## Detail Information

### Publications

- Self-designing clinical trialsL D Fisher

Department of Biostatistics, University of Washington, Seattle 98195 7232, USA*Stat Med*17:1551-62. 1998.... - Advances in clinical trials in the twentieth centuryL D Fisher

Department of Biostatistics, University of Washington, Seattle 98195 7232, USA*Annu Rev Public Health*20:109-24. 1999..Recent methodology has also been concerned with the appropriateness of using surrogate endpoints. A current area of debate is the appropriateness of using Bayesian statistical methods in this context... - Time-dependent covariates in the Cox proportional-hazards regression modelL D Fisher

Department of Biostatistics, University of Washington, Seattle 98195 7232, USA*Annu Rev Public Health*20:145-57. 1999..The estimated probability of an event over time is not related to the hazard function in the usual fashion. An appendix summarizes the mathematics of time-dependent covariates...