D T Graves

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Animal models to study host-bacteria interactions involved in periodontitis
    Dana T Graves
    Department of Periodontics, University of Pennsylvania, Philadelphia, PA, USA
    Front Oral Biol 15:117-32. 2012
  2. pmc Role of forkhead transcription factors in diabetes-induced oxidative stress
    Bhaskar Ponugoti
    School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104 6030, USA
    Exp Diabetes Res 2012:939751. 2012
  3. pmc Effect of bacteria on the wound healing behavior of oral epithelial cells
    Rupa Bhattacharya
    Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 9:e89475. 2014
  4. pmc P. gingivalis modulates keratinocytes through FOXO transcription factors
    Shuai Li
    Department of Implant Dentistry, Peking University, School and Hospital of Stomatology, Beijing, China Departments of Pathology and Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 8:e78541. 2013
  5. pmc Abnormal cell responses and role of TNF-α in impaired diabetic wound healing
    Fanxing Xu
    School of Life Science and Biotechnology, Dalian University of Technology, Dalian 116024, China
    Biomed Res Int 2013:754802. 2013
  6. pmc Diabetes aggravates periodontitis by limiting repair through enhanced inflammation
    Sandra Pacios
    Department of Periodontics, University of Pennsylvania, 240 S 40th St, Levy 122, Philadelphia, PA 19104, USA
    FASEB J 26:1423-30. 2012
  7. pmc Inflammation and uncoupling as mechanisms of periodontal bone loss
    D T Graves
    Department of Periodontics, School of Dental Medicine, University of Pennsylvania, USA
    J Dent Res 90:143-53. 2011
  8. ncbi request reprint Clinical, radiographic and biochemical assessment of IL-1/TNF-alpha antagonist inhibition of bone loss in experimental periodontitis
    T W Oates
    Department of Periodontics, University of Texas Health Science Center at San Antonio, TX 78229, USA
    J Clin Periodontol 29:137-43. 2002
  9. pmc Effect of Aging on Periodontal Inflammation, Microbial Colonization, and Disease Susceptibility
    Y Wu
    State Key Laboratory of Oral Disease, West China Hospital of Stomatology, Sichuan University, Chengdu, China Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA
    J Dent Res 95:460-6. 2016
  10. pmc Gene expression dynamics during diabetic periodontitis
    O M Andriankaja
    Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA
    J Dent Res 91:1160-5. 2012

Collaborators

Detail Information

Publications12

  1. pmc Animal models to study host-bacteria interactions involved in periodontitis
    Dana T Graves
    Department of Periodontics, University of Pennsylvania, Philadelphia, PA, USA
    Front Oral Biol 15:117-32. 2012
    ..Thus, each of the models described below can be adapted to test discrete components of the pathological process of periodontal disease, but not necessarily all of them...
  2. pmc Role of forkhead transcription factors in diabetes-induced oxidative stress
    Bhaskar Ponugoti
    School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104 6030, USA
    Exp Diabetes Res 2012:939751. 2012
    ..They are induced by oxidative stress and contribute to ROS-induced cell damage and apoptosis. In this paper, we discuss the role of FOXO transcription factors in mediating oxidative stress-induced cellular response...
  3. pmc Effect of bacteria on the wound healing behavior of oral epithelial cells
    Rupa Bhattacharya
    Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 9:e89475. 2014
    ..05) that are critical for GI/S transition. Further, genes associated with cell migration such as integrin beta-3 and -6 were significantly downregulated by P. gingivalis (p<0.05)...
  4. pmc P. gingivalis modulates keratinocytes through FOXO transcription factors
    Shuai Li
    Department of Implant Dentistry, Peking University, School and Hospital of Stomatology, Beijing, China Departments of Pathology and Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 8:e78541. 2013
    ..In addition, a new function for FOXO1 was identified, that of suppressing TLR-2 and TLR-4 and maintaining integrin beta -1, beta -3 and beta -6 basal mRNA levels in keratinocytes. ..
  5. pmc Abnormal cell responses and role of TNF-α in impaired diabetic wound healing
    Fanxing Xu
    School of Life Science and Biotechnology, Dalian University of Technology, Dalian 116024, China
    Biomed Res Int 2013:754802. 2013
    ..Diabetes-enhanced and prolonged expression of TNF- α also contributes to impaired healing. In this paper, we discuss the abnormal cell responses in diabetic wound healing and the contribution of TNF- α ...
  6. pmc Diabetes aggravates periodontitis by limiting repair through enhanced inflammation
    Sandra Pacios
    Department of Periodontics, University of Pennsylvania, 240 S 40th St, Levy 122, Philadelphia, PA 19104, USA
    FASEB J 26:1423-30. 2012
    ..Thus, diabetes prolongs inflammation and osteoclastogenesis in periodontitis and through TNF limits the normal reparative process by negatively modulating factors that regulate bone...
  7. pmc Inflammation and uncoupling as mechanisms of periodontal bone loss
    D T Graves
    Department of Periodontics, School of Dental Medicine, University of Pennsylvania, USA
    J Dent Res 90:143-53. 2011
    ....
  8. ncbi request reprint Clinical, radiographic and biochemical assessment of IL-1/TNF-alpha antagonist inhibition of bone loss in experimental periodontitis
    T W Oates
    Department of Periodontics, University of Texas Health Science Center at San Antonio, TX 78229, USA
    J Clin Periodontol 29:137-43. 2002
    ....
  9. pmc Effect of Aging on Periodontal Inflammation, Microbial Colonization, and Disease Susceptibility
    Y Wu
    State Key Laboratory of Oral Disease, West China Hospital of Stomatology, Sichuan University, Chengdu, China Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA
    J Dent Res 95:460-6. 2016
    ..gingivalis colonization following inoculation and increased periodontal disease susceptibility, reflected by higher TNF levels and osteoclast numbers in the periodontium of aged versus young mice. ..
  10. pmc Gene expression dynamics during diabetic periodontitis
    O M Andriankaja
    Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA
    J Dent Res 91:1160-5. 2012
    ....
  11. pmc Altered fibroblast proliferation and apoptosis in diabetic gingival wounds
    T Desta
    Department of Periodontics, NJDS UMDNJ, 110 Bergen Street, Newark, NJ 07101 1709, USA
    J Dent Res 89:609-14. 2010
    ..05). The results suggest that diabetes may decrease fibroblast numbers through increased apoptosis and reduced proliferation, both of which may be mediated through increased activation of FOXO1...