Elissa S Epel

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Cell aging in relation to stress arousal and cardiovascular disease risk factors
    Elissa S Epel
    UCSF Department of Psychiatry, San Francisco, CA, USA
    Psychoneuroendocrinology 31:277-87. 2006
  2. doi request reprint Depression gets old fast: do stress and depression accelerate cell aging?
    Owen M Wolkowitz
    Department of Psychiatry, University of California School of Medicine, San Francisco, California, USA
    Depress Anxiety 27:327-38. 2010
  3. pmc PBMC telomerase activity, but not leukocyte telomere length, correlates with hippocampal volume in major depression
    Owen M Wolkowitz
    Department of Psychiatry, University of California San Francisco UCSF School of Medicine, San Francisco, CA, USA Electronic address
    Psychiatry Res 232:58-64. 2015
  4. pmc Stress appraisals and cellular aging: a key role for anticipatory threat in the relationship between psychological stress and telomere length
    Aoife O'Donovan
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Brain Behav Immun 26:573-9. 2012
  5. pmc Effects of a mindfulness-based intervention on mindful eating, sweets consumption, and fasting glucose levels in obese adults: data from the SHINE randomized controlled trial
    Ashley E Mason
    Osher Center for Integrative Medicine, University of California San Francisco UCSF, 1545 Divisadero Street, 4th Floor, San Francisco, CA, 94115, USA
    J Behav Med 39:201-13. 2016
  6. doi request reprint Association of dimensional psychological health measures with telomere length in male war veterans
    Francesco S Bersani
    Department of Psychiatry, University of California San Francisco, San Francisco, CA, USA Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy
    J Affect Disord 190:537-42. 2016
  7. doi request reprint Global arginine bioavailability, a marker of nitric oxide synthetic capacity, is decreased in PTSD and correlated with symptom severity and markers of inflammation
    Francesco Saverio Bersani
    Department of Psychiatry, University of California San Francisco, San Francisco, CA, United States Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy
    Brain Behav Immun 52:153-60. 2016
  8. pmc Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging
    Daniel Lindqvist
    Department of Clinical Sciences, Section for Psychiatry, Lund University, Lund, Sweden Department of Psychiatry, University of California San Francisco UCSF, School of Medicine, San Francisco, CA, USA
    Neurosci Biobehav Rev 55:333-64. 2015
  9. pmc Dynamics of telomerase activity in response to acute psychological stress
    Elissa S Epel
    Department of Psychiatry, University of California, San Francisco, 3333 Calif St, Suite 465, San Francisco, CA 94143, USA
    Brain Behav Immun 24:531-9. 2010
  10. pmc Accelerated telomere shortening in response to life stress
    Elissa S Epel
    Department of Psychiatry, University of California, 3333 California Street, Suite 465, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:17312-5. 2004

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Cell aging in relation to stress arousal and cardiovascular disease risk factors
    Elissa S Epel
    UCSF Department of Psychiatry, San Francisco, CA, USA
    Psychoneuroendocrinology 31:277-87. 2006
    ..These findings may implicate telomerase as a novel and important mediator of the effects of psychological stress on physical health and disease...
  2. doi request reprint Depression gets old fast: do stress and depression accelerate cell aging?
    Owen M Wolkowitz
    Department of Psychiatry, University of California School of Medicine, San Francisco, California, USA
    Depress Anxiety 27:327-38. 2010
    ....
  3. pmc PBMC telomerase activity, but not leukocyte telomere length, correlates with hippocampal volume in major depression
    Owen M Wolkowitz
    Department of Psychiatry, University of California San Francisco UCSF School of Medicine, San Francisco, CA, USA Electronic address
    Psychiatry Res 232:58-64. 2015
    ....
  4. pmc Stress appraisals and cellular aging: a key role for anticipatory threat in the relationship between psychological stress and telomere length
    Aoife O'Donovan
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Brain Behav Immun 26:573-9. 2012
    ..Exaggerated anticipatory threat appraisals may be a common and modifiable psychological mechanism of psychological stress effects on cellular aging...
