF-I axis modulate mammary development in prepubertal heifers
    S D K Berry
    Department of Dairy Science, Virginia Tech, Blacksburg, Virginia 24061 0315, USA
    J Endocrinol 177:295-304. 2003
    ..Overall, the data suggested that interactions between the ovary and the local IGF-I axis act to optimize the availability and effectiveness of IGF-I within the gland to stimulate mammary growth...
  22. ncbi request reprint [Ki-67 antisense therapy in murine renal cell carcinoma models]
    I Kausch
    Klinik und Poliklinik fur Urologie, Universitatsklinikum Schleswig Holstein, Campus Lubeck
    Aktuelle Urol 36:142-8. 2005
    ..We intended to evaluate the effects of this therapeutic concept in two renal cell carcinoma (RCC) models...
  23. ncbi request reprint [Effects of zinc deficiency on the distribution of elements in the tissue of pregnant rats and their fetuses]
    C Zhao
    School of Public Health, Shandong Medical University, Jinan 250012, China
    Wei Sheng Yan Jiu 30:277-9. 2001
    ..There may be a competitive mechanism on the transportation of Zn and Fe in the placenta of rats. In brief, the distribution of minerals in maternal tissues induced by zinc deficiency might be different from those in fetuses...
  24. ncbi request reprint Implantation of BM cells transfected with phVEGF165 enhances functional improvement of the infarcted heart
    H X Xu
    Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, People s Republic of China
    Cytotherapy 6:204-11. 2004
    ....
  25. ncbi request reprint Gene expression profiling of acute rejection and mixed lymphocyte reaction with tacrolimus immunosuppression
    L Erickson
    Fujisawa Research Institute of America, Northwestern University Evanston Research Park, 1801 Maple Avenue, Evanston, IL 60201, USA
    Transplant Proc 34:1385-6. 2002
  26. ncbi request reprint Scd1ab-Xyk: a new asebia allele characterized by a CCC trinucleotide insertion in exon 5 of the stearoyl-CoA desaturase 1 gene in mouse
    Y Lu
    Health Science Center, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Second Medical University, 200025, Shanghai, People s Republic of China
    Mol Genet Genomics 272:129-37. 2004
    ..This new mouse mutant is a good model not only for the study of scarring alopecias in humans, which are characterized by hypoplasic sebaceous glands, but also for studying the structure and function of the Scd1 protein...
  27. pmc Constitutively active Rheb induces oncogenic transformation
    H Jiang
    1Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA
    Oncogene 27:5729-40. 2008
    ..An engineered N-terminal myristylation signal can substitute for the farnesylation. Immunofluorescence localizes wild-type and mutant Rheb to vesicular structures in the cytoplasm, overlapping with the endoplasmic reticulum...
  28. pmc Gene structure and expression profile of Manduca sexta prophenoloxidase-activating proteinase-3 (PAP-3), an immune protein containing two clip domains
    Z Zou
    Department of Entomology and Plant Pathology, Oklahoma State University, Stillwater, 74078, USA
    Insect Mol Biol 14:433-42. 2005
    ..The mRNA level is high in the epithelium, fat body and haemocytes. Tissue-specific alternative splicing occurs in the fat body and trachea. A bacterial injection markedly induced the gene expression in the fat body and haemocytes...
  29. ncbi request reprint Taurine protects against ischemia-reperfusion injury in rabbit livers
    L Tong
    Hepatosplenic Surgery Center of Heilongjiang Province, The First Clinical College of Harbin Medical University, and Department of General Surgery, Shandong Provincial Qianfoshan Hospital, China
    Transplant Proc 38:1575-9. 2006
    ..These results suggest that taurine is a potent useful reagent to protect the rabbit liver from ischemia-reperfusion injury...
  30. ncbi request reprint Genetic engineering of Periplaneta fuliginosa densovirus as an improved biopesticide
    H Jiang
    State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China
    Arch Virol 152:383-94. 2007
    ..fuliginosa nymphs approximate 32% faster than wt PfDNV only. This is the first report showing the improvement of engineered densovirus for the potential application of biopesticide...
  31. ncbi request reprint Antisense integrin alphaV and beta3 gene therapy suppresses subcutaneously implanted hepatocellular carcinomas
    J Li
    Department of General Surgery, Shandong Provincial Qianfoshan Hospital, Jinan, China
    Dig Liver Dis 39:557-65. 2007
    ..Integrin alphaVbeta3 plays a critical role in tumour angiogenesis and metastasis formation, and is recognized as a key therapeutic target in the treatment of cancer...
