S L Greenspan
Affiliation: University of Pittsburgh
- Early changes in serum N-telopeptide and C-telopeptide cross-linked collagen type 1 predict long-term response to alendronate therapy in elderly womenS L Greenspan
Department of Medicine, University of Pittsburgh Medical Center, Pennsylvania 15213, USA
J Clin Endocrinol Metab 85:3537-40. 2000..05). We conclude that early changes in serum NTx and CTx, markers of bone resorption, predict long-term changes in vertebral BMD in elderly women receiving alendronate therapy and provide a useful tool to assess skeletal health...
- Clinical performance of a highly portable, scanning calcaneal ultrasonometerS L Greenspan
Divisions of Endocrinology and Metabolism, and Geriatric Medicine, University of Pittsburgh Medical Center, 1110 Kaufmann Building, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
Osteoporos Int 12:391-8. 2001..We conclude that the QUS-2 calcaneal ultrasonometer exhibits reproducible clinical performance that is similar to BMD of the spine and hip in identifying women with low bone mass and discriminating women with fracture from those without...
- The effect of risedronate on hip structural geometry in chemotherapy-induced postmenopausal women with or without use of aromatase inhibitors: a 2-year trialG J van Londen
Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Bone 46:655-9. 2010..Our objectives were to (1) examine the impact of AIs and no-AIs on hip structural geometry (HSA) of chemotherapy-induced postmenopausal women, and (2) determine if oral bisphosphonates could affect these changes...
- Evaluation of ability of biochemical markers of bone turnover to predict a response to increased doses of HRTH N Rosen
Charles A Dana Research Institute and the Harvard Thorndike Laboratory of the Beth Israel Deaconess Medical Center, Department of Medicine, Division of Endocrinology, Harvard Medical School, Boston, MA 02215, USA
Calcif Tissue Int 74:415-23. 2004..Measuring of bone density and bone turnover with better precision might be more successful in guiding individual dosing of antiresorptive therapy...
- The impact of an aromatase inhibitor on body composition and gonadal hormone levels in women with breast cancerG J van Londen
Medicine, University of Pittsburgh, Kaufmann Medical Bldg, Pittsburgh, PA, 15213, USA
Breast Cancer Res Treat 125:441-6. 2011..The mechanisms and implications of these changes need to be studied further...
- Classification of osteoporosis and osteopenia in men is dependent on site-specific analysisS A Stoch
Division of Bone and Mineral Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
J Clin Densitom 3:311-7. 2000..We conclude depending on the number and selection of sites there is considerable variability in the classification and misclassification of osteoporosis and osteopenia in men...
- Prevention of bone loss with risedronate in breast cancer survivors: a randomized, controlled clinical trialS L Greenspan
Department of Medicine, University of Pittsburgh, 3471 Fifth Ave, Suite 1110, Kaufmann Bldg, Pittsburgh, PA, 15213, USA
Osteoporos Int 26:1857-64. 2015..Women with the greatest decreases in bone turnover markers at 12 months had the greatest increases in bone density at 24 months...
- Practical clinical application of biochemical markers of bone turnover: Consensus of an expert panelP D Miller
Department of Medicine, University of Colorado Health Sciences Center and Colorado Center for Bone Research, Denver, CO 80227, USA
J Clin Densitom 2:323-42. 1999..We will describe, in practical terms, how bone markers can be appropriately incorporated into clinical practice today...
- Bone loss in men with prostate cancer treated with gonadotropin-releasing hormone agonistsS A Stoch
Division of Bone and Mineral Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
J Clin Endocrinol Metab 86:2787-91. 2001..In conclusion, men with prostate cancer receiving androgen deprivation therapy have a significant decrease in bone mass and increase in bone turnover, thus placing them at increased risk of fracture...
- Instant vertebral assessment: a noninvasive dual X-ray absorptiometry technique to avoid misclassification and clinical mismanagement of osteoporosisS L Greenspan
University of Pittsburgh Medical Center, Osteoporosis Prevention and Treatment Center, Lilliane S Kaufmann Medical Building, Suite 1110, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
J Clin Densitom 4:373-80. 2001..We conclude that IVA is a useful adjunct in the clinical identification of osteoporosis and may prevent mismanagement of osteoporotic patients...
- Short-term changes in bone turnover markers and bone mineral density response to parathyroid hormone in postmenopausal women with osteoporosisD C Bauer
Department of Medicine, University of California San Francisco Coordinating Center, 185 Berry 5700, San Francisco, CA 94107, USA
J Clin Endocrinol Metab 91:1370-5. 2006..Treatment of osteoporotic women with PTH increases biochemical markers of bone turnover, increases axial bone mineral density (BMD), and reduces fracture risk...
- The effect of moderate impact exercise on skeletal integrity in master athletesN F Velez
Department of Medicine, Osteoporosis Center, University of Pittsburgh, 1110 Kaufmann Medical Building, 3471 Fifth Ave, Pittsburgh, PA 15213, USA
Osteoporos Int 19:1457-64. 2008..Total body BMD was greatest among runners suggesting that moderate impact activities continue to play a role in maintaining skeletal integrity with age...
- Effect of risedronate on hip structural geometry: a 1-year, double-blind trial in chemotherapy-induced postmenopausal womenG J van Londen
Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Bone 43:274-8. 2008..The effect on structural geometry is unknown. Our objective was to determine if oral bisphosphonate therapy could maintain or improve femoral geometry in breast cancer patients with chemotherapy-induced menopause...
- Factors associated with diagnosis and treatment of osteoporosis in older adultsS Nayak
School of Medicine, Department of Medicine, Division of General Internal Medicine, Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh, Pittsburgh, PA, USA
Osteoporos Int 20:1963-7. 2009..Individuals with several risk factors, including older age, were not more likely to be diagnosed or treated. Measures should be taken to improve osteoporosis identification and treatment in high-risk patients...
- Vitamin D deficiency is associated with functional decline and falls in frail elderly women despite supplementationM P Kotlarczyk
Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh, 1110 Kaufmann Medical Building, 3471 Fifth Avenue, Pittsburgh, PA, 15213, USA
Osteoporos Int . 2016..Initial vitamin D deficiency was associated with greater functional decline and increased fall risk despite guideline-recommended supplementation, highlighting the importance of preventing vitamin D deficiency in frail elderly...
- Uncoupling of bone turnover following hip replacementH Whitson
Department of Medicine, Duke University Medical Center, Durham, NC, USA
Calcif Tissue Int 71:14-9. 2002..Longer periods of follow-up are needed to assess long-term bone mass changes...