J K Hewitt

Summary

Affiliation: University of Colorado
Country: USA

Publications

  1. ncbi request reprint The genetics of obesity: what have genetic studies told us about the environment
    J K Hewitt
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309 0447, USA
    Behav Genet 27:353-8. 1997
  2. ncbi request reprint Interaction between MAO-A genotype and maltreatment in the risk for conduct disorder: failure to confirm in adolescent patients
    Susan E Young
    Institute for Behavioral Genetics, UCB 447, University of Colorado, Boulder, CO 80301, USA
    Am J Psychiatry 163:1019-25. 2006
  3. ncbi request reprint The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco
    Joanna S Zeiger
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
    Hum Mol Genet 17:724-34. 2008
  4. ncbi request reprint Relationships between personality and preferred substance and motivations for use among adolescent substance abusers
    Justin B Adams
    Department of Psychology, University of Colorado, Boulder, Colorado 80309 0447, USA
    Am J Drug Alcohol Abuse 29:691-712. 2003
  5. ncbi request reprint Contributions of genes and environments to stability and change in externalizing and internalizing problems during elementary and middle school
    Brett C Haberstick
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA
    Behav Genet 35:381-96. 2005
  6. pmc Common genetic and environmental influences on major depressive disorder and conduct disorder
    Anjali Subbarao
    Department of Psychology, University of Colorado, Boulder, CO, USA
    J Abnorm Child Psychol 36:433-44. 2008
  7. ncbi request reprint Genetic and environmental influences on ratings of manifest anxiety by parents and children
    T D Topolski
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309 0447, USA
    J Anxiety Disord 13:371-97. 1999
  8. ncbi request reprint Genetic and environmental contributions to retrospectively reported DSM-IV childhood attention deficit hyperactivity disorder
    B C Haberstick
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309 0477, USA
    Psychol Med 38:1057-66. 2008
  9. pmc Developmental epidemiology of drug use and abuse in adolescence and young adulthood: Evidence of generalized risk
    R H C Palmer
    Institute for Behavioral Genetics, UCB 447 Boulder, CO 80309 0447, USA
    Drug Alcohol Depend 102:78-87. 2009
  10. ncbi request reprint Genetic and environmental influences on age at sexual initiation in the Colorado Adoption Project
    J B Bricker
    Institute for Behavioral Genetics, University of Colorado, 447 UCB, Boulder, CO 80309, USA
    Behav Genet 36:820-32. 2006

Collaborators

Detail Information

Publications85

  1. ncbi request reprint The genetics of obesity: what have genetic studies told us about the environment
    J K Hewitt
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309 0447, USA
    Behav Genet 27:353-8. 1997
    ....
  2. ncbi request reprint Interaction between MAO-A genotype and maltreatment in the risk for conduct disorder: failure to confirm in adolescent patients
    Susan E Young
    Institute for Behavioral Genetics, UCB 447, University of Colorado, Boulder, CO 80301, USA
    Am J Psychiatry 163:1019-25. 2006
    ....
  3. ncbi request reprint The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco
    Joanna S Zeiger
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
    Hum Mol Genet 17:724-34. 2008
    ..These results indicate that early subjective response to nicotine may be a valuable endophenotype for genetic studies aimed at uncovering genes contributing to nicotine use and addiction...
  4. ncbi request reprint Relationships between personality and preferred substance and motivations for use among adolescent substance abusers
    Justin B Adams
    Department of Psychology, University of Colorado, Boulder, Colorado 80309 0447, USA
    Am J Drug Alcohol Abuse 29:691-712. 2003
    ....
  5. ncbi request reprint Contributions of genes and environments to stability and change in externalizing and internalizing problems during elementary and middle school
    Brett C Haberstick
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA
    Behav Genet 35:381-96. 2005
    ..Clinical implications of these findings are discussed...
  6. pmc Common genetic and environmental influences on major depressive disorder and conduct disorder
    Anjali Subbarao
    Department of Psychology, University of Colorado, Boulder, CO, USA
    J Abnorm Child Psychol 36:433-44. 2008
    ..Our results suggest that some genetic factors will increase an individual's vulnerability to both MDD and CD in adolescence...
