Samir M Hanash

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint Early changes in gene expression profiles of hepatic GVHD uncovered by oligonucleotide microarrays
    Tamotsu Ichiba
    Department of Internal Medicine, University of Michigan Cancer Center, Ann Arbor, USA
    Blood 102:763-71. 2003
  2. ncbi request reprint Operomics: integrated genomic and proteomic profiling of cells and tissues
    Samir M Hanash
    University of Michigan, Department of Pediatrics, Ann Arbor, USA
    Brief Funct Genomic Proteomic 1:10-22. 2002
  3. ncbi request reprint Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas
    Charles T Miller
    Department of Surgery, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Oncogene 22:7950-7. 2003
  4. ncbi request reprint Overexpression of oncoprotein 18 correlates with poor differentiation in lung adenocarcinomas
    Guoan Chen
    Department of Surgery, The University of Michigan, Ann Arbor, Michigan 48109, USA
    Mol Cell Proteomics 2:107-16. 2003
  5. ncbi request reprint Reduced selenium-binding protein 1 expression is associated with poor outcome in lung adenocarcinomas
    Guoan Chen
    Department of Surgery, The University of Michigan, Ann Arbor, Michigan 48109, USA
    J Pathol 202:321-9. 2004
  6. ncbi request reprint Proteomic analysis of eIF-5A in lung adenocarcinomas
    Guoan Chen
    Department of Surgery, The University of Michigan, Ann Arbor, MI 48109 086, USA
    Proteomics 3:496-504. 2003
  7. ncbi request reprint An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer
    Su Hyung Hong
    Department of Pediatrics, University of Michigan Medical School, 1150 West Medical Center Drive, Ann Arbor, MI 48109 0656, USA
    Cancer Res 64:5504-10. 2004
  8. pmc Protein profiles associated with survival in lung adenocarcinoma
    Guoan Chen
    Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA
    Proc Natl Acad Sci U S A 100:13537-42. 2003
  9. ncbi request reprint Novel candidate targets of beta-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adenocarcinomas
    Donald R Schwartz
    Department of Pathology, College of Literature Science and the Arts, University of Michigan, Ann Arbor, Michigan 48109 0638, USA
    Cancer Res 63:2913-22. 2003
  10. ncbi request reprint Genomic and proteomic analyses of vascular endothelial growth factor and insulin-like growth factor-binding protein 3 in lung adenocarcinomas
    Tarek G Gharib
    Department of Surgery, University of Michigan, Ann Arbor 48109, USA
    Clin Lung Cancer 5:307-12. 2004

Collaborators

Detail Information

Publications58

  1. ncbi request reprint Early changes in gene expression profiles of hepatic GVHD uncovered by oligonucleotide microarrays
    Tamotsu Ichiba
    Department of Internal Medicine, University of Michigan Cancer Center, Ann Arbor, USA
    Blood 102:763-71. 2003
    ....
  2. ncbi request reprint Operomics: integrated genomic and proteomic profiling of cells and tissues
    Samir M Hanash
    University of Michigan, Department of Pediatrics, Ann Arbor, USA
    Brief Funct Genomic Proteomic 1:10-22. 2002
    ..In this paper, the approaches for genomic and proteomic profiling and the contribution of translational control are reviewed...
  3. ncbi request reprint Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas
    Charles T Miller
    Department of Surgery, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Oncogene 22:7950-7. 2003
    ..05). This study provides the first quantitative analysis of discrete CRKI and CRKII protein isoforms in human lung tumors and provides evidence that the C-CRK proto-oncogene may foment a more aggressive phenotype in lung cancers...
  4. ncbi request reprint Overexpression of oncoprotein 18 correlates with poor differentiation in lung adenocarcinomas
    Guoan Chen
    Department of Surgery, The University of Michigan, Ann Arbor, Michigan 48109, USA
    Mol Cell Proteomics 2:107-16. 2003
    ....
  5. ncbi request reprint Reduced selenium-binding protein 1 expression is associated with poor outcome in lung adenocarcinomas
    Guoan Chen
    Department of Surgery, The University of Michigan, Ann Arbor, Michigan 48109, USA
    J Pathol 202:321-9. 2004
    ..Analysis of the tumour proliferation status using Ki-67 suggests that down-regulated expression of SBP1 may reflect increased cell proliferation and decreased differentiation in lung adenocarcinomas...
  6. ncbi request reprint Proteomic analysis of eIF-5A in lung adenocarcinomas
    Guoan Chen
    Department of Surgery, The University of Michigan, Ann Arbor, MI 48109 086, USA
    Proteomics 3:496-504. 2003
    ..Moreover, the investigation on agents that inhibit eIF-5A function is encouraged...
