David R Freyer

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Transition of care for young adult survivors of childhood and adolescent cancer: rationale and approaches
    David R Freyer
    LIFE Survivorship and Transition Program, Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, and Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    J Clin Oncol 28:4810-8. 2010
  2. doi request reprint Effects of sodium thiosulfate versus observation on development of cisplatin-induced hearing loss in children with cancer (ACCL0431): a multicentre, randomised, controlled, open-label, phase 3 trial
    David R Freyer
    Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles, Los Angeles, CA, USA Departments of Pediatrics and Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA Electronic address
    Lancet Oncol 18:63-74. 2017
  3. pmc Facilitating accrual to cancer control and supportive care trials: the clinical research associate perspective
    David Vanhoff
    Child Health Evaluative Sciences, Toronto, ON, Canada
    BMC Med Res Methodol 13:154. 2013
  4. pmc Children's Oncology Group's 2013 blueprint for research: adolescent and young adult oncology
    David R Freyer
    Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, CA 90027 6016, USA
    Pediatr Blood Cancer 60:1055-8. 2013
  5. pmc Postrelapse survival in childhood acute lymphoblastic leukemia is independent of initial treatment intensity: a report from the Children's Oncology Group
    David R Freyer
    Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles, CA, USA
    Blood 117:3010-5. 2011
  6. doi request reprint Pulmonary outcomes in patients with Hodgkin lymphoma treated with involved field radiation
    Rajkumar Venkatramani
    Division of Hematology Oncology, Children s Hospital Los Angeles, Los Angeles, California Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California
    Pediatr Blood Cancer 61:1277-81. 2014
  7. pmc Impact on survival and toxicity by duration of weight extremes during treatment for pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group
    Etan Orgel
    Etan Orgel, Jonathan Jaques Children s Cancer Center, Miller Children s Hospital, Long Beach Etan Orgel, Paul S Gaynon, and David R Freyer, Keck School of Medicine, University of Southern California Etan Orgel, Richard Sposto, Jemily Malvar, Paul S Gaynon, and David R Freyer, Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles Richard Sposto, University of Southern California, Los Angeles, CA Nita L Seibel, Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD and Elena Ladas, Center for Comprehensive Wellness, Columbia University, New York, NY
    J Clin Oncol 32:1331-7. 2014
  8. pmc Low Enrollment of Adolescents and Young Adults Onto Cancer Trials: Insights From the Community Clinical Oncology Program
    Michael E Roth
    Albert Einstein College of Medicine, Bronx, NY National Cancer Institute, Bethesda, MD Helen DeVos Children s Hospital at Spectrum Health, Grand Rapids, MI University of Texas Health Science Center at San Antonio, San Antonio, TX University of California, Davis and University of Southern California, Los Angeles, CA
    J Oncol Pract 12:e388-95. 2016
  9. doi request reprint Reconsidering Physical Activity Restrictions for Mononephric Survivors of Childhood Cancer: A Report From the Children's Oncology Group
    Maki Okada
    Miller Children s and Women s Hospital, Long Beach, CA, USA
    J Pediatr Oncol Nurs 33:306-13. 2016
  10. pmc Limitations of body mass index to assess body composition due to sarcopenic obesity during leukemia therapy
    Etan Orgel
    a Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles, Los Angeles, CA, USA
    Leuk Lymphoma . 2016

Detail Information

Publications19

  1. pmc Transition of care for young adult survivors of childhood and adolescent cancer: rationale and approaches
    David R Freyer
    LIFE Survivorship and Transition Program, Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, and Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    J Clin Oncol 28:4810-8. 2010
    ....
  2. doi request reprint Effects of sodium thiosulfate versus observation on development of cisplatin-induced hearing loss in children with cancer (ACCL0431): a multicentre, randomised, controlled, open-label, phase 3 trial
    David R Freyer
    Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles, Los Angeles, CA, USA Departments of Pediatrics and Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA Electronic address
    Lancet Oncol 18:63-74. 2017
    ..The primary aim of this study was to assess sodium thiosulfate for prevention of cisplatin-induced hearing loss in children and adolescents...