  7. ncbi request reprint Genetic and environmental influences on ratings of manifest anxiety by parents and children
    T D Topolski
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309 0447, USA
    J Anxiety Disord 13:371-97. 1999
    ..These results highlight the need to focus on gender differences...
  8. ncbi request reprint Genetic and environmental contributions to retrospectively reported DSM-IV childhood attention deficit hyperactivity disorder
    B C Haberstick
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309 0477, USA
    Psychol Med 38:1057-66. 2008
    ....
  9. pmc Developmental epidemiology of drug use and abuse in adolescence and young adulthood: Evidence of generalized risk
    R H C Palmer
    Institute for Behavioral Genetics, UCB 447 Boulder, CO 80309 0447, USA
    Drug Alcohol Depend 102:78-87. 2009
    ..Our data also confirm either a generalized risk or correlated risk factors for early onset substance use and subsequent development of SUDs...
  10. ncbi request reprint Genetic and environmental influences on age at sexual initiation in the Colorado Adoption Project
    J B Bricker
    Institute for Behavioral Genetics, University of Colorado, 447 UCB, Boulder, CO 80309, USA
    Behav Genet 36:820-32. 2006
    ....
  11. ncbi request reprint The familial aggregation of depressive symptoms, antisocial behavior, and alcohol abuse
    M C Stallings
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309 0447, USA
    Am J Med Genet 74:183-91. 1997
    ..More important, correlations among the transmissible family factors for these psychiatric syndromes ranged from .58 to .73, suggesting substantial overlap among the underlying familial antecedents for these disorders...
  12. ncbi request reprint An exploration of the genetic and environmental etiology of heart rate in infancy and middle childhood
    C A Van Hulle
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309 0447, USA
    Twin Res 3:259-65. 2000
    ..Shared environment and non-shared environment also contributed a modicum to the stability across time. Thus, individual differences in resting heart rate is a relatively stable, heritable trait from infancy to early childhood...
  13. ncbi request reprint Stability of genetic and environmental influences on reading performance at 7, 12, and 16 years of age in the Colorado Adoption Project
    S J Wadsworth
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309, USA
    Behav Genet 31:353-9. 2001
    ..g., instructional methods, teachers, peers) for the development of individual differences in reading performance between 7 and 16 years of age...
  14. ncbi request reprint Genetic and environmental influences on behavioral disinhibition
    S E Young
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA
    Am J Med Genet 96:684-95. 2000
    ..These results suggest that a variety of adolescent problem behaviors may share a common underlying genetic risk...
  15. ncbi request reprint Early childhood heart rate does not predict externalizing behavior problems at age 7 years
    C A Van Hulle
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309 0447, USA
    J Am Acad Child Adolesc Psychiatry 39:1238-44. 2000
    ..This study explored the possibility of a similar relationship between heart rate and externalizing behavior problems...
  16. ncbi request reprint Genetic and environmental influences on child reports of manifest anxiety and symptoms of separation anxiety and overanxious disorders: a community-based twin study
    T D Topolski
    University of Colorado, Boulder, 80309 0447, USA
    Behav Genet 27:15-28. 1997
    ..40) were found to play a moderate role for SAD but could be dropped from the model for OAD and from all of the age groups for MANX, although the parameter approached significance among 11 yr to 13-year-old males...
  17. ncbi request reprint Parent-offspring resemblance for reading performance at 7, 12 and 16 years of age in the Colorado Adoption Project
    S J Wadsworth
    Institute for Behavioral Genetics, University of Colorado, 80309 0447, USA
    J Child Psychol Psychiatry 43:769-74. 2002
    ....
  18. ncbi request reprint Substance use, abuse and dependence in adolescence: prevalence, symptom profiles and correlates
    S E Young
    Institute for Behavioral Genetics, University of Colorado, Campus Box 447, Boulder, CO 80309, USA
    Drug Alcohol Depend 68:309-22. 2002
    ..A comparison of abuse and dependence symptom profiles shows some interesting variability across substances, and suggests that manifestations of a subset of symptoms are gender specific...
