Jennifer H Han

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. doi request reprint Epidemiology of Carbapenem-Resistant Klebsiella pneumoniae in a Network of Long-Term Acute Care Hospitals
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine
    Clin Infect Dis . 2016
  2. pmc Epidemiology and characteristics of Escherichia coli sequence type 131 (ST131) from long-term care facility residents colonized intestinally with fluoroquinolone-resistant Escherichia coli
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, PA Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA Electronic address
    Diagn Microbiol Infect Dis . 2016
  3. pmc Comparative Effectiveness of Diabetic Oral Medications Among HIV-Infected and HIV-Uninfected Veterans
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
    Diabetes Care 40:218-225. 2017
  4. pmc Use of a Combination Biomarker Algorithm To Identify Medical Intensive Care Unit Patients with Suspected Sepsis at Very Low Likelihood of Bacterial Infection
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Antimicrob Agents Chemother 59:6494-500. 2015
  5. pmc Clinical and molecular epidemiology of Escherichia coli sequence type 131 among hospitalized patients colonized intestinally with fluoroquinolone-resistant E. coli
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Antimicrob Agents Chemother 58:7003-6. 2014
  6. pmc Temporal changes in resistance mechanisms in colonizing Escherichia coli isolates with reduced susceptibility to fluoroquinolones
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Diagn Microbiol Infect Dis 76:491-6. 2013
  7. pmc Risk factors for gastrointestinal tract colonization with extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella species in hospitalized patients
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Infect Control Hosp Epidemiol 33:1242-5. 2012
  8. pmc Risk factors for infection or colonization with CTX-M extended-spectrum-β-lactamase-positive Escherichia coli
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Antimicrob Agents Chemother 56:5575-80. 2012
  9. pmc Risk factors for efflux pump overexpression in fluoroquinolone-resistant Escherichia coli
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Infect Dis 206:1597-603. 2012
  10. pmc Derivation and validation of clinical prediction rules for reduced vancomycin susceptibility in Staphylococcus aureus bacteraemia
    J H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Epidemiol Infect 141:165-73. 2013

