Mark M Banaszak Holl

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc Estrogen depletion results in nanoscale morphology changes in dermal collagen
    Ming Fang
    Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA
    J Invest Dermatol 132:1791-7. 2012
  2. doi request reprint Nanotoxicology: a personal perspective
    Mark M Banaszak Holl
    Chemistry Department, Graham Environmental Sustainability Institute, University of Michigan, Ann Arbor, MI 48109 1055, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:353-9. 2009
  3. doi request reprint The role of ganglioside GM1 in cellular internalization mechanisms of poly(amidoamine) dendrimers
    Seungpyo Hong
    Program in Macromolecular Science and Engineering and Biophysics, University of Michigan, Ann Arbor, Michigan 48109 1055, USA
    Bioconjug Chem 20:1503-13. 2009
  4. doi request reprint Synthesis, characterization, and in vitro testing of superparamagnetic iron oxide nanoparticles targeted using folic Acid-conjugated dendrimers
    Kevin J Landmark
    Programs in Applied Physics, University of Michigan, Ann Arbor, Michigan 48109, USA
    ACS Nano 2:773-83. 2008
  5. doi request reprint Wide varieties of cationic nanoparticles induce defects in supported lipid bilayers
    Pascale R Leroueil
    Department of Chemistry, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48019, USA
    Nano Lett 8:420-4. 2008
  6. doi request reprint Dendrimer-based multivalent vancomycin nanoplatform for targeting the drug-resistant bacterial surface
    Seok Ki Choi
    Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA
    ACS Nano 7:214-28. 2013
  7. pmc Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer agent
    Yuehua Zhang
    Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI 48109, USA
    Bioorg Med Chem 19:2557-64. 2011
  8. pmc Cationic poly(amidoamine) dendrimer induces lysosomal apoptotic pathway at therapeutically relevant concentrations
    Thommey P Thomas
    Department of Internal Medicine, Division of Allergy, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, 9220 MSRB III, Box 0648, Ann Arbor, Michigan 48109, USA
    Biomacromolecules 10:3207-14. 2009
  9. ncbi request reprint Lipid bilayer disruption by polycationic polymers: the roles of size and chemical functional group
    Almut Mecke
    Department of Physics, University of Michigan, Ann Arbor, 48109, USA
    Langmuir 21:10348-54. 2005
  10. pmc Polycation-induced cell membrane permeability does not enhance cellular uptake or expression efficiency of delivered DNA
    Lisa E Prevette
    Department of Chemistry, Macromolecular Science and Engineering Program, and Michigan Nanotechnology Institute for Medicine and Biological Sciences MNIMBS, University of Michigan, 911 North University Avenue, Ann Arbor, MI 48109 1055, USA
    Mol Pharm 7:870-83. 2010

