Bin He

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. ncbi request reprint An equivalent current source model and laplacian weighted minimum norm current estimates of brain electrical activity
    Bin He
    Department of Bioengineering, The University of Illinois at Chicago, 60607, USA
    IEEE Trans Biomed Eng 49:277-88. 2002
  2. ncbi request reprint A spline Laplacian ECG estimator in a realistic geometry volume conductor
    Bin He
    Department of Bioengineering and Electrical and Computer Engineering, University of Illinois at Chicago, 60607, USA
    IEEE Trans Biomed Eng 49:110-7. 2002
  3. ncbi request reprint Imaging and visualization of 3-D cardiac electric activity
    B He
    Department of Bioengineering, University of Illinois at Chicago, 60607, USA
    IEEE Trans Inf Technol Biomed 5:181-6. 2001
  4. ncbi request reprint Noninvasive imaging of cardiac transmembrane potentials within three-dimensional myocardium by means of a realistic geometry anisotropic heart model
    Bin He
    University of Illinois at Chicago, SEO 218, M C 063, 851 S Morgan Street, Chicago, IL 60607, USA
    IEEE Trans Biomed Eng 50:1190-202. 2003
  5. ncbi request reprint High-resolution EEG: a new realistic geometry spline Laplacian estimation technique
    B He
    Department of Electrical Engineering and Computer Science, University of Illinois at Chicago, MC 154, SEO 1120, 851 Morgan Street, Chicago IL 60607, USA
    Clin Neurophysiol 112:845-52. 2001
  6. ncbi request reprint Noninvasive three-dimensional activation time imaging of ventricular excitation by means of a heart-excitation model
    Bin He
    The University of Illinois at Chicago, Department of Bioengineering, 60607, USA
    Phys Med Biol 47:4063-78. 2002
  7. ncbi request reprint High-resolution spatio-temporal functional neuroimaging of brain activity
    B He
    Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois 60607, USA
    Crit Rev Biomed Eng 30:283-306. 2002
  8. ncbi request reprint A cortical potential imaging analysis of the P300 and novelty P3 components
    B He
    Department of Bioengineering, University of Illinois at Chicago, USA
    Hum Brain Mapp 12:120-30. 2001
  9. ncbi request reprint Estimating cortical potentials from scalp EEG's in a realistically shaped inhomogeneous head model by means of the boundary element method
    B He
    Department of Electrical Engineering and Computer Science, University of Illinois, Chicago 60607, USA
    IEEE Trans Biomed Eng 46:1264-8. 1999
  10. ncbi request reprint Body surface Laplacian mapping of bioelectrical activity
    B He
    Department of Electrical Engineering and Computer Science, University of Illinois at Chicago, USA
    Methods Inf Med 36:326-8. 1997

Collaborators

Detail Information

Publications104 found, 100 shown here

  1. ncbi request reprint An equivalent current source model and laplacian weighted minimum norm current estimates of brain electrical activity
    Bin He
    Department of Bioengineering, The University of Illinois at Chicago, 60607, USA
    IEEE Trans Biomed Eng 49:277-88. 2002
    ..These results highlight the advantages of the equivalent current source imaging and suggest that it may become an alternative approach to imaging spatially distributed current sources-sinks in the brain and other organ systems...
  2. ncbi request reprint A spline Laplacian ECG estimator in a realistic geometry volume conductor
    Bin He
    Department of Bioengineering and Electrical and Computer Engineering, University of Illinois at Chicago, 60607, USA
    IEEE Trans Biomed Eng 49:110-7. 2002
    ....
  3. ncbi request reprint Imaging and visualization of 3-D cardiac electric activity
    B He
    Department of Bioengineering, University of Illinois at Chicago, 60607, USA
    IEEE Trans Inf Technol Biomed 5:181-6. 2001
    ..In summary, the present computer simulation suggests that the proposed 3-D cardiac current source imaging and localization approach appears to be a promising candidate for localizing and imaging sites of origins of cardiac activation...
  4. ncbi request reprint Noninvasive imaging of cardiac transmembrane potentials within three-dimensional myocardium by means of a realistic geometry anisotropic heart model
    Bin He
    University of Illinois at Chicago, SEO 218, M C 063, 851 S Morgan Street, Chicago, IL 60607, USA
    IEEE Trans Biomed Eng 50:1190-202. 2003
    ....
  5. ncbi request reprint High-resolution EEG: a new realistic geometry spline Laplacian estimation technique
    B He
    Department of Electrical Engineering and Computer Science, University of Illinois at Chicago, MC 154, SEO 1120, 851 Morgan Street, Chicago IL 60607, USA
    Clin Neurophysiol 112:845-52. 2001
    ..A new realistic geometry (RG) spline Laplacian estimation technique has been developed for high-resolution EEG imaging...
  6. ncbi request reprint Noninvasive three-dimensional activation time imaging of ventricular excitation by means of a heart-excitation model
    Bin He
    The University of Illinois at Chicago, Department of Bioengineering, 60607, USA
    Phys Med Biol 47:4063-78. 2002
    ....
  7. ncbi request reprint High-resolution spatio-temporal functional neuroimaging of brain activity
    B He
    Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois 60607, USA
    Crit Rev Biomed Eng 30:283-306. 2002
    ..The remaining challenges, future trends, and potential applications of the high-resolution functional neuroimaging research are discussed...