  32. ncbi request reprint Confirmation of four nitroimidazoles in porcine liver by liquid chromatography-tandem mass spectrometry
    X Xia
    China Agricultural University, College of Veterinary Medicine, Department of Pharmacology and Toxicology, Beijing 100094, China
    Anal Chim Acta 586:394-8. 2007
    ..The limits of confirmation were 0.1-0.5 microg kg(-1) for the analytes...
  33. ncbi request reprint Plasticity of ovarian cancer cell SKOV3ip and vasculogenic mimicry in vivo
    M Su
    Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, P R China
    Int J Gynecol Cancer 18:476-86. 2008
    ..HIF-1alpha protein expression correlated with CD31 and Factor VIII protein expression in SKOV3ip. These results indicated that VM might be associated with HIF-1alpha...
  34. doi request reprint Evidence of local evolution of tomato-infecting begomovirus species in West Africa: characterization of tomato leaf curl Mali virus and tomato yellow leaf crumple virus from Mali
    Y C Zhou
    Department of Plant Pathology, University of California Davis, Davis, CA 95616, USA
    Arch Virol 153:693-706. 2008
    ..Virus-specific PCR primers were developed for detection of ToLCMLV and ToYLCrV and will be used to further investigate the distribution and host range of these viruses...
  35. doi request reprint The JNK/AP1/ATF2 pathway is involved in H2O2-induced acetylcholinesterase expression during apoptosis
    J Y Zhang
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China
    Cell Mol Life Sci 65:1435-45. 2008
    ..The AP1-like element binds to the transcription factors, c-jun and ATF2, while the ATF2 element binds mainly ATF2. Taken together, our results strongly suggest that H2O2 induces AChE expression via the JNK/AP1/ ATF2 signaling pathway...
  36. ncbi request reprint [Analysis of the parkin gene deletion mutations in Chinese patients with Parkinson's disease]
    B Tang
    Department of Neurology, Xiangya Hospital, Zhongnan University, Changsha 410008, China
    Zhonghua Nei Ke Za Zhi 40:799-801. 2001
    ..In addition, deletion mutations of parkin gene at exons 3, 4 and 6, were not found. CONCLUSION: There are deletion mutations of parkin gene at exons 5 and 7 in Chinese PD patients...
  37. ncbi request reprint A double cysteine trkA mutant exhibiting reduced NGF binding and delayed Erk signaling
    H Jiang
    William T Gossett Neurology Laboratories, Henry Ford Health Sciences Center, Detroit, MI 48202, USA
    J Mol Neurosci 17:293-302. 2001
    ..Cumulatively, our findings support a model in which Cys436 of the trkA is responsible for the rapid transfer of the transmembrane occupancy signal to the SHC adaptor protein for activation of the Ras-Erk pathway and DNA synthesis...
  38. ncbi request reprint Localization of EMSP1 expression during tooth formation and cloning of mouse cDNA
    J C Hu
    University of Texas Health Science Center at San Antonio, School of Dentistry, Department of Pediatric Dentistry, 78284 7888, USA
    J Dent Res 79:70-6. 2000
    ..We conclude that EMSP1 is expressed by pig and mouse ameloblasts during the early maturation stage of amelogenesis...
  39. pmc Analysis of the mechanism by which glucose inhibits maltose induction of MAL gene expression in Saccharomyces
    Z Hu
    Department of Biochemistry, Queens College and Graduate School of CUNY, Flushing, New York 11367, USA
    Genetics 154:121-32. 2000
    ..Evidence is presented indicating that, in addition to its role in the inactivation of Mig1p, Snf1p is required post-transcriptionally for the synthesis of maltose permease whose function is essential for maltose induction...
  40. ncbi request reprint Mutation analysis of hereditary multiple exostoses in the Chinese
    L Xu
    National Laboratory of Medical Genetics, Hunan Medical University, Changsha, PR China
    Hum Genet 105:45-50. 1999
    ..Our findings suggest a possibly different genetic spectrum of this disease in different populations...