Collaborators

Detail Information

Publications25

  1. doi request reprint Epidemiology of Carbapenem-Resistant Klebsiella pneumoniae in a Network of Long-Term Acute Care Hospitals
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine
    Clin Infect Dis . 2016
    ..The objective of this study was to describe the epidemiologic characteristics of CRKP in a network of United States LTACHs...
  2. pmc Epidemiology and characteristics of Escherichia coli sequence type 131 (ST131) from long-term care facility residents colonized intestinally with fluoroquinolone-resistant Escherichia coli
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, PA Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA Electronic address
    Diagn Microbiol Infect Dis . 2016
    ..Future studies should determine the risk factors for infection among ST131-colonized residents, and assess the potential for increased transmissibility of ST131 in the long-term care setting...
  3. pmc Comparative Effectiveness of Diabetic Oral Medications Among HIV-Infected and HIV-Uninfected Veterans
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
    Diabetes Care 40:218-225. 2017
    ..Type 2 diabetes is increasingly common in HIV-infected individuals. The objective of this study was to compare the glycemic effectiveness of oral diabetic medications among patients with and without HIV infection...
  4. pmc Use of a Combination Biomarker Algorithm To Identify Medical Intensive Care Unit Patients with Suspected Sepsis at Very Low Likelihood of Bacterial Infection
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Antimicrob Agents Chemother 59:6494-500. 2015
    ..Future studies should focus on the use of these algorithms to improve antibiotic use in the ICU setting. ..
  5. pmc Clinical and molecular epidemiology of Escherichia coli sequence type 131 among hospitalized patients colonized intestinally with fluoroquinolone-resistant E. coli
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Antimicrob Agents Chemother 58:7003-6. 2014
    ..003). Furthermore, all 19 clonally related isolates were ST131. Future studies should identify potential transmissibility differences between ST131 and non-ST131 strains. ..
  6. pmc Temporal changes in resistance mechanisms in colonizing Escherichia coli isolates with reduced susceptibility to fluoroquinolones
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Diagn Microbiol Infect Dis 76:491-6. 2013
    ..0 mean days, respectively; P = 0.01) prior to sampling. Our data demonstrate the significant variability of resistance mechanisms in colonizing E. coli isolates among hospitalized patients. ..
  7. pmc Risk factors for gastrointestinal tract colonization with extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella species in hospitalized patients
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Infect Control Hosp Epidemiol 33:1242-5. 2012
    ..The prevalence of colonization with ESBL-EK was 2.6%. Colonization was associated with cirrhosis, longer duration of hospital stay prior to surveillance, and prior exposure to clindamycin or meropenem...
  8. pmc Risk factors for infection or colonization with CTX-M extended-spectrum-β-lactamase-positive Escherichia coli
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Antimicrob Agents Chemother 56:5575-80. 2012
    ..coli. Future studies will need to focus on outcomes associated with infections due to CTX-M-positive E. coli, as well as infection control strategies to limit the spread of these increasingly common organisms...
  9. pmc Risk factors for efflux pump overexpression in fluoroquinolone-resistant Escherichia coli
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Infect Dis 206:1597-603. 2012
    ....
  10. pmc Derivation and validation of clinical prediction rules for reduced vancomycin susceptibility in Staphylococcus aureus bacteraemia
    J H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Epidemiol Infect 141:165-73. 2013
    ..The availability of an easy and rapid clinical prediction rule for early identification of RVS can be used to help guide the timely and individualized management of these serious infections...
  11. pmc The effect of staphylococcal cassette chromosome mec (SCCmec) type on clinical outcomes in methicillin-resistant Staphylococcus aureus bacteremia
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, 19104, USA
    J Infect 66:41-7. 2013
    ..The objective of this study was to determine the association between SCCmec type and mortality in MRSA bacteremia...
  12. pmc HIV infection and glycemic response to newly initiated diabetic medical therapy
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, 3rd Floor, Silverstein Building, Ste E, Philadelphia, PA 19104, USA
    AIDS 26:2087-95. 2012
    ..The objective of this study was to compare the effectiveness of initial diabetic medical therapy in patients with and without HIV infection...
  13. pmc Reduced vancomycin susceptibility and staphylococcal cassette chromosome mec (SCCmec) type distribution in methicillin-resistant Staphylococcus aureus bacteraemia
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Antimicrob Chemother 67:2346-9. 2012
    ..The objective of this study was to examine the association between reduced vancomycin susceptibility (RVS) and staphylococcal cassette chromosome mec (SCCmec) type in MRSA bloodstream isolates...
  14. pmc Effect of reduced vancomycin susceptibility on clinical and economic outcomes in Staphylococcus aureus bacteremia
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Antimicrob Agents Chemother 56:5164-70. 2012
    ..aureus but not methicillin-resistant S. aureus. Further research is needed to identify optimal treatment strategies to reduce mortality associated with RVS in S. aureus bacteremia...
  15. doi request reprint Relapsing Legionella pneumophila cellulitis: a case report and review of the literature
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, 3400 Spruce St, 3 Silverstein, Ste E, Philadelphia, PA 19104, USA
    J Infect Chemother 16:439-42. 2010
    ..should be considered in the etiology of cellulitis, particularly in the setting of immunocompromise, in cases that are refractory to conventional antibiotics routinely administered for skin and soft tissue infections...
  16. pmc Impact of antibiotic use during hospitalization on the development of gastrointestinal colonization with Escherichia coli with reduced fluoroquinolone susceptibility
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
    Infect Control Hosp Epidemiol 34:1070-6. 2013
    ..The objective of this study was to identify risk factors for the development of FQREC gastrointestinal tract colonization in hospitalized patients, including the impact of antibiotics prescribed during hospitalization...
  17. pmc The effect of a hospital-wide urine culture screening intervention on the incidence of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella species
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    Infect Control Hosp Epidemiol 34:1160-6. 2013
    ..The objective of this study was to evaluate the impact of a urine culture screening strategy on the incidence of ESBL-EK...
  18. pmc Risk factors for the development of gastrointestinal colonization with fluoroquinolone-resistant Escherichia coli in residents of long-term care facilities
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine
    J Infect Dis 209:420-5. 2014
    ..The objective of this study was to assess risk factors for the development of fluoroquinolone (FQ)-resistant Escherichia coli gastrointestinal tract colonization in long-term care facility (LTCF) residents...
  19. pmc Combined biomarkers discriminate a low likelihood of bacterial infection among surgical intensive care unit patients with suspected sepsis
    Brendan J Kelly
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA Electronic address
    Diagn Microbiol Infect Dis 85:109-15. 2016
    ..The combination of A2M and PCT discriminated bacterial sepsis from other SIRS among SICU patients with suspected sepsis...
  20. pmc Defining relatedness in studies of transmission of antimicrobial-resistant organisms: variability in definitions across studies and impact of different approaches on study conclusions
    Rachel M Greenblatt
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Infect Control Hosp Epidemiol 34:40-8. 2013
    ..We used fluoroquinolone-resistant Escherichia coli (FQREC) as a model to characterize variability in definitions of relatedness across studies and to evaluate the resultant impact on study conclusions...
  21. ncbi request reprint Clinical and Molecular Characterization of Community-Onset Urinary Tract Infections Due to Extended-Spectrum Cephalosporin-Resistant Enterobacteriaceae
    Judith A Anesi
    1Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
    Infect Control Hosp Epidemiol 37:1433-1439. 2016
    ..There was a high prevalence of CTX-M among our community isolates. Further studies are needed to determine strategies to limit emergence of these organisms in the community. Infect Control Hosp Epidemiol 2016;1433-1439...
  22. pmc The Epidemiology of Carbapenem-Resistant Klebsiella pneumoniae Colonization and Infection among Long-Term Acute Care Hospital Residents
    John P Mills
    1Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    Infect Control Hosp Epidemiol 37:55-60. 2016
    ..Infect. Control Hosp. Epidemiol. 2015;37(1):55-60. ..
  23. pmc Risk factors for infection with Escherichia coli in nursing home residents colonized with fluoroquinolone-resistant E. coli
    Sara Manning
    1Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
    Infect Control Hosp Epidemiol 36:575-7. 2015
    ..coli. Among 94 subjects, 11 (12%) developed infections with E. coli. Risk factors included the presence of a urinary catheter or tracheostomy, diabetes mellitus, and trimethoprim-sulfamethoxazole exposure...
  24. pmc Point-of-prescription interventions to improve antimicrobial stewardship
    Keith W Hamilton
    Division of Infectious Diseases, Hospital of the University of Pennsylvania, Philadelphia
    Clin Infect Dis 60:1252-8. 2015
    ..This review discusses interventions focusing on antimicrobial prescribing at the point of prescription as well as a pilot project to engage unit-based healthcare providers in antimicrobial stewardship. ..
  25. pmc Environmental transmission of Clostridium difficile: association between hospital room size and C. difficile Infection
    Justine Jou
    1Center for Public Health Initiatives, University of Pennsylvania, Philadelphia, Pennsylvania
    Infect Control Hosp Epidemiol 36:564-8. 2015
    ..To evaluate the association between hospital room square footage and acquisition of nosocomial Clostridium difficile infection (CDI)...