  8. ncbi request reprint A cortical potential imaging analysis of the P300 and novelty P3 components
    B He
    Department of Bioengineering, University of Illinois at Chicago, USA
    Hum Brain Mapp 12:120-30. 2001
    ..These analyses show how the CPI can be used to relate the scalp electrical recordings to the underlying brain activity...
  9. ncbi request reprint Estimating cortical potentials from scalp EEG's in a realistically shaped inhomogeneous head model by means of the boundary element method
    B He
    Department of Electrical Engineering and Computer Science, University of Illinois, Chicago 60607, USA
    IEEE Trans Biomed Eng 46:1264-8. 1999
    ..The present study demonstrates that the cortical potentials can be directly estimated from the scalp potentials using the BEM in a realistically shaped inhomogeneous head model...
  10. ncbi request reprint Body surface Laplacian mapping of bioelectrical activity
    B He
    Department of Electrical Engineering and Computer Science, University of Illinois at Chicago, USA
    Methods Inf Med 36:326-8. 1997
    ..The present investigation suggests body surface Laplacian mapping provides an important means in interpreting bioelectrical signals...
  11. ncbi request reprint High-resolution EEG: on the cortical equivalent dipole layer imaging
    Bin He
    Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA
    Clin Neurophysiol 113:227-35. 2002
    ..Several cortical imaging approaches, such as the epicortical potentials and a dipole layer accounting for the cortical activity, have been used to represent brain electrical activity...
  12. pmc Dephosphorylation of eIF2alpha mediated by the gamma134.5 protein of herpes simplex virus 1 facilitates viral neuroinvasion
    Dustin Verpooten
    Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois 60612, USA
    J Virol 83:12626-30. 2009
    ..5 abrogate viral replication in the eye and spread to the trigeminal ganglia and brain. Intriguingly, inhibition of antiviral gene induction by gamma(1)34.5 is not sufficient to exhibit viral virulence...
  13. pmc The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide
    Huali Jin
    Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, IL 60612, USA
    J Gen Virol 91:352-61. 2010
    ..Our work highlights a critical role of VP35 in viral interference in DC function with resultant deficiency in T-cell function, which may contribute to the profound virulence of Ebola virus infection...
  14. pmc Inhibition of TANK binding kinase 1 by herpes simplex virus 1 facilitates productive infection
    Yijie Ma
    Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois, USA
    J Virol 86:2188-96. 2012
    ..5 null mutant. Therefore, in addition to PKR, γ(1)34.5 negatively regulates TBK1, which contributes viral replication and spread in vivo...
  15. pmc Galanin fiber hyperinnervation preserves neuroprotective gene expression in cholinergic basal forebrain neurons in Alzheimer's disease
    Scott E Counts
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    J Alzheimers Dis 18:885-96. 2009
    ..Hence, GAL fiber hyperinnervation appears to preserve the expression of genes subserving multiple neuroprotective pathways suggesting that GAL overexpression regulates CBF neuron survival in AD...
  16. ncbi request reprint Noninvasive localization of the site of origin of paced cardiac activation in human by means of a 3-D heart model
    Guanglin Li
    Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA
    IEEE Trans Biomed Eng 50:1117-20. 2003
    ..The heart-model-based localization approach may become an alternative tool in localizing the site of origin of cardiac activation...
  17. ncbi request reprint Body surface Laplacian electrocardiogram of ventricular depolarization in normal human subjects
    Guanglin Li
    Department of Bioengineering, The University of Illinois at Chicago, Illinois 60607, USA
    J Cardiovasc Electrophysiol 14:16-27. 2003
    ..The aim of the present study was to explore the relationship between the Laplacian ECG and the underlying cardiac activities during ventricular depolarization in healthy human subjects...
  18. pmc Activation of NF-κB in CD8+ dendritic cells Ex Vivo by the γ134.5 null mutant correlates with immunity against herpes simplex virus 1
    Huali Jin
    Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois, USA
    J Virol 86:1059-68. 2012
    ..These results suggest that engagement of the γ(1)34.5 null mutant with CD8(+) DCs elicits innate immunity to activate NF-κB, which translates into protective immunity...
  19. pmc A herpesvirus virulence factor inhibits dendritic cell maturation through protein phosphatase 1 and Ikappa B kinase
    Huali Jin
    Department of Microbiology and Immunology M C 790, College of Medicine, University of Illinois, Chicago, 835 South Wolcott Avenue, Chicago, IL 60612, USA
    J Virol 85:3397-407. 2011
    ..Deletions or mutations in either domain abolish the activity of γ(1)34.5. These results suggest that the control of IκB kinase dephosphorylation by γ(1)34.5 represents a critical viral mechanism to disrupt dendritic cell functions...
  20. pmc Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease
    Elliott J Mufson
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    J Neuropathol Exp Neurol 71:1018-29. 2012
    ..These findings suggest that alterations in the hippocampal NGF signaling pathway in MCI and AD favor proNGF-mediated proapoptotic pathways, and that this is independent of Aβ accumulation during AD progression...