  7. ncbi request reprint An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer
    Su Hyung Hong
    Department of Pediatrics, University of Michigan Medical School, 1150 West Medical Center Drive, Ann Arbor, MI 48109 0656, USA
    Cancer Res 64:5504-10. 2004
    ..The detection of autoantibodies to calreticulin isoforms may have utility for the early diagnosis of pancreatic cancer...
  8. pmc Protein profiles associated with survival in lung adenocarcinoma
    Guoan Chen
    Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA
    Proc Natl Acad Sci U S A 100:13537-42. 2003
    ..These studies identify new prognostic biomarkers and indicate that protein expression profiles can predict the outcome of patients with early-stage lung cancer...
  9. ncbi request reprint Novel candidate targets of beta-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adenocarcinomas
    Donald R Schwartz
    Department of Pathology, College of Literature Science and the Arts, University of Michigan, Ann Arbor, Michigan 48109 0638, USA
    Cancer Res 63:2913-22. 2003
    ....
  10. ncbi request reprint Genomic and proteomic analyses of vascular endothelial growth factor and insulin-like growth factor-binding protein 3 in lung adenocarcinomas
    Tarek G Gharib
    Department of Surgery, University of Michigan, Ann Arbor 48109, USA
    Clin Lung Cancer 5:307-12. 2004
    ..Among other highly correlated genes, several, including bradykinin receptor B2, suggest additional cellular processes that were not previously known to be associated with VEGF expression in lung adenocarcinoma...
  11. ncbi request reprint Discovery of cancer biomarkers through the use of mouse models
    Rork Kuick
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor, MI, USA
    Cancer Lett 249:40-8. 2007
    ..Proteomic studies of mouse models of cancer allow assessment of the range of changes in plasma proteins that occur with tumor development and may lead to the identification of potential cancer markers applicable to humans...
  12. pmc Distinctive serum protein profiles involving abundant proteins in lung cancer patients based upon antibody microarray analysis
    Wei Min Gao
    Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA
    BMC Cancer 5:110. 2005
    ..We hypothesized that distinctive profiles may result from the differential expression of relatively abundant serum proteins associated with the host response...
  13. ncbi request reprint A wide range of protein isoforms in serum and plasma uncovered by a quantitative intact protein analysis system
    David E Misek
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor, MI, USA
    Proteomics 5:3343-52. 2005
    ..IPAS provides a high resolution, high sensitivity, and quantitative approach for the analysis of serum and plasma proteins, and allows assessment of PTMs as a potential source of biomarkers...
  14. pmc Identification of novel alternative splice isoforms of circulating proteins in a mouse model of human pancreatic cancer
    Rajasree Menon
    Center for Computational Medicine and Biology and Pediatric Endocrinology, University of Michigan, 100 Washtenaw Avenue, Palmer Commons, Ann Arbor, MI 48109, USA
    Cancer Res 69:300-9. 2009
    ..Our results show that, in a mouse model for human pancreatic cancer, novel and differentially expressed alternative splice isoforms are detectable in plasma and may be a source of candidate biomarkers...
  15. ncbi request reprint Analysis of tumor-host interactions by gene expression profiling of lung adenocarcinoma xenografts identifies genes involved in tumor formation
    Chad J Creighton
    Bioinformatics Program, Department of Pathology, University of Michigan, 4237 Med Sci I, 1150 West Medical Center Drive, Ann Arbor, MI 48109, USA
    Mol Cancer Res 3:119-29. 2005
    ..Thus, analysis of tumor xenografts by gene expression profiling has the potential for identifying genes involved in tumor development that may not be expressed in cancer cells grown in vitro...
  16. pmc Mxi1-0, an alternatively transcribed Mxi1 isoform, is overexpressed in glioblastomas
    Lars D Engstrom
    Section of Pediatric Hematology Oncology, Department of Pediatrics and Communicable Diseases, The University of Michigan School of Medicine, Ann Arbor, MI 48109 0936, USA
    Neoplasia 6:660-73. 2004
    ..The identification of Mxi1-0 as an alternatively transcribed Mxi1 isoform has significant implications for the interpretation of previous Mxi1 studies, particularly those related to the phenotype of the mxi1 knockout mouse...
