Steven N Hochwald

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi Preoperative radiotherapy alone or combined with chemotherapy followed by transanal excision for rectal adenocarcinoma
    Kenyon Meadows
    Department of Radiation Oncology, University of Florida, Gainesville, FL 32510 0385, USA
    Am J Clin Oncol 29:430-4. 2006
  2. doi Epitrochlear lymph node dissection
    Steven N Hochwald
    Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA
    Ann Surg Oncol 18:505. 2011
  3. doi Braun enteroenterostomy is associated with reduced delayed gastric emptying and early resumption of oral feeding following pancreaticoduodenectomy
    Steven N Hochwald
    Division of Surgical Oncology and Endocrine Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    J Surg Oncol 101:351-5. 2010
  4. doi Elevation of serum IgG4 in Western patients with autoimmune sclerosing pancreatocholangitis: a word of caution
    Steven N Hochwald
    Division of Surgical Oncology, Department of Surgery, University of Florida College of Medicine, 1600 SW Archer Road, 100286, Gainesville, Florida, USA
    Ann Surg Oncol 15:1147-54. 2008
  5. doi Minimally invasive esophagectomy is safe and effective following neoadjuvant chemoradiation therapy
    Kfir Ben-David
    Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA
    Ann Surg Oncol 18:3324-9. 2011
  6. pmc Disruption of the protein interaction between FAK and IGF-1R inhibits melanoma tumor growth
    Deniz A Ucar
    Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA
    Cell Cycle 11:3250-9. 2012
  7. pmc Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivo
    Deniz A Ucar
    Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA
    Anticancer Agents Med Chem 13:595-602. 2013
  8. ncbi Esophagectomy in the state of Florida: is regionalization of care warranted?
    Kfir Ben-David
    Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Am Surg 78:291-5. 2012
  9. doi Reoperative surgery in sporadic Zollinger-Ellison Syndrome: longterm results
    Stephen R Grobmyer
    Department of Surgery, Division of Surgical Oncology, University of Florida, Gainesville, FL 32610, USA
    J Am Coll Surg 208:718-22; discussion 722-4. 2009
  10. doi Esophageal cancer--the five year survivors
    Tad Kim
    Division of Surgical Oncology, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA
    J Surg Oncol 103:179-83. 2011

Collaborators

Detail Information

Publications77

  1. ncbi Preoperative radiotherapy alone or combined with chemotherapy followed by transanal excision for rectal adenocarcinoma
    Kenyon Meadows
    Department of Radiation Oncology, University of Florida, Gainesville, FL 32510 0385, USA
    Am J Clin Oncol 29:430-4. 2006
    ..To evaluate the efficacy of preoperative radiotherapy (RT) and chemoradiation (CRT) followed by transanal excision (TAE) for rectal adenocarcinoma...
  2. doi Epitrochlear lymph node dissection
    Steven N Hochwald
    Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA
    Ann Surg Oncol 18:505. 2011
    ..This streaming video demonstrates the incidence of epitrochlear lymph node involvement and technical considerations associated with epitrochlear lymph node dissection...
  3. doi Braun enteroenterostomy is associated with reduced delayed gastric emptying and early resumption of oral feeding following pancreaticoduodenectomy
    Steven N Hochwald
    Division of Surgical Oncology and Endocrine Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    J Surg Oncol 101:351-5. 2010
    ..A Braun enteroenterostomy has been shown to decrease bile reflux following gastric resection. We hypothesize that addition of Braun enteroenterostomy during PD would reduce the sequelae of DGE...
  4. doi Elevation of serum IgG4 in Western patients with autoimmune sclerosing pancreatocholangitis: a word of caution
    Steven N Hochwald
    Division of Surgical Oncology, Department of Surgery, University of Florida College of Medicine, 1600 SW Archer Road, 100286, Gainesville, Florida, USA
    Ann Surg Oncol 15:1147-54. 2008
    ..Serum immunoglobin (Ig) G4 values seem to be helpful in distinguishing autoimmune pancreatocholangitis from pancreatic malignancy in the Japanese population; however, its significance in the Western population has not been well studied...
