Steve Hernandez

Summary

Affiliation: University of Texas Health Science Center
Country: USA

Publications

  1. pmc Caspofungin resistance in Candida albicans: correlating clinical outcome with laboratory susceptibility testing of three isogenic isolates serially obtained from a patient with progressive Candida esophagitis
    Steve Hernandez
    Department of Medicine, Division Infectious Diseases 7881, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Antimicrob Agents Chemother 48:1382-3. 2004
  2. ncbi request reprint Alternatives to amphotericin B for Candida rugosa infection
    Steve Hernandez
    Department of Medicine, Division of Infectious Diseases, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    J Antimicrob Chemother 54:477-80. 2004
  3. pmc Addition of caspofungin to fluconazole does not improve outcome in murine candidiasis
    John R Graybill
    The University of Texas Health Science Center at San Antonio, Department of Medicine, San Antonio, Texas 78229 3900, USA
    Antimicrob Agents Chemother 47:2373-5. 2003
  4. pmc Activity of posaconazole combined with amphotericin B against Aspergillus flavus infection in mice: comparative studies in two laboratories
    Laura K Najvar
    Department of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Antimicrob Agents Chemother 48:758-64. 2004
  5. pmc Caspofungin and liposomal amphotericin B therapy of experimental murine scedosporiosis
    Rosie Bocanegra
    The University of Texas Health Science Center at San Antonio, Department of Medicine Division of Infectious Diseases MC 7881, 7703 Floyd Curl Drive, San Antonio, Texas 78229 3900, USA
    Antimicrob Agents Chemother 49:5139-41. 2005
  6. ncbi request reprint Improving the mouse model for studying the efficacy of voriconazole
    John R Graybill
    The University of Texas Health Science Center at San Antonio, Department of Medicine, Division of Infectious Diseases 7881, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    J Antimicrob Chemother 51:1373-6. 2003
  7. pmc Antifungal therapy of murine Aspergillus terreus infection
    John R Graybill
    The University of Texas Health Science Center at San Antonio, Department of Medicine, Division of Infectious Diseases mail code 7881, 7703 Floyd Curl Dr, San Antonio, TX 78229 3900, USA
    Antimicrob Agents Chemother 48:3715-9. 2004

Collaborators

Detail Information

Publications7

  1. pmc Caspofungin resistance in Candida albicans: correlating clinical outcome with laboratory susceptibility testing of three isogenic isolates serially obtained from a patient with progressive Candida esophagitis
    Steve Hernandez
    Department of Medicine, Division Infectious Diseases 7881, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Antimicrob Agents Chemother 48:1382-3. 2004
    ..We concluded that there is a correlation between in vivo failure and rising in vitro caspofungin MICs...
  2. ncbi request reprint Alternatives to amphotericin B for Candida rugosa infection
    Steve Hernandez
    Department of Medicine, Division of Infectious Diseases, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    J Antimicrob Chemother 54:477-80. 2004
    ..We evaluated amphotericin B, fluconazole, posaconazole and voriconazole as alternative treatments against infection in mice with two isolates of C. rugosa...
  3. pmc Addition of caspofungin to fluconazole does not improve outcome in murine candidiasis
    John R Graybill
    The University of Texas Health Science Center at San Antonio, Department of Medicine, San Antonio, Texas 78229 3900, USA
    Antimicrob Agents Chemother 47:2373-5. 2003
    ..However, caspofungin is not 100% curative in candidiasis. Therefore, we evaluated combinations of fluconazole with caspofungin for murine candidemia. We could not show any benefit of combined therapy over individual antifungal drugs...
  4. pmc Activity of posaconazole combined with amphotericin B against Aspergillus flavus infection in mice: comparative studies in two laboratories
    Laura K Najvar
    Department of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Antimicrob Agents Chemother 48:758-64. 2004
    ..These studies do not confirm the antagonistic interaction of triazoles and polyenes reported by others...
  5. pmc Caspofungin and liposomal amphotericin B therapy of experimental murine scedosporiosis
    Rosie Bocanegra
    The University of Texas Health Science Center at San Antonio, Department of Medicine Division of Infectious Diseases MC 7881, 7703 Floyd Curl Drive, San Antonio, Texas 78229 3900, USA
    Antimicrob Agents Chemother 49:5139-41. 2005
    ..Amphotericin B and caspofungin were each effective, but combined therapy did not appear to offer advantages over liposomal amphotericin B alone...
  6. ncbi request reprint Improving the mouse model for studying the efficacy of voriconazole
    John R Graybill
    The University of Texas Health Science Center at San Antonio, Department of Medicine, Division of Infectious Diseases 7881, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    J Antimicrob Chemother 51:1373-6. 2003
    ..The mechanism may be inhibition of gut mucosal cytochrome enzymes that rapidly degrade voriconazole in the mouse. These murine studies support expansion of voriconazole therapy in other highly resistant systemic mycoses...
  7. pmc Antifungal therapy of murine Aspergillus terreus infection
    John R Graybill
    The University of Texas Health Science Center at San Antonio, Department of Medicine, Division of Infectious Diseases mail code 7881, 7703 Floyd Curl Dr, San Antonio, TX 78229 3900, USA
    Antimicrob Agents Chemother 48:3715-9. 2004
    ..Caspofungin and posaconazole both appeared beneficial and may be reasonable treatment alternatives for infection with A. terreus...