Richard G Hunter
Affiliation: University of Massachusetts
- Stress and corticosteroids regulate rat hippocampal mitochondrial DNA gene expression via the glucocorticoid receptorRichard G Hunter
Department of Psychology, University of Massachusetts, Boston, MA 02125 Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10065
Proc Natl Acad Sci U S A 113:9099-104. 2016..These findings demonstrate GR and stress-dependent transcriptional regulation of the mitochondrial genome in vivo and are consistent with previous work linking stress and GCs with changes in the function of brain mitochondria. ..
- Stress and anxiety across the lifespan: structural plasticity and epigenetic regulationRichard G Hunter
Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, 1230 York Ave, New York, NY 10065, USA
Epigenomics 5:177-94. 2013....
- Acute stress and hippocampal histone H3 lysine 9 trimethylation, a retrotransposon silencing responseRichard G Hunter
Laboratory of Neurobiology and Behavior, Laboratory of Neuroendocrinology, and Genomics Resource Center, The Rockefeller University, New York, NY 10065, USA
Proc Natl Acad Sci U S A 109:17657-62. 2012..These results are a unique demonstration of the regulatory effect of environmental stress, via an epigenetic mark, on the vast genomic terra incognita represented by transposable elements...
- Regulation of the nicotinic receptor alpha7 subunit by chronic stress and corticosteroidsRichard G Hunter
Laboratory of Neuroendocrinology, Rockefeller University, New York, New York 10065, USA
Brain Res 1325:141-6. 2010..While the mechanism behind these observations is as yet unclear, they may be neuroprotective against the damaging effects of CRS or an example of adaptation to the allostatic load produced by CRS...
- Regulation of hippocampal H3 histone methylation by acute and chronic stressRichard G Hunter
Laboratory of Neuroendocrinology, Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Proc Natl Acad Sci U S A 106:20912-7. 2009....
- The dynamic genome: transposons and environmental adaptation in the nervous systemHannah E Lapp
Department of Psychology and Developmental Brain Sciences Program, University of Massachusetts Boston, Boston, MA 02125 3393, USA
Epigenomics 8:237-49. 2016..The regulation of TE expression by steroid, epigenetic and other mechanisms in interplay with the environment represents a significant and novel avenue to understanding both normal brain function and disease. ..
- Stress and anxiety: structural plasticity and epigenetic regulation as a consequence of stressBruce S McEwen
Laboratory of Neuroendocrinology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Neuropharmacology 62:3-12. 2012..Finally, we suggest that such an approach needs to be extended to other brain areas that are also involved in anxiety and mood. This article is part of a Special Issue entitled 'Anxiety and Depression'...
- Stress and the dynamic genome: Steroids, epigenetics, and the transposomeRichard G Hunter
Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY Developmental and Brain Sciences Program, Department of Psychology, University of Massachusetts, Boston, MA 02125 and
Proc Natl Acad Sci U S A 112:6828-33. 2015..These observations also raise the possibility that the transposome might have adaptive functions at the level of both evolution and the individual organism. ..
- Regulation of kainate receptor subunit mRNA by stress and corticosteroids in the rat hippocampusRichard G Hunter
Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York, United States of America
PLoS ONE 4:e4328. 2009....
- Hippocampal kainate receptorsErik B Bloss
Fishberg Department of Neuroscience and Kastor Neurobiology of Aging Laboratory, Mount Sinai School of Medicine, New York, New York, USA
Vitam Horm 82:167-84. 2010....
- Mechanisms of stress in the brainBruce S McEwen
Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York, USA
Nat Neurosci 18:1353-63. 2015..Elucidation of the underlying mechanisms of plasticity and vulnerability of the brain provides a basis for understanding the efficacy of interventions for anxiety and depressive disorders as well as age-related cognitive decline. ..