TEAL HALLSTRAND

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Relationship between levels of secreted phospholipase A₂ groups IIA and X in the airways and asthma severity
    T S Hallstrand
    Department of Medicine, Divisions of Pulmonary and Critical Care, University of Washington, Seattle, WA 98195, USA
    Clin Exp Allergy 41:801-10. 2011
  2. pmc Regulation and function of epithelial secreted phospholipase A2 group X in asthma
    Teal S Hallstrand
    Department of Medicine, University ofWashington, Seattle, WA, USA
    Am J Respir Crit Care Med 188:42-50. 2013
  3. pmc Epithelial regulation of eicosanoid production in asthma
    Teal S Hallstrand
    Division of Pulmonary and Critical Care, University of Washington, Box 356522, 1959 NE Pacific Street, Seattle, WA 98195, USA
    Pulm Pharmacol Ther 25:432-7. 2012
  4. pmc Role of MUC5AC in the pathogenesis of exercise-induced bronchoconstriction
    Teal S Hallstrand
    Department of Medicine, University of Washington, Seattle WA 98195 6522, USA
    J Allergy Clin Immunol 119:1092-8. 2007
  5. ncbi request reprint Aerobic conditioning in mild asthma decreases the hyperpnea of exercise and improves exercise and ventilatory capacity
    T S Hallstrand
    Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA 98195 8673, USA
    Chest 118:1460-9. 2000
  6. pmc Secreted phospholipase A2 group X overexpression in asthma and bronchial hyperresponsiveness
    Teal S Hallstrand
    Division of Pulmonary and Critical Care, Department of Medicine, University of Washington, Box 356522, Seattle, WA 98195, USA
    Am J Respir Crit Care Med 176:1072-8. 2007
  7. ncbi request reprint Role of leukotrienes in exercise-induced bronchoconstriction
    Teal S Hallstrand
    Division of Pulmonary and Critical Care, University of Washington, Seattle, WA 98195, USA
    Curr Allergy Asthma Rep 9:18-25. 2009
  8. doi request reprint Initial test of the seattle asthma severity and control questionnaire: a multidimensional assessment of asthma severity and control
    Teal S Hallstrand
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    Ann Allergy Asthma Immunol 103:225-32. 2009
  9. pmc Transglutaminase 2, a novel regulator of eicosanoid production in asthma revealed by genome-wide expression profiling of distinct asthma phenotypes
    Teal S Hallstrand
    Division of Pulmonary and Critical Care, Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 5:e8583. 2010
  10. pmc Genetic pleiotropy between asthma and obesity in a community-based sample of twins
    Teal S Hallstrand
    Department of Medicine, University of Washington, Seattle, 98195, USA
    J Allergy Clin Immunol 116:1235-41. 2005

