Elissa S Epel

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Accelerated telomere shortening in response to life stress
    Elissa S Epel
    Department of Psychiatry, University of California, 3333 California Street, Suite 465, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:17312-5. 2004
  2. ncbi Cell aging in relation to stress arousal and cardiovascular disease risk factors
    Elissa S Epel
    UCSF Department of Psychiatry, San Francisco, CA, USA
    Psychoneuroendocrinology 31:277-87. 2006
  3. pmc Stress biology and aging mechanisms: toward understanding the deep connection between adaptation to stress and longevity
    Elissa S Epel
    Department of Psychiatry, University of California, San Francisco
    J Gerontol A Biol Sci Med Sci 69:S10-6. 2014
  4. doi How "reversible" is telomeric aging?
    Elissa Epel
    University of California, San Francisco, San Francisco, CA 94143, USA
    Cancer Prev Res (Phila) 5:1163-8. 2012
  5. pmc The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men
    Elissa S Epel
    University of California, San Francisco, Department of Psychiatry, San Francisco, CA, 94143, USA
    Aging (Albany NY) 1:81-8. 2008
  6. pmc Dynamics of telomerase activity in response to acute psychological stress
    Elissa S Epel
    Department of Psychiatry, University of California, San Francisco, 3333 Calif St, Suite 465, San Francisco, CA 94143, USA
    Brain Behav Immun 24:531-9. 2010
  7. pmc Dietary restraint and telomere length in pre- and postmenopausal women
    Amy Kiefer
    UCSF Department of Psychiatry, University of California, San Francisco, California, USA
    Psychosom Med 70:845-9. 2008
  8. pmc Can meditation slow rate of cellular aging? Cognitive stress, mindfulness, and telomeres
    Elissa Epel
    University of California San Francisco, Department of Psychiatry, San Francisco, California 94143, USA
    Ann N Y Acad Sci 1172:34-53. 2009
  9. ncbi Psychological and metabolic stress: a recipe for accelerated cellular aging?
    Elissa S Epel
    University of California, Department of Psychiatry, San Francisco, CA 94143, USA
    Hormones (Athens) 8:7-22. 2009
  10. pmc Effects of a mindfulness-based intervention on mindful eating, sweets consumption, and fasting glucose levels in obese adults: data from the SHINE randomized controlled trial
    Ashley E Mason
    Osher Center for Integrative Medicine, University of California San Francisco UCSF, 1545 Divisadero Street, 4th Floor, San Francisco, CA, 94115, USA
    J Behav Med 39:201-13. 2016

Research Grants

Detail Information

Publications70

  1. pmc Accelerated telomere shortening in response to life stress
    Elissa S Epel
    Department of Psychiatry, University of California, 3333 California Street, Suite 465, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:17312-5. 2004
    ..These findings have implications for understanding how, at the cellular level, stress may promote earlier onset of age-related diseases...
  2. ncbi Cell aging in relation to stress arousal and cardiovascular disease risk factors
    Elissa S Epel
    UCSF Department of Psychiatry, San Francisco, CA, USA
    Psychoneuroendocrinology 31:277-87. 2006
    ..These findings may implicate telomerase as a novel and important mediator of the effects of psychological stress on physical health and disease...
  3. pmc Stress biology and aging mechanisms: toward understanding the deep connection between adaptation to stress and longevity
    Elissa S Epel
    Department of Psychiatry, University of California, San Francisco
    J Gerontol A Biol Sci Med Sci 69:S10-6. 2014
    ..This will require interdisciplinary novel approaches that hold much promise for understanding and intervening in human chronic disease. ..
  4. doi How "reversible" is telomeric aging?
    Elissa Epel
    University of California, San Francisco, San Francisco, CA 94143, USA
    Cancer Prev Res (Phila) 5:1163-8. 2012
    ..Cancer Prev Res; 5(10); 1163-8. ©2012 AACR...