  17. ncbi request reprint The hepatocyte nuclear factor 3 alpha gene, HNF3alpha (FOXA1), on chromosome band 14q13 is amplified and overexpressed in esophageal and lung adenocarcinomas
    Lin Lin
    Section of General Thoracic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Cancer Res 62:5273-9. 2002
    ..Amplification of HNF3alpha in esophageal and lung tumors may suggest a potential oncogenic role for this gene in tumorigenesis...
  18. ncbi request reprint Challenges in deriving high-confidence protein identifications from data gathered by a HUPO plasma proteome collaborative study
    David J States
    University of Michigan, 100 Washtenaw Rd, Palmer Commons 2035B, Ann Arbor, Michigan 48109, USA
    Nat Biotechnol 24:333-8. 2006
    ....
  19. ncbi request reprint Molecular profiling of the immune response in colon cancer using protein microarrays: occurrence of autoantibodies to ubiquitin C-terminal hydrolase L3
    Myeong J Nam
    Department of Pediatrics, University of Michigan Medical School, 1150 W Medical Drive, Ann Arbor, MI 48109 0656, USA
    Proteomics 3:2108-15. 2003
    ..Our findings indicate the occurrence of an immune response to a broad set of antigens in colon cancer and the feasibility of identifying the antigenic targets using a combination of protein microarrays and mass spectrometry...
  20. pmc Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway
    Eduardo Vilar
    Department of Internal Medicine, The University of Michigan Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Clin Cancer Res 15:2829-39. 2009
    ..Our objective was to identify low molecular weight compounds with preferential activity against MSI colorectal cancers using combined gene expression data sets...
  21. ncbi request reprint Oligonucleotide-directed microarray gene profiling of pancreatic adenocarcinoma
    David E Misek
    Department of Pediatric Oncology, University of Michigan, Ann Arbor, USA
    Methods Mol Med 103:175-87. 2005
    ..The details of the approach we utilized are reported here, including information on experimental design, sample collection, expression level measurements, and data analysis for gene profiling...
  22. ncbi request reprint Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function
    Bong Kyung Shin
    Departments of Pediatrics and Pathology, University of Michigan, Ann Arbor, Michigan 48109 0656, USA
    J Biol Chem 278:7607-16. 2003
    ..Comprehensive profiling of the cell surface proteome provides an effective approach for the identification of commonly occurring proteins as well as proteins with restricted expression patterns in this compartment...
  23. ncbi request reprint Transforming properties of a Q18-->E mutation of the microtubule regulator Op18
    David E Misek
    Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA
    Cancer Cell 2:217-28. 2002
    ..These results suggest that the somatic mutation identified in Op18 has profound effects on cell homeostasis that may lead to tumorigenicity...
  24. ncbi request reprint Intact-protein-based high-resolution three-dimensional quantitative analysis system for proteome profiling of biological fluids
    Hong Wang
    Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109, USA
    Mol Cell Proteomics 4:618-25. 2005
    ..IPAS provides a combination of comprehensive profiling and quantitative analysis, with a substantial dynamic range, for disease-related applications...
  25. ncbi request reprint Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas
    Donald R Schwartz
    Departments of Pathology, The University of Michigan, Ann Arbor, Michigan 48109, USA
    Cancer Res 62:4722-9. 2002
    ..Moreover, these studies provide a foundation for the development of new type-specific diagnostic strategies and treatments for ovarian cancer...
  26. pmc A biomarker panel for acute graft-versus-host disease
    Sophie Paczesny
    Department of Pediatrics, University of Michigan, Ann Arbor, USA
    Blood 113:273-8. 2009
    ..A panel of 4 biomarkers can confirm the diagnosis of GVHD in patients at onset of clinical symptoms of GVHD and provide prognostic information independent of GVHD severity...
  27. ncbi request reprint Application of proteomic technologies to tumor analysis
    David E Misek
    Department of Pediatrics, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, Michigan, 48109 0656, USA
    Pharmacogenomics 5:1129-37. 2004
    ....
  28. ncbi request reprint Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database
    Gilbert S Omenn
    Internal Medicine, University of Michigan, Ann Arbor, MI 48109 0656, USA
    Proteomics 5:3226-45. 2005
    ....
  29. pmc Distinct transcriptional profiles of adrenocortical tumors uncovered by DNA microarray analysis
    Thomas J Giordano
    Departments of Pathology, Pediatrics, Surgery, and Biostatistics, University of Michigan Health System, Ann Arbor, Michigan 48109 0054, USA
    Am J Pathol 162:521-31. 2003
    ..Moreover, we identified several genes that represent potential diagnostic markers and may play a role in the pathogenesis of ACC...
