Affiliation: University of California
- Coarse-grained modeling study of nonpeptide RGD ligand density and PEG molecular weight on the conformation of poly(γ-glutamyl-glutamate) paclitaxel conjugatesLili X Peng
Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA
J Mol Model 17:2973-87. 2011..These results indicate that the PGG-PTX-PEG1000-npRGD(4) and PGG-PTX-PEG1000-npRGD(8) molecules are the most efficacious candidates and are further recommended for experimental preclinical studies...
- Function of an implanted tissue glucose sensor for more than 1 year in animalsDavid A Gough
Department of Bioengineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0412, USA
Sci Transl Med 2:42ra53. 2010..These results represent a milestone in the translation of the sensor system to human applications...
- Employment and career prospects for bioengineersDavid Gough
Department of Bioengineering, University of California San Diego, La Jolla, CA 92093 0412, USA
Nat Biotechnol 20:635-6. 2002
- Frequency characterization of blood glucose dynamicsDavid A Gough
Department of Bioengineering, University of California San Diego, San Diego, CA, USA
Ann Biomed Eng 31:91-7. 2003..This analysis provides key information for the design of clinical studies that include blood glucose dynamics and for the design of new glucose monitoring systems...
- Blood glucose dynamicsFarbod N Rahaghi
Department of Bioengineering, University of California San Diego, La Jolla, California 92093 0412, USA
Diabetes Technol Ther 10:81-94. 2008..An example of new insights is the observation that there are four time scales of blood glucose variations in individuals without diabetes, and these time scales are modified or lost in diabetes...
- Tissue window chamber system for validation of implanted oxygen sensorsMilan T Makale
Department of Bioengineering, University of California San Diego, La Jolla 92093 0412, USA
Am J Physiol Heart Circ Physiol 284:H2288-94. 2003..Examples are given of sensor recordings and images of tissues with implanted oxygen sensor arrays...
- Mass transfer and gas-phase calibration of implanted oxygen sensorsMilan T Makale
Department of Bioengineering, University of California San Diego, La Jolla, California 92093, USA
Anal Chem 76:1773-7. 2004..This method provides a bridge between the complementary approaches of empirical calibration and model-based calculation for determining oxygen concentration from the sensor response...
- Variants of the tissue-sensor array window chamberMilan T Makale
Dept of Bioengineering, Univ of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0412, USA
Am J Physiol Heart Circ Physiol 289:H57-65. 2005..These observations suggest new strategies for sensor design and operation. Window chamber variants are important tools for validation of implanted sensors...
- INFRASTRUCTURE OF BIOENGINEERING DEVELOPMENTDavid Gough; Fiscal Year: 2002..This is necessary to develop biomedical engineering at UCSD to its full potential and to provide a model of bioengineering education and research for the nation. ..
- Validation of Long-Term Glucose Sensor in TissuesDavid Gough; Fiscal Year: 2007..This project will further validate an implantable glucose sensor that will provide a basis for reliable detection of hypoglycemia and automatic insulin administration. [unreadable] [unreadable] [unreadable]..
- Modeling Mass Transfer to Active Implants for DiabetesDavid Gough; Fiscal Year: 2009..This project will examine the permeability of tissues surrounding implanted devices to assess substrate supply to the implant. This information may accelerate implementation of these therapies. ..