Suma Jacob

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. pmc Autism spectrum and obsessive-compulsive disorders: OC behaviors, phenotypes and genetics
    Suma Jacob
    Department of Psychiatry, University of Illinois School, Chicago, Illinois 60612, USA
    Autism Res 2:293-311. 2009
  2. pmc A quantitative association study of SLC25A12 and restricted repetitive behavior traits in autism spectrum disorders
    Soo Jeong Kim
    Department of Psychiatry, University of Florida, Gainesville, FL, USA
    Mol Autism 2:8. 2011
  3. pmc Association of the oxytocin receptor gene (OXTR) in Caucasian children and adolescents with autism
    Suma Jacob
    Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, 1747 West Roosevelt Road, Chicago, IL 60608, USA
    Neurosci Lett 417:6-9. 2007
  4. pmc Escitalopram pharmacogenetics: CYP2C19 relationships with dosing and clinical outcomes in autism spectrum disorder
    Jeffrey R Bishop
    aDepartment of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy bDepartment of Psychiatry, University of Minnesota College of Medicine, Minneapolis, Minnesota cDepartment of Psychiatry, University of Illinois at Chicago College of Medicine, Chicago, Illinois dDepartments of Psychiatry and Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Pharmacogenet Genomics 25:548-54. 2015
  5. pmc Variants in Adjacent Oxytocin/Vasopressin Gene Region and Associations with ASD Diagnosis and Other Autism Related Endophenotypes
    Sunday M Francis
    Department of Psychiatry, University of Minnesota Minneapolis, MN, USA
    Front Neurosci 10:195. 2016
  6. doi request reprint Urinary and plasma oxytocin changes in response to MDMA or intranasal oxytocin administration
    Sunday M Francis
    Institute of Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, 1747 West Roosevelt Road, Chicago, IL 60608, USA Electronic address
    Psychoneuroendocrinology 74:92-100. 2016
  7. pmc Parental broader autism subphenotypes in ASD affected families: relationship to gender, child's symptoms, SSRI treatment, and platelet serotonin
    Tal Levin-Decanini
    Department of Psychiatry, University of Illinois, Chicago, Illinois, USA
    Autism Res 6:621-30. 2013
  8. pmc ASD and Genetic Associations with Receptors for Oxytocin and Vasopressin-AVPR1A, AVPR1B, and OXTR
    Sunday M Francis
    Department of Psychiatry, University of Minnesota Minneapolis, MN, USA
    Front Neurosci 10:516. 2016
  9. pmc Pharmacogenetic Study of Serotonin Transporter and 5HT2A Genotypes in Autism
    Fedra Najjar
    1 Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois
    J Child Adolesc Psychopharmacol 25:467-74. 2015
  10. pmc Preliminary evidence for the interaction of the oxytocin receptor gene (oxtr) and face processing in differentiating prenatal smoking patterns
    Suena H Massey
    Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Suite 1000, Chicago, IL, USA Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 633 North Saint Clair Street, 19th Floor, Chicago, IL, USA Electronic address
    Neurosci Lett 584:259-64. 2015

