Adam J Funk
Affiliation: University of Alabama at Birmingham
- Decreased expression of NMDA receptor-associated proteins in frontal cortex of elderly patients with schizophreniaAdam J Funk
Departments of aNeurobiology bPsychiatry and Behavioral Neurobiology, University of Alabama, Birmingham, Alabama, USA
Neuroreport 20:1019-22. 2009..These data suggest that NMDA receptor complex formation, localization, and downstream signaling may be abnormal in schizophrenia...
- Abnormal activity of the MAPK- and cAMP-associated signaling pathways in frontal cortical areas in postmortem brain in schizophreniaAdam J Funk
Department of Neurobiology, University of Alabama Birmingham, Birmingham, AL 35294 0021, USA
Neuropsychopharmacology 37:896-905. 2012..Together with previous findings, these data suggest that abnormalities of intracellular signaling pathways may contribute to the pathophysiology of schizophrenia...
- Evidence for abnormal forward trafficking of AMPA receptors in frontal cortex of elderly patients with schizophreniaJohn C Hammond
Department of Neurobiology, University of Alabama Birmingham, 35294 0021, USA
Neuropsychopharmacology 35:2110-9. 2010..Together, these data suggest that there is an alteration of forward trafficking of AMPA receptors as well as changes in the subcellular localization of an AMPA receptor subunit in schizophrenia...
- Systematic evaluation of data-independent acquisition for sensitive and reproducible proteomics-a prototype design for a single injection assayMichael R Heaven
Vulcan Analytical, LLC, Birmingham, AL, 35203, USA
J Mass Spectrom 51:1-11. 2016..Our data show that extracted fragment-ion chromatograms are the reason DIA provides superior reproducibility. Copyright © 2015 John Wiley & Sons, Ltd. ..
- Lasting epigenetic influence of early-life adversity on the BDNF geneTania L Roth
Department of Neurobiology and the Evelyn F McKnight Brain Institute, University of Alabama Birmingham, Birmingham, Alabama 35294, USA
Biol Psychiatry 65:760-9. 2009..With a rat model of infant maltreatment by a caregiver, we investigated whether early-life adversity leaves lasting epigenetic marks at the brain-derived neurotrophic factor (BDNF) gene in the central nervous system...