  5. doi Minimally invasive esophagectomy is safe and effective following neoadjuvant chemoradiation therapy
    Kfir Ben-David
    Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA
    Ann Surg Oncol 18:3324-9. 2011
    ..Despite widespread concern about the successful performance of this procedure following neoadjuvant chemoradiotherapy (NACR) treatment, we hypothesized that safe and effective MIE could be performed in this setting...
  6. pmc Disruption of the protein interaction between FAK and IGF-1R inhibits melanoma tumor growth
    Deniz A Ucar
    Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA
    Cell Cycle 11:3250-9. 2012
    ..Our data suggest that the FAK-IGF-1R protein interaction is an important target, and disruption of this interaction with a novel small molecule (INT2-31) has potential anti-neoplastic therapeutic effects in human melanoma...
  7. pmc Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivo
    Deniz A Ucar
    Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA
    Anticancer Agents Med Chem 13:595-602. 2013
    ..In addition, INT2-31 increases sensitivity to gemcitabine chemotherapy in a direct fresh biopsy xenograft model of pancreatic cancer growth...
  8. ncbi Esophagectomy in the state of Florida: is regionalization of care warranted?
    Kfir Ben-David
    Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Am Surg 78:291-5. 2012
    ..These data support the regionalization of esophagectomy to high-volume locations in Florida to reduce procedure-related mortality...
  9. doi Reoperative surgery in sporadic Zollinger-Ellison Syndrome: longterm results
    Stephen R Grobmyer
    Department of Surgery, Division of Surgical Oncology, University of Florida, Gainesville, FL 32610, USA
    J Am Coll Surg 208:718-22; discussion 722-4. 2009
    ..There is currently no consensus about managing patients with recurrent or persistent ZES. Our unit has historically maintained an aggressive approach toward monitoring and reoperation for patients with sporadic ZES...
  10. doi Esophageal cancer--the five year survivors
    Tad Kim
    Division of Surgical Oncology, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA
    J Surg Oncol 103:179-83. 2011
    ..Esophageal cancer in the United States carries a poor prognosis with overall 5 year survival rate of approximately 10%. Due to this dismal outcome, data analyzing factors predictive of survival for greater than 5 years are not available...
  11. pmc A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer
    Steven N Hochwald
    Department of Surgery, Roswell Park Cancer Institute, Buffalo, NY, USA
    Cell Cycle 8:2435-43. 2009
    ..Thus, targeting the Y397 site of FAK in pancreatic cancer with the small molecule inhibitor, 1,2,4,5-Benzenetetraamine tetrahydrochloride, is a potentially effective treatment strategy in this deadly disease...
  12. doi Nanoparticle delivery for metastatic breast cancer
    Stephen R Grobmyer
    Division of Surgical Oncology, Department of Surgery, University of Florida, Gainesville, Florida 32610, USA
    Nanomedicine 8:S21-30. 2012
    ..Future translational approaches will rely on an ever increasing understanding of the biology of breast cancer subtypes and their metastases. These important concepts will be highlighted and elucidated in this manuscript...
  13. ncbi A novel small molecule inhibitor of FAK and IGF-1R protein interactions decreases growth of human esophageal carcinoma
    Deniz A Ucar
    Department of Surgery, University of Florida College of Medicine, Gainesville, FL 32610, USA
    Anticancer Agents Med Chem 11:629-37. 2011
    ..Our hypothesis is that a novel small molecule compound that disrupts FAK and IGF-1R protein-protein interactions (PPIs) would decrease the growth of human esophageal cancer...
  14. pmc A multi-institutional experience of repeat regional chemotherapy for recurrent melanoma of extremities
    Christy Y Chai
    Department of Surgery, San Antonio Military Medical Center, San Antonio, TX, USA
    Ann Surg Oncol 19:1637-43. 2012
    ..The role and efficacy of repeat regional chemotherapy for recurrence and which salvage procedure is better remains debatable. We aimed to compare toxicities and clinical outcomes by procedure types and the sequence...
  15. doi Is there an indication for initial conservative management of pancreatic cystic lesions?
    Stephen R Grobmyer
    Division of Surgical Oncology, Department of Surgery, University of Florida College of Medicine, Gainesville, FL 32610, USA
    J Surg Oncol 100:372-4. 2009
    ..The management of small pancreatic cystic lesions presents a clinical challenge...
