- GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behaviorRobert F Hunt
Epilepsy Research Laboratory, University of California, San Francisco, California, USA
Nat Neurosci 16:692-7. 2013..Our results highlight a critical role for interneurons in epilepsy and suggest that interneuron cell transplantation is a powerful approach to halting seizures and rescuing accompanying deficits in severely epileptic mice...
- LIS1 deficiency promotes dysfunctional synaptic integration of granule cells generated in the developing and adult dentate gyrusRobert F Hunt
Epilepsy Research Laboratory, Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
J Neurosci 32:12862-75. 2012....
- 14-3-3ε and ζ regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brainKazuhito Toyo-oka
Department of Pediatrics and Institute for Human Genetics, University of California, San Francisco School of Medicine, San Francisco, California 94143, Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, Pennsylvania 19129
J Neurosci 34:12168-81. 2014..Our findings provide new evidence that 14-3-3 proteins play important roles in neurogenesis and neuronal migration via the regulation of distinct signaling cascades. ..
- A novel zebrafish model of hyperthermia-induced seizures reveals a role for TRPV4 channels and NMDA-type glutamate receptorsRobert F Hunt
Epilepsy Research Laboratory, Department of Neurological Surgery, Biomedical Graduate Program, University of California San Francisco, San Francisco, CA 94143, USA
Exp Neurol 237:199-206. 2012..Taken together, our findings suggest a role of heat-activation of TRPV4 channels and enhanced NMDA receptor-mediated glutamatergic transmission in hyperthermia-induced seizures...