Collaborators

Detail Information

Publications26

  1. pmc Estrogen depletion results in nanoscale morphology changes in dermal collagen
    Ming Fang
    Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA
    J Invest Dermatol 132:1791-7. 2012
    ..A nonparametric Kolmogorov-Smirnov test of the cumulative density function indicates a statistical difference in the sham and OVX D-spacing distributions (P<0.01)...
  2. doi request reprint Nanotoxicology: a personal perspective
    Mark M Banaszak Holl
    Chemistry Department, Graham Environmental Sustainability Institute, University of Michigan, Ann Arbor, MI 48109 1055, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:353-9. 2009
    ..The use of nanoparticles to provide enhanced delivery of chemotherapeutics is presented followed by a discussion of the size-based effects of electron transfer and physical membrane disruption...
  3. doi request reprint The role of ganglioside GM1 in cellular internalization mechanisms of poly(amidoamine) dendrimers
    Seungpyo Hong
    Program in Macromolecular Science and Engineering and Biophysics, University of Michigan, Ann Arbor, Michigan 48109 1055, USA
    Bioconjug Chem 20:1503-13. 2009
    ..The presence of GM(1) in the membrane also had no effect upon XTT assays of cell viability or lactate dehydrogenase (LDH) assays of membrane permeability...
  4. doi request reprint Synthesis, characterization, and in vitro testing of superparamagnetic iron oxide nanoparticles targeted using folic Acid-conjugated dendrimers
    Kevin J Landmark
    Programs in Applied Physics, University of Michigan, Ann Arbor, Michigan 48109, USA
    ACS Nano 2:773-83. 2008
    ..The results were consistent between the uptake distribution quantified by flow cytometry using 6-TAMRA UV-visible fluorescence intensity and the cellular iron content determined using X-ray fluorescence microscopy...
  5. doi request reprint Wide varieties of cationic nanoparticles induce defects in supported lipid bilayers
    Pascale R Leroueil
    Department of Chemistry, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48019, USA
    Nano Lett 8:420-4. 2008
    ....
  6. doi request reprint Dendrimer-based multivalent vancomycin nanoplatform for targeting the drug-resistant bacterial surface
    Seok Ki Choi
    Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA
    ACS Nano 7:214-28. 2013
    ....
  7. pmc Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer agent
    Yuehua Zhang
    Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI 48109, USA
    Bioorg Med Chem 19:2557-64. 2011
    ..The G3-MTX induced a dose-dependent cytotoxicity in the KB cells. Therefore, the polyvalent G3-MTX may have potential as an anticancer nanodevice for the specific targeting and killing of FR-expressing tumor cells...
  8. pmc Cationic poly(amidoamine) dendrimer induces lysosomal apoptotic pathway at therapeutically relevant concentrations
    Thommey P Thomas
    Department of Internal Medicine, Division of Allergy, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, 9220 MSRB III, Box 0648, Ann Arbor, Michigan 48109, USA
    Biomacromolecules 10:3207-14. 2009
    ..These results suggest that PAMAM dendrimers are endocytosed into the KB cells through a lysosomal pathway, leading to lysosomal alkalinization and induction of mitochondria-mediated apoptosis...
  9. ncbi request reprint Lipid bilayer disruption by polycationic polymers: the roles of size and chemical functional group
    Almut Mecke
    Department of Physics, University of Michigan, Ann Arbor, 48109, USA
    Langmuir 21:10348-54. 2005
    ..These results are of general significance for understanding the physical and chemical properties of polycationic polymer interactions with membranes that lead to the transport of materials across cell membranes...
  10. pmc Polycation-induced cell membrane permeability does not enhance cellular uptake or expression efficiency of delivered DNA
    Lisa E Prevette
    Department of Chemistry, Macromolecular Science and Engineering Program, and Michigan Nanotechnology Institute for Medicine and Biological Sciences MNIMBS, University of Michigan, 911 North University Avenue, Ann Arbor, MI 48109 1055, USA
    Mol Pharm 7:870-83. 2010
    ....
  11. pmc Cationic nanoparticles induce nanoscale disruption in living cell plasma membranes
    Jiumei Chen
    Chemistry Department, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Phys Chem B 113:11179-85. 2009
    ..4 nm holes in lipid bilayers. Here, we observe data that are consistent with AMO-3 making approximately 3 nm holes in living cell membranes...
  12. doi request reprint Free energy simulation to investigate the effect of amino acid sequence environment on the severity of osteogenesis imperfecta by glycine mutations in collagen
    Kyung Hoon Lee
    Department of Chemistry, Michigan Nanotechnology Institute in Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI 48109, USA
    Biopolymers 95:401-9. 2011
    ..The presence of Gln and Arg near the mutation site, which contain large and polar side chains, provide more destabilization than amino acids containing small and nonpolar side chains...
  13. doi request reprint Type I collagen self-assembly: the roles of substrate and concentration
    Ming Fang
    Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109 1055, United States