  16. ncbi Inducible nuclear factor-kappaB activation contributes to chemotherapy resistance in gastric cancer
    E Ramsay Camp
    Department of Surgery, University of Florida College of Medicine, Gainesville, FL 32610, USA
    J Am Coll Surg 199:249-58. 2004
    ..Inhibition of NF-kappaB by adenoviral delivery of an IkappaBalpha superrepressor (Ad.IkappaBalpha-SR) should potentiate 5-fluorouracil (5-FU) and irinotecan chemotherapy in gastric cancer cells...
  17. pmc A novel strategy to inhibit FAK and IGF-1R decreases growth of pancreatic cancer xenografts
    Donghang Zheng
    Department of Surgery, University of Florida, Gainesville, Florida, USA
    Mol Carcinog 49:200-9. 2010
    ..The current study demonstrates the importance of dual inhibition of both these signaling pathways as a novel strategy to decrease both in vitro and in vivo growth of human pancreatic cancer...
  18. doi Recurrent retroperitoneal sarcoma: impact of biology and therapy on outcomes
    Stephen R Grobmyer
    Department of Surgery, Division of Surgical Oncology, University of Florida, Gainesville, FL 32610, USA
    J Am Coll Surg 210:602-8, 608-10. 2010
    ..Local recurrence remains the major cause of death in patients with retroperitoneal sarcoma (RPS). There is no consensus regarding management of patients with recurrent RPS...
  19. doi A multi-institutional experience of isolated limb infusion: defining response and toxicity in the US
    Georgia M Beasley
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Am Coll Surg 208:706-15; discussion 715-7. 2009
    ..Establishing response and toxicity to ILI as compared with hyperthermic isolated limb perfusion is important for optimizing future regional chemotherapeutic strategies in melanoma...
  20. doi Pre-therapy laparoscopic feeding jejunostomy is safe and effective in patients undergoing minimally invasive esophagectomy for cancer
    Kfir Ben-David
    Department of Surgery, College of Medicine, University of Florida, Gainesville, FL 32610 0109, USA
    J Gastrointest Surg 17:1352-8. 2013
    ..Laparoscopic feeding jejunostomy is a safe and effective means of providing enteral nutrition in the preoperative phase to esophageal cancer patients...
  21. doi Decreasing morbidity and mortality in 100 consecutive minimally invasive esophagectomies
    Kfir Ben-David
    Department of Surgery, University of Florida College of Medicine, 1600 SW Archer Road, Room 6164, P O Box 100109, Gainesville, FL 32610, USA
    Surg Endosc 26:162-7. 2012
    ..We reviewed our minimally invasive esophagectomy (MIE) experience of a consecutive series of 100 patients to analyze trends in morbidity and mortality as we transitioned from open to MIE...
  22. doi Magnetic resonance imaging for axillary staging in patients with breast cancer
    Vincent E Mortellaro
    Division of Surgical Oncology, Department of Surgery, University of Florida, Gainesville, Florida 32610, USA
    J Magn Reson Imaging 30:309-12. 2009
    ..To determine the utility of MRI for assessing axillary lymph node status in patients with breast cancer...
  23. doi Autoimmune pancreatitis and concurrent small lymphocytic lymphoma: not just a coincidence?
    Tad Kim
    Division of Surgical Oncology, University of Florida College of Medicine, 1600 SW Archer Road, Gainesville, FL 32610, USA
    J Gastrointest Surg 12:1566-70. 2008
    ..Histologic analysis of the pancreatic head revealed a lymphoplasmacytic infiltrate with stromal fibrosis consistent with autoimmune pancreatitis. The retroperitoneal lymph nodes were involved by small lymphocytic lymphoma...
  24. ncbi Presentation and management of gastrointestinal stromal tumors of the duodenum
    Robert D Winfield
    Department of Surgery, Division of Surgical Oncology and Endocrine Surgery, The College of Medicine, University of Florida, Gainesville, Florida, USA
    Am Surg 72:719-22; discussion 722-3. 2006
    ..Duodenal GIST are relatively rare tumors that present most commonly with gastrointestinal bleeding. Duodenal GIST are associated with neurofibromatosis. Many duodenal GIST require pancreaticoduodenectomy for complete removal...