  21. ncbi request reprint An efficient rhythmic component expression and weighting synthesis strategy for classifying motor imagery EEG in a brain-computer interface
    Tao Wang
    Department of Bioengineering, University of Illinois at Chicago, IL 60607, USA
    J Neural Eng 1:1-7. 2004
    ..The present promising results suggest that the present classification algorithm can be used in initiating a general-purpose mental state recognition based on motor imagery tasks...
  22. ncbi request reprint Genomic expression discovery predicts pathways and opposing functions behind phenotypes
    Hassan M Fathallah-Shaykh
    Department of Neurological Sciences and Neurosurgery, Rush Presbyterian S Luke s Medical Center, Chicago, Illinois 60612, USA
    J Biol Chem 278:23830-3. 2003
    ..The findings expose interconnected genes and propose a role of genomic expression discovery in functional genomics of living systems...
  23. pmc Control of TANK-binding kinase 1-mediated signaling by the gamma(1)34.5 protein of herpes simplex virus 1
    Dustin Verpooten
    Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, Illinois 60612, USA
    J Biol Chem 284:1097-105. 2009
    ..Hence, control of TBK1-mediated cell signaling by the gamma(1)34.5 protein contributes to herpes simplex virus infection. These results reveal that TBK1 plays a pivotal role in limiting replication of a DNA virus...
  24. ncbi request reprint Estimation of noise level and signal to noise ratio of laplacian electrocardiogram during ventricular depolarization and repolarization
    Jie Lian
    Department of Bioengineering, University of Illinois at Chicago, 60607, USA
    Pacing Clin Electrophysiol 25:1474-87. 2002
    ....
  25. pmc Hippocampal drebrin loss in mild cognitive impairment
    Scott E Counts
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Ill 60612, USA
    Neurodegener Dis 10:216-9. 2012
    ..This differential alteration of synaptic markers in MCI suggests a selective impairment in hippocampal postsynaptic dendritic plasticity in prodromal AD that likely heralds the onset of memory impairment in symptomatic disease...
  26. pmc Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease
    Scott E Counts
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Ill 60612, USA
    Neurodegener Dis 5:228-31. 2008
    ..Fibers containing galanin (GAL) enlarge and hyperinnervate cholinergic basal forebrain (CBF) nucleus basalis (NB) neurons in late-stage Alzheimer's disease (AD), yet the physiological consequences of this phenomenon are unclear...
  27. pmc The VP35 protein of Ebola virus inhibits the antiviral effect mediated by double-stranded RNA-dependent protein kinase PKR
    Zongdi Feng
    Department of Microbiology and Immunology M C 790, College of Medicine, The University of Illinois at Chicago, 835 South Wolcott Avenue, Chicago, IL 60612, USA
    J Virol 81:182-92. 2007
    ..Together, these results show that the VP35 protein targets multiple pathways of the interferon system...
  28. ncbi request reprint Spatial resolution of body surface potential and Laplacian pace mapping
    Guanglin Li
    Department of Bioengineering, University of Illinois at Chicago, USA
    Pacing Clin Electrophysiol 25:420-9. 2002
    ....
  29. pmc Mathematical algorithm for discovering states of expression from direct genetic comparison by microarrays
    Hassan M Fathallah-Shaykh
    Department of Neurological Sciences, Section of Neuro Oncology, Rush University Medical Center, 1725 West Harrison Street, Chicago, IL 60612, USA
    Nucleic Acids Res 32:3807-14. 2004
    ..The false discovery rates are significantly lower than other methods. The discovered states of genetic expression facilitate functional discovery and are validated by real-time RT-PCR. Better quality improves sensitivity...
  30. pmc Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in Alzheimer's disease
    Sylvia E Perez
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Pathol 180:526-40. 2012
    ..These data suggest that Rac1b expression acts as a modulator or transducer of various signaling pathways that lead to NFT formation and membrane dysfunction in a subgroup of CBF NB neurons in AD...
  31. pmc Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice
    Sylvia E Perez
    Department of Neurological Sciences, Rush University Medical Center, 1735 West Harrison Street, Suite 300, Chicago, IL 60612, USA
    Neurobiol Dis 41:338-52. 2011
    ..These data demonstrate that cholinotrophic alterations in 3xTg-AD mice are age- and gender-dependent and more pronounced in the hippocampus, a structure more severely affected by Aβ plaque pathology...
  32. pmc The gamma 1 34.5 protein of herpes simplex virus 1 is required to interfere with dendritic cell maturation during productive infection
    Huali Jin
    Department of Microbiology and Immunology, College of Medicine, The University of Illinois at Chicago, 835 South Wolcott Ave, Chicago, IL 60612, USA
    J Virol 83:4984-94. 2009
    ..These data indicate that gamma(1)34.5 is involved in the impairment of innate immunity by inhibiting both type I interferon production and DC maturation, leading to defective T-cell activation...
  33. ncbi request reprint Classifying EEG-based motor imagery tasks by means of time-frequency synthesized spatial patterns
    Tao Wang
    University of Illinois at Chicago, Chicago, IL, USA
    Clin Neurophysiol 115:2744-53. 2004
    ....
  34. ncbi request reprint A self-coherence enhancement algorithm and its application to enhancing three-dimensional source estimation from EEGs
    D Yao
    Department of Bioengineering, The University of Illinois at Chicago, 60607, USA
    Ann Biomed Eng 29:1019-27. 2001
    ..Computer simulation studies have been conducted to evaluate the performance of the SCEA and to compare its performance to that of the LORETA and the FOCUSS algorithms...