  19. pmc The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults
    Isabel R Schlaepfer
    Institute for Behavioral Genetics, Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
    Biol Psychiatry 63:1039-46. 2008
    ..Significant results were then replicated in a separate adult population-representative sample...
  20. ncbi request reprint Greater attention problems during childhood predict poorer executive functioning in late adolescence
    Naomi P Friedman
    Institute for Behavioral Genetics, 447 UCB, University of Colorado, Boulder, CO 80309, USA
    Psychol Sci 18:893-900. 2007
    ..These results support the hypothesis that attention problems primarily reflect difficulties with response inhibition...
  21. ncbi request reprint The inclusion of measured covariates in the Neale and Kendler model fitting approach
    Soo Hyun Rhee
    Institute for Behavioral Genetics, University of Colorado, Campus Box 447, Boulder, CO 80309, USA
    Behav Genet 37:423-32. 2007
    ..An example of 13 models examining the comorbidity between alcohol dependence and illicit drug dependence is presented...
  22. ncbi request reprint Delinquent peer affiliation and conduct problems: A twin study
    Tanya M M Button
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
    J Abnorm Psychol 116:554-64. 2007
    ..The magnitude of the genetic variance of conduct problems was contextually dependent on levels of delinquent peer affiliation and was greater at higher levels of delinquent peer affiliation...
  23. ncbi request reprint Early childhood temperament and the covariation between internalizing and externalizing behavior in school-aged children
    Soo Hyun Rhee
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309 0447, USA
    Twin Res Hum Genet 10:33-44. 2007
    ..A possible limitation of this study is that the covariation between temperament and behavior problems may be due to shared measurement variance, as parent ratings were used to assess both temperament and behavior problems...
  24. ncbi request reprint The human protein kinase C gamma gene (PRKCG) as a susceptibility locus for behavioral disinhibition
    Isabel R Schlaepfer
    Institute for Behavioral Genetics, University of Colorado, Boulder, USA, and Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
    Addict Biol 12:200-9. 2007
    ..This study provides the first exploration of the PRKCG gene and its association with behavioral disinhibition and warrants further study in other larger population samples...
  25. pmc Between- and within-family association test of the dopamine receptor D2 TaqIA polymorphism and alcohol abuse and dependence in a general population sample of adults
    Brett C Haberstick
    Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO 80309 0447, USA
    J Stud Alcohol Drugs 68:362-70. 2007
    ..The mixed results of association between the DRD2 TaqIA polymorphism and alcohol-use disorders may be the result of differences in sample size, phenotype definition, heterogeneity of the samples, and genetic admixture...
  26. ncbi request reprint Childhood maltreatment, subsequent antisocial behavior, and the role of monoamine oxidase A genotype
    David Huizinga
    Institute of Behavioral Science, University of Colorado, Boulder, 80303, USA
    Biol Psychiatry 60:677-83. 2006
    ..Despite wide interest in this hypothesis, results remain mixed from the few attempts at replication...
  27. ncbi request reprint Genes, time to first cigarette and nicotine dependence in a general population sample of young adults
    Brett C Haberstick
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
    Addiction 102:655-65. 2007
    ..To examine variation in nicotine dependence scores and covariation between different dependence symptoms...
  28. ncbi request reprint Progression from marijuana use to daily smoking and nicotine dependence in a national sample of U.S. adolescents
    David S Timberlake
    Institute for Behavioral Genetics, University of Colorado, Campus Box 447, Boulder, CO 80303, USA
    Drug Alcohol Depend 88:272-81. 2007
    ....
  29. ncbi request reprint Association of the neuronal nicotinic receptor beta2 subunit gene (CHRNB2) with subjective responses to alcohol and nicotine
    Marissa A Ehringer
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA
    Am J Med Genet B Neuropsychiatr Genet 144:596-604. 2007
    ..This study provides the first evidence for association between the CHRNB2 gene and nicotine- and alcohol-related phenotypes, and suggests that polymorphisms in CHRNB2 may be important in mediating early responses to nicotine and alcohol...