  25. ncbi Enhanced sensitivity to chemotherapy in esophageal cancer through inhibition of NF-kappaB
    Jing Li
    Department of Surgery, University of Florida College of Medicine, Gainesville, 32610, USA
    J Surg Res 132:112-20. 2006
    ..Therefore, inhibition of NF-kappaB by adenoviral delivery of an IkappaBalpha super-repressor (Ad.IkappaBalpha-SR) should make esophageal cancer cells more sensitive to 5- fluorouracil (5-FU) and taxotere chemotherapy...
  26. doi Minimally invasive esophagectomy with cervical esophagogastric anastomosis
    Steven N Hochwald
    Department of Surgery, University of Florida College of Medicine, 1600 SW Archer Road, P O Box 100109, Gainesville, FL 32610, USA
    J Gastrointest Surg 16:1775-81. 2012
    ..Thoracoscopic dissection of the esophagus and laparoscopic dissection of the stomach with cervical esophagogastric anastomosis is a safe method for resection of esophageal and gastroesophageal junction malignancy...
  27. ncbi Elevated expression of IRS2 in the progression from neurofibroma to malignant peripheral nerve sheath tumor
    Christiana M Shaw
    Division of Surgical Oncology, Department of Surgery, University of Florida College of Medicine, 1600 SW Archer Road, P O Box 100109, Gainesville, FL 32610 0109, USA
    Anticancer Res 32:439-43. 2012
    ..As a result, defining expression of proteins in these pathways; in select tumors is important in order to formulate therapeutic approaches to malignant peripheral nerve sheath tumors (MPNSTs)...
  28. doi Multimodality local therapy for retroperitoneal sarcoma
    Nitesh N Paryani
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA
    Int J Radiat Oncol Biol Phys 82:1128-34. 2012
    ..This study updates our institutional experience using multimodality local therapy for resectable retroperitoneal sarcoma and identifies prognostic factors impacting disease control and survival...
  29. ncbi Long-term results of a selective surgical approach to management of Zollinger-Ellison syndrome in patients with MEN-1
    Vincent E Mortellaro
    Division of Surgical Oncology, Department of Surgery, University of Florida, 1600 SW Archer Road, Gainesville, Florida 32609, USA
    Am Surg 75:730-3. 2009
    ..Operations rarely result in biochemical cures in patients with MEN-1 and ZES. In our experience, resection of localized gastrinomas often did not require extended surgical resection and were associated with excellent long-term outcomes...
  30. ncbi Retroperitoneal soft tissue sarcoma
    William M Mendenhall
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL 32610, USA
    Cancer 104:669-75. 2005
    ..Most patients experienced recurrent disease after surgery, and the most common site of failure was local. Adjuvant RT reduced the risk of local recurrence, but its impact on survival was questionable...
  31. ncbi Adjuvant radiation therapy for resectable retroperitoneal soft tissue sarcoma: the University of Florida experience
    Robert A Zlotecki
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida 32610 0385, USA
    Am J Clin Oncol 28:310-6. 2005
    ..In the management of retroperitoneal sarcomas it is necessary to achieve local control to ensure survival. The role of adjuvant radiation therapy (RT), either pre- or postoperative, remains controversial...
  32. ncbi Reoperative surgery for the Zollinger-Ellison syndrome
    Stephen R Grobmyer
    Division of Surgical Oncology, Department of Surgery, University of Florida, 1600 SW Archer Road, Room 6165, P O Box 100109, Gainesville, FL 32610, USA
    Adv Surg 44:327-46. 2010
    ..A thorough knowledge of the natural history of the sporadic form of ZES and ZES in the context of MEN-1, patterns of presentation, and sites of metastases are necessary to achieve the best outcome in patients with this unusual disease...
  33. doi Adjuvant radiotherapy for cutaneous melanoma
    William M Mendenhall
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida 32610 0385, USA
    Cancer 112:1189-96. 2008
    ..Postoperative adjuvant RT results in locoregional control rates of 85% to 90% or higher in high-risk patients with a modest risk of complications. The impact of adjuvant RT on survival is likely minimal...