  5. pmc Effects of a mindfulness-based intervention on mindful eating, sweets consumption, and fasting glucose levels in obese adults: data from the SHINE randomized controlled trial
    Ashley E Mason
    Osher Center for Integrative Medicine, University of California San Francisco UCSF, 1545 Divisadero Street, 4th Floor, San Francisco, CA, 94115, USA
    J Behav Med 39:201-13. 2016
    ..Increases in mindful eating may contribute to the effects of mindfulness-based weight loss interventions on eating of sweets and fasting glucose levels. ..
  6. doi request reprint Association of dimensional psychological health measures with telomere length in male war veterans
    Francesco S Bersani
    Department of Psychiatry, University of California San Francisco, San Francisco, CA, USA Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy
    J Affect Disord 190:537-42. 2016
    ..We explored the association between dimensional psychopathological measures and telomere length (TL) in granulocytes among veterans independent of psychiatric diagnosis...
  7. doi request reprint Global arginine bioavailability, a marker of nitric oxide synthetic capacity, is decreased in PTSD and correlated with symptom severity and markers of inflammation
    Francesco Saverio Bersani
    Department of Psychiatry, University of California San Francisco, San Francisco, CA, United States Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy
    Brain Behav Immun 52:153-60. 2016
    ....
  8. pmc Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging
    Daniel Lindqvist
    Department of Clinical Sciences, Section for Psychiatry, Lund University, Lund, Sweden Department of Psychiatry, University of California San Francisco UCSF, School of Medicine, San Francisco, CA, USA
    Neurosci Biobehav Rev 55:333-64. 2015
    ..A deeper understanding of cellular aging in psychiatric illnesses could lead to re-conceptualizing them as systemic illnesses with manifestations inside and outside the brain and could identify new treatment targets. ..
  9. pmc Dynamics of telomerase activity in response to acute psychological stress
    Elissa S Epel
    Department of Psychiatry, University of California, San Francisco, 3333 Calif St, Suite 465, San Francisco, CA 94143, USA
    Brain Behav Immun 24:531-9. 2010
    ....
  10. pmc Accelerated telomere shortening in response to life stress
    Elissa S Epel
    Department of Psychiatry, University of California, 3333 California Street, Suite 465, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:17312-5. 2004
    ..These findings have implications for understanding how, at the cellular level, stress may promote earlier onset of age-related diseases...
  11. pmc Effects of a mindfulness-based weight loss intervention in adults with obesity: A randomized clinical trial
    JENNIFER DAUBENMIER
    Osher Center for Integrative Medicine, University of California, San Francisco, California, USA
    Obesity (Silver Spring) 24:794-804. 2016
    ..To determine whether adding mindfulness-based eating and stress management practices to a diet-exercise program improves weight loss and metabolic syndrome components...
  12. ncbi request reprint The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men
    Elissa S Epel
    University of California, San Francisco, Department of Psychiatry, San Francisco, CA, 94143, USA
    Aging (Albany NY) 1:81-8. 2008
    ..0 (95% CI: 1.1 - 8.2). This is the first demonstration that rate of telomere length change (TLC) predicts mortality and thus may be a useful prognostic factor for longevity...
  13. pmc Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease
    Ramin Farzaneh-Far
    Division of Cardiology, Room 5G1, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA
    JAMA 303:250-7. 2010
    ..Increased dietary intake of marine omega-3 fatty acids is associated with prolonged survival in patients with coronary heart disease. However, the mechanisms underlying this protective effect are poorly understood...
  14. pmc The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men
    Elissa S Epel
    University of California, San Francisco, Department of Psychiatry, San Francisco, CA, 94143, USA
    Aging (Albany NY) 1:81-8. 2009
    ..0 (95% CI: 1.1 - 8.2). This is the first demonstration that rate of telomere length change (TLC) predicts mortality and thus may be a useful prognostic factor for longevity...