Research Grants

  1. Secretory Phospholipase A2s in Airway Pathophysiology
    Teal S Hallstrand; Fiscal Year: 2010

Detail Information

Publications27

  1. pmc Relationship between levels of secreted phospholipase A₂ groups IIA and X in the airways and asthma severity
    T S Hallstrand
    Department of Medicine, Divisions of Pulmonary and Critical Care, University of Washington, Seattle, WA 98195, USA
    Clin Exp Allergy 41:801-10. 2011
    ..Conclusions and Clinical Relevance These data indicate that sPLA(2) -IIA and sPLA(2) -X are the major sPLA(2) s in human airways, and suggest a link between the levels of sPLA(2) -X in the airways and several features of asthma...
  2. pmc Regulation and function of epithelial secreted phospholipase A2 group X in asthma
    Teal S Hallstrand
    Department of Medicine, University ofWashington, Seattle, WA, USA
    Am J Respir Crit Care Med 188:42-50. 2013
    ..Secreted phospholipase A2 group X (sPLA2-X) plays a key role in regulating eicosanoid formation and the development of inflammation and AHR in murine models...
  3. pmc Epithelial regulation of eicosanoid production in asthma
    Teal S Hallstrand
    Division of Pulmonary and Critical Care, University of Washington, Box 356522, 1959 NE Pacific Street, Seattle, WA 98195, USA
    Pulm Pharmacol Ther 25:432-7. 2012
    ..Collectively, these studies identify a novel mechanism linking the airway epithelium to the production of inflammatory eicosanoids by leukocytes...
  4. pmc Role of MUC5AC in the pathogenesis of exercise-induced bronchoconstriction
    Teal S Hallstrand
    Department of Medicine, University of Washington, Seattle WA 98195 6522, USA
    J Allergy Clin Immunol 119:1092-8. 2007
    ....
  5. ncbi request reprint Aerobic conditioning in mild asthma decreases the hyperpnea of exercise and improves exercise and ventilatory capacity
    T S Hallstrand
    Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA 98195 8673, USA
    Chest 118:1460-9. 2000
    ..To determine the effect of an aerobic conditioning program on fitness, respiratory physiology, and resting lung function in patients with mild asthma...
  6. pmc Secreted phospholipase A2 group X overexpression in asthma and bronchial hyperresponsiveness
    Teal S Hallstrand
    Division of Pulmonary and Critical Care, Department of Medicine, University of Washington, Box 356522, Seattle, WA 98195, USA
    Am J Respir Crit Care Med 176:1072-8. 2007
    ..Secreted phospholipase A(2) enzymes (sPLA(2)s) play key regulatory roles in the biosynthesis of eicosanoids, such as the cysteinyl leukotrienes, but the role of these enzymes in the pathogenesis of asthma is not known...
  7. ncbi request reprint Role of leukotrienes in exercise-induced bronchoconstriction
    Teal S Hallstrand
    Division of Pulmonary and Critical Care, University of Washington, Seattle, WA 98195, USA
    Curr Allergy Asthma Rep 9:18-25. 2009
    ..Therapies that block cysLT production or the cysLT(1) receptor effectively reduce the severity of EIB...
  8. doi request reprint Initial test of the seattle asthma severity and control questionnaire: a multidimensional assessment of asthma severity and control
    Teal S Hallstrand
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    Ann Allergy Asthma Immunol 103:225-32. 2009
    ..The Seattle Asthma Severity and Control Questionnaire (SASCQ) was designed as a short, sensitive, and quantitative measure of asthma severity, impairment, and risk...
  9. pmc Transglutaminase 2, a novel regulator of eicosanoid production in asthma revealed by genome-wide expression profiling of distinct asthma phenotypes
    Teal S Hallstrand
    Division of Pulmonary and Critical Care, Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 5:e8583. 2010
    ..The objective of this study was to identify genes differentially expressed in EIB and to understand the function of these genes in the biology of asthma...
  10. pmc Genetic pleiotropy between asthma and obesity in a community-based sample of twins
    Teal S Hallstrand
    Department of Medicine, University of Washington, Seattle, 98195, USA
    J Allergy Clin Immunol 116:1235-41. 2005
    ..Asthma and obesity are common conditions that are strongly associated. This association might be due to shared genetic or environmental causes...
  11. pmc Airway immunopathology of asthma with exercise-induced bronchoconstriction
    Teal S Hallstrand
    Department of Medicine, Division of Pulmonary and Critical Care, University of Washington, Seattle, WA 98195, USA
    J Allergy Clin Immunol 116:586-93. 2005
    ..The pathobiology that makes this group of asthmatic subjects susceptible to bronchoconstriction after a brief period of exercise remains poorly understood...
  12. ncbi request reprint Practical management of acute asthma in adults
    Teal S Hallstrand
    Division of Pulmonary and Critical Care Medicine, University of Washington, Box 356522, Seattle WA 98195 6522, USA
    Respir Care 47:171-82. 2002
    ..After an episode of acute asthma, long-term preventive medications, especially inhaled corticosteroids, should be prescribed and education should be provided to prevent future episodes...
  13. ncbi request reprint Leukotriene modifiers
    Teal S Hallstrand
    Division of Pulmonary and Critical Medicine, University of Washington, Box 356522, 1959 NE Pacific Street, Seattle, WA 98195 6588, USA
    Med Clin North Am 86:1009-33, vi. 2002
    ..LT modifiers are effective in the treatment of exercise-induced bronchoconstriction and aspirin-induced asthma. There are few adverse effects of LT modifiers...
  14. pmc Quality of life in adolescents with mild asthma
    Teal S Hallstrand