  30. pmc Item response theory analysis of DSM-IV cannabis abuse and dependence criteria in adolescents
    Christie A Hartman
    School of Medicine at the University of Colorado Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA
    J Am Acad Child Adolesc Psychiatry 47:165-73. 2008
    ..different levels of severity of substance involvement, to what degree do each of the 11 abuse and dependence criteria assess adolescent cannabis problems, and do the DSM-IV items function similarly across different adolescent populations?..
  31. pmc Do schools moderate the genetic determinants of smoking?
    Jason D Boardman
    Department of Sociology and Population Program, Institute of Behavioral Science, University of Colorado at Boulder, 327 UCB, Boulder, CO 80309 0327, USA
    Behav Genet 38:234-46. 2008
    ..These findings make important contributions to the literature on gene-environment interactions...
  32. pmc Bivariate analysis of disordered eating characteristics in adolescence and young adulthood
    Melissa A Munn
    Department of Psychology and Neuroscience, University of Colorado, Boulder, Colorado, USA
    Int J Eat Disord 43:751-61. 2010
    ..We examined the etiology of two disordered eating characteristics...
  33. pmc Dizziness and the genetic influences on subjective experiences to initial cigarette use
    Brett C Haberstick
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309 04477, USA
    Addiction 106:391-9. 2011
    ..To examine individual differences in positive and negative subjective experiences to initial cigarette use...
  34. pmc The etiology of stability and change in religious values and religious attendance
    Tanya M M Button
    Institute for Behavioral Genetics, University of Colorado at Boulder, 1480 30th Street, Boulder, CO 80309 0447, USA
    Behav Genet 41:201-10. 2011
    ....
  35. pmc The moderating effect of religiosity on the genetic variance of problem alcohol use
    Tanya M M Button
    Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, Colorado 80309 0447, USA
    Alcohol Clin Exp Res 34:1619-24. 2010
    ..g., urbanicity, marital status, and religiosity). The aim of the current study was to identify whether religiosity moderated the genetic variance of problem alcohol use in men and women at two time points: adolescence and early adulthood...
  36. pmc Subjective effects to marijuana associated with marijuana use in community and clinical subjects
    Joanna S Zeiger
    Institute for Behavioral Genetics, University of Colorado, 447 UCB, Boulder, CO 80309, United States
    Drug Alcohol Depend 109:161-6. 2010
    ..e. subjective effects). We have examined subjective effects in adolescent, young adult community, and clinical populations to determine how patterns of use may be predicted by an individual's subjective experiences with the drug...
  37. pmc Stable genes and changing environments: body mass index across adolescence and young adulthood
    Brett C Haberstick
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309 0447, USA
    Behav Genet 40:495-504. 2010
    ....
  38. pmc The association between cannabinoid receptor 1 gene (CNR1) and cannabis dependence symptoms in adolescents and young adults
    Christie A Hartman
    School of Medicine, University of Colorado at Denver, PO Box 6508, Mail Stop F478, Aurora, CO 80045, USA
    Drug Alcohol Depend 104:11-6. 2009
    ..This study examined the genetic association between variation in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence symptoms...
  39. pmc The developmental etiology of high IQ
    Angela M Brant
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309 0447, USA
    Behav Genet 39:393-405. 2009
    ....
  40. pmc Individual differences in childhood sleep problems predict later cognitive executive control
    Naomi P Friedman
    Institute for Behavioral Genetics, University of Colorado at Boulder Boulder CO 80309, USA
    Sleep 32:323-33. 2009
    ..To determine whether individual differences in developmental patterns of general sleep problems are associated with 3 executive function abilities-inhibiting, updating working memory, and task shifting-in late adolescence...
  41. pmc Investigation of genetically mediated child effects on maltreatment
    R Jay Schulz-Heik
    Department of Psychology, University of Colorado, Boulder, CO, USA
    Behav Genet 39:265-76. 2009
    ....
  42. pmc The association between conduct problems and maltreatment: testing genetic and environmental mediation
    R Jay Schulz-Heik
    Department of Psychology, University of Colorado, UCB 345, Boulder, CO 80309, USA
    Behav Genet 40:338-48. 2010
    ..Results were more consistent with the hypothesis that parents respond to children's genetically-influenced conduct problems by maltreating them than the hypothesis that maltreatment causes conduct problems...