  3. pmc Facilitating accrual to cancer control and supportive care trials: the clinical research associate perspective
    David Vanhoff
    Child Health Evaluative Sciences, Toronto, ON, Canada
    BMC Med Res Methodol 13:154. 2013
    ..Our objective was to identify facilitators and perceived barriers to successful Children's Oncology Group (COG) CCL accrual from the clinical research associate (CRA) perspective...
  4. pmc Children's Oncology Group's 2013 blueprint for research: adolescent and young adult oncology
    David R Freyer
    Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, CA 90027 6016, USA
    Pediatr Blood Cancer 60:1055-8. 2013
    ..This experience will be useful in leveraging the new United States National Cancer Institute Clinical Trials Network to transform AYA Oncology research...
  5. pmc Postrelapse survival in childhood acute lymphoblastic leukemia is independent of initial treatment intensity: a report from the Children's Oncology Group
    David R Freyer
    Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles, CA, USA
    Blood 117:3010-5. 2011
    ..This study is registered at www.clinicaltrials.gov as NCT00002812...
  6. doi request reprint Pulmonary outcomes in patients with Hodgkin lymphoma treated with involved field radiation
    Rajkumar Venkatramani
    Division of Hematology Oncology, Children s Hospital Los Angeles, Los Angeles, California Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California
    Pediatr Blood Cancer 61:1277-81. 2014
    ..The purpose of this study is to describe the prevalence of pulmonary complications in HL patients treated using contemporary protocols...
  7. pmc Impact on survival and toxicity by duration of weight extremes during treatment for pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group
    Etan Orgel
    Etan Orgel, Jonathan Jaques Children s Cancer Center, Miller Children s Hospital, Long Beach Etan Orgel, Paul S Gaynon, and David R Freyer, Keck School of Medicine, University of Southern California Etan Orgel, Richard Sposto, Jemily Malvar, Paul S Gaynon, and David R Freyer, Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles Richard Sposto, University of Southern California, Los Angeles, CA Nita L Seibel, Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD and Elena Ladas, Center for Comprehensive Wellness, Columbia University, New York, NY
    J Clin Oncol 32:1331-7. 2014
    ..Inasmuch as weight varies substantially over treatment, we hypothesized its impact on EFS is instead determined by cumulative time spent at an extreme weight during therapy and on TRT by weight at the time of toxicity...
  8. pmc Low Enrollment of Adolescents and Young Adults Onto Cancer Trials: Insights From the Community Clinical Oncology Program
    Michael E Roth
    Albert Einstein College of Medicine, Bronx, NY National Cancer Institute, Bethesda, MD Helen DeVos Children s Hospital at Spectrum Health, Grand Rapids, MI University of Texas Health Science Center at San Antonio, San Antonio, TX University of California, Davis and University of Southern California, Los Angeles, CA
    J Oncol Pract 12:e388-95. 2016
    ..For these reasons, we hypothesized that CCOP sites enrolled proportionately more AYAs than non-CCOP sites onto Children's Oncology Group (COG) trials...
  9. doi request reprint Reconsidering Physical Activity Restrictions for Mononephric Survivors of Childhood Cancer: A Report From the Children's Oncology Group
    Maki Okada
    Miller Children s and Women s Hospital, Long Beach, CA, USA
    J Pediatr Oncol Nurs 33:306-13. 2016
    ..This has important implications for this and similar populations who may now undertake individual and organized sports without undue regard for their mononephric status. ..
  10. pmc Limitations of body mass index to assess body composition due to sarcopenic obesity during leukemia therapy
    Etan Orgel
    a Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles, Los Angeles, CA, USA
    Leuk Lymphoma . 2016
    ..Studies evaluating obesity in leukemia should consider using direct measures of body composition...
  11. pmc Comparative Toxicity by Sex Among Children Treated for Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group
    Kathleen A Meeske
    Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles, Los Angeles, California
    Pediatr Blood Cancer 62:2140-9. 2015
    ..The purpose of this study was to determine whether male and female patients differ with regard to acute treatment-related toxicities...
