Anand K Ganesan

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Broad spectrum identification of SUMO substrates in melanoma cells
    Anand K Ganesan
    Department of Dermatology, University of California, Irvine, CA 92697 2400, USA
    Proteomics 7:2216-21. 2007
  2. pmc Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells
    Anand K Ganesan
    Department of Dermatology, University of California Irvine, Irvine, California, United States of America
    PLoS Genet 4:e1000298. 2008
  3. pmc Protein interaction network topology uncovers melanogenesis regulatory network components within functional genomics datasets
    Hsiang Ho
    Department of Biological Chemistry, University of California, Irvine, 92697 1700, USA
    BMC Syst Biol 4:84. 2010
  4. pmc 9-cis retinoic acid is the ALDH1A1 product that stimulates melanogenesis
    Elyse K Paterson
    Department of Biological Chemistry, University of California, Irvine, CA 92697 2400, USA
    Exp Dermatol 22:202-9. 2013
  5. pmc RhoJ regulates melanoma chemoresistance by suppressing pathways that sense DNA damage
    Hsiang Ho
    Department of Dermatology, University of California at Irvine, Irvine, California 92697, USA
    Cancer Res 72:5516-28. 2012
  6. pmc RhoJ modulates melanoma invasion by altering actin cytoskeletal dynamics
    Hsiang Ho
    Department of Medicine, University of California, Irvine, Irvine, CA, USA
    Pigment Cell Melanoma Res 26:218-25. 2013
  7. doi request reprint The pleiotropic roles of autophagy regulators in melanogenesis
    Hsiang Ho
    Department of Dermatology and Biological Chemistry, University of California, Irvine, CA, USA
    Pigment Cell Melanoma Res 24:595-604. 2011
  8. pmc WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition
    Hsiang Ho
    Department of Biological Chemistry, University of California, Irvine, CA 92697 2400, USA
    J Biol Chem 286:12509-23. 2011
  9. pmc Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle
    Elyse K Paterson
    Department of Biological Chemistry, University of California Irvine, Irvine, CA, United States of America
    PLoS ONE 10:e0143702. 2015
  10. pmc Systems-level cancer gene identification from protein interaction network topology applied to melanogenesis-related functional genomics data
    Tijana Milenkovic
    Department of Computer Science, University of California, Irvine, CA 92697 3435, USA
    J R Soc Interface 7:423-37. 2010

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Broad spectrum identification of SUMO substrates in melanoma cells
    Anand K Ganesan
    Department of Dermatology, University of California, Irvine, CA 92697 2400, USA
    Proteomics 7:2216-21. 2007
    ..A proteomic SUMO target analysis in melanoma cells identified proteins involved in cellular signaling, growth control, and neural differentiation...
  2. pmc Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells
    Anand K Ganesan
    Department of Dermatology, University of California Irvine, Irvine, California, United States of America
    PLoS Genet 4:e1000298. 2008
    ....
  3. pmc Protein interaction network topology uncovers melanogenesis regulatory network components within functional genomics datasets
    Hsiang Ho
    Department of Biological Chemistry, University of California, Irvine, 92697 1700, USA
    BMC Syst Biol 4:84. 2010
    ..We experimentally validate our approach in the context of a recently completed RNAi screen to identify novel regulators of melanogenesis...
  4. pmc 9-cis retinoic acid is the ALDH1A1 product that stimulates melanogenesis
    Elyse K Paterson
    Department of Biological Chemistry, University of California, Irvine, CA 92697 2400, USA
    Exp Dermatol 22:202-9. 2013
    ....
  5. pmc RhoJ regulates melanoma chemoresistance by suppressing pathways that sense DNA damage
    Hsiang Ho
    Department of Dermatology, University of California at Irvine, Irvine, California 92697, USA
    Cancer Res 72:5516-28. 2012
    ..These findings identify DNA damage agents and pharmacologic inhibitors of RhoJ/PAK1 as novel synergistic agents that can be used to treat melanomas that are resistant to conventional chemotherapies...
  6. pmc RhoJ modulates melanoma invasion by altering actin cytoskeletal dynamics
    Hsiang Ho
    Department of Medicine, University of California, Irvine, Irvine, CA, USA
    Pigment Cell Melanoma Res 26:218-25. 2013
    ..Taken together, these observations identify RHOJ as a melanoma linchpin determinant that regulates both actin cytoskeletal dynamics and chemoresistance by activating PAK1...
  7. doi request reprint The pleiotropic roles of autophagy regulators in melanogenesis
    Hsiang Ho
    Department of Dermatology and Biological Chemistry, University of California, Irvine, CA, USA
    Pigment Cell Melanoma Res 24:595-604. 2011
    ....
  8. pmc WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition
    Hsiang Ho
    Department of Biological Chemistry, University of California, Irvine, CA 92697 2400, USA
    J Biol Chem 286:12509-23. 2011
    ..Taken together, our studies define a distinct role for WIPI1 and TORC1 signaling in controlling the transcription of melanogenic enzymes and melanosome maturation, a process that is distinct from starvation-induced autophagy...
  9. pmc Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle
    Elyse K Paterson
    Department of Biological Chemistry, University of California Irvine, Irvine, CA, United States of America
    PLoS ONE 10:e0143702. 2015
    ..These results indicate that color in skin and hair is determined not only by the total amount of melanin within the hair, but also by the relative accumulation of mature melanosomes. ..
  10. pmc Systems-level cancer gene identification from protein interaction network topology applied to melanogenesis-related functional genomics data
    Tijana Milenkovic
    Department of Computer Science, University of California, Irvine, CA 92697 3435, USA
    J R Soc Interface 7:423-37. 2010
    ..Understanding the underlying principles of this phenomenon is an open question, with a potential for increasing our understanding of complex diseases...