  43. pmc Behavioral disinhibition: liability for externalizing spectrum disorders and its genetic and environmental relation to response inhibition across adolescence
    Susan E Young
    Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO 80309, USA
    J Abnorm Psychol 118:117-30. 2009
    ..These results highlight the dynamic nature of behavioral disinhibition across adolescence and suggest that response inhibition may be an important mechanism underlying vulnerability to disinhibitory psychopathology...
  44. pmc Perceived peer delinquency and the genetic predisposition for substance dependence vulnerability
    Tanya M M Button
    Institute for Behavioral Genetics, Campus Box 447, University of Colorado, Boulder, CO 80309, United States
    Drug Alcohol Depend 100:1-8. 2009
    ..The magnitudes of both shared and non-shared environmental influences were negligible among those who perceived their peers to be least delinquent and were greater among those with higher levels of perceived peers' delinquency...
  45. pmc Individual differences in executive functions are almost entirely genetic in origin
    Naomi P Friedman
    Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO 80309, USA
    J Exp Psychol Gen 137:201-25. 2008
    ....
  46. pmc Association of candidate genes with antisocial drug dependence in adolescents
    Robin P Corley
    Institute for Behavioral Genetics, University of Colorado, 447 UCB, Boulder, CO 80309, USA
    Drug Alcohol Depend 96:90-8. 2008
    ..The custom-designed SNP chip served as an effective and flexible platform for rapid interrogation of a large number of plausible candidate genes...
  47. pmc Ethnicity, body mass, and genome-wide data
    Jason D Boardman
    Institute of Behavioral Science and University of Colorado Population Center, University of Colorado, Boulder, Colorado 80309 0483, USA
    Biodemography Soc Biol 56:123-36. 2010
    ..In this case, adjusting for genetic background has no bearing on the influence of self-identified ethnicity...
  48. ncbi request reprint The role of conduct disorder in explaining the comorbidity between alcohol and illicit drug dependence in adolescence
    Tanya M M Button
    Institute for Behavioral Genetics, Campus Box 447, University of Colorado, Boulder, CO 80309, USA
    Drug Alcohol Depend 87:46-53. 2007
    ..This paper describes the result of an investigation of the extent to which comorbid alcohol and illicit drug dependence in adolescents are explained by etiological factors in common with conduct disorder...
  49. ncbi request reprint Genetic and environmental influences on conduct disorder: symptom, domain and full-scale analyses
    Heather L Gelhorn
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309 0447, USA
    J Child Psychol Psychiatry 46:580-91. 2005
    ....
  50. ncbi request reprint Dopamine transporter polymorphism associated with externalizing behavior problems in children
    Susan E Young
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA
    Am J Med Genet 114:144-9. 2002
    ..001) and 7 years (P=0.02). Although the effect size was negligible at age 9 (P=0.92), a formal test of the developmental decrease in effect across the three ages was non-significant (P=0.70)...
  51. ncbi request reprint Monoamine oxidase A (MAOA) and antisocial behaviors in the presence of childhood and adolescent maltreatment
    Brett C Haberstick
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309 0447, USA
    Am J Med Genet B Neuropsychiatr Genet 135:59-64. 2005
    ..There was, however, a non-significant trend in the predicted direction. Additional studies will be needed before firm conclusions can be drawn about this hypothesized genotype-environment interaction...
  52. ncbi request reprint Genetic influences on vulnerability to, and protective factors for, adolescent drinking
    Elizabeth A Siewert
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309 0447, USA
    Twin Res 7:617-25. 2004
    ..We propose that adolescent alcohol consumption needs to be understood in the context of these genetically influenced externalizing and internalizing propensities...
  53. ncbi request reprint Investigating the genetic and environmental structure of Cloninger's personality dimensions in adolescence
    Noa Heiman
    Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, Colorado 80309, USA
    Twin Res 7:462-70. 2004
    ..We found moderate heritability estimates for NS, HA and RD ranging from .28 to .36--with no evidence for sex-limitation in those influences...