  30. pmc Microarray analyses during adipogenesis: understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism
    Sarah E Ross
    Department of Physiology, University of Michigan School of Medicine, Ann Arbor, Michigan 48109, USA
    Mol Cell Biol 22:5989-99. 2002
    ..These findings demonstrate new metabolic roles for LXR alpha and increase our understanding of adipogenesis...
  31. ncbi request reprint Discordant protein and mRNA expression in lung adenocarcinomas
    Guoan Chen
    Department of Surgery, University of Michigan, Ann Arbor, Michigan 48109, USA
    Mol Cell Proteomics 1:304-13. 2002
    ..Using a quantitative analysis of mRNA and protein expression within the same lung adenocarcinomas, we showed that only a subset of the proteins exhibited a significant correlation with mRNA abundance...
  32. pmc N-myc modulates expression of p73 in neuroblastoma
    Xiaoxiang Zhu
    Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Neoplasia 4:432-9. 2002
    ..Our data suggest that the N-myc gene modulates expression of p73, allowing neuroblastoma cells to escape the growth suppressing properties of p73...
  33. ncbi request reprint Proteomic analysis of lung adenocarcinoma: identification of a highly expressed set of proteins in tumors
    Guoan Chen
    Section of General Thoracic Surgery, Departments of Surgery, University of Michigan, Ann Arbor, Michigan 48109, USA
    Clin Cancer Res 8:2298-305. 2002
    ..The goal of this study was to identify potential protein markers in lung adenocarcinomas...
  34. ncbi request reprint A distinct repertoire of autoantibodies in hepatocellular carcinoma identified by proteomic analysis
    Francois Le Naour
    Departments of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan 48109 0666, USA
    Mol Cell Proteomics 1:197-203. 2002
    ..We conclude that a distinct repertoire of autoantibodies is associated with HCC that may have utility in early diagnosis of HCC among high risk subjects with chronic hepatitis...
  35. ncbi request reprint Integrating cancer genomics and proteomics in the post-genome era
    Samir M Hanash
    University of Michigan Medical Center, Ann Arbor, MI 48109 0656, USA
    Proteomics 2:69-75. 2002
    ..Our current approach is illustrated with findings stemming from our studies of human gliomas...
  36. ncbi request reprint Food deprivation-induced expression of minoxidil sulfotransferase in the hypothalamus uncovered by microarray analysis
    Ji Yao Li
    Department of Surgery, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Biol Chem 277:9069-76. 2002
    ..This study identifies a novel gene induced by fasting and demonstrates the feasibility of using oligonucleotide microarrays for the study of complex neuronal processes...
  37. doi request reprint Human Proteinpedia enables sharing of human protein data
    Suresh Mathivanan
    Nat Biotechnol 26:164-7. 2008
  38. doi request reprint Plasma proteome profiling of a mouse model of breast cancer identifies a set of up-regulated proteins in common with human breast cancer cells
    Sharon J Pitteri
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    J Proteome Res 7:1481-9. 2008
    ....
  39. doi request reprint Mining the plasma proteome for cancer biomarkers
    Samir M Hanash
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, Washington 98109, USA
    Nature 452:571-9. 2008
    ..Achieving these objectives requires high-quality specimens with well-matched controls, reagent resources, and an efficient process to confirm discoveries through independent validation studies...
  40. doi request reprint Isoform analysis of LC-MS/MS data from multidimensional fractionation of the serum proteome
    Alexei L Krasnoselsky
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    J Proteome Res 7:2546-52. 2008
    ..Potential applications include identification of differentially expressed isoforms in disease states...
  41. doi request reprint Increased throughput and reduced carryover of mass spectrometry-based proteomics using a high-efficiency nonsplit nanoflow parallel dual-column capillary HPLC system
    Hong Wang
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    J Proteome Res 7:2743-55. 2008
    ....
  42. pmc Occurrence of autoantibodies to annexin I, 14-3-3 theta and LAMR1 in prediagnostic lung cancer sera
    Ji Qiu
    Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    J Clin Oncol 26:5060-6. 2008
    ....
  43. ncbi request reprint Identification of tumor-associated antigens using proteomics
    François L Naour
    INSERM U268, Hospital Paul Brousse, 94807 Villejuif Cedex, France
    Technol Cancer Res Treat 1:257-62. 2002
    ..On the other hand, the analysis of the expression levels of some of the antigenic proteins has revealed differential expression in tumors as compared with healthy tissues that might explain antigenicity...
  44. pmc A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions
    Chad J Creighton
    The Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA
    RNA 14:2290-6. 2008
    ..The software and Excel VBA source code are freely available at http://sigterms.sourceforge.net...