  5. pmc The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men
    Elissa S Epel
    University of California, San Francisco, Department of Psychiatry, San Francisco, CA, 94143, USA
    Aging (Albany NY) 1:81-8. 2008
    ..0 (95% CI: 1.1 - 8.2). This is the first demonstration that rate of telomere length change (TLC) predicts mortality and thus may be a useful prognostic factor for longevity...
  6. pmc Dynamics of telomerase activity in response to acute psychological stress
    Elissa S Epel
    Department of Psychiatry, University of California, San Francisco, 3333 Calif St, Suite 465, San Francisco, CA 94143, USA
    Brain Behav Immun 24:531-9. 2010
    ....
  7. pmc Dietary restraint and telomere length in pre- and postmenopausal women
    Amy Kiefer
    UCSF Department of Psychiatry, University of California, San Francisco, California, USA
    Psychosom Med 70:845-9. 2008
    ....
  8. pmc Can meditation slow rate of cellular aging? Cognitive stress, mindfulness, and telomeres
    Elissa Epel
    University of California San Francisco, Department of Psychiatry, San Francisco, California 94143, USA
    Ann N Y Acad Sci 1172:34-53. 2009
    ..Aspects of this model are currently being tested in ongoing trials of mindfulness meditation...
  9. ncbi Psychological and metabolic stress: a recipe for accelerated cellular aging?
    Elissa S Epel
    University of California, Department of Psychiatry, San Francisco, CA 94143, USA
    Hormones (Athens) 8:7-22. 2009
    ..Certain psychological temperaments at high risk of this stress cascade (mainly anxiety prone), gene-environment interactions, and potential interventions for interrupting the stress-aging cascade are discussed...
  10. pmc Effects of a mindfulness-based intervention on mindful eating, sweets consumption, and fasting glucose levels in obese adults: data from the SHINE randomized controlled trial
    Ashley E Mason
    Osher Center for Integrative Medicine, University of California San Francisco UCSF, 1545 Divisadero Street, 4th Floor, San Francisco, CA, 94115, USA
    J Behav Med 39:201-13. 2016
    ..Increases in mindful eating may contribute to the effects of mindfulness-based weight loss interventions on eating of sweets and fasting glucose levels...
  11. doi Depression gets old fast: do stress and depression accelerate cell aging?
    Owen M Wolkowitz
    Department of Psychiatry, University of California School of Medicine, San Francisco, California, USA
    Depress Anxiety 27:327-38. 2010
    ....
  12. doi Chronic psychological stress and racial disparities in body mass index change between Black and White girls aged 10-19
    A Janet Tomiyama
    Department of Psychology, University of California, Los Angeles, 90095 1563, USA
    Ann Behav Med 45:3-12. 2013
    ..One of the largest health disparities in the USA is in obesity rates between Black and White females...
  13. doi Global arginine bioavailability, a marker of nitric oxide synthetic capacity, is decreased in PTSD and correlated with symptom severity and markers of inflammation
    Francesco Saverio Bersani
    Department of Psychiatry, University of California San Francisco, San Francisco, CA, United States Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy
    Brain Behav Immun 52:153-60. 2016
    ....
  14. pmc Multisystem resiliency moderates the major depression-telomere length association: findings from the Heart and Soul Study
    Eli Puterman
    University of California San Francisco, 3333 California Street Suite 465, San Francisco, CA 94143 0848, United States Electronic address
    Brain Behav Immun 33:65-73. 2013
    ..Further research should explore the cognitive, neural, and other physiological pathways through which multisystem resiliency may confer biological benefit...
  15. pmc Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings
    Owen M Wolkowitz
    Department of Psychiatry, University of California San Francisco School of Medicine, San Francisco, California, United States of America
    PLoS ONE 6:e17837. 2011
    ..We sought to determine if leukocyte telomeres are shortened in Major Depressive Disorder (MDD), whether this is a function of lifetime depression exposure and whether this is related to putative mediators, oxidation and inflammation...