Collaborators

Detail Information

Publications11

  1. pmc Autism spectrum and obsessive-compulsive disorders: OC behaviors, phenotypes and genetics
    Suma Jacob
    Department of Psychiatry, University of Illinois School, Chicago, Illinois 60612, USA
    Autism Res 2:293-311. 2009
    ..There is a growing need to identify the range of molecular pathways involved in OCB related to ASD in order to develop novel treatment interventions...
  2. pmc A quantitative association study of SLC25A12 and restricted repetitive behavior traits in autism spectrum disorders
    Soo Jeong Kim
    Department of Psychiatry, University of Florida, Gainesville, FL, USA
    Mol Autism 2:8. 2011
    ....
  3. pmc Association of the oxytocin receptor gene (OXTR) in Caucasian children and adolescents with autism
    Suma Jacob
    Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, 1747 West Roosevelt Road, Chicago, IL 60608, USA
    Neurosci Lett 417:6-9. 2007
    ..Overtransmission of different alleles in different populations may be due to a different pattern of linkage disequilibrium between the marker rs2254298 and an as yet undetermined susceptibility variant in OXTR...
  4. pmc Escitalopram pharmacogenetics: CYP2C19 relationships with dosing and clinical outcomes in autism spectrum disorder
    Jeffrey R Bishop
    aDepartment of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy bDepartment of Psychiatry, University of Minnesota College of Medicine, Minneapolis, Minnesota cDepartment of Psychiatry, University of Illinois at Chicago College of Medicine, Chicago, Illinois dDepartments of Psychiatry and Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Pharmacogenet Genomics 25:548-54. 2015
    ..CYP2C19 encodes the primary enzyme responsible for escitalopram metabolism and we investigated whether polymorphisms in CYP2C19 were related to symptoms and dosing in a pharmacogenetic study of ASD...
  5. pmc Variants in Adjacent Oxytocin/Vasopressin Gene Region and Associations with ASD Diagnosis and Other Autism Related Endophenotypes
    Sunday M Francis
    Department of Psychiatry, University of Minnesota Minneapolis, MN, USA
    Front Neurosci 10:195. 2016
    ..Since most studies have focused on the receptors in the OT-AVP system, we investigated genetic variation within peptide genes for association with phenotypic ASD features that help identify subgroups within the spectrum...
  6. doi request reprint Urinary and plasma oxytocin changes in response to MDMA or intranasal oxytocin administration
    Sunday M Francis
    Institute of Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, 1747 West Roosevelt Road, Chicago, IL 60608, USA Electronic address
    Psychoneuroendocrinology 74:92-100. 2016
    ..Here, we conducted two within-subjects, double-blind studies exploring changes in uOT and pOT levels following administration of two drugs: MDMA, an oxytocin-releasing drug (Study 1), and intranasal oxytocin (INOT: Study 1 and 2)...
  7. pmc Parental broader autism subphenotypes in ASD affected families: relationship to gender, child's symptoms, SSRI treatment, and platelet serotonin
    Tal Levin-Decanini
    Department of Psychiatry, University of Illinois, Chicago, Illinois, USA
    Autism Res 6:621-30. 2013
    ..Study results suggest that the expression of the BAP varies not only across parental gender, but also across individuals using psychotropic medication and those who do not...
  8. pmc ASD and Genetic Associations with Receptors for Oxytocin and Vasopressin-AVPR1A, AVPR1B, and OXTR
    Sunday M Francis
    Department of Psychiatry, University of Minnesota Minneapolis, MN, USA
    Front Neurosci 10:516. 2016
    ..We reported a novel association with ASD and AVPR1B SNPs. Understanding of genotype-phenotype relationships may be helpful in the development of pharmacological interventions for the OT/AVP system...
  9. pmc Pharmacogenetic Study of Serotonin Transporter and 5HT2A Genotypes in Autism
    Fedra Najjar
    1 Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois
    J Child Adolesc Psychopharmacol 25:467-74. 2015
    ..The purpose of this study was to determine whether polymorphisms in the serotonin transporter (SLC6A4) and serotonin-2A receptor (HTR2A) genes are associated with response to escitalopram in patients with autism spectrum disorder (ASD)...
  10. pmc Preliminary evidence for the interaction of the oxytocin receptor gene (oxtr) and face processing in differentiating prenatal smoking patterns
    Suena H Massey
    Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Suite 1000, Chicago, IL, USA Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, 633 North Saint Clair Street, 19th Floor, Chicago, IL, USA Electronic address
    Neurosci Lett 584:259-64. 2015
    ..892). Testing this "empathy hypothesis of prenatal smoking cessation" in larger studies designed to examine this question can elucidate whether interventions to enhance empathy can improve prenatal smoking cessation rates...
  11. pmc Plasma oxytocin concentrations following MDMA or intranasal oxytocin in humans
    Matthew G Kirkpatrick
    Department of Psychiatry and Behavioral Neurosciences, University of Chicago, Chicago, IL, USA
    Psychoneuroendocrinology 46:23-31. 2014
    ..Future studies examining the effects of oxytocin antagonists on responses to MDMA will help to determine the mechanism by which MDMA produces pro-social effects. ..