  34. doi Contemporary results with ampullectomy for 29 "benign" neoplasms of the ampulla
    Stephen R Grobmyer
    Division of Surgical Oncology and Endocrine Surgery, University of Florida, Gainesville, FL 32610, USA
    J Am Coll Surg 206:466-71. 2008
    ..Ampullectomy may be an appropriate oncologic procedure in selected patients. Sparse data exist on procedure-related complications and the relationship between histologic analysis and outcomes...
  35. pmc Isolated metastatic extremity liposarcoma to the liver, an uncommon and transient finding
    Christopher A Garces
    Department of Surgery, Division of Surgical Oncology, University of Florida, Gainesville, Florida 32610, USA
    World J Surg Oncol 6:108. 2008
    ..Due to the unusual occurrence of isolated metastatic extremity liposarcoma to the liver, the optimal treatment of this condition is unknown...
  36. doi Utilization of minimally invasive breast biopsy for the evaluation of suspicious breast lesions
    Luke G Gutwein
    Department of Surgery, Division of Acute Care Surgery, University of Florida, Gainesville, FL, USA
    Am J Surg 202:127-32. 2011
    ..The purpose of this study is to determine modern rates of MIBB and open breast biopsy...
  37. pmc Targeting of the protein interaction site between FAK and IGF-1R
    Donghang Zheng
    Department of Surgery, University of Florida, Gainesville, FL, USA
    Biochem Biophys Res Commun 388:301-5. 2009
    ..This strategy successfully identified a lead compound that disrupts FAK/IGF-1R interaction...
  38. ncbi Breast MR for the evaluation of occult nipple discharge
    Vincent E Mortellaro
    Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida, USA
    Am Surg 74:739-42. 2008
    ..The use of breast MR in this setting may permit directed evaluation and management of potentially malignant lesions...
  39. doi Malignant Peripheral Nerve Sheath Tumor: molecular pathogenesis and current management considerations
    Stephen R Grobmyer
    Department of Surgery, Division of Surgical Oncology and Endocrine Surgery, University of Florida, Gainesville, Florida, USA
    J Surg Oncol 97:340-9. 2008
    ..There are many recent advances in the understanding of the molecular pathogenesis of MPNST which represent the best opportunities to develop new strategies for management of patients with MPNST...
  40. pmc FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells
    Weiguo Liu
    Division of Surgical Oncology, University of Florida College of Medicine, Gainesville, FL 32610, USA
    Carcinogenesis 29:1096-107. 2008
    ..Thus, simultaneous inhibition of both tyrosine kinases represents a potential novel therapeutic approach in human pancreatic adenocarcinoma...
  41. doi Technique of minimally invasive Ivor Lewis esophagogastrectomy with intrathoracic stapled side-to-side anastomosis
    Kfir Ben-David
    Department of Surgery, University of Florida College of Medicine, 1600 SW Archer Road, P O Box 100109, Gainesville, FL 32610, USA
    J Gastrointest Surg 14:1613-8. 2010
    ..An intrathoracic linear stapled side-to-side anastomosis for gastroesophageal junction malignancy is feasible, results in low leak rates and less stenosis...
  42. doi Nanoparticle delivery for metastatic breast cancer
    Stephen R Grobmyer
    Division of Surgical Oncology, Department of Surgery, University of Florida, Gainesville, FL 32610, USA
    Maturitas 73:19-26. 2012
    ..Future translational approaches will rely on an ever increasing understanding of the biology of breast cancer subtypes and their metastases. These important concepts will be highlighted and elucidated in this manuscript...
  43. doi Predictive factors of regional toxicity and serum creatine phosphokinase levels after isolated limb infusion for melanoma: a multi-institutional analysis
    Alfredo A Santillan
    Division of Cutaneous Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
    Ann Surg Oncol 16:2570-8. 2009
    ..Determining perioperative factors that could predict toxicity is important to optimize strategies to improve clinical outcomes after regional chemotherapy in melanoma...