  15. ncbi request reprint Psychological and metabolic stress: a recipe for accelerated cellular aging?
    Elissa S Epel
    University of California, Department of Psychiatry, San Francisco, CA 94143, USA
    Hormones (Athens) 8:7-22. 2009
    ..Certain psychological temperaments at high risk of this stress cascade (mainly anxiety prone), gene-environment interactions, and potential interventions for interrupting the stress-aging cascade are discussed...
  16. pmc Anger is associated with increased IL-6 stress reactivity in women, but only among those low in social support
    Eli Puterman
    Department of Psychiatry, School of Medicine, University of California, San Francisco, CA, USA
    Int J Behav Med 21:936-45. 2014
    ..Affective states (anger, fear, and anxiety) predict interleukin-6 (IL-6) reactivity to acute stress; in turn, this reactivity predicts risk of cardiovascular disease progression...
  17. pmc Chronic stress elevates telomerase activity in rats
    Annaliese K Beery
    Robert Wood Johnson Health and Society Scholar at University of California at San Francisco, San Francisco, CA 04143, USA
    Biol Lett 8:1063-6. 2012
    ..This significant increase suggests a potential mechanism for resilience to stress-related replicative senescence...
  18. pmc Telomere shortening in formerly abused and never abused women
    Janice Humphreys
    Department of Family Health Care Nursing, School of Nursing, University of California, San Francisco, CA 94143, USA
    Biol Res Nurs 14:115-23. 2012
    ..Findings from this descriptive study suggest a link between IPV exposure, duration of IPV-related stress, and telomere length molecular mechanisms that regulate cellular aging...
  19. doi request reprint Positive affect uniquely predicts lower risk of mortality in people with diabetes
    Judith Tedlie Moskowitz
    Osher Center for Integrative Medicine, University of California, San Francisco, CA 94115, USA
    Health Psychol 27:S73-82. 2008
    ..To determine whether positive affect predicts mortality among people with diabetes and among a comparison group of people with no chronic health conditions...
  20. pmc Acute responses to opioidergic blockade as a biomarker of hedonic eating among obese women enrolled in a mindfulness-based weight loss intervention trial
    Ashley E Mason
    University of California San Francisco Osher Center for Integrative Medicine, 1545 Divisadero Street 4th Floor, San Francisco, CA, USA Electronic address
    Appetite 91:311-20. 2015
    ....
  21. pmc Exaggerated neurobiological sensitivity to threat as a mechanism linking anxiety with increased risk for diseases of aging
    Aoife O'Donovan
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Neurosci Biobehav Rev 37:96-108. 2013
    ..Chronic inflammation, in turn, increases risk for diseases of aging. Exaggerated neurobiological sensitivity to threat may thus be a treatment target for reducing disease risk in anxious individuals...
  22. pmc Leptin concentrations in response to acute stress predict subsequent intake of comfort foods
    A Janet Tomiyama
    Department of Psychology, UCLA, Los Angeles, CA, USA
    Physiol Behav 107:34-9. 2012
    ..Increasing leptin during the stressor predicted lower intake of comfort food. These initial findings suggest that acute changes in leptin may be one of the factors modulating down the consumption of comfort food following stress...
  23. doi request reprint Glucocorticoids. Mood, memory, and mechanisms
    Owen M Wolkowitz
    Department of Psychiatry, University of California San Francisco UCSF School of Medicine, San Francisco, California, USA
    Ann N Y Acad Sci 1179:19-40. 2009
    ..The article concludes with a conceptual model of glucocorticoid actions in the brain that may lead to novel therapeutic opportunities...
  24. pmc Shorter leukocyte telomere length in midlife women with poor sleep quality
    Aric A Prather
    Robert Wood Johnson Foundation Health and Society Scholars Program, Center for Health and Community, University of California San Francisco, 3333 California Street, Suite 465, San Francisco, CA 94118, USA
    J Aging Res 2011:721390. 2011
    ..Conclusions. This study provides the first evidence that poor sleep quality explains significant variation in LTL, a marker of cellular aging...