  35. ncbi request reprint Motor imagery task classification for brain computer interface applications using spatiotemporal principle component analysis
    Anirudh Vallabhaneni
    Department of Bioengineering, University of Illinois at Chicago, IL, USA
    Neurol Res 26:282-7. 2004
    ..The present approach has yielded good classification results and promises to have potential for further refinement for increased accuracy as well as application in online brain computer interface (BCI)...
  36. pmc DHA diet reduces AD pathology in young APPswe/PS1 Delta E9 transgenic mice: possible gender effects
    Sylvia E Perez
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Neurosci Res 88:1026-40. 2010
    ..Finally, in vitro DHA treatment prevented amyloid toxicity in cell cultures. Our findings support the concept that increased DHA consumption may play and important role in reducing brain insults in female AD patients...
  37. ncbi request reprint Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease
    Scott E Counts
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Arch Neurol 64:1771-6. 2007
    ..Although alterations in these AChRs occur in the AD cortex, there is little information detailing whether defects in nAChR and mAChR gene expression occur in cholinergic NB neurons during disease progression...
  38. ncbi request reprint Localization of the site of origin of cardiac activation by means of a heart-model-based electrocardiographic imaging approach
    G Li
    University of Illinois at Chicago, Department of EECS, 60607, USA
    IEEE Trans Biomed Eng 48:660-9. 2001
    ....
  39. ncbi request reprint High-resolution EEG: cortical potential imaging of interictal spikes
    X Zhang
    Department of Bioengineering, The University of Illinois at Chicago, MC 063, SEO 218, 851 South Morgan Street, Chicago, IL 60607, USA
    Clin Neurophysiol 114:1963-73. 2003
    ..Noninvasive localization of cortical areas associated with interictal epileptiform spikes may provide important information to facilitate presurgical planning for intractable epilepsy patients...
  40. ncbi request reprint Cortical potential imaging of episodic memory encoding
    Jie Lian
    Department of Bioengineering, University of Illinois at Chicago, USA
    Brain Topogr 15:29-36. 2002
    ..It is concluded that these regions work jointly across both spatial and temporal domains to promote verbal memory formation...
  41. ncbi request reprint A minimal product method and its application to cortical imaging
    J Lian
    Department of Bioengineering, University of Illinois at Chicago, 60607, USA
    Brain Topogr 13:209-17. 2001
    ....
  42. ncbi request reprint Viruses, endoplasmic reticulum stress, and interferon responses
    B He
    Department of Microbiology and Immunology, College of Medicine, The University of Illinois at Chicago, 835 South Wolcott Avenue, Chicago, IL 60612, USA
    Cell Death Differ 13:393-403. 2006
    ..This review highlights recent progress in these areas...
  43. ncbi request reprint Boundary element method-based cortical potential imaging of somatosensory evoked potentials using subjects' magnetic resonance images
    B He
    Department of Bioengineering, University of Illinois at Chicago, 60607, USA
    Neuroimage 16:564-76. 2002
    ....
  44. ncbi request reprint A bioelectric inverse imaging technique based on surface Laplacians
    B He
    Department of Electrical Engineering and Computer Science and Bioengineering Program, University of Illinois at Chicago 60607, USA
    IEEE Trans Biomed Eng 44:529-38. 1997
    ..The present theoretical study suggests that the Laplacian-based inverse imaging technique may have important applications to epicardial inverse imaging and other bioelectric inverse imaging...
  45. pmc Recognition of herpes simplex viruses: toll-like receptors and beyond
    Yijie Ma
    Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago, IL 60612, USA
    J Mol Biol 426:1133-47. 2014
    ..In this review, we describe recent advances pertinent to the interplay of HSV and the induction of innate immunity mediated by pathogen recognition receptors or pathways. ..
  46. ncbi request reprint Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease
    Deanna M Marchionini
    Dept Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Brain Res 1147:77-88. 2007
    ..Thus, PTN was identified as a factor that plays a role in the nigrostriatal system during development and in response to disease, and may therefore be useful for neuroprotection or reconstruction of the DA system...
  47. ncbi request reprint Non-invasive estimation of myocardial infarction by means of a heart-model-based imaging approach: a simulation study
    G Li
    Department of Bioengineering, The University of Illinois at Chicago, USA
    Med Biol Eng Comput 42:128-36. 2004
    ..The simulation results suggest the feasibility of applying the heart-model-based imaging approach to the estimation of myocardial infarction from body surface potentials...
  48. ncbi request reprint Equivalent dipole source imaging of brain electric activity by means of parametric projection filter
    J Hori
    Department of EECS, University of Illinois at Chicago, 60607, USA
    Ann Biomed Eng 29:436-45. 2001
    ..A method for determining the optimum regularization parameter, which can be applied to parametric inverse techniques, has also been developed...
  49. ncbi request reprint Body surface Laplacian mapping of atrial depolarization in healthy human subjects
    J Lian
    Department of Bioengineering, University of Illinois at Chicago, USA
    Med Biol Eng Comput 40:650-9. 2002
    ..The above findings may be directly related to the underlying activation sequence during atrial depolarization in healthy subjects, suggesting the potential clinical applications of the Laplacian ECG technique...