  54. ncbi request reprint Factor structure and concurrent validity of the Drug Use Screening Inventory in a community adolescent sample
    Elizabeth A Siewert
    Institute of Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
    Addict Behav 29:627-38. 2004
    ..The resulting set of six subscales shows adequate internal consistency and provides an easily interpretable research tool for investigating etiological relationships between substance use problems and other risk behaviors...
  55. ncbi request reprint The validity of the Neale and Kendler model-fitting approach in examining the etiology of comorbidity
    Soo Hyun Rhee
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA
    Behav Genet 34:251-65. 2004
    ..As suggested by Neale and Kendler, the model-fitting approach can be applied to both unselected and selected data and to both twin and family data...
  56. ncbi request reprint Genetic and environmental analysis of behavioral risk factors for adolescent drug use in a community twin sample
    Elizabeth A Siewert
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309 0447, USA
    Twin Res 6:490-6. 2003
    ....
  57. ncbi request reprint Genetic and environmental influences on substance initiation, use, and problem use in adolescents
    Soo Hyun Rhee
    Department of Psychology and the Institute for Behavioral Genetics, University of Colorado at Boulder, 90309, USA
    Arch Gen Psychiatry 60:1256-64. 2003
    ..We conducted a sibling/twin/adoption study of substance initiation, use, and problem use, estimating the relative contribution of genetic and environmental influences on these phenotypes in adolescents...
  58. ncbi request reprint Investigating age differences in the genetic and environmental structure of the tridimensional personality questionnaire in later adulthood
    Noa Heiman
    Institute for Behavioral Genetics, University of Colorado, Boulder, USA
    Behav Genet 33:171-80. 2003
    ..For HA, RD, and PS there were no significant age-related differences in total variance. However, for NS we observed a decline in total phenotypic variance across age cohorts...
  59. ncbi request reprint Sibling-based association analyses of the serotonin transporter polymorphism and internalizing behavior problems in children
    Susan E Young
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309, USA
    J Child Psychol Psychiatry 44:961-7. 2003
    ..However, the specific genetic mechanisms responsible for this risk have not yet been identified...
  60. ncbi request reprint The validity of analyses testing the etiology of comorbidity between two disorders: comparisons of disorder prevalences in families
    Soo Hyun Rhee
    Department of Psychology, Institute for Behavioral Genetics, Campus Box 447, University of Colorado, Boulder, Colorado 80309, USA
    Behav Genet 33:257-69. 2003
    ....
  61. ncbi request reprint A genome-wide search for quantitative trait loci influencing substance dependence vulnerability in adolescence
    Michael C Stallings
    Institute for Behavioral Genetics, University of Colorado, Campus Box 447, Boulder, CO 80309 0447, USA
    Drug Alcohol Depend 70:295-307. 2003
    ..2. Multipoint mapping corroborated two locations and provided preliminary evidence for linkage to regions on chromosome 3q24-25 (near markers D3S1279 and D3S1614) and chromosome 9q34 (near markers D9S1826 and D9S1838)...
  62. ncbi request reprint The validity of analyses testing the etiology of comorbidity between two disorders: a review of family studies
    Soo Hyun Rhee
    Institute for Behavioral Genetics, University of Colorado, Boulder 80309, USA
    J Child Psychol Psychiatry 44:612-36. 2003
    ..Unfortunately, the conclusions of family studies using these two methods have been conflicting. In the present study, we examined the validity of family prevalence analyses in testing alternative comorbidity models...
  63. ncbi request reprint Testing hypotheses regarding the causes of comorbidity: examining the underlying deficits of comorbid disorders
    Soo Hyun Rhee
    Department of Psychology, University of Colorado, Boulder, CO 80309, USA
    J Abnorm Psychol 114:346-62. 2005
    ..The ability to distinguish the correct model decreased as the sample size and the correlation between the underlying deficits and the symptom scores decreased, suggesting that the issue of power should be considered carefully...
