Matthew R Grimmer

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Childhood tumors of the nervous system as disorders of normal development
    Matthew R Grimmer
    Department of Neurology, University of California, San Francisco, CA 94143, USA
    Curr Opin Pediatr 18:634-8. 2006
  2. pmc Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC
    Fredrik J Swartling
    University of California, Department of Neurology, Brain Tumor Research Center and Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94158, USA
    Cancer Cell 21:601-13. 2012
  3. pmc Pleiotropic role for MYCN in medulloblastoma
    Fredrik J Swartling
    University of California at San Francisco, San Francisco, California 94158, USA
    Genes Dev 24:1059-72. 2010
  4. pmc BMPs oppose Math1 in cerebellar development and in medulloblastoma
    Matthew R Grimmer
    Department of Neurology, University of California at San Francisco, San Francisco, California 94143, USA
    Genes Dev 22:693-9. 2008

Detail Information

Publications4

  1. ncbi Childhood tumors of the nervous system as disorders of normal development
    Matthew R Grimmer
    Department of Neurology, University of California, San Francisco, CA 94143, USA
    Curr Opin Pediatr 18:634-8. 2006
    ..We provide a detailed discussion of two pediatric neural tumors, medulloblastoma and neuroblastoma, addressing tumorigenic causality and similarities within a pharmacological context...
  2. pmc Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC
    Fredrik J Swartling
    University of California, Department of Neurology, Brain Tumor Research Center and Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94158, USA
    Cancer Cell 21:601-13. 2012
    ..These differences were regulated in part by the transcription factor SOX9, activated in the SHH subclass of human medulloblastoma. Our results demonstrate context-dependent transformation of NSCs in response to a common oncogenic signal...
  3. pmc Pleiotropic role for MYCN in medulloblastoma
    Fredrik J Swartling
    University of California at San Francisco, San Francisco, California 94158, USA
    Genes Dev 24:1059-72. 2010
    ..Targeted expression of MYCN thus contributes to initiation, progression, and maintenance of MB, suggesting a central role for MYCN in pathogenesis...
  4. pmc BMPs oppose Math1 in cerebellar development and in medulloblastoma
    Matthew R Grimmer
    Department of Neurology, University of California at San Francisco, San Francisco, California 94143, USA
    Genes Dev 22:693-9. 2008