  44. doi A pilot prospective randomized trial of postoperative epoetin alfa in patients undergoing major operation for upper gastrointestinal malignancy
    Stephen R Grobmyer
    Departments of Surgery, University of Florida, Gainesville, FL, USA
    Am J Clin Oncol 32:570-3. 2009
    ..Strategies to reduce red blood transfusion utilization in cancer patients undergoing operation are needed...
  45. ncbi Inhibition of NF-kappa B augments sensitivity to 5-fluorouracil/folinic acid in colon cancer
    Rene Voboril
    Department of Surgery, Division of Surgical Oncology, University of Florida College of Medicine, 1600 SW Archer Road, Room 6184, Gainesville, FL 32610, USA
    J Surg Res 120:178-88. 2004
    ..Limited research suggests that the transcription factor nuclear factor kappa-B (NF-kappaB), which has antiapoptotic properties, may play a major role in inducible chemoresistance...
  46. ncbi Is endoscopic resection of gastric gastrointestinal stromal tumors safe?
    Alyson L Waterman
    Division of Surgical Oncology, Department of Surgery, University of Florida, Gainesville, Florida 32610, USA
    Am Surg 74:1186-9. 2008
    ..Complete transperitoneal excision (either open or laparoscopic) with clear margins and without tumor rupture remains the gold standard for management of gastric GIST...
  47. doi Novel pancreaticojejunostomy with a low rate of anastomotic failure-related complications
    Stephen R Grobmyer
    Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, University of Florida, Gainesville, FL, USA
    J Am Coll Surg 210:54-9. 2010
    ..The pancreaticojejunostomy described by one of the authors (LHB) meets the criteria for an "ideal" pancreaticojejunostomy...
  48. pmc Targeting Focal Adhesion Kinase and Resistance to mTOR Inhibition in Pancreatic Neuroendocrine Tumors
    Rony A Francois
    Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, FL RAF, km, AN, MZK Department of Medicine, University of Florida College of Medicine, Gainesville, FL FJK Department of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, NY SNH
    J Natl Cancer Inst 107:. 2015
    ..Because mTOR inhibitors rarely induce PanNET tumor regression, partly because of feedback activation of AKT, novel combination strategies are needed to target FAK/AKT/mTOR signaling...
  49. doi Minimally Invasive Esophagectomy Utilizing a Stapled Side-to-Side Anastomosis is Safe in the Western Patient Population
    Kfir Ben-David
    Department of Surgery, Mount Sinai Medical Center, Miami Beach, FL, USA
    Ann Surg Oncol 23:3056-62. 2016
    ..However, there are limited large series of patients undergoing MIE from the United States and no standardized approach. We reviewed our experience with MIE utilizing a stapled side-to-side anastomosis during a 7.5-year period...
  50. ncbi Adjuvant postoperative radiotherapy for colon carcinoma
    William M Mendenhall
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville 32610, USA
    Cancer 101:1338-44. 2004
    ..The objective of this report was to review the role of adjuvant postoperative radiotherapy (RT) for patients with adenocarcinoma of the colon...
  51. ncbi FAK and interacting proteins as therapeutic targets in pancreatic cancer
    Deniz A Ucar
    Department of Surgery, University of Florida College of Medicine, Gainesville, 32610, USA
    Anticancer Agents Med Chem 10:742-6. 2010
    ..The role of FAK in the pathogenesis of pancreatic cancer is discussed below and efforts aimed at the development of inhibitors of FAK for this disease are reviewed...
  52. doi Autoimmune esophagitis: IgG4-related tumors of the esophagus
    James Lopes
    Department of Surgery, University of Florida College of Medicine, 1600 SW Archer Road, PO Box 100109, Gainesville, FL 32610, USA
    J Gastrointest Surg 14:1031-4. 2010
    ..We present the pre-operative imaging, operative management, pathologic diagnosis, and literature review of this rare condition and the first known report of autoimmune esophagitis as part of the IgG4 spectrum of diseases...
  53. ncbi Isolated lymphoplasmacytic sclerosing pancreatitis involving the pancreatic tail
    Tad Kim
    Division of Surgical Oncology, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Am Surg 74:654-8. 2008
    ..IgG4 levels may assist in recognition of this disease. As our experience with utilization of IgG4 testing and knowledge of the systemic nature of LPSP increase, patients with this disease may be spared unnecessary resection...