  25. doi request reprint Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection
    Elizabeth H Blackburn
    Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA
    Science 350:1193-8. 2015
    ..These and other recent findings highlight both causal and potentiating roles for telomere attrition in human diseases. ..
  26. pmc Leukocyte telomere length and mortality in the National Health and Nutrition Examination Survey, 1999-2002
    Belinda L Needham
    From the aDepartment of Epidemiology and Center for Social Epidemiology and Population Health, University of Michigan, Ann Arbor, MI bDivision of General Medical Disciplines, Stanford University, Stanford, CA cDepartment of Psychiatry, dDivision of General Internal Medicine, and eDepartment of Biochemistry and Biophysics, University of California, San Francisco, CA
    Epidemiology 26:528-35. 2015
    ..We also examined moderating effects of age, sex, race/ethnicity, and education...
  27. pmc Race-Ethnicity, Poverty, Urban Stressors, and Telomere Length in a Detroit Community-based Sample
    Arline T Geronimus
    Stanford University, Stanford, CA, USA University of Michigan, Ann Arbor, MI, USA
    J Health Soc Behav 56:199-224. 2015
    ..They point to health impacts of social identity as contingent, the products of structurally rooted biopsychosocial processes. ..
  28. pmc Excessive Sugar Consumption May Be a Difficult Habit to Break: A View From the Brain and Body
    Matthew S Tryon
    Departments of Nutrition M S T, K L S, K D L, P J H and Molecular Biosciences P J H, School of Veterinary Medicine, and Division of Gastroenterology and Hepatology V M, School of Medicine, University of California, Davis, and Stress Biology and Nutrition Research Laboratory K D L, Obesity and Metabolism Research Unit, Western Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Davis, California 95616 and Department of Psychiatry E S E, A E M, R B, University of California, San Francisco, San Francisco, California 94143
    J Clin Endocrinol Metab 100:2239-47. 2015
    ..Rodent studies suggest that sugar consumption may activate a glucocorticoid-metabolic-brain-negative feedback pathway, which may turn off the stress response and thereby reinforce habitual sugar overconsumption...
  29. pmc Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls-preliminary findings
    Daniel Lindqvist
    Department of Psychiatry, University of California San Francisco UCSF School of Medicine, San Francisco, CA, United States Department of Clinical Sciences, Section for Psychiatry, Lund University, Baravägen 1, SE 221 85 Lund, Sweden Electronic address
    Psychiatry Res 224:168-74. 2014
    ..These preliminary data are consistent with oxidative stress being associated with smaller total HC and CA3&DG subfield volumes. ..
  30. pmc Maternal estriol concentrations in early gestation predict infant telomere length
    Sonja Entringer
    Departments of Pediatrics S E, C B, P D W, Obstetrics and Gynecology P D W, Epidemiology P D W, and Psychiatry and Human Behavior P D W, University of California, Irvine California 92697 Department of Obstetrics, Gynecology, and Reproductive Sciences H N S, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 Departments of Psychiatry E S E, and Biochemistry and Biophysics E H B, University of California, San Francisco, San Francisco, California 94143 and Institute for Medical Psychology S E, C B, Charite University Medicine, 10117 Berlin, Germany
    J Clin Endocrinol Metab 100:267-73. 2015
    ..The initial setting of telomere length (TL) in early life has important implications for telomere maintenance and related disorders throughout the life span. However, little is known about the predictors of this initial setting...
  31. doi request reprint Posttraumatic stress disorder is associated with emotional eating
    Lisa S Talbot
    San Francisco VA Medical Center, San Francisco, California 94121, USA
    J Trauma Stress 26:521-5. 2013
    ..Findings suggest the importance of future longitudinal research to understand whether emotional eating contributes to the high rates of obesity, diabetes, and heart disease in PTSD. ..