  50. pmc The Akt1 isoform is required for optimal IFN-β transcription through direct phosphorylation of β-catenin
    Benjamin N Gantner
    Department of Pharmacology, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Immunol 189:3104-11. 2012
    ..Taken together, these results demonstrate that the Akt1 isoform is required for β-catenin-mediated promotion of IFN-β transcription downstream of TLR3 activation...
  51. ncbi request reprint Characterization of the triplet repeats in the central domain of the gamma134.5 protein of herpes simplex virus 1
    Xianghong Jing
    Department of Microbiology and Immunology M C 790, College of Medicine, The University of Illinois at Chicago, 835 South Wolcott Avenue, Chicago, IL 60612, USA
    J Gen Virol 86:2411-9. 2005
    ..Accordingly, these mutant viruses are predominantly present within infected cells. These results indicate that deletions in the central domain of the gamma134.5 protein impair virus egress, but not virus response to interferon...
  52. pmc Herpes simplex virus 1 infection activates the endoplasmic reticulum resident kinase PERK and mediates eIF-2alpha dephosphorylation by the gamma(1)34.5 protein
    Guofeng Cheng
    Department of Microbiology and Immunology M C 790, College of Medicine, The University of Illinois at Chicago, 835 South Wolcott Ave, Chicago, IL 60612, USA
    J Virol 79:1379-88. 2005
    ..Together, these observations suggest that regulation of eIF-2alpha phosphorylation by the gamma(1)34.5 protein is an efficient way to antagonize the inhibitory activity of PKR as well as PERK during productive infection...
  53. ncbi request reprint Mathematical modeling of noise and discovery of genetic expression classes in gliomas
    Hassan M Fathallah-Shaykh
    Department of Neurological Sciences, Rush Presbyterian St Lukes Medical Center, Chicago, Illinois, IL 60612, USA
    Oncogene 21:7164-74. 2002
    ..The results yield a genetic analysis of gliomas and identify classes of genetic expression that link novel genes to the biology of gliomas...
  54. ncbi request reprint Val193 and Phe195 of the gamma 1 34.5 protein of herpes simplex virus 1 are required for viral resistance to interferon-alpha/beta
    G Cheng
    Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, 835 South Wolcott Avenue, Chicago, Illinois 60612, USA
    Virology 290:115-20. 2001
    ..These findings provide evidence that the gamma 1 34.5 protein contributes to HSV-1 resistance to interferon-alpha/beta by inhibiting PKR function...
  55. pmc AlaArg motif in the carboxyl terminus of the gamma(1)34.5 protein of herpes simplex virus type 1 is required for the formation of a high-molecular-weight complex that dephosphorylates eIF-2alpha
    G Cheng
    Department of Microbiology and Immunology, College of Medicine, The University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Virol 75:3666-74. 2001
    ..5 is functionally active in the absence of any other HSV proteins. In addition to a PP1 binding domain, the carboxyl terminus of gamma(1)34.5 contains an effector domain that is required to form a functional complex...
  56. pmc fMRI-EEG integrated cortical source imaging by use of time-variant spatial constraints
    Zhongming Liu
    Department of Biomedical Engineering, University of Minnesota, 7 105 Hasselmo Hall, 312 Church Street, Minneapolis, MN 55455, USA
    Neuroimage 39:1198-214. 2008
    ....
  57. ncbi request reprint Three-dimensional activation sequence imaging in a rabbit model
    Chengzong Han
    Department of Biomedical Engineering, University of Minnesota, USA
    Conf Proc IEEE Eng Med Biol Soc 2007:5609-11. 2007
    ..89, RE = 0.22, and LE = 6.85mm. The simulation results demonstrate that the present 3-D imaging approach has reasonable accuracy and robustness against recording noises...
  58. ncbi request reprint An adaptive directed transfer function approach for detecting dynamic causal interactions
    Christopher Wilke
    Department of Biomedical Engineering, University of Minnesota, 7 105 NHH, 312 Church Street SE, Minneapolis, MN 55455, USA
    Conf Proc IEEE Eng Med Biol Soc 2007:4949-52. 2007
    ....
  59. ncbi request reprint Evaluation of cortical imaging techniques based on somatosensory evoked potentials
    Xiaoxiao Bai
    Department of Biomedical Engineering, University of Minnesota, 312 Church Street, Minneapolis, MN 55455, USA
    Conf Proc IEEE Eng Med Biol Soc 1:1000-1. 2006
    ..The present results suggest that L(1)-norm methods gave the most accurate results in terms of cortical current density imaging of brain responses invoked by somatosensory stimulation...
  60. ncbi request reprint A new multimodal imaging strategy for integrating fMRI with EEG
    Zhongming Liu
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA
    Conf Proc IEEE Eng Med Biol Soc 1:859-62. 2006
    ..The proposed Twomey approach may make an important contribution to the multimodal neuroimaging integrating fMRI with EEG...
  61. ncbi request reprint Cortical potential imaging of movement-related potentials using parametric Wiener filter in realistic-shaped head model
    Junichi Hori
    Dept of Biocybern, Niigata Univ
    Conf Proc IEEE Eng Med Biol Soc 1:3662-5. 2006
    ..The proposed methods demonstrated that the contralateral premotor cortex was preponderantly activated In relation to movement performance...