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, Seattle, Washington 98195 6522, USA
    Pediatr Pulmonol 36:536-43. 2003
    ..Symptoms of dyspnea during exercise are common in asthma and are associated with lower HRQoL. The clinical significance of these differences in HRQoL is unclear...
  15. ncbi request reprint The role of allergy in manifestations of respiratory disease in adult cystic fibrosis
    Teal S Hallstrand
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, Washington 98195 6522, USA
    Ann Allergy Asthma Immunol 92:228-33. 2004
    ..Variability is present in the expression of the clinical phenotype in cystic fibrosis (CF). Part of this variability may be explained by the coexistence of allergy in CF...
  16. ncbi request reprint Inhaled IFN-gamma for persistent nontuberculous mycobacterial pulmonary disease due to functional IFN-gamma deficiency
    T S Hallstrand
    Division of Pulmonary and Critical Care, Dept of Medicine, University of Washington, Box 356522, 1959 NE Pacific Street, Seattle, WA, 98195, USA
    Eur Respir J 24:367-70. 2004
    ..In conclusion, inhaled interferon-gamma can be effective for the treatment of nontuberculous mycobacteria pulmonary disease associated with functional interferon-gamma deficiency...
  17. pmc Inflammatory basis of exercise-induced bronchoconstriction
    Teal S Hallstrand
    Department of Medicine, Division of Pulmonary and Critical Care, University of Washington, Seattle, Washington 98195 6522, USA
    Am J Respir Crit Care Med 172:679-86. 2005
    ..Exercise-induced bronchoconstriction (EIB) is a highly prevalent condition with unclear pathogenesis. Two competing theories of the pathogenesis of EIB differ regarding the inflammatory basis of this condition...
  18. pmc Safety of sputum induction with hypertonic saline solution in exercise-induced bronchoconstriction
    Chris Carlsten
    Division of Pulmonary and Critical Care, Department of Medicine, University of Washington, Seattle, WA 98195, USA
    Chest 131:1339-44. 2007
    ..The safety of sputum induction (SI) is well described in stable asthma, but the safety of SI in exercise-induced bronchoconstriction (EIB) has not been established...
  19. ncbi request reprint Effectiveness of screening examinations to detect unrecognized exercise-induced bronchoconstriction
    Teal S Hallstrand
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, The School of Public Health and Community Medicine, University of Washington, Seattle 98195, USA
    J Pediatr 141:343-8. 2002
    ....
  20. pmc PKR-dependent CHOP induction limits hyperoxia-induced lung injury
    Tricia I Lozon
    Center for Lung Biology, University of Washington, Seattle, USA
    Am J Physiol Lung Cell Mol Physiol 300:L422-9. 2011
    ..We conclude that hyperoxia increases CHOP expression via an ER stress-independent, PKR-dependent pathway and that increased CHOP expression protects against hyperoxia-induced lung injury...
  21. ncbi request reprint Long-term acquisition of allergen-specific IgE and asthma following allogeneic bone marrow transplantation from allergic donors
    Teal S Hallstrand
    Department of Medicine, University of Washington, BB 1333 Health Sciences, Box 356523, 1959 NE Pacific St, Seattle, WA 98195 6523, USA
    Blood 104:3086-90. 2004
    ..We conclude that marrow-derived immune cells from allergic donors can transfer the predisposition to allergy and asthma...
  22. pmc An update on the role of leukotrienes in asthma
    Teal S Hallstrand
    University of Washington, Seattle, USA
    Curr Opin Allergy Clin Immunol 10:60-6. 2010
    ..We review recent findings on regulation of leukotriene synthesis, biological function of leukotrienes in disease models, and use of leukotriene modifiers in clinical practice...
  23. pmc Improved sensitivity mass spectrometric detection of eicosanoids by charge reversal derivatization
    James G Bollinger
    Department of Chemistry, University of Washington, Seattle, Washington 98195, USA
    Anal Chem 82:6790-6. 2010
    ..One can anticipate that the AMPP derivatization method can be extended to other carboxylic acid analytes for enhanced sensitivity detection...
  24. pmc Effects of bronchoconstriction, minute ventilation, and deep inspiration on the composition of exhaled breath condensate
    Jason S Debley
    Department of Pediatrics, Division of Pulmonary Medicine, University of Washington, Seattle, WA 98195, USA
    Chest 139:16-22. 2011
    ..The goal of this study was to determine if the composition of EBC is affected by changes in airway caliber, minute ventilation, or forceful exhalation, factors that may differ among subjects with asthma in cross-sectional studies...
  25. pmc Health care use and quality of life among patients with asthma and panic disorder
    Jonathan M Feldman
    Ferkauf Graduate School of Psychology and Albert Einstein College of Medicine, Yeshiva University, Rousso Building, 1300 Morris Park Ave, Bronx, NY 10461, USA
    J Asthma 42:179-84. 2005
    ..These findings indicate a need to develop interventions to improve quality of life and self-management of asthma among PD patients...
  26. ncbi request reprint Methods to improve measurement of cysteinyl leukotrienes in exhaled breath condensate from subjects with asthma and healthy controls
    Jason S Debley
    J Allergy Clin Immunol 120:1216-7. 2007

Research Grants3

  1. Secretory Phospholipase A2s in Airway Pathophysiology
    Teal S Hallstrand; Fiscal Year: 2010
    ..Our goal is to determine the function of the sPLA2s in asthma so that novel therapies can be developed and tested in clinical trials that will improve the effectiveness of asthma treatments and alter the natural history of asthma. ..