  54. ncbi Nodular fasciitis: differential considerations and current management strategies
    Stephen R Grobmyer
    Division of Surgical Oncology, Department of Surgery, University of Florida, Gainesville, Florida, USA
    Am Surg 75:610-4. 2009
    ..These cases highlight the clinical issues associated with management of patients with NF. Current approaches to evaluation, diagnosis, and treatment of NF are discussed...
  55. pmc Pancreatic stent placement is associated with resolution of refractory grade C pancreatic fistula after left-sided pancreatectomy
    Stephen R Grobmyer
    Division of Surgical Oncology, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32609, USA
    Am Surg 75:654-7; discussion 657-8. 2009
    ..Endoscopic pancreatic stents were associated with resolution of Grade C fistulas. After distal pancreatectomy, pancreatic stent placement should be considered in the postoperative period for refractory pancreatic fistulas...
  56. doi Is there a role for routine use of MRI in selection of patients for breast-conserving cancer therapy?
    Stephen R Grobmyer
    Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, FL 32610, USA
    J Am Coll Surg 206:1045-50; discussion 1050-2. 2008
    ....
  57. ncbi Role of radiation therapy in the treatment of resectable rectal adenocarcinoma
    William M Mendenhall
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida 32611, USA
    J Surg Oncol 79:107-17; discussion 118. 2002
    ..The purpose of this study is to review the role of radiation therapy in the treatment of resectable rectal adenocarcinoma. Selection criteria, treatment techniques, and results are discussed...
  58. doi Minimally invasive esophagectomy is safe in patients with previous gastric bypass
    Georgios Rossidis
    Department of Surgery, University of Florida College of Medicine, Gainesville, Florida
    Surg Obes Relat Dis 10:95-100. 2014
    ..We present our case series of consecutive patients with previous GB who underwent minimally invasive esophagectomy (MIE)...
  59. doi DNA methyltransferase inhibitor, zebularine, delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer
    Min Chen
    Department of Anatomy and Cell Biology, University of Florida, College of Medicine, Gainesville, FL 32610, USA
    Mol Cancer Ther 11:370-82. 2012
    ..Defining the parameters of zebularine-mediated tumor inhibition may advance the future development of DNA methyltransferase inhibitors as an effective cancer treatment...
  60. ncbi Emerging implications of nanotechnology on cancer diagnostics and therapeutics
    Alex G Cuenca
    Division of Surgical Oncology, Department of Surgery, University of Florida, Gainesville, Florida 32610, USA
    Cancer 107:459-66. 2006
    ..A widespread understanding of these new technologies is important, because they currently are being integrated into the clinical practice of oncology...
  61. ncbi Aggressive fibromatosis
    William M Mendenhall
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida, USA
    Am J Clin Oncol 28:211-5. 2005
    ..Pharmacologic treatment should be considered for patients with progressive disease after unsuccessful local-regional therapy...
  62. pmc Primary presacral neuroendocrine tumor associated with imperforate anus
    Tad Kim
    Division of Surgical Oncology, University of Florida, College of Medicine, Gainesville, FL 32610, USA
    World J Surg Oncol 5:115. 2007
    ..Neuroendocrine tumors of the presacral region are extremely rare and few have been described in the literature. They have not been previously reported as being associated with imperforate anus...
  63. ncbi Determining prognosis in patients with pancreatic endocrine neoplasms: can the WHO classification system be simplified?
    Cristina R Ferrone
    Department of Surgery, Memorial Sloan Kettering Cancer Center, Howard 1223, 1275 York Ave, New York, NY 10021, USA
    J Clin Oncol 25:5609-15. 2007
    ..This study compares the prognostic value of a simplified staging and grading system with the WHO system in a large single-institution study...
  64. doi Molecular-targeted therapy for cancer and nanotechnology
    Steven N Hochwald
    Department of Surgery, University of Florida, Gainesville, FL, USA
    Methods Mol Biol 624:11-23. 2010
    ..A discussion of relevant targets either on the cell surface or the cytoplasm and strategies to achieve optimal drug targeting are the focus of this chapter...