  64. ncbi request reprint Family-based association test of the 5HTTLPR and aggressive behavior in a general population sample of children
    Brett C Haberstick
    Institute of Behavioral Genetics, University of Colorado at Boulder, Boulder, Colorado, USA
    Biol Psychiatry 59:836-43. 2006
    ..Despite the fact that variation in the 5HT system has long been implicated in the etiology of aggressive behaviors, only a few association-based studies with mixed results have been reported...
  65. ncbi request reprint Comorbidity between alcohol dependence and illicit drug dependence in adolescents with antisocial behavior and matched controls
    Soo Hyun Rhee
    Institute for Behavioral Genetics, Campus Box 447, University of Colorado, Boulder, CO 80309, USA
    Drug Alcohol Depend 84:85-92. 2006
    ..Discrepancies in results may reflect different analytical approaches or differences in the samples. Here, we examine the causes of comorbidity between alcohol dependence and illicit drug dependence in adolescents...
  66. ncbi request reprint Genes and developmental stabiltiy of aggressive behavior problems at home and school in a community sample of twins aged 7-12
    Brett C Haberstick
    Institute of Behavioral Genetics, University of Colorado at Boulder, Campus Box 447, Boulder, Colorado 80309 0447, USA
    Behav Genet 36:809-19. 2006
    ..Developmentally stable levels of aggressive behavior result from genetic influences common to all ages and individual environmental influences whose effects persist across ages...
  67. ncbi request reprint A genome-wide search for quantitative trait Loci that influence antisocial drug dependence in adolescence
    Michael C Stallings
    Institute for Behavioral Genetics and Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, 80309 0444, USA
    Arch Gen Psychiatry 62:1042-51. 2005
    ..Previously we reported 2 chromosomal regions (3q24-3q25 and 9q34) likely to contain genes that influence substance dependence vulnerability (DV) in adolescence...
  68. ncbi request reprint Genetic and environmental vulnerabilities underlying adolescent substance use and problem use: general or specific?
    Susan E Young
    Institute for Behavioral Genetics, University of Colorado, 447 UCB, Boulder, CO 80303, USA
    Behav Genet 36:603-15. 2006
    ..Our results suggest that tobacco, alcohol, and marijuana problem use are mediated by common genetic influences, but shared environmental influences may be more substance-specific for problem use...
  69. ncbi request reprint Examination of the causes of covariation between conduct disorder symptoms and vulnerability to drug dependence
    Tanya M M Button
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309 0447, USA
    Twin Res Hum Genet 9:38-45. 2006
    ..Therefore, there appears to be pleiotropic genetic influence on CD symptoms and dependence vulnerability...
  70. ncbi request reprint An association between the DAT1 polymorphism and smoking behavior in young adults from the National Longitudinal Study of Adolescent Health
    David S Timberlake
    Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO 80309 0447, USA
    Health Psychol 25:190-7. 2006
    ..Never smokers and current nonsmokers had an excess transmission of the 9-repeat allele compared with regular smokers, suggesting a protective effect of the 9-repeat allele, which is hypothesized to alter synaptic dopamine levels...
  71. ncbi request reprint Relationship between adolescent marijuana use and young adult illicit drug use
    Jeffrey M Lessem
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309 0447, USA
    Behav Genet 36:498-506. 2006
    ..Shared environmental factors mediated much of the relationship between adolescent marijuana use and young adult drug use. The association remained, however, even when controlling for familial environmental and other measured factors...
  72. ncbi request reprint Genetic and environmental contributions to common psychopathologies of childhood and adolescence: a study of twins and their siblings
    Marissa A Ehringer
    Institute for Behavioral Genetics, University of Colorado at Boulder, 80309, USA
    J Abnorm Child Psychol 34:1-17. 2006
    ..We found evidence for both genetic and non-shared environmental influences for all disorders. Shared environmental influences also seem to be important for MDD and lifetime GAD...
  73. ncbi request reprint The moderating effects of religiosity on the genetic and environmental determinants of smoking initiation
    David S Timberlake
    Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309 0447, USA
    Nicotine Tob Res 8:123-33. 2006
    ..Although all three measures of religiosity were associated with lower rates of smoking initiation, only self-rated religiousness moderated genetic influences on the liability for smoking...
