Cynthia L Gay

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Antiretrovirals to prevent HIV infection: pre- and postexposure prophylaxis
    Cynthia L Gay
    Division of Infectious Disease, University of North Carolina at Chapel Hill, 130 Mason Farm Road, CB 7030, Chapel Hill, NC 27599, USA
    Curr Infect Dis Rep 10:323-31. 2008
  2. pmc Efficacy of NNRTI-based antiretroviral therapy initiated during acute HIV infection
    Cynthia L Gay
    University of North Carolina at Chapel Hill, NC 27599, USA
    AIDS 25:941-9. 2011
  3. pmc Acute HIV infection among pregnant women in Malawi
    Cynthia L Gay
    Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7030, USA
    Diagn Microbiol Infect Dis 66:356-60. 2010
  4. pmc Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy
    Cynthia Gay
    Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
    PLoS ONE 6:e19617. 2011
  5. pmc Fixed-dose combination emtricitabine/tenofovir/efavirenz initiated during acute HIV infection; 96-week efficacy and durability
    Cynthia L Gay
    aDepartment of Medicine, UNC Institute for Global Health and Infectious Diseases bDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill cDepartment of Medicine, Division of Infectious Diseases dDepartment of Surgery eDuke Human Vaccine Institute, Duke University, Durham fLaboratory Corporation of America, Burlington, North Carolina gDepartment of Clinical Medicine, University of San Diego, San Diego, California, USA
    AIDS 30:2815-2822. 2016
  6. pmc Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies
    Amanda M Crooks
    Department of Medicine, University of North Carolina at Chapel Hill
    J Infect Dis 212:1361-5. 2015
  7. pmc Antiretroviral therapy initiated during acute HIV infection fails to prevent persistent T-cell activation
    Michael J Vinikoor
    Department of Medicine, Center for Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Acquir Immune Defic Syndr 62:505-8. 2013
  8. pmc Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection
    Nancie M Archin
    Department of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA
    Proc Natl Acad Sci U S A 109:9523-8. 2012
  9. pmc Ten Years of Screening and Testing for Acute HIV Infection in North Carolina
    Joann D Kuruc
    Division of Infectious Disease, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC Division of Public Health, North Carolina Department of Health and Human Services, Raleigh, NC and Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC
    J Acquir Immune Defic Syndr 71:111-9. 2016
  10. doi request reprint The detection of acute HIV infection
    Myron S Cohen
    Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7030, USA
    J Infect Dis 202:S270-7. 2010

