Werner Hoch

Summary

Affiliation: University of Houston
Country: USA

Publications

  1. ncbi request reprint The agrin/muscle-specific kinase pathway: new targets for autoimmune and genetic disorders at the neuromuscular junction
    Yohan Liyanage
    Neurosciences Group, Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UK
    Muscle Nerve 25:4-16. 2002
  2. ncbi request reprint Molecular dissection of neuromuscular junction formation
    Werner Hoch
    University of Houston, Science and Research Building 2, Houston, TX 77204 5001, USA
    Trends Neurosci 26:335-7. 2003
  3. ncbi request reprint Myasthenia gravis induced in mice by immunization with the recombinant extracellular domain of rat muscle-specific kinase (MuSK)
    Smita Jha
    Department of Biology and Biochemistry, University of Houston, TX 77204, USA
    J Neuroimmunol 175:107-17. 2006
  4. ncbi request reprint Antibodies in myasthenia gravis and related disorders
    Angela Vincent
    Neurosciences Group, Department of Clinical Neurology, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, United Kingdom
    Ann N Y Acad Sci 998:324-35. 2003

Collaborators

Detail Information

Publications4

  1. ncbi request reprint The agrin/muscle-specific kinase pathway: new targets for autoimmune and genetic disorders at the neuromuscular junction
    Yohan Liyanage
    Neurosciences Group, Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UK
    Muscle Nerve 25:4-16. 2002
    ..We then review the development of the NMJ, focusing on the important roles of nerve-derived agrin and MuSK in clustering of AChRs and other essential components of the NMJ...
  2. ncbi request reprint Molecular dissection of neuromuscular junction formation
    Werner Hoch
    University of Houston, Science and Research Building 2, Houston, TX 77204 5001, USA
    Trends Neurosci 26:335-7. 2003
    ..Analysis of the imperfect postsynaptic specializations of these mice has provided new insights into the complex postsynaptic differentiation process...
  3. ncbi request reprint Myasthenia gravis induced in mice by immunization with the recombinant extracellular domain of rat muscle-specific kinase (MuSK)
    Smita Jha
    Department of Biology and Biochemistry, University of Houston, TX 77204, USA
    J Neuroimmunol 175:107-17. 2006
    ..Myasthenic sera inhibited agrin-induced AChR aggregation in C2C12 myotubes. Conclusion: Anti-MuSK Abs induce MG, which might also result from blocking the agrin-signaling pathway...
  4. ncbi request reprint Antibodies in myasthenia gravis and related disorders
    Angela Vincent
    Neurosciences Group, Department of Clinical Neurology, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, United Kingdom
    Ann N Y Acad Sci 998:324-35. 2003
    ..These antibodies are not found in AChR antibody-positive MG and are predominantly IgG4. MuSK antibody positivity appears to be associated with more severe bulbar disease that can be difficult to treat effectively...