  41. ncbi request reprint Complete coding sequence of inducible nitric oxide synthase from human heart and skeletal muscle of patients with chronic heart failure
    V Adams
    Heart Center GmbH, Division of Cardiology, University of Leipzig, Germany
    Nitric Oxide 2:242-9. 1998
    ..The iNOS sequence described in this report is the first one isolated directly from human tissue expressing iNOS in the circumstances of chronic heart failure...
  42. ncbi request reprint Melanoma differentiation associated gene-9, mda-9, is a human gamma interferon responsive gene
    J J Lin
    Department of Pathology, Herbert Irving Comprehensive Cancer Center, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Gene 207:105-10. 1998
    ....
  43. ncbi request reprint Evidence for the presence of the platelet-activating factor receptor in the CFW mouse preimplantation two-cell-stage embryo
    W E Roudebush
    Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston 29425, USA
    Biol Reprod 57:575-9. 1997
    ..PAF treatment of the two-cell-stage CFW mouse embryo resulted in a fourfold increase in intracellular calcium over background levels...
  44. ncbi request reprint Sequence and expression of mouse proteasome activator PA28 and the related autoantigen Ki
    H Jiang
    Graduate Program in Cell Biology, Department of Cell Biology, Neurobiology, and Anatomy, University of Cincinnati, 231 Bethesda Avenue, Cincinnati, OH 45 267 0521, USA
    Immunogenetics 46:93-8. 1997
    ..Southern blot analysis suggests that both PA28a and PA28b are multiple-copy genes, while Ki is a single-copy gene...
  45. ncbi request reprint Selective coupling of beta 2-adrenergic receptor to hematopoietic-specific G proteins
    D Wu
    Department of Pharmacology, University of Rochester Medical Center, New York 14642, USA
    J Biol Chem 270:16008-10. 1995
    ..Thus, we conclude that the beta 2-adrenergic receptor can specifically couple to G alpha 15 and G alpha 16, but not to G alpha q, G alpha 11, or G alpha 14 to activate PLC...
  46. ncbi request reprint Suppression of human ribosomal protein L23A expression during cell growth inhibition by interferon-beta
    H Jiang
    Department of Pathology, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Oncogene 14:473-80. 1997
    ..These results suggest that rp L23a may be one of the target molecules involved in mediating growth inhibition by interferon...
  47. ncbi request reprint Direct association between the yeast Rad51 and Rad54 recombination proteins
    H Jiang
    Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712, USA
    J Biol Chem 271:33181-6. 1996
    ..Combined with previously reported results, these data imply that the Rad54 protein is part of a multiprotein yeast recombination complex...
  48. pmc The melanoma differentiation associated gene mda-7 suppresses cancer cell growth
    H Jiang
    Department of Pathology, Columbia Presbyterian Cancer Center, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 93:9160-5. 1996
    ....
  49. ncbi request reprint Cloning and characterization of the promoter region of the rat epidermal growth factor receptor gene and its transcriptional regulation by nerve growth factor in PC12 cells
    X W Liu
    Section on Growth Factors, NICHD, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 275:7280-8. 2000
    ..Our results demonstrate that TCC repeat sequences are required for the down-regulation of rat EGFR by NGF in PC12 cells and may lead to the identification of the NGF-responsive transcription factors...
  50. ncbi request reprint Cloning human enamelin cDNA, chromosomal localization, and analysis of expression during tooth development
    C C Hu
    University of Texas Health Science Center at San Antonio, School of Dentistry, Department of Pediatric Dentistry, 78284 7888, USA
    J Dent Res 79:912-9. 2000
    ..These findings will facilitate the search for specific mutations in the enamelin gene in kindreds suffering from amelogenesis imperfecta...
  51. ncbi request reprint Fes mediates the IL-4 activation of insulin receptor substrate-2 and cellular proliferation
    H Jiang
    Department of Medicine and Microbiology, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    J Immunol 166:2627-34. 2001
    ..These data demonstrate that signaling pathways activated by IL-4 require different tyrosine kinases. This differential requirement predicts that specific kinase inhibitors may permit the disruption of specific IL-4-induced functions...
  52. ncbi request reprint Modified cold storage of rat livers with self-made HYD solution
    H Jiang
    Department of General Surgery, First Clinical Hospital, Harbin Medical University, Harbin 150001, China
    Chin Med J (Engl) 114:143-6. 2001
    ..05). The preservation effect on rat liver in the 30% group was the best among the modified method groups. CONCLUSION: The modified cold storage method is effective and may have potential for clinical application in liver preservation...