  32. doi request reprint Mitochondrial DNA copy number is reduced in male combat veterans with PTSD
    Francesco Saverio Bersani
    Department of Psychiatry, University of California San Francisco, San Francisco, CA, USA Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 64:10-7. 2016
    ..The present study assessed mtDNAcn in male combat-exposed veterans with PTSD compared to those without PTSD as well as its correlation with clinical scales...
  33. doi request reprint Anxiety disorders and accelerated cellular ageing
    Josine E Verhoeven
    Josine E Verhoeven, MSc, Dóra Révész, MSc, Patricia van Oppen, PhD, Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands Elissa S Epel, PhD, Owen M Wolkowitz, MD, Department of Psychiatry, University of California, San Francisco, School of Medicine, San Francisco, California, USA Brenda W J H Penninx, PhD, Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands
    Br J Psychiatry 206:371-8. 2015
    ..Anxiety disorders increase the risk of onset of several ageing-related somatic conditions, which might be the consequence of accelerated cellular ageing...
  34. pmc The reward-based eating drive scale: a self-report index of reward-based eating
    Elissa S Epel
    Department of Psychiatry, University of California San Francisco, San Francisco, California, United States of America UCSF Center for Obesity Assessment, Study, and Treatment, San Francisco, California, United States of America
    PLoS ONE 9:e101350. 2014
    ..Given the heterogeneity of obesity, unique brief profiling of the reward-based aspect of obesity using a self-report instrument such as the RED scale may be critical for customizing effective treatments in the general population. ..
  35. pmc Clues to maintaining calorie restriction? Psychosocial profiles of successful long-term restrictors
    Angela C Incollingo Belsky
    Department of Psychology, University of California, Los Angeles, CA, USA
    Appetite 79:106-12. 2014
    ..Paralleling a movement toward personalized medicine, this study points toward a personalized behavioral medicine model in behavioral nutrition and treatment of overweight/obesity...
  36. pmc Black sheep get the blues: a psychobiological model of social rejection and depression
    George M Slavich
    Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143 0848, USA
    Neurosci Biobehav Rev 35:39-45. 2010
    ..This response also may be moderated by several factors, including prior life stress, prior depression, and genes implicated in stress reactivity...
  37. doi request reprint Socioeconomic status in relation to early menarche among black and white girls
    Dejana Braithwaite
    Department of Epidemiology and Biostatistics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 185 Berry Street, Lobby 4 Suite 5700, San Francisco, CA 94107, USA
    Cancer Causes Control 20:713-20. 2009
    ..Early menarche is a risk factor for breast cancer. We investigated the variation in age at menarche by socioeconomic status (SES) and race...
  38. ncbi request reprint When blue turns to grey: do stress and depression accelerate cell aging?
    Owen M Wolkowitz
    World J Biol Psychiatry 9:2-5. 2008
  39. ncbi request reprint Flattened cortisol rhythms in metastatic breast cancer patients
    Heather C Abercrombie
    Department of Psychiatry, University of Wisconsin Medical School, 6001 Research Park Blvd, Madison, WI 53719, USA
    Psychoneuroendocrinology 29:1082-92. 2004
    ..These findings suggest that the cortisol diurnal slope may have important but different correlates in healthy women versus those with breast cancer...
  40. ncbi request reprint Sex differences in stress responses: social rejection versus achievement stress
    Laura R Stroud
    Brown University Centers for Behavioral and Preventive Medicine, Providence, Rhode Island 02903, USA
    Biol Psychiatry 52:318-27. 2002
    ..In particular, we predicted that women would show greater responses to social rejection stressors, whereas men would demonstrate greater responses to achievement stressors...
  41. pmc Why egalitarianism might be good for your health: physiological thriving during stressful intergroup encounters
    Wendy Berry Mendes
    Department of Psychology, Harvard University, Cambridge, MA 02138, USA
    Psychol Sci 18:991-8. 2007
    ..Egalitarianism may have physical and psychological benefits for people living in a diverse society...