  62. ncbi request reprint Estimation of cortical dipole sources by equivalent dipole layer imaging and independent component analysis
    Naotoshi Aoki
    Department of Biocybernetics, Niigata University, Niigata, Japan
    Conf Proc IEEE Eng Med Biol Soc 1:992-5. 2006
    ..The present simulation results indicated that the equivalent dipole sources was accurately estimated by ICA and dipole imaging. We also applied the proposed method to human visual evoked potential...
  63. ncbi request reprint Three-dimensional cardiac electrical imaging from intracavity recordings
    Bin He
    University of Minnesota, Department of Biomedical Engineering, 7 105 NHH, 312 Church Street SE, Minneapolis, MN 55455, USA
    IEEE Trans Biomed Eng 54:1454-60. 2007
    ..The application of this inverse method has the potential of enhancing electrocardiographic mapping by catheters in electrophysiology laboratories, aiding cardiac resynchronization therapy, and other clinical applications...
  64. ncbi request reprint Localization of the site of origin of reentrant arrhythmia from body surface potential maps: a model study
    Chenguang Liu
    Department of Biomedical Engineering, University of Minnesota, 7 105 BSBE, 312 Church St, Minneapolis, MN 55455, USA
    Phys Med Biol 50:1421-32. 2005
    ..The present simulation study suggests the feasibility of localizing the site of origin of reentrant arrhythmia from non-invasive BSPMs, with the aid of a cardiac arrhythmia model...
  65. pmc Estimation of global ventricular activation sequences by noninvasive three-dimensional electrical imaging: validation studies in a Swine model during pacing
    Chenguang Liu
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Cardiovasc Electrophysiol 19:535-40. 2008
    ..The aim of the present study was to validate the 3DCEI in an intact large mammalian model (swine) during acute ventricular pacing...
  66. ncbi request reprint Equivalent physical models and formulation of equivalent source layer in high-resolution EEG imaging
    Dezhong Yao
    School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu City, 610054, Sichuan Province, People s Republic of China
    Phys Med Biol 48:3475-83. 2003
    ..Based on these equivalent physical models, closed solutions of ECL and EDL corresponding to a dipole enclosed by a spherical layer are given. These results provide the theoretical basis of ESL applications in high-resolution EEG mapping...
  67. ncbi request reprint Statistical accuracy of a moving equivalent dipole method to identify sites of origin of cardiac electrical activation
    Antonis A Armoundas
    Massachusetts Institute of Technology, E25 335, 77 Massachusetts Ave, Cambridge, MA 02139, USA
    IEEE Trans Biomed Eng 50:1360-70. 2003
    ..In conclusion, our algorithm to estimate the SEMD parameters from body surface ECG can potentially be a useful method for rapidly positioning the catheter tip to the arrhythmic focus during an RCA procedure...
  68. ncbi request reprint An alternative subspace approach to EEG dipole source localization
    Xiao liang Xu
    KC Science and Technologies Inc, Naperville, IL 60565, USA
    Phys Med Biol 49:327-43. 2004
    ..In comparison with RAP-MUSIC, FINES' performance is also better for the cases studied when the noise level is high and/or correlations among dipole sources exist...
  69. ncbi request reprint Spatio-temporal cortical source imaging of brain electrical activity by means of time-varying parametric projection filter
    Junichi Hori
    Department of Biocybernetics, Niigata University, Niigata, 950 2181, Japan
    IEEE Trans Biomed Eng 51:768-77. 2004
    ..The present simulation results indicate that the proposed time-variant tPPF method provides enhanced performance in rejecting time-varying noise, as compared with the time-invariant parametric projection filter...
  70. ncbi request reprint A second-order finite element algorithm for solving the three-dimensional EEG forward problem
    Y C Zhang
    College of Electrical Engineering, Zhejiang University, Hangzhou, People s Republic of China
    Phys Med Biol 49:2975-87. 2004
    ..The effects of dipole eccentricity, size of finite elements and local mesh refinement on solution accuracy are also addressed in the present simulation study...
  71. ncbi request reprint Low resolution brain electromagnetic tomography in a realistic geometry head model: a simulation study
    Lei Ding
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA
    Phys Med Biol 50:45-56. 2005
    ..The present simulation results suggest that the use of the RG head model reduces the localization error of LORETA, and that the RG head model based LORETA is desirable if high localization accuracy is needed...
  72. ncbi request reprint Noninvasive study of neurovascular coupling during graded neuronal suppression
    Nanyin Zhang
    Department of Radiology, Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Cereb Blood Flow Metab 28:280-90. 2008
    ..This study extends the range of the neurovascular coupling relationship from graded neuronal excitation conditions to graded neuronal suppression conditions...
  73. pmc Noninvasive imaging of head-brain conductivity profiles
    Xiaotong Zhang
    College of Electrical Engineering, Zhejiang University, Hangzhou 310027, China
    IEEE Eng Med Biol Mag 27:78-83. 2008
  74. ncbi request reprint Estimation of the effective and functional human cortical connectivity with structural equation modeling and directed transfer function applied to high-resolution EEG
    Laura Astolfi
    Dipartimento di Informatica e Sistemistica, Universita La Sapienza, 00185, Rome, Italy
    Magn Reson Imaging 22:1457-70. 2004
    ..We conclude that the estimation of cortical connectivity can be performed not only with hemodynamic measurements, but also with EEG signals treated with advanced computational techniques...