  16. pmc Leukocyte telomere length predicts SSRI response in major depressive disorder: A preliminary report
    Christina M Hough
    Department of Psychiatry, University of California San Francisco UCSF School of Medicine, San Francisco, CA, USA
    Mol Neuropsychiatry 2:88-96. 2016
    ..Our data suggest that short LTL may serve as a vulnerability index of poorer response to SSRI treatment, but this needs examination in larger samples...
  17. pmc PBMC telomerase activity, but not leukocyte telomere length, correlates with hippocampal volume in major depression
    Owen M Wolkowitz
    Department of Psychiatry, University of California San Francisco UCSF School of Medicine, San Francisco, CA, USA Electronic address
    Psychiatry Res 232:58-64. 2015
    ....
  18. pmc Stress appraisals and cellular aging: a key role for anticipatory threat in the relationship between psychological stress and telomere length
    Aoife O'Donovan
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Brain Behav Immun 26:573-9. 2012
    ..Exaggerated anticipatory threat appraisals may be a common and modifiable psychological mechanism of psychological stress effects on cellular aging...
  19. pmc Effects of a mindfulness-based weight loss intervention in adults with obesity: A randomized clinical trial
    JENNIFER DAUBENMIER
    Osher Center for Integrative Medicine, University of California, San Francisco, California, USA
    Obesity (Silver Spring) 24:794-804. 2016
    ..To determine whether adding mindfulness-based eating and stress management practices to a diet-exercise program improves weight loss and metabolic syndrome components...
  20. pmc Cumulative inflammatory load is associated with short leukocyte telomere length in the Health, Aging and Body Composition Study
    Aoife O'Donovan
    Department of Psychiatry, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 6:e19687. 2011
    ..However, in spite of the proposed causal links between inflammatory activity and LTL, there is little clinical evidence in support of their covariation and interaction...
  21. pmc Exercise mitigates cumulative associations between stress and BMI in girls age 10 to 19
    Eli Puterman
    Department of Psychiatry, University of California San Francisco
    Health Psychol 35:191-4. 2016
    ..We hypothesized that in addition to these main effects, long-term physical activity mitigates the relationship between long-term stress and BMI increase...
  22. pmc Oxidative stress, inflammation and treatment response in major depression
    Daniel Lindqvist
    Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California San Francisco UCSF School of Medicine, San Francisco, CA, United States Lund University, Faculty of Medicine, Department of Clinical Sciences, Psychiatry, Lund, Sweden Electronic address
    Psychoneuroendocrinology 76:197-205. 2016
    ..The goals of the present study are to investigate markers of inflammation and oxidative stress in unmedicated MDD subjects and controls and test the relationship between these markers and antidepressant response in MDD subjects...
  23. pmc Higher serum DHEA concentrations before and after SSRI treatment are associated with remission of major depression
    Christina M Hough
    Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California, San Francisco UCSF School of Medicine, San Francisco, CA, USA
    Psychoneuroendocrinology 77:122-130. 2016
    ..Nonetheless, the role of endogenous DHEA(S) levels in major depressive disorder (MDD) and antidepressant outcomes remains unclear...
  24. pmc Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging
    Daniel Lindqvist
    Department of Clinical Sciences, Section for Psychiatry, Lund University, Lund, Sweden Department of Psychiatry, University of California San Francisco UCSF, School of Medicine, San Francisco, CA, USA
    Neurosci Biobehav Rev 55:333-64. 2015
    ..A deeper understanding of cellular aging in psychiatric illnesses could lead to re-conceptualizing them as systemic illnesses with manifestations inside and outside the brain and could identify new treatment targets. ..
  25. pmc Putting the brakes on the "drive to eat": Pilot effects of naltrexone and reward-based eating on food cravings among obese women
    Ashley E Mason
    University of California, San Francisco, Osher Center for Integrative Medicine, United States Electronic address
    Eat Behav 19:53-6. 2015
    ....