  12. doi request reprint Obesity is associated with residual leukemia following induction therapy for childhood B-precursor acute lymphoblastic leukemia
    Etan Orgel
    Children s Center for Cancer and Blood Disease, Children s Hospital Los Angeles, Los Angeles, CA Jonathan Jaques Children s Cancer Center, Miller Children s Hospital Long Beach, Long Beach, CA University of Southern California, Los Angeles, CA
    Blood 124:3932-8. 2014
    ..19 to 5.54; P = .016). Obesity and overweight were associated with poorer EFS irrespective of end-induction MRD (P = .012). Obese children with newly diagnosed BP-ALL are at increased risk for positive end-induction MRD and poorer EFS. ..
  13. doi request reprint Association of projected transfusional iron burden with treatment intensity in childhood cancer survivors
    Kathleen S Ruccione
    LIFE Cancer Survivorship and Transition Program, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Pediatr Blood Cancer 59:697-702. 2012
    ..The purpose of this study was to determine whether treatment intensity is predictive of projected iron burden resulting from PRBC transfusions among survivors of several forms of childhood cancer...
  14. doi request reprint Correlation of clinical and dosimetric factors with adverse pulmonary outcomes in children after lung irradiation
    Rajkumar Venkatramani
    Division of Hematology Oncology, Children s Hospital Los Angeles, Los Angeles, California, USA
    Int J Radiat Oncol Biol Phys 86:942-8. 2013
    ..To identify the incidence and the risk factors for pulmonary toxicity in children treated for cancer with contemporary lung irradiation...
  15. doi request reprint Exercise recommendations for childhood cancer survivors exposed to cardiotoxic therapies: an institutional clinical practice initiative
    Maki Okada
    Children s Hospital Los Angeles, CA 90027, USA
    J Pediatr Oncol Nurs 29:246-52. 2012
    ....
  16. doi request reprint Hearing loss among survivors of childhood brain tumors treated with an irradiation-sparing approach
    Etan Orgel
    Children s Center for Cancer and Blood Diseases, Children s Hospital, Los Angeles, CA, USA
    Pediatr Blood Cancer 58:953-8. 2012
    ..The purpose of this study was to determine the prevalence and severity of ototoxicity associated with Head Start and similar irradiation-sparing regimens...
  17. ncbi request reprint Development of a Culturally Competent Service to Improve Academic Functioning for Latino Survivors of Acute Lymphoblastic Leukemia: Methodological Considerations
    Laura Bava
    Children s Hospital Los Angeles, Los Angeles, CA, USA
    J Pediatr Oncol Nurs . 2016
    ..This report describes methodological considerations and practice implications relevant to the design and implementation of similar culturally competent services for Latino pediatric cancer survivors...
  18. doi request reprint Institutional adherence to cardiovascular risk factor screening guidelines for young survivors of acute lymphoblastic leukemia
    Maria H Lin
    Center for Endocrinology, Diabetes and Metabolism Diabetes and Obesity Program LIFE Cancer Survivorship and Transition Program Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles Keck School of Medicine, University of Southern California, Los Angeles, CA
    J Pediatr Hematol Oncol 37:e253-7. 2015
    ..CVRF screening practices met COG but not the more stringent AAP recommendations, particularly in areas of dyslipidemia and diabetes screening. Implications of our findings are discussed. ..
  19. pmc Carnitine and cardiac dysfunction in childhood cancer survivors treated with anthracyclines
    Saro H Armenian
    Authors Affiliations Division of Outcomes Research, Department of Population Sciences, Department of Cardiology, City of Hope, Duarte Divisions of Hematology, Oncology, and Blood and Marrow Transplantation and Cardiology, Children s Hospital Los Angeles Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California and Division of Pediatric Cardiology, Department of Pediatrics and Communicable Diseases, C S Mott Children s Hospital, University of Michigan, Ann Arbor, Michigan
    Cancer Epidemiol Biomarkers Prev 23:1109-14. 2014
    ..Cancer Epidemiol Biomarkers Prev; 23(6); 1109-14. ©2014 AACR. ..