  75. ncbi request reprint Investigation on magnetoacoustic signal generation with magnetic induction and its application to electrical conductivity reconstruction
    Qingyu Ma
    Department of Biomedical Engineering, University of Minnesota, 312 Church Street SE, Minneapolis, MN 55455, USA
    Phys Med Biol 52:5085-99. 2007
    ....
  76. ncbi request reprint Solving the ECG forward problem by means of a meshless finite element method
    Z S Li
    College of Electrical Engineering, Zhejiang University, Hangzhou, People s Republic of China
    Phys Med Biol 52:N287-96. 2007
    ..The present results suggest that the meshless FEM may provide an alternative for ECG forward solutions...
  77. pmc An enhanced time-frequency-spatial approach for motor imagery classification
    Nobuyuki Yamawaki
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA
    IEEE Trans Neural Syst Rehabil Eng 14:250-4. 2006
    ..The enhanced performance in terms of classification accuracy was found for the proposed approach, with a mean accuracy rate of 91.1% for two subjects studied...
  78. pmc Effects of fMRI-EEG mismatches in cortical current density estimation integrating fMRI and EEG: a simulation study
    Zhongming Liu
    Department of Biomedical Engineering, University of Minnesota, 7 105 BSBE, 312 Church Street, Minneapolis, MN 55455, USA
    Clin Neurophysiol 117:1610-22. 2006
    ....
  79. ncbi request reprint Comparison of different cortical connectivity estimators for high-resolution EEG recordings
    Laura Astolfi
    Dipartimento Informatica e Sistemistica, Universita La Sapienza, Rome, Italy
    Hum Brain Mapp 28:143-57. 2007
    ....
  80. pmc A new magnetic resonance electrical impedance tomography (MREIT) algorithm: the RSM-MREIT algorithm with applications to estimation of human head conductivity
    Nuo Gao
    College of Electrical Engineering, Zhejiang University, People s Republic of China
    Phys Med Biol 51:3067-83. 2006
    ....
  81. pmc Functional cortical source imaging from simultaneously recorded ERP and fMRI
    Chang Hwan Im
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA
    J Neurosci Methods 157:118-23. 2006
    ..The present results demonstrate that reliable cortical source images can be acquired during simultaneous fMRI scanning and they may be used for multimodal functional source imaging studies...
  82. pmc A cortical potential imaging study from simultaneous extra- and intracranial electrical recordings by means of the finite element method
    Yingchun Zhang
    University of Minnesota, Department of Biomedical Engineering, 7 105 Hasselmo Hall, 312 Church Street SE, Minneapolis, MN 55455, USA
    Neuroimage 31:1513-24. 2006
    ..The FEM-based CPI technique provides a means of connecting the simultaneous recorded ECoG and the scalp EEG and promises to become an effective tool to evaluate and validate CPI techniques using clinic data...
  83. ncbi request reprint Estimation of the cortical connectivity by high-resolution EEG and structural equation modeling: simulations and application to finger tapping data
    Laura Astolfi
    Department of Human Physiology and Pharmacology, University of Rome La Sapienza, 00185 Rome, Italy
    IEEE Trans Biomed Eng 52:757-68. 2005
    ..The feasibility of the proposed approach has been shown in a human study using high-resolution EEG recordings related to finger tapping movements...
  84. pmc Magnetoacoustic tomography with magnetic induction (MAT-MI)
    Yuan Xu
    Department of Biomedical Engineering, University of Minnesota, 7 105 BSBE, 312 Church Street, Minneapolis, MN 55455, USA
    Phys Med Biol 50:5175-87. 2005
    ..The promising pilot experimental results suggest the feasibility of the proposed MAT-MI approach...
  85. ncbi request reprint A Monte Carlo and physical phantom evaluation of quantitative In-111 SPECT
    Bin He
    Division of Medical Imaging Physics, The Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N Caroline St JHOC 4250, Baltimore, MD 21287 0859, USA
    Phys Med Biol 50:4169-85. 2005
    ..PVC was important for small structures such as tumours or for organs in close proximity to regions with high activity. The improved quantitative accuracy from QSPECT methods has the potential for improving organ dose estimations in TRT...
  86. ncbi request reprint Noninvasive three-dimensional electrocardiographic imaging of ventricular activation sequence
    Xin Zhang
    Dept of Biomedical Engineering, Univ of Minnesota, 7 105 BSBE, 312 Church St, Minneapolis, MN 55455, USA
    Am J Physiol Heart Circ Physiol 289:H2724-32. 2005
    ..This new 3-D electrocardiographic imaging modality has the potential to guide catheter-based ablative interventions for the treatment of life-threatening cardiac arrhythmias...
  87. pmc On the estimation of the number of dipole sources in EEG source localization
    Xiaoxiao Bai
    Department of Biomedical Engineering University of Minnesota, 7 105 BSBE, 312 Church Street SE, Minneapolis, MN 55455, USA
    Clin Neurophysiol 116:2037-43. 2005
    ..The purpose of the present study was to determine the number of the equivalent dipole sources corresponding to the scalp EEG using the information criterion method based on the instantaneous-state modeling...