  26. doi Association of dimensional psychological health measures with telomere length in male war veterans
    Francesco S Bersani
    Department of Psychiatry, University of California San Francisco, San Francisco, CA, USA Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy
    J Affect Disord 190:537-42. 2016
    ..We explored the association between dimensional psychopathological measures and telomere length (TL) in granulocytes among veterans independent of psychiatric diagnosis...
  27. pmc Gender differences in the prospective associations of self-reported sleep quality with biomarkers of systemic inflammation and coagulation: findings from the Heart and Soul Study
    Aric A Prather
    Department of Psychiatry, University of California, 3333 California St, Suite 465, San Francisco, CA 94118, United States
    J Psychiatr Res 47:1228-35. 2013
    ..Further research is necessary to elucidate the pathways that underlie gender-specific associations between subjective sleep quality and markers of inflammation and coagulation as this may help clarify gender disparities in CHD. ..
  28. pmc Serum BDNF levels before treatment predict SSRI response in depression
    Owen M Wolkowitz
    Department of Psychiatry, University of California, San Francisco School of Medicine, San Francisco, CA 94143, United States
    Prog Neuropsychopharmacol Biol Psychiatry 35:1623-30. 2011
    ..It is also unknown whether pre-treatment serum BDNF levels predict antidepressant response...
  29. pmc Impact of a Mindfulness-Based Weight-Loss Intervention on Sleep Quality Among Adults with Obesity: Data from the SHINE Randomized Controlled Trial
    Elizabeth Adler
    1 UCSF Osher Center for Integrative Medicine, San Francisco, CA
    J Altern Complement Med . 2016
    ..The aim of this study was to compare the effects of a mindfulness-based weight-loss intervention with an active control on self-reported sleep quality among adults with obesity...
  30. pmc Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women
    Aric A Prather
    Department of Psychiatry, University of California, San Francisco, United States Electronic address
    Brain Behav Immun 47:155-62. 2015
    ..These findings provide preliminary evidence that poorer global sleep quality is related to telomere length in several immune cell types, which may serve as a pathway linking sleep and disease risk in obese individuals. ..
  31. pmc Maternal estriol concentrations in early gestation predict infant telomere length
    Sonja Entringer
    Departments of Pediatrics S E, C B, P D W, Obstetrics and Gynecology P D W, Epidemiology P D W, and Psychiatry and Human Behavior P D W, University of California, Irvine California 92697 Department of Obstetrics, Gynecology, and Reproductive Sciences H N S, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 Departments of Psychiatry E S E, and Biochemistry and Biophysics E H B, University of California, San Francisco, San Francisco, California 94143 and Institute for Medical Psychology S E, C B, Charite University Medicine, 10117 Berlin, Germany
    J Clin Endocrinol Metab 100:267-73. 2015
    ..The initial setting of telomere length (TL) in early life has important implications for telomere maintenance and related disorders throughout the life span. However, little is known about the predictors of this initial setting...
  32. pmc Accelerated cell aging in female APOE-ε4 carriers: implications for hormone therapy use
    Emily G Jacobs
    Robert Wood Johnson Foundation Health and Society Scholars Program, Center for Health and Community, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 8:e54713. 2013
    ..The results suggest that hormone use might buffer against accelerated cell aging in mid-life women at risk for dementia. Importantly, for non-carrier women there was no evidence that HT conferred protective effects on telomere dynamics...
  33. pmc Maternal psychosocial stress during pregnancy is associated with newborn leukocyte telomere length
    Sonja Entringer
    Department of Pediatrics, University of California, Irvine, School of Medicine, Irvine, CA 92697, USA
    Am J Obstet Gynecol 208:134.e1-7. 2013
    ..The objective of the present study was to determine how early in life this effect of stress on LTL is apparent by quantifying the association of maternal psychosocial stress during pregnancy with newborn telomere length...