    Langmuir 29:2330-8. 2013
    ..We then demonstrated that tilted D-spacing is uncommon in biological tissues and it does not explain previous observations of low D-spacing values in ovariectomized dermis and bone...
  14. pmc Nanoscale morphology of Type I collagen is altered in the Brtl mouse model of Osteogenesis Imperfecta
    Joseph M Wallace
    Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 1055, United States
    J Struct Biol 173:146-52. 2011
    ..Further studies are necessary to link these morphological observations to nanoscale mechanical integrity...
  15. ncbi request reprint HPLC analysis of functionalized poly(amidoamine) dendrimers and the interaction between a folate-dendrimer conjugate and folate binding protein
    Xiangyang Shi
    Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI 48109, USA
    Analyst 131:842-8. 2006
    ....
  16. pmc Synthetic and natural polycationic polymer nanoparticles interact selectively with fluid-phase domains of DMPC lipid bilayers
    Almut Mecke
    Department of Physics, The University of Michigan, Ann Arbor, Michigan 48109, USA
    Langmuir 21:8588-90. 2005
    ..We find that regions of the bilayer that are in the gel phase are unaffected by the presence of polymers, whereas the liquid phase is disrupted...
  17. doi request reprint Dual-wavelength linear regression phase unwrapping in three-dimensional microscopic images of cancer cells
    Alexander Khmaladze
    Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA
    Opt Lett 36:912-4. 2011
    ..Additionally, the limitations on the total optical height are significantly relaxed. This new methodology is widely applicable to other phase-imaging techniques as well as in applications beyond optical microscopy...
  18. ncbi request reprint Closing the gap between interdisciplinary research and disciplinary teaching
    BRIAN P COPPOLA
    Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109 1055, USA
    ACS Chem Biol 2:518-20. 2007
  19. ncbi request reprint A novel MEA/AFM platform for measurement of real-time, nanometric morphological alterations of electrically stimulated neuroblastoma cells
    Mahesh B Shenai
    Medical School, University of Michigan, Ann Arbor, MI 48105, USA
    IEEE Trans Nanobioscience 3:111-7. 2004
    ..Ultimately, this platform can be used to nanocharacterize cell responses to electric stimulation and other biochemical cues, for use in neuronal patterning and regeneration studies...
  20. ncbi request reprint Direct observation of lipid bilayer disruption by poly(amidoamine) dendrimers
    Almut Mecke
    Department of Physics, University of Michigan, 500 E University Avenue, Ann Arbor, MI 48109, USA
    Chem Phys Lipids 132:3-14. 2004
    ..The fact that tectodendrimers behave differently suggests that their cluster-like architecture plays an important role in their interaction with the lipid bilayer...
  21. ncbi request reprint Atomic force microscopy study of early morphological changes during apoptosis
    Jessica A Hessler
    Department of Chemistry, and the Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI 48109 1055, USA
    Langmuir 21:9280-6. 2005
    ..This suggests that morphological volume changes occur very early in the induction of apoptosis...
  22. pmc Interactions of poly(amidoamine) dendrimers with Survanta lung surfactant: the importance of lipid domains
    Blake Erickson
    Program in Biophysics, University of Michigan, Ann Arbor, Michigan 48109, USA
    Langmuir 24:11003-8. 2008
    ..Immediately following lipid removal, the mica surface is clean, indicating that lipid defects are not induced by dendrimers binding to the mica substrate and displacing the lipid...
  23. pmc Membrane thinning due to antimicrobial peptide binding: an atomic force microscopy study of MSI-78 in lipid bilayers
    Almut Mecke
    University of Michigan, Ann Arbor, Michigan, USA
    Biophys J 89:4043-50. 2005
    ..Furthermore, 2H NMR experiments on DMPC-d54 multilamellar vesicles indicate that the acyl chains of DMPC are highly disordered in the presence of the peptide as is to be expected for the proposed structure of the peptide-lipid assembly...
  24. ncbi request reprint Interaction of polycationic polymers with supported lipid bilayers and cells: nanoscale hole formation and enhanced membrane permeability
    Seungpyo Hong
    Program in Applied Physics, Department of Chemistry, and Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA
    Bioconjug Chem 17:728-34. 2006
    ....
  25. pmc Nanoparticle interaction with biological membranes: does nanotechnology present a Janus face?
    Pascale R Leroueil
    Program in Macromolecular Science and Engineering, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA
    Acc Chem Res 40:335-42. 2007
    ....
  26. ncbi request reprint Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: hole formation and the relation to transport
    Seungpyo Hong
    Program in Applied Physics, Department of Internal Medicine, University of Michigan, Ann Arbor 48109, USA
    Bioconjug Chem 15:774-82. 2004
    ..Diffusion of dendrimers through holes is sufficient to explain the uptake of G5 amine-terminated PAMAM dendrimers into cells and is consistent with the lack of uptake of G5 acetamide-terminated PAMAM dendrimers...