  74. ncbi request reprint Not all executive functions are related to intelligence
    Naomi P Friedman
    Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO 80309, USA
    Psychol Sci 17:172-9. 2006
    ....
  75. ncbi request reprint College attendance and its effect on drinking behaviors in a longitudinal study of adolescents
    David S Timberlake
    Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado, USA
    Alcohol Clin Exp Res 31:1020-30. 2007
    ..We first tested for changes in alcohol consumption in adolescents who did and did not subsequently attend college, and then tested for variation of the genetic and environmental determinants of drinking in these 2 groups...
  76. ncbi request reprint Test of association between TaqIA A1 allele and alcohol use disorder phenotypes in a sample of adolescent patients with serious substance and behavioral problems
    Joseph T Sakai
    Department of Psychiatry, Division of Substance Dependence, University of Colorado School of Medicine, Denver, CO 80262, USA
    Drug Alcohol Depend 88:130-7. 2007
    ....
  77. pmc A genome-wide scan for loci influencing adolescent cannabis dependence symptoms: evidence for linkage on chromosomes 3 and 9
    Christian J Hopfer
    Division of Substance Dependence, University of Colorado School of Medicine, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Drug Alcohol Depend 89:34-41. 2007
    ..Genetic risk factors account for part of the variation in the development of cannabis dependence symptoms; however, no linkage studies have been performed for cannabis dependence symptoms. This study aimed to identify such loci...
  78. ncbi request reprint Family transmission of marijuana use, abuse, and dependence
    Christian J Hopfer
    University of Colorado Health Sciences Center, Denver 80262, USA
    J Am Acad Child Adolesc Psychiatry 42:834-41. 2003
    ..To examine the familial aggregation of marijuana use, abuse, and dependence...
  79. pmc Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents
    Christian J Hopfer
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Med Genet B Neuropsychiatr Genet 141:895-901. 2006
    ..Our findings provide evidence suggesting that a common CNR1 haplotype is associated with developing fewer cannabis dependence symptoms among adolescents who have experimented with cannabis...
  80. ncbi request reprint Review of twin and adoption studies of adolescent substance use
    Christian J Hopfer
    Division of Substance Dependence, Department of Psychiatry, University of Colorado Health Sciences Center, Denver, USA
    J Am Acad Child Adolesc Psychiatry 42:710-9. 2003
    ..To review studies of adolescent substance use and abuse with genetically informative designs...
  81. pmc Genetic and environmental contributions to general cognitive ability through the first 16 years of life
    Stephen A Petrill
    Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA 16802, USA
    Dev Psychol 40:805-12. 2004
    ..Modeling results suggested that genetic factors mediated phenotypic stability throughout this entire period, whereas most age-to-age instability appeared to be due to nonshared environmental influences...
  82. ncbi request reprint Genetic and shared environmental influences on children's 24-h food and beverage intake: sex differences at age 7 y
    Myles S Faith
    Center for Weight and Eating Disorders, University of Pennsylvania School of Medicine and the The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Am J Clin Nutr 87:903-11. 2008
    ..The genetics of habitual food and beverage intake in early childhood is poorly understood...
  83. ncbi request reprint Case-control and within-family tests for association between 5HTTLPR and conduct problems in a longitudinal adolescent sample
    Joseph T Sakai
    Division of Substance Dependence, Department of Psychiatry, University of Colorado School of Medicine, Denver CO 80262, USA
    Psychiatr Genet 17:207-14. 2007
    ..Using a large general population sample, we sought to test for an association between 5HTTLPR and conduct problems, and to explore for a possible 5HTTLPR by maltreatment interaction...
  84. ncbi request reprint Setting priorities for genomic research
    Wade Berrettini
    Science 304:1445-7; author reply 1445-7. 2004
  85. ncbi request reprint Genetic influences on quantity of alcohol consumed by adolescents and young adults
    Christian J Hopfer
    Department of Psychiatry, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Box C 268 35, Denver, CO 80262, USA
    Drug Alcohol Depend 78:187-93. 2005
    ..To examine genetic and environmental influences on drinking in a nationally representative study of genetically informative adolescents followed into young adulthood...