  45. ncbi request reprint Identification of defensin alpha6 as a potential biomarker in colon adenocarcinoma
    Myeong J Nam
    National Institute of Health, Seoul 122 701, Korea
    J Biol Chem 280:8260-5. 2005
    ..4% (95% CI 54.6-81.8), specificity of 83.3% (58.6-96.4), and positive predictive value of 91.9% (78.1-98.3). These findings justify a prospective assessment of serum defensin alpha6 protein as a screening tool for colon cancer...
  46. ncbi request reprint A functional annotation of subproteomes in human plasma
    Peipei Ping
    Department of Physiology and Medicine, Division of Cardiology, Cardiovascular Research Laboratories, University of California, Los Angeles, CA, USA
    Proteomics 5:3506-19. 2005
    ..The HPPP-organized, multi-laboratory effort, as described herein, resulted in much synergy and was essential to the success of this project...
  47. pmc Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction
    Jörg van den Boom
    Department of Neuropathology, Heinrich Heine University, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    Am J Pathol 163:1033-43. 2003
    ..Thus, we identified and validated a set of interesting candidate genes whose differential expression likely plays a role in astrocytoma progression...
  48. ncbi request reprint The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis
    Jose M Cuezva
    Departamento de Biologia Molecular, Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma de Madrid, E 28049 Madrid, Spain
    Carcinogenesis 25:1157-63. 2004
    ..We conclude that the bioenergetic signature of lung adenocarcinomas is altered, further providing a relevant marker for the diagnosis and classification of lung adenocarcinomas, and for the prognosis of lung cancer patients...
  49. ncbi request reprint Identification of 14-3-3 theta as an antigen that induces a humoral response in lung cancer
    Sandra R Pereira-Faca
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer Res 67:12000-6. 2007
    ..5 proteins previously identified as associated with autoantibodies in lung cancer, gave a sensitivity of 55% at 95% specificity (area under the curve, 0.838) in discriminating lung cancer at the preclinical stage from matched controls...
  50. pmc Proteomic analysis of ovarian cancer cells reveals dynamic processes of protein secretion and shedding of extra-cellular domains
    Vitor M Faca
    Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
    PLoS ONE 3:e2425. 2008
    ..We have characterized the cell surface proteome and the proteins released into the extra-cellular milieu of three ovarian cancer cell lines, CaOV3, OVCAR3 and ES2 and of ovarian tumor cells enriched from ascites fluid...
  51. pmc A mouse to human search for plasma proteome changes associated with pancreatic tumor development
    Vitor M Faca
    Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
    PLoS Med 5:e123. 2008
    ....
  52. pmc ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation
    Melanie Ehrlich
    Hayward Human Genetics Program, Tulane Medical School, New Orleans, LA 70112, USA
    Autoimmunity 41:253-71. 2008
    ....
  53. ncbi request reprint Methods of comparative proteomic profiling for disease diagnostics
    Laura F Steel
    Department of Microbiology and Immunology, Drexel University College of Medicine, Doylestown, PA 18901, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 815:275-84. 2005
    ....
  54. ncbi request reprint Proteomic approaches for cancer biomarker discovery in plasma
    Sharon J Pitteri
    Expert Rev Proteomics 4:589-90. 2007
  55. ncbi request reprint Modification of host lipid raft proteome upon hepatitis C virus replication
    Petra Mannová
    Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Mol Cell Proteomics 5:2319-25. 2006
    ..Our findings indicate that protein subcellular relocalization occurs in HCV-containing cells that can directly affect HCV replication...
  56. ncbi request reprint Cellular retinoic acid-binding protein II is a direct transcriptional target of MycN in neuroblastoma
    Anu Gupta
    Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA
    Cancer Res 66:8100-8. 2006
    ..Our findings also suggest that CRABP-II may be a potential therapeutic target for neuroblastoma...
  57. ncbi request reprint Long-term ethanol consumption alters pancreatic gene expression in rats: a possible connection to pancreatic injury
    Constanze H Kubisch
    Department of Cancer Biology, MD Anderson Cancer Center, University of Texas, Houston, TX 77230 1429, USA
    Pancreas 33:68-76. 2006
    ..The mechanisms responsible for this sensitization are unknown. To determine whether alterations in pancreatic gene expression might participate in ethanol-mediated sensitization, we performed gene-profiling analysis...
  58. pmc A mouse plasma peptide atlas as a resource for disease proteomics
    Qing Zhang
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Genome Biol 9:R93. 2008
    ..A major finding from this study is the identification of novel isoforms and transcript variants not previously predicted from genome analysis...