B L Foster
Affiliation: University of Washington
- The progressive ankylosis protein regulates cementum apposition and extracellular matrix compositionB L Foster
Department of Periodontics, University of Washington School of Dentistry, Seattle, Wash 98195, USA
Cells Tissues Organs 194:382-405. 2011..Studies here aimed to define the role of ANK in root and cementum by analyzing tooth development in Ank knock-out (KO) mice versus wild type...
- Regulation of cementoblast gene expression by inorganic phosphate in vitroB L Foster
Department of Periodontics, School of Dentistry, University of Washington, Seattle, WA, USA
Calcif Tissue Int 78:103-12. 2006..During formation, phosphate and pyrophosphate may be important regulators of cementoblast functions including maturation and regulation of matrix mineralization...
- Defining the roots of cementum formationT Popowics
Department of Oral Biology, University of Washington School of Dentistry, Seattle, Wash 98195, USA
Cells Tissues Organs 181:248-57. 2005..e. follicle cells, periodontal cells, and cementoblasts) and offer new directions to consider for clinical repair of periodontal defects...
- Structure and mechanical properties of Ank/Ank mutant mouse dental tissues--an animal model for studying periodontal regenerationH Fong
Materials Science and Engineering, University of Washington, Seattle, WA, USA
Arch Oral Biol 54:570-6. 2009..In conclusion, these data suggest that this animal model can be utilized for studies focused on defining mechanisms to promote cementum formation without loss of mechanical integrity...
- Ablation of systemic phosphate-regulating gene fibroblast growth factor 23 (Fgf23) compromises the dentoalveolar complexE Y Chu
Department of Periodontics, School of Dentistry, University of Washington, Seattle, Washington, USA
Anat Rec (Hoboken) 293:1214-26. 2010..Based on these results, we propose that FGF23 and (P(i)) homeostasis play a significant role in maintenance of the dentoalveolar complex...
- Aberrant cementum phenotype associated with the hypophosphatemic hyp mouseH Fong
Department of Materials Science and Engineering, University of Washington, Seattle, WA, USA
J Periodontol 80:1348-54. 2009..Here, we report a developmental study of tooth root formation in Hyp mouse molars, focusing on dentin and cementum...
- Wnt/β-catenin pathway regulates bone morphogenetic protein (BMP2)-mediated differentiation of dental follicle cellsK G Silvério
Institute for Stem Cells and Regenerative Medicine, University of Washington, School of Medicine, Seattle, WA, USA
J Periodontal Res 47:309-19. 2012....
- Cementum: a phosphate-sensitive tissueF H Nociti
Department of Periodontics Prevention Geriatrics, School of Dentistry, Rm 3310M Dental, University of Michigan, 1011 N University Avenue, Ann Arbor, MI 48109 1078, USA
J Dent Res 81:817-21. 2002..This information may prove valuable in attempts to design successful therapies for regenerating periodontal tissues...
- Phosphate regulates osteopontin gene transcriptionS Fatherazi
Department of Oral Biology, University of Washington, Seattle, WA 98195 7132, USA
J Dent Res 88:39-44. 2009..The results presented support a model demonstrating that inorganic phosphate regulates OPN gene transcription in cementoblasts through a pathway that requires a functional GR...
- Extracellular phosphate alters cementoblast gene expressionR B Rutherford
Department of Oral Biology, School of Dentistry, University of Washington, Box 357132, Seattle, WA 98195 7132, USA
J Dent Res 85:505-9. 2006..Analyses of significant hybridization signals indicated that 5 mM extracellular phosphate alters the expression of genes comprising several gene ontology (GO) groups, including transcription factor activity and Wnt signaling...
- Full Spectrum of Postnatal Tooth Phenotypes in a Novel Irf6 Cleft Lip ModelE Y Chu
Department of Oral Health Sciences, University of Washington, Seattle, WA, USA Center for Developmental Biology and Regenerative Medicine, Seattle Children s Research Institute, Seattle, WA, USA National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA
J Dent Res 95:1265-73. 2016..This data reinforce the notion that various isolated tooth defects could be considered part of the CLP spectrum in relatives of an affected individual. ..
- Regulation of cementoblast function by P. gingivalis lipopolysaccharide via TLR2E Nemoto
Department of Periodontics, School of Dentistry, University of Washington, D322 Health Science Center Box 356365, Seattle, WA 98195 6365, USA
J Dent Res 85:733-8. 2006..These results suggest that cementoblasts participate in the recruitment of osteoclastic precursor cells by up-regulation of chemokines/cytokines...
- Regenerating the periodontium: is there a magic formula?B L Foster
Department of Periodontics, School of Dentistry, University of Washington, Seattle, 98195, USA
Orthod Craniofac Res 8:285-91. 2005..Critical to improving the predictability of regenerative therapies is targeting studies toward enhancing our understanding of the cellular and molecular events required to restore periodontal tissues...
- Cementoblast gene expression is regulated by Porphyromonas gingivalis lipopolysaccharide partially via toll-like receptor-4/MD-2F H Nociti
Department of Prosthodontics Periodontics, Division of Periodontics, School of Dentistry at Piracicaba, University of Campinas, Brazil
J Dent Res 83:602-7. 2004..g., RANKL/OPG), thereby potentially affecting the inflammation-associated resorption of mineralized tissues...