Collaborators

Detail Information

Publications15

  1. pmc Antiretrovirals to prevent HIV infection: pre- and postexposure prophylaxis
    Cynthia L Gay
    Division of Infectious Disease, University of North Carolina at Chapel Hill, 130 Mason Farm Road, CB 7030, Chapel Hill, NC 27599, USA
    Curr Infect Dis Rep 10:323-31. 2008
    ..The prevention benefits of ART may begin to affect the decision of when to start therapy and add a much-needed strategy to current HIV prevention efforts...
  2. pmc Efficacy of NNRTI-based antiretroviral therapy initiated during acute HIV infection
    Cynthia L Gay
    University of North Carolina at Chapel Hill, NC 27599, USA
    AIDS 25:941-9. 2011
    ..Characterize responses to non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral treatment (ART) initiated during acute HIV infection (AHI)...
  3. pmc Acute HIV infection among pregnant women in Malawi
    Cynthia L Gay
    Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7030, USA
    Diagn Microbiol Infect Dis 66:356-60. 2010
    ..Dual HIV rapid tests have high sensitivity and specificity. HIV testing should be repeated in the third trimester and/or at delivery...
  4. pmc Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy
    Cynthia Gay
    Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
    PLoS ONE 6:e19617. 2011
    ..We studied subjects with AHI prospectively to develop better treatment and public health interventions...
  5. pmc Fixed-dose combination emtricitabine/tenofovir/efavirenz initiated during acute HIV infection; 96-week efficacy and durability
    Cynthia L Gay
    aDepartment of Medicine, UNC Institute for Global Health and Infectious Diseases bDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill cDepartment of Medicine, Division of Infectious Diseases dDepartment of Surgery eDuke Human Vaccine Institute, Duke University, Durham fLaboratory Corporation of America, Burlington, North Carolina gDepartment of Clinical Medicine, University of San Diego, San Diego, California, USA
    AIDS 30:2815-2822. 2016
    ..Updated guidelines recommend immediate antiretroviral treatment (ART) during acute HIV infection (AHI), but efficacy data on regimens during AHI are limited...
  6. pmc Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies
    Amanda M Crooks
    Department of Medicine, University of North Carolina at Chapel Hill
    J Infect Dis 212:1361-5. 2015
    ..When QVOA is performed in this format, RCI decreases of >6-fold were rare. We suggest that a 6-fold decline is a relevant threshold to reliably identify effects of antilatency interventions on RCI...
  7. pmc Antiretroviral therapy initiated during acute HIV infection fails to prevent persistent T-cell activation
    Michael J Vinikoor
    Department of Medicine, Center for Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Acquir Immune Defic Syndr 62:505-8. 2013
    ..9%, P = 0.008). Shorter time to suppression predicted lower activation at 96 weeks. These results support the hypothesis that very early events in HIV-1 pathogenesis may result in prolonged immune dysfunction...
  8. pmc Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection
    Nancie M Archin
    Department of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA
    Proc Natl Acad Sci U S A 109:9523-8. 2012
    ..These findings reinforce and extend the concept that new approaches will be needed to eradicate HIV infection, and, in particular, highlight the need to target the extremely small but universal, long-lived latent reservoir...
  9. pmc Ten Years of Screening and Testing for Acute HIV Infection in North Carolina
    Joann D Kuruc
    Division of Infectious Disease, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC Division of Public Health, North Carolina Department of Health and Human Services, Raleigh, NC and Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC
    J Acquir Immune Defic Syndr 71:111-9. 2016
    ..To describe demographic and behavioral characteristics of persons with acute HIV infection (AHI) over time...
  10. doi request reprint The detection of acute HIV infection
    Myron S Cohen
    Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7030, USA
    J Infect Dis 202:S270-7. 2010
    ..We conclude that further technical advances are essential to allow more widespread detection of patients with AHI and to affect HIV treatment outcomes and transmission prevention...
  11. pmc Ongoing HIV Transmission and the HIV Care Continuum in North Carolina
    Anna B Cope
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS ONE 10:e0127950. 2015
    ..We analyzed these attributes of named partners of persons with acute HIV infection (index AHI cases) to characterize the transmission landscape in North Carolina (NC)...
  12. doi request reprint Prospective study of the ARCHITECTHIV Ag/Ab Combo fourth generation assay to detect HIV infection in sexually transmitted infection clinics
    Jason J Bischof
    University of North Carolina at Chapel Hill, USA
    AIDS 25:1927-9. 2011
    ..In this setting, the assay reported a sensitivity of 100%, a specificity of 99.9%, and a median turn-around time of 26.1 h...
  13. pmc Treatment to prevent transmission of HIV-1
    Myron S Cohen
    University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7030, USA
    Clin Infect Dis 50:S85-95. 2010
    ..In this article, we review the data supporting the use of ART to prevent HIV transmission and critically examine the public health implications of this strategy...
  14. doi request reprint Detecting HIV among persons accompanying patients to an infectious diseases clinic
    Jason J Bischof
    From the Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC
    Sex Transm Dis 42:54-6. 2015
    ..Infectious diseases (ID) clinics are locations where members of at risk social networks, including sex partners of HIV-infected patients, make contact with a medical care setting when they accompany HIV-positive patients to appointments...
  15. ncbi request reprint Advanced immunosuppression at entry to HIV care in the southeastern United States and associated risk factors
    Cynthia L Gay
    The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    AIDS 20:775-8. 2006
    ..Male sex was an independent predictor in multivariable analysis. These results indicate an urgent need to increase HIV testing for earlier diagnosis in the southeastern USA...