  34. ncbi The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men
    Elissa S Epel
    University of California, San Francisco, Department of Psychiatry, San Francisco, CA, 94143, USA
    Aging (Albany NY) 1:81-8. 2008
    ..0 (95% CI: 1.1 - 8.2). This is the first demonstration that rate of telomere length change (TLC) predicts mortality and thus may be a useful prognostic factor for longevity...
  35. pmc Race-Ethnicity, Poverty, Urban Stressors, and Telomere Length in a Detroit Community-based Sample
    Arline T Geronimus
    Stanford University, Stanford, CA, USA University of Michigan, Ann Arbor, MI, USA
    J Health Soc Behav 56:199-224. 2015
    ..They point to health impacts of social identity as contingent, the products of structurally rooted biopsychosocial processes. ..
  36. pmc Cortisol/DHEA ratio and hippocampal volume: A pilot study in major depression and healthy controls
    Rowen O Jin
    Department of Psychiatry, University of California, San Francisco, School of Medicine, CA, 94143, United States
    Psychoneuroendocrinology 72:139-46. 2016
    ....
  37. pmc Soda and cell aging: associations between sugar-sweetened beverage consumption and leukocyte telomere length in healthy adults from the National Health and Nutrition Examination Surveys
    Cindy W Leung
    Cindy W Leung is with the Center for Health and Community, School of Medicine, University of California, San Francisco Barbara A Laraia is with the School of Public Health, University of California, Berkeley Belinda Needham is with the Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor David H Rehkopf is with the Department of Medicine, Stanford University, Palo Alto, CA Nancy E Adler and Elissa S Epel are with the Center for Health and Community and the Department of Psychiatry, School of Medicine, University of California, San Francisco Jue Lin and Elizabeth H Blackburn are with the Department of Biochemistry and Biophysics, University of California, San Francisco
    Am J Public Health 104:2425-31. 2014
    ..We tested whether leukocyte telomere length maintenance, which underlies healthy cellular aging, provides a link between sugar-sweetened beverage (SSB) consumption and the risk of cardiometabolic disease...
  38. pmc Indirect effect of financial strain on daily cortisol output through daily negative to positive affect index in the Coronary Artery Risk Development in Young Adults Study
    Eli Puterman
    Department of Psychiatry, University of California, San Francisco, United States Electronic address
    Psychoneuroendocrinology 38:2883-9. 2013
    ..A combined affect index may be a more sensitive and powerful measure than either negative or positive affect alone, tapping the burden of chronic financial strain, and its effects on biology. ..
  39. doi Posttraumatic stress disorder is associated with emotional eating
    Lisa S Talbot
    San Francisco VA Medical Center, San Francisco, California 94121, USA
    J Trauma Stress 26:521-5. 2013
    ..Findings suggest the importance of future longitudinal research to understand whether emotional eating contributes to the high rates of obesity, diabetes, and heart disease in PTSD. ..
  40. pmc Leptin concentrations in response to acute stress predict subsequent intake of comfort foods
    A Janet Tomiyama
    Department of Psychology, UCLA, Los Angeles, CA, USA
    Physiol Behav 107:34-9. 2012
    ..Increasing leptin during the stressor predicted lower intake of comfort food. These initial findings suggest that acute changes in leptin may be one of the factors modulating down the consumption of comfort food following stress...
  41. pmc Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease
    Ramin Farzaneh-Far
    Division of Cardiology, Room 5G1, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA
    JAMA 303:250-7. 2010
    ..Increased dietary intake of marine omega-3 fatty acids is associated with prolonged survival in patients with coronary heart disease. However, the mechanisms underlying this protective effect are poorly understood...
  42. pmc Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood
    Sonja Entringer
    Department of Pediatrics, University of California, Irvine, CA 92697, USA
    Proc Natl Acad Sci U S A 108:E513-8. 2011
    ..This observation may help shed light on an important biological pathway underlying the developmental origins of adult health and disease risk...
  43. pmc Change in Leukocyte Telomere Length Predicts Mortality in Patients with Stable Coronary Heart Disease from the Heart and Soