Jonathan L Finlay

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi request reprint Progress in the treatment of childhood brain tumors: no room for complacency
    Jonathan L Finlay
    Department of Hematology Oncology, Children s Hospital, Los Angeles, California 90027, USA
    Pediatr Hematol Oncol 24:79-84. 2007
  2. pmc Myeloablative chemotherapy with autologous bone marrow rescue in children and adolescents with recurrent malignant astrocytoma: outcome compared with conventional chemotherapy: a report from the Children's Oncology Group
    Jonathan L Finlay
    The Children s Center for Cancer and Blood Diseases, Department of Pediatrics, Children s Hospital, Los Angeles, California 90027, USA
    Pediatr Blood Cancer 51:806-11. 2008
  3. ncbi request reprint The treatment of high grade gliomas and diffuse intrinsic pontine tumors of childhood and adolescence: a historical - and futuristic - perspective
    Jonathan L Finlay
    The Neural Tumors Program, Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, USA
    J Neurooncol 75:253-66. 2005
  4. ncbi request reprint Burkitt's and Burkitt-like lymphoma in children and adolescents: a review of the Children's Cancer Group experience
    Mitchell S Cairo
    Department of Pediatrics, Children s Hospital New York, Columbia University, New York, NY, USA
    Br J Haematol 120:660-70. 2003
  5. doi request reprint Disseminated lymphoblastic lymphoma in children and adolescents: results of the COG A5971 trial: a report from the Children's Oncology Group
    Amanda M Termuhlen
    Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Br J Haematol 162:792-801. 2013
  6. doi request reprint High-dose chemotherapy and autologous hematopoietic progenitor cell rescue in children with recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors: the impact of prior radiotherapy on outcome
    Anna M Butturini
    Division of Hematology Oncology, Childrens Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Cancer 115:2956-63. 2009
  7. ncbi request reprint Thiotepa-based high-dose chemotherapy with autologous stem-cell rescue in patients with recurrent or progressive CNS germ cell tumors
    Shakeel Modak
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Clin Oncol 22:1934-43. 2004
  8. pmc Elevated citrate in pediatric astrocytomas with malignant progression
    Stefan Bluml
    Department of Radiology, Children s Hospital Los Angeles, MS 81, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA
    Neuro Oncol 13:1107-17. 2011
  9. doi request reprint Treatment of primary CNS germinomatous germ cell tumors with chemotherapy prior to reduced dose whole ventricular and local boost irradiation
    Soumen Khatua
    Neural Tumors Program, Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, California, USA
    Pediatr Blood Cancer 55:42-6. 2010
  10. doi request reprint Outcome of children less than three years old at diagnosis with non-metastatic medulloblastoma treated with chemotherapy on the "Head Start" I and II protocols
    Girish Dhall
    Childrens Hospital Los Angeles, Los Angeles, California, USA
    Pediatr Blood Cancer 50:1169-75. 2008

Detail Information

Publications60

  1. ncbi request reprint Progress in the treatment of childhood brain tumors: no room for complacency
    Jonathan L Finlay
    Department of Hematology Oncology, Children s Hospital, Los Angeles, California 90027, USA
    Pediatr Hematol Oncol 24:79-84. 2007
  2. pmc Myeloablative chemotherapy with autologous bone marrow rescue in children and adolescents with recurrent malignant astrocytoma: outcome compared with conventional chemotherapy: a report from the Children's Oncology Group
    Jonathan L Finlay
    The Children s Center for Cancer and Blood Diseases, Department of Pediatrics, Children s Hospital, Los Angeles, California 90027, USA
    Pediatr Blood Cancer 51:806-11. 2008
    ..Children and adolescents with malignant astrocytomas recurring after initial treatment have a dismal prognosis, with only rare patients surviving 1-year beyond recurrence. The purpose of this study was to attempt to improve their survival...
  3. ncbi request reprint The treatment of high grade gliomas and diffuse intrinsic pontine tumors of childhood and adolescence: a historical - and futuristic - perspective
    Jonathan L Finlay
    The Neural Tumors Program, Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, USA
    J Neurooncol 75:253-66. 2005
    ..High dose chemotherapy with autologous stem cell rescue in selected patients with minimal residual disease, angiogenesis inhibitors, radiosensitizers and other biological modifiers are being currently investigated in phase I/II trials...
  4. ncbi request reprint Burkitt's and Burkitt-like lymphoma in children and adolescents: a review of the Children's Cancer Group experience
    Mitchell S Cairo
    Department of Pediatrics, Children s Hospital New York, Columbia University, New York, NY, USA
    Br J Haematol 120:660-70. 2003
    ..001). In summary, the outcome for childhood Burkitt's and Burkitt-like lymphoma has recently improved with the use of short and intensive B-cell non-Hodgkin's lymphoma-directed therapy...
  5. doi request reprint Disseminated lymphoblastic lymphoma in children and adolescents: results of the COG A5971 trial: a report from the Children's Oncology Group
    Amanda M Termuhlen
    Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Br J Haematol 162:792-801. 2013
    ..CNS positive patients (n = 12) did poorly [5-year EFS of 63% (95% CI 29-85%)]. For CNS-negative patients, there was no difference in outcome based on CNS prophylaxis (IT-MTX versus HD-MTX) or with intensification...
  6. doi request reprint High-dose chemotherapy and autologous hematopoietic progenitor cell rescue in children with recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors: the impact of prior radiotherapy on outcome
    Anna M Butturini
    Division of Hematology Oncology, Childrens Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Cancer 115:2956-63. 2009
    ....
  7. ncbi request reprint Thiotepa-based high-dose chemotherapy with autologous stem-cell rescue in patients with recurrent or progressive CNS germ cell tumors
    Shakeel Modak
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Clin Oncol 22:1934-43. 2004
    ..To evaluate the efficacy and toxicity of high-dose chemotherapy (HDC) followed by autologous stem-cell rescue (ASCR) in patients with relapsed or progressive CNS germ cell tumors (GCTs)...
  8. pmc Elevated citrate in pediatric astrocytomas with malignant progression
    Stefan Bluml
    Department of Radiology, Children s Hospital Los Angeles, MS 81, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA
    Neuro Oncol 13:1107-17. 2011
    ..Citrate was not specific for poor outcome because it was not detectable in all high-grade astrocytomas. In high-grade astrocytoma, tumors with prominent citrate may constitute a metabolic subclass...
  9. doi request reprint Treatment of primary CNS germinomatous germ cell tumors with chemotherapy prior to reduced dose whole ventricular and local boost irradiation
    Soumen Khatua
    Neural Tumors Program, Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, California, USA
    Pediatr Blood Cancer 55:42-6. 2010
    ..The purpose of this study was to evaluate a reduced irradiation dose strategy for newly diagnosed primary central nervous system (CNS) germinomas...
  10. doi request reprint Outcome of children less than three years old at diagnosis with non-metastatic medulloblastoma treated with chemotherapy on the "Head Start" I and II protocols
    Girish Dhall
    Childrens Hospital Los Angeles, Los Angeles, California, USA
    Pediatr Blood Cancer 50:1169-75. 2008
    ..To determine the survival of infants and young children with non-metastatic medulloblastoma using intensive myeloablative chemotherapy and autologous hematopoietic progenitor cell rescue (AuHCR)...
  11. doi request reprint Trilateral retinoblastoma: potentially curable with intensive chemotherapy
    Ira J Dunkel
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Pediatr Blood Cancer 54:384-7. 2010
    ..We describe a series of 13 patients treated with intensive chemotherapy, defined as the intention to include high-dose chemotherapy with autologous hematopoietic stem cell rescue...
  12. pmc Molecular subgroups of medulloblastoma identification using noninvasive magnetic resonance spectroscopy
    Stefan Bluml
    Children s Hospital Los Angeles and the Saban Research Institute, Los Angeles, California S B, A S M, R S, R J K, N J R, M V, L T H, S M, A E E, F H G, A R J, M D K, G D, M D N, S A Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California S B, M D N Rudi Schulte Research Institute, Santa Barbara, California S B, M D N Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California R S Department of Pediatrics, Nationwide Children s Hospital, Columbus, Ohio J L F Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California A E E, F H G, Tokyo
    Neuro Oncol 18:126-31. 2016
    ..In this study, we investigated the hypothesis that metabolite concentrations measured by MRS would differ between molecular subgroups of medulloblastoma and allow accurate subgroup determination...
  13. ncbi request reprint Anaplastic mixed gliomas and anaplastic oligodendroglioma in children: results from the CCG 945 experience
    Douglas J Hyder
    Department of Pediatrics, Children s Hospital at Dartmouth, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    J Neurooncol 83:1-8. 2007
    ..To review interpathologist diagnosis variability and survival of children treated for either anaplastic mixed glioma (AMG) or anaplastic oligodendroglioma (AO) with surgery, irradiation and chemotherapy...
  14. doi request reprint Diffusion Tensor Imaging and Neurobehavioral Outcome in Children With Brain Tumors Treated With Chemotherapy
    MARY BARON NELSON
    Children s Hospital Los Angeles, Los Angeles, CA, USA UCLA School of Nursing, Los Angeles, CA, USA
    J Pediatr Oncol Nurs 33:119-28. 2016
    ..Our objective was to relate brain tissue changes to neurocognitive and QOL effects after systemic myeloablative chemotherapy with autologous hematopoietic progenitor cell rescue in CBTS...
  15. ncbi request reprint A phase II trial of carboplatin for intraocular retinoblastoma
    Ira J Dunkel
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Pediatr Blood Cancer 49:643-8. 2007
    ....
  16. doi request reprint Pineal region tumors in children
    Girish Dhall
    Division of Pediatric Hematology Oncology at Children s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California 90027, USA
    Curr Opin Neurol 23:576-82. 2010
    ..Pineal tumors are rare in children, with pineoblastoma and germ cell tumors (GCTs) being the most common. Here we discuss recent advances in treatment and controversies in the management of these tumors...
  17. doi request reprint Neuropsychological functioning of children treated with intensive chemotherapy followed by myeloablative consolidation chemotherapy and autologous hematopoietic cell rescue for newly diagnosed CNS tumors: an analysis of the Head Start II survivors
    Stephen A Sands
    Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Pediatr Blood Cancer 54:429-36. 2010
    ..To evaluate the neuropsychological late effects amongst survivors treated on the Head Start II protocol between 1997 and 2003...
  18. pmc False-positive magnetic resonance imaging findings in follow-up of pediatric patients with tumors of the central nervous system
    Satiro Nakamura De Oliveira
    Mattel Children s Hospital, University of California Los Angeles, Los Angeles, CA, USA
    SAGE Open Med Case Rep 4:2050313X16666232. 2016
    ..A step-wise approach for such challenging cases is presented in this article. ..
  19. doi request reprint Choroid plexus tumors; management, outcome, and association with the Li-Fraumeni syndrome: the Children's Hospital Los Angeles (CHLA) experience, 1991-2010
    Alexa E Gozali
    Children s Center for Cancer and Blood Diseases, Children s Hospital, Los Angeles, CA, USA
    Pediatr Blood Cancer 58:905-9. 2012
    ..We have investigated the clinical features and overall survival of all CPT patients treated at Children's Hospital Los Angeles (CHLA) over a 20-year period, with particular attention to the association of CPT with LFS...
  20. doi request reprint Regression of primary central nervous system germinoma after dexamethasone administration: a case report
    Stephanie J Si
    Neural Tumors Program, Children s Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, California, USA
    Pediatr Hematol Oncol 27:237-43. 2010
    ..Perioperative corticosteroid administration in patients with CNS germinoma may obfuscate the increase in response demonstrated with various chemotherapy regimens or with irradiation in CNS germinomas...
  21. doi request reprint Recurrent pure CNS germinoma with markedly elevated serum and cerebrospinal fluid human chorionic gonadotropin-beta (HCGβ)
    Soumen Khatua
    Neural Tumors Program, Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, CA, USA
    Pediatr Blood Cancer 56:863-4. 2011
    ..This case illustrates the need to re-evaluate the assumption that pathologically pure germinomas may be associated with high levels of HCGβ which are unrelated to nongerminomatous germ cell tumor (NGGCT)/choriocarcinomatous elements...
  22. ncbi request reprint Pathologist interobserver variability of histologic features in childhood brain tumors: results from the CCG-945 study
    Floyd H Gilles
    Neuropathology, Childrens Hospital, Los Angeles, CA 90027, USA
    Pediatr Dev Pathol 11:108-17. 2008
    ..Agreement and strict adherence to improved nonsubjective diagnostic criteria would improve histologic feature reliability and, consequently, their usefulness in studies...
  23. ncbi request reprint Recurrent central nervous system medulloepithelioma: response and outcome following marrow-ablative chemotherapy with stem cell rescue
    Lindsey S Norris
    Department of Pediatrics, New York University School of Medicine, New York, NY, USA
    J Pediatr Hematol Oncol 27:264-6. 2005
    ....
  24. ncbi request reprint High-dose chemotherapy with autologous stem cell rescue for brain tumors
    Ira J Dunkel
    Memorial Sloan Kettering Cancer Center, Department of Pediatrics, Box 185, 1275 York Avenue, New York, NY 10021, USA
    Crit Rev Oncol Hematol 41:197-204. 2002
    ..The role of this treatment strategy for other chemotherapy-sensitive tumors such as oligodendrogliomas and central nervous system germ cell tumors has yet to be determined...
  25. pmc Metabolism of diffuse intrinsic brainstem gliomas in children
    Ashok Panigrahy
    Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Department of Radiology, Los Angeles, CA 90027, USA
    Neuro Oncol 10:32-44. 2008
    ..Subsequent metabolic changes that have been associated with malignant degeneration preceded clinical deterioration. MRS provides early surrogate markers for disease progression...
  26. doi request reprint Feasibility of dasatinib in children and adolescents with new or recurrent central nervous system germinoma
    Diana S Osorio
    The Neuro Oncology Program, Children s Center for Cancer and Blood Diseases, Children s Hospital Los Angeles, Los Angeles, California, USA
    Pediatr Blood Cancer 60:E100-2. 2013
    ..The daily doses administered were 100-170 mg/m(2) with mostly grade 1-2 toxicities. Dasatinib may play a role in future treatment strategies for CNS GCT...
  27. doi request reprint Supratentorial ependymoma in children: to observe or to treat following gross total resection?
    Rajkumar Venkatramani
    Division of Hematology Oncology, Children s Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA
    Pediatr Blood Cancer 58:380-3. 2012
    ..The role of radiation therapy in completely resected supratentorial ependymoma has been questioned over the past two decades...
  28. doi request reprint Primary mixed glioneuronal tumor of the central nervous system in a patient with noonan syndrome: a case report and review of the literature
    Courtney B Sherman
    Children s Center for Cancer and Blood Diseases, Los Angeles, CA, USA
    J Pediatr Hematol Oncol 31:61-4. 2009
    ....
  29. ncbi request reprint Brainstem primitive neuroectodermal tumors (bstPNET): results of treatment with intensive induction chemotherapy followed by consolidative chemotherapy with autologous hematopoietic cell rescue
    Jason R Fangusaro
    The Children s Hospital Los Angeles, New York University Medical Center, Memorial Sloan Kettering Cancer Center, and Schneider Children s Hospital, USA
    Pediatr Blood Cancer 50:715-7. 2008
    ..Two patients survive at least 32 months with stable disease. This approach provides an alternative for young patients with bstPNET who in prior reports have had a uniformly fatal prognosis...
  30. doi request reprint Tumor-associated macrophages in SHH subgroup of medulloblastomas
    Ashley S Margol
    Children s Hospital Los Angeles and the Saban Research Institute, Los Angeles, California Department of Pediatrics, Keck School of Medicine of University of Southern California, Los Angeles, California
    Clin Cancer Res 21:1457-65. 2015
    ..In this study, we investigated the hypothesis that expression of genes related to tumor-associated macrophages (TAM) correlates with the medulloblastoma molecular subgroups and contributes to a diagnostic signature...
  31. doi request reprint Outcome of newly diagnosed children and adolescents with localized lymphoblastic lymphoma treated on Children's Oncology Group trial A5971: a report from the Children's Oncology Group
    Amanda M Termuhlen
    Department of Pediatrics, Keck School of Medicine, University of Southern California 701 E 28th St, Suite 202, Long Beach, CA 90806, USA
    Pediatr Blood Cancer 59:1229-33. 2012
    ..We report the 5-year event-free survival (EFS) and overall survival (OS) for children and adolescents with localized LL treated on a uniform regimen based on Children's Cancer Group (CCG) leukemia therapy (COG A5971)...
  32. doi request reprint The role of chemotherapy in pediatric clival chordomas
    Girish Dhall
    Neural Tumors Program, The Division of Pediatric Hematology Oncology and Department of Pathology at Childrens Hospital Los Angeles, Los Angeles, CA, USA
    J Neurooncol 103:657-62. 2011
    ..Chemotherapy with ifosfamide and etoposide may have a role in the treatment of pediatric clival chordomas when used alone or in combination with irradiation...
  33. ncbi request reprint Analysis of outcome for patients with mass lesions of the central nervous system due to Langerhans cell histiocytosis treated with 2-chlorodeoxyadenosine
    Girish Dhall
    Children s Hospital Los Angeles, Los Angeles, California, USA
    Pediatr Blood Cancer 50:72-9. 2008
    ..To assess the activity and tolerability of 2-chlorodeoxyadenosine (2-CDA) in treating mass lesions of the central nervous system (CNS) due to Langerhans cell histiocytosis (LCH)...
  34. doi request reprint Aggressive variant of a papillary glioneuronal tumor. Report of 2 cases
    Ramin J Javahery
    Division of Neurosurgery, Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Neurosurg Pediatr 3:46-52. 2009
    ..The first patient had dissemination of her tumor and the second had local spreading. Therefore, the authors conclude that papillary glioneuronal tumors do not always behave in a strictly benign fashion...
  35. pmc Disseminated Medulloblastoma in a Child with Germline BRCA2 6174delT Mutation and without Fanconi Anemia
    Jingying Xu
    Division of Hematology Oncology, Department of Pediatrics, Children s Hospital Los Angeles, Los Angeles, CA, USA
    Front Oncol 5:191. 2015
    ....
  36. doi request reprint Pilot study assessing a seven-day continuous intrathecal topotecan infusion for recurrent or progressive leptomeningeal metastatic cancer
    Hung C Tran
    Division of Hematology Oncology, Children s Hospital Los Angeles, Los Angeles, CA, USA Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    J Oncol Pharm Pract 20:229-32. 2014
    ..To determine the feasibility and toxicity profile of topotecan administered as a seven-day continuous intrathecal infusion for patients with leptomeningeal metastasis secondary to recurrent or progressive central nervous system cancer...
  37. ncbi request reprint Temozolomide is active in childhood, progressive, unresectable, low-grade gliomas
    Dennis J Kuo
    Department of Pediatrics, New York University, New York, USA
    J Pediatr Hematol Oncol 25:372-8. 2003
    ..To assess the activity and tolerability of temozolomide in children with progressive low-grade gliomas (LGGs)...
  38. ncbi request reprint State of the art chemotherapeutic management of pediatric brain tumors
    Melissa J Siegel
    Childrens Hospital Los Angeles, The Neural Tumos Program, Childrens Center for Cancer and Blood Diseases, Los Angeles, California, USA
    Expert Rev Neurother 6:765-79. 2006
    ..Similarly, these agents will need to be examined in combination with cytotoxic chemotherapy. Finally, the future direction of pediatric neuro-oncology and the focus of the field as it battles pediatric brain tumors is discussed...
  39. ncbi request reprint Childhood and adolescent large-cell lymphoma (LCL): a review of the Children's Cancer Group experience
    Mitchell S Cairo
    Department of Pediatrics, Columbia University, New York, New York, USA
    Am J Hematol 72:53-63. 2003
    ..Large numbers of patients treated with shorter and intense therapy are required to confirm these preliminary observations...
  40. ncbi request reprint Gastrointestinal involvement in disseminated Langerhans cell histiocytosis (LCH) with durable complete response to 2-chlorodeoxyadenosine and high-dose cytarabine
    Sung W Choi
    Department of Pediatrics, New York University Medical Center, New York, New York, USA
    J Pediatr Hematol Oncol 25:503-6. 2003
    ..Twenty-seven months since the last course of chemotherapy, the patient continues to thrive free of disease. Treatment with 2-chlorodeoxyadenosine and cytarabine should be considered for further study in patients with poor-prognosis LCH...
  41. pmc Structural brain alterations in children an average of 5 years after surgery and chemotherapy for brain tumors
    Mary Baron Nelson
    Children s Hospital Los Angeles, 4650 Sunset Blvd MS 54, Los Angeles, CA, 90027, USA
    J Neurooncol 119:317-26. 2014
    ..4 years earlier show alterations in white and gray matter in multiple brain areas distant from the tumor site, raising the possibility for long-term consequences of the tumor or treatment...
  42. ncbi request reprint Expression of p53 and prognosis in children with malignant gliomas
    Ian F Pollack
    Department of Neurosurgery, University of Pittsburgh Medical Center and Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    N Engl J Med 346:420-7. 2002
    ..We investigated whether mutations in the TP53 gene or the degree of expression of p53 protein in high-grade gliomas is associated with progression-free survival in children with these tumors...
  43. ncbi request reprint Combined modality therapy for poorly differentiated gliomas of the posterior fossa in children: a Children's Cancer Group report
    Salvatore J Bertolone
    University of Louisville School of Medicine, Division of Pediatric Hematology Oncology Bone Marrow Transplantation, Louisville, KY, USA
    J Neurooncol 63:49-54. 2003
    ..To study the effectiveness of combined chemotherapy and radiotherapy for children with high-grade astrocytomas of the posterior fossa...
  44. ncbi request reprint Diabetes insipidus and Langerhans cell histiocytosis: a case report of reversibility with 2-chlorodeoxyadenosine
    Fabio Ottaviano
    The Neuro oncology Program of the New York University Cancer Institute and the Department of Pediatrics, New York University School of Medicine, 317 East 34th Street, 10th Floor, New York, NY 10016, U S A
    J Pediatr Hematol Oncol 25:575-7. 2003
    ..The authors report the successful reversal of DI in a 3-year-old child with established LCH using 2-CDA...
  45. ncbi request reprint Outcome of children with centrally reviewed low-grade gliomas treated with chemotherapy with or without radiotherapy on Children's Cancer Group high-grade glioma study CCG-945
    Maryam Fouladi
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Cancer 98:1243-52. 2003
    ....
  46. ncbi request reprint High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma
    Lauren E Abrey
    Department of Neurology, Memorial Sloan Kettering Cancer Center, New York 10021, USA
    J Neurooncol 65:127-34. 2003
    ....
  47. ncbi request reprint High-dose chemotherapy with autologous stem-cell rescue in the treatment of patients with recurrent non-cerebellar primitive neuroectodermal tumors
    Alberto Broniscer
    Children s Cancer Group New York University Medical Center, New York, NY, USA
    Pediatr Blood Cancer 42:261-7. 2004
    ..XSWe tested the efficacy of high-dose chemotherapy (HDC) followed by autologous stem-cell rescue (ASCR) in this setting...
  48. ncbi request reprint Multiagent chemotherapy and deferred radiotherapy in infants with malignant brain tumors: a report from the Children's Cancer Group
    J Russell Geyer
    Children s Hospital and Regional Medical Center, Department of Pediatric Hematology Oncology, Seattle, WA 98105, USA
    J Clin Oncol 23:7621-31. 2005
    ....
  49. pmc High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma: long-term follow-up
    Lauren E Abrey
    Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Neuro Oncol 8:183-8. 2006
    ..This treatment strategy affords long-term disease control to a subset of patients with newly diagnosed anaplastic oligodendroglioma without evidence of delayed neurotoxicity or myelodysplasia...
  50. ncbi request reprint Feasibility and response to induction chemotherapy intensified with high-dose methotrexate for young children with newly diagnosed high-risk disseminated medulloblastoma
    Susan N Chi
    Division of Pediatric Oncology, New York University Medical Center, New York, NY, USA
    J Clin Oncol 22:4881-7. 2004
    ..To evaluate the feasibility of and response rate to an intensified induction chemotherapy regimen for young children with newly diagnosed high-risk or disseminated medulloblastomas...
  51. ncbi request reprint Intensive cisplatin and cyclophosphamide-based chemotherapy without radiotherapy for intracranial germinomas: failure of a primary chemotherapy approach
    Stewart J Kellie
    Oncology Unit, The Children s Hospital at Westmead, Sydney, NSW, Australia
    Pediatr Blood Cancer 43:126-33. 2004
    ..The primary objective of this study was to determine whether intensive cisplatin and cyclophosphamide-based combination chemotherapy, without radiotherapy, was effective in patients with CNS germinomas...
  52. ncbi request reprint Primary chemotherapy for intracranial nongerminomatous germ cell tumors: results of the second international CNS germ cell study group protocol
    Stewart J Kellie
    Oncology Unit, The Children s Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145, Australia
    J Clin Oncol 22:846-53. 2004
    ..The primary objective of this study was to determine whether intensive cisplatin and cyclophosphamide-based combination chemotherapy was effective in patients with intracranial NGGCT...
  53. ncbi request reprint Treatment of refractory neurosarcoidosis with cladribine
    Ravi K Tikoo
    N Engl J Med 350:1798-9. 2004
  54. ncbi request reprint Invariant natural killer T cells are preserved in patients with glioma and exhibit antitumor lytic activity following dendritic cell-mediated expansion
    Kavita M Dhodapkar
    Laboratory of Cellular Physiology and Immunology and Chris Browne Center for Immunology and Human Disease, Rockefeller University, New York, NY 10021, USA
    Int J Cancer 109:893-9. 2004
    ..These data suggest that targeting NKT cells may provide a novel strategy for immunotherapy of glioma...
  55. pmc The influence of central review on outcome associations in childhood malignant gliomas: results from the CCG-945 experience
    Ian F Pollack
    Department of Neurosurgery, University of Pittsburgh School of Medicine and the Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    Neuro Oncol 5:197-207. 2003
    ....
  56. ncbi request reprint Association between chromosome 1p and 19q loss and outcome in pediatric malignant gliomas: results from the CCG-945 cohort
    Ian F Pollack
    Department of Neurosurgery, University of Pittsburgh Medical Center and the Children s Hospital of Pittsburgh, Pittsburgh, PA, USA
    Pediatr Neurosurg 39:114-21. 2003
    ....
  57. ncbi request reprint Impact of proliferation index on outcome in childhood malignant gliomas: results in a multi-institutional cohort
    Ian F Pollack
    Departments of Neurosurgery, University of Pittsburgh Medical Center and the Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Neurosurgery 50:1238-44; discussion 1244-5. 2002
    ....
  58. ncbi request reprint Delayed surgical resection of central nervous system germ cell tumors
    Howard L Weiner
    Department of Neurosurgery, New York University Medical Center, New York Presbyterian Hospital, New York, New York 10016, USA
    Neurosurgery 50:727-33; discussion 733-4. 2002
    ....
  59. ncbi request reprint O6-methylguanine-DNA methyltransferase expression strongly correlates with outcome in childhood malignant gliomas: results from the CCG-945 Cohort
    Ian F Pollack
    Department of Neurosurgery, University of Pittsburgh Cancer Institute, University of Pittsburgh Medical Center and the Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    J Clin Oncol 24:3431-7. 2006
    ..Epigenetic silencing of MGMT has been associated with prolonged survival in adults with malignant gliomas, although the association between MGMT expression status and outcome in pediatric malignant gliomas has not been defined...
  60. ncbi request reprint Rarity of PTEN deletions and EGFR amplification in malignant gliomas of childhood: results from the Children's Cancer Group 945 cohort
    Ian F Pollack
    Departments of Neurosurgery, University of Pittsburgh Medical Center, Children s Hospital of Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 105:418-24. 2006
    ..To address this issue, we examined tumor samples from the Children's Cancer Group 945 study, a large randomized trial of treatment for childhood malignant gliomas...