  65. ncbi A case of dual thoracoabdominal impalement in vehicular trauma
    Robert D Winfield
    Division of Acute Care, Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Am Surg 74:757-60. 2008
    ....
  66. ncbi Antineoplastic therapy in colorectal cancer through proteasome inhibition
    Steven N Hochwald
    Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Am Surg 69:15-23. 2003
    ..Other potentially useful ways to promote apoptosis in cancer cells include the utilization of proteasome inhibitors. Such inhibitors are currently being evaluated in clinical trials...
  67. pmc Preoperative portal vein embolization for extended hepatectomy
    Alan W Hemming
    Department of Surgery, Center for Hepatobiliary Disease, University of Florida, Gainesville, FL 32610, USA
    Ann Surg 237:686-91; discussion 691-3. 2003
    ..To examine the authors' experience with preoperative ipsilateral portal vein embolization (PVE) and assess its role in extended hepatectomy...
  68. ncbi FAP with concurrent duodenal adenomatous polyposis and carcinoid tumor
    E Ramsay Camp
    Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    J Surg Oncol 87:187-90. 2004
    ..No genetic basis exists explaining the link between FAP and carcinoid tumors. However, the presence of two rare entities in the same patient might suggest an association and further research may be indicated...
  69. ncbi Neoadjuvant therapy in the treatment of solid tumors
    Christopher A Garces
    General Surgery, University of Florida College of Medicine, Gainesville, FL, USA
    Curr Probl Surg 43:457-551. 2006
  70. ncbi Role of endoscopic ultrasound (EUS) and EUS-guided fine needle aspiration in the diagnosis and treatment of cystic lesions of the pancreas
    Lyndon V Hernandez
    University of Florida, Division of Gastroenterology, Hepatology, and Nutrition, Gainesville, Florida, USA
    Pancreas 25:222-8. 2002
    ..We assessed the utility of EUS-guided fine-needle aspiration (EUS-FNA) to assist in the diagnosis and management of pancreatic cysts...
  71. ncbi Prognostic factors in pancreatic endocrine neoplasms: an analysis of 136 cases with a proposal for low-grade and intermediate-grade groups
    Steven N Hochwald
    Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA
    J Clin Oncol 20:2633-42. 2002
    ..The purpose of this study was to evaluate prognostic factors in pancreatic endocrine neoplasms recently treated at a single institution...
  72. ncbi Metastatic potential of dermatofibrosarcoma protuberans with fibrosarcomatous change
    Rebecca M Minter
    Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    J Surg Oncol 82:201-8. 2003
    ..Metastases remain rare, however, and are typically preceded by multiple local recurrences. We report a rare case of a DFSP-FS metastasis to the head of the pancreas without any preceding local recurrence...
  73. ncbi Focal adhesion kinase signaling and function in pancreatic cancer
    Deniz A Ucar
    Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Front Biosci (Elite Ed) 3:750-6. 2011
    ..The role of FAK in the pathogenesis of pancreatic cancer is discussed below and efforts aimed at the development of inhibitors of FAK for this disease are reviewed...
  74. ncbi Significance of micrometastases in colorectal cancer
    Robert J Feezor
    Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    Ann Surg Oncol 9:944-53. 2002
  75. ncbi Squamous cell carcinoma of the anal margin
    Heather E Newlin
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida, USA
    J Surg Oncol 86:55-62; discussion 63. 2004
    ..To define the optimal treatment of patients with squamous cell carcinoma (SCCA) of the anal margin...
  76. ncbi Sequential dermal-peritumoral radiocolloid injection for sentinel node biopsy for breast cancer: the University of Florida experience
    Robert J Feezor
    Department of Surgery, University of Florida College of Medicine, Gainesville 32610 00286, USA
    Am Surg 68:684-7; discussion 687-8. 2002
    ..Delineation of nonaxillary SLNs may lead to more accurate breast cancer staging and may also influence the delivery of IM node radiation...
  77. ncbi Pleomorphic pancreatic endocrine neoplasms: a variant commonly confused with adenocarcinoma
    Sui Y Zee
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 29:1194-200. 2005
    ..There does not appear to be prognostic significance to these nuclear changes, and the morphologic features of pleomorphic PENs otherwise resemble those of their conventional counterparts...