  88. ncbi request reprint Classification of motor imagery tasks for brain-computer interface applications by means of two equivalent dipoles analysis
    Baharan Kamousi
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA
    IEEE Trans Neural Syst Rehabil Eng 13:166-71. 2005
    ..In four human subjects, an averaged accuracy of classification of 80% was achieved. The present study suggests the merits and feasibility of applying EEG inverse solutions to BCI applications from noninvasive EEG recordings...
  89. ncbi request reprint Comparison of conventional, model-based quantitative planar, and quantitative SPECT image processing methods for organ activity estimation using In-111 agents
    Bin He
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, MD 21287 0859, USA
    Phys Med Biol 51:3967-81. 2006
    ....
  90. pmc 3D source localization of interictal spikes in epilepsy patients with MRI lesions
    Lei Ding
    Department of Biomedical Engineering, University of Minnesota, 7 105 BSBE, 312 Church Street, Minneapolis, MN 55455, USA
    Phys Med Biol 51:4047-62. 2006
    ..The present study may lead to the establishment of a high-resolution source localization technique from scalp-recorded EEGs for aiding presurgical planning in epilepsy patients...
  91. pmc Integration of EEG/MEG with MRI and fMRI
    Zhongming Liu
    Department of Biomedical Engineering, University of Minnesota, MN 5545, USA
    IEEE Eng Med Biol Mag 25:46-53. 2006
  92. pmc EEG source imaging: correlating source locations and extents with electrocorticography and surgical resections in epilepsy patients
    Lei Ding
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Clin Neurophysiol 24:130-6. 2007
    ..The value of the proposed noninvasive technique for estimating epileptiform activity was supported by satisfactory surgery outcomes...
  93. pmc Evaluation of cortical current density imaging methods using intracranial electrocorticograms and functional MRI
    Xiaoxiao Bai
    University of Minnesota, Department of Biomedical Engineering, 7 105 NHH, 312 Church Street, Minneapolis, MN 55455, USA
    Neuroimage 35:598-608. 2007
    ..The aim of the present study was to evaluate source reconstruction techniques by means of the intracranial electrocorticograms (ECoGs) and functional MRI...
  94. ncbi request reprint Cortical activation mapping of epileptiform activity derived from interictal ECoG spikes
    Yuan Lai
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Epilepsia 48:305-14. 2007
    ..To develop and evaluate a new cortical activation mapping (CAM) method to obtain the neuronal activation sequences from the cortical potential distributions...
  95. ncbi request reprint Imaging electrical impedance from acoustic measurements by means of magnetoacoustic tomography with magnetic induction (MAT-MI)
    Xu Li
    Department of Biomedical Engineering, University of Minnesota, Minneapolis 55455, USA
    IEEE Trans Biomed Eng 54:323-30. 2007
    ..The feasibility of MAT-MI in providing high spatial resolution images containing impedance-related information has also been demonstrated in a phantom experiment...
  96. pmc Ictal source analysis: localization and imaging of causal interactions in humans
    Lei Ding
    Department of Biomedical Engineering, University of Minnesota, 7 105 NHH, 312 Church St SE, Minneapolis, MN 55455, USA
    Neuroimage 34:575-86. 2007
    ..Each step of the ictal source analysis is statistically evaluated in order to guarantee the confidence in the results...
  97. pmc Spatial resolution of EEG cortical source imaging revealed by localization of retinotopic organization in human primary visual cortex
    Chang Hwan Im
    Department of Biomedical Engineering, University of Minnesota, 7 105 Hasselmo Hall, 312 Church St S E, Minneapolis, MN 55455, USA
    J Neurosci Methods 161:142-54. 2007
    ..The present results suggest that the spatial resolution of the EEG cortical source imaging can correctly discriminate cortical activation changes in V1 corresponding to less than 3 degrees visual field changes...
  98. ncbi request reprint Motor imagery classification by means of source analysis for brain-computer interface applications
    Lei Qin
    Department of Biomedical Engineering, The University of Minnesota, 7 105 BSBE, 312 Church Street, Minneapolis, MN 55455, USA
    J Neural Eng 1:135-41. 2004
    ..The present promising results suggest that the source analysis approach could manifest a clearer picture on the cortical activity, and thus facilitate the classification of MI tasks from scalp EEGs...
  99. ncbi request reprint Noninvasive reconstruction of three-dimensional ventricular activation sequence from the inverse solution of distributed equivalent current density
    Zhongming Liu
    Department of Biomedical Engineering, University of Minnesota, Twin Cities, Minneapolis, MN 55455, USA
    IEEE Trans Med Imaging 25:1307-18. 2006
    ....
  100. pmc Estimation of number of independent brain electric sources from the scalp EEGs
    Xiaoxiao Bai
    Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA
    IEEE Trans Biomed Eng 53:1883-92. 2006
    ..The present study suggests that the information criterion method may provide a useful means in estimating the number of independent brain electrical sources from EEG/MEG measurements...
  101. ncbi request reprint Three-dimensional myocardial activation imaging in a rabbit model
    Chenguang Liu
    University of Minnesota, Minneapolis 55455, USA
    IEEE Trans Biomed Eng 53:1813-20. 2006
    ..20 and the localization error was 5.1 mm. The present simulation and experimental results suggest the merits of the 3DECI imaging approach, and the validity of intracardiac mapping as a tool to evaluate the 3DECI...