  53. ncbi request reprint Antisense inhibition of CD44 tailless splice variant in human articular chondrocytes promotes hyaluronan internalization
    H Jiang
    Rush University Graduate School, Chicago, IL, USA
    Arthritis Rheum 44:2599-610. 2001
    ..CONCLUSION: The expression of a natural CD44 decoy-like receptor by articular chondrocytes modulates the function of this matrix receptor...
  54. ncbi request reprint Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties
    E Y Huang
    Department of Urology, Herbert Irving Comprehensive Cancer Center, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Oncogene 20:7051-63. 2001
    ..Mda-7 represents a differentiation, growth and apoptosis associated gene with potential utility for the gene-based therapy of diverse human cancers...
  55. ncbi request reprint Expression and purification of Manduca sexta prophenoloxidase-activating proteinase precursor (proPAP) from baculovirus-infected insect cells
    Y Wang
    Departmant of Entomology and Plant Pathology, Oklahoma State University, Stillwater, Oklahoma 74078, USA
    Protein Expr Purif 23:328-37. 2001
    ..After the purified proPAP was added to the larval hemolymph, it was readily activated by an unknown proteinase in the presence of M. lysodeikticus...
  56. pmc The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis
    T Kume
    Howard Hughes Medical Institute and Department of Cell Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Genes Dev 15:2470-82. 2001
    ..We propose that the two genes interact with the Notch signaling pathway and are required for the prepatterning of anterior and posterior domains in the presumptive somites through a putative Notch/Delta/Mesp regulatory loop...
  57. ncbi request reprint A novel gene causing a mendelian audiogenic mouse epilepsy
    S L Skradski
    Department of Pharmacology and Toxicology, University of Utah, Salt Lake City 84112, USA
    Neuron 31:537-44. 2001
    ..Study of the MASS1 protein will lead to new insights into regulation of neuronal excitability and a new pathway through which dysfunction can lead to epilepsy...
  58. ncbi request reprint A bacteria-induced, intracellular serpin in granular hemocytes of Manduca sexta
    H Gan
    Department of Biochemistry, Kansas State University, Manhattan, KS 66506, USA
    Insect Biochem Mol Biol 31:887-98. 2001
    ..The intracellular location of serpin-2 suggests a function for serpin-2 different from the plasma serpin-1 proteins...
  59. ncbi request reprint 3D-QSAR model of flavonoids binding at benzodiazepine site in GABAA receptors
    X Huang
    Center for Drug Discovery and Design, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 294 Taiyuan Road, Shanghai 200031, P. R. China
    J Med Chem 44:1883-91. 2001
    ..The different binding affinities could be explained according to the frontier orbitals and electrostatic potential (ESP) maps. The ESP could be used as a novel starting point for designing more selective BZ-binding-site ligands...
  60. ncbi request reprint Cloning of differentially expressed genes in an HIV-1 resistant T cell clone by rapid subtraction hybridization, RaSH
    M Simm
    Molecular Virology Laboratory, St. Luke's-Roosevelt Hospital Center, Columbia University, New York, NY 10019, USA
    Gene 269:93-101. 2001
    ..Analysis of the pattern of expression of the differentially expressed genes documented eleven genes with enhanced (HR clones) and six genes with reduced (HS clones) expression in HIV-1 resistant versus HIV-1 susceptible T-cell clones...
  61. ncbi request reprint Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol RaSH
    D Kang
    Department of Urology, Herbert Irving Comprehensive Cancer Center, Columbia University, College of Physicians and Surgeons, BB 15 1501, 630 West 168th Street, New York, NY 10032, USA
    Gene 267:233-42. 2001
    ..This gene may contribute to the phenotypic changes induced by IFN-beta during growth arrest and differentiation in human melanoma cells and other cell types as well as the antiviral and growth inhibitory effects of interferon...
  62. pmc Brownian dynamics simulations of interaction between scorpion toxin Lq2 and potassium ion channel
    M Cui
    Center for Drug Discovery and Design, State Key Laboratory of New Drug Research, Shanghai Institute of Meteria Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, Peoples Republic of China
    Biophys J 80:1659-69. 2001
    ....
  63. ncbi request reprint Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression
    H Jiang
    Department of Pathology, Columbia Presbyterian Cancer Center, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Oncogene 11:2477-86. 1995
    ..The mda-7 gene may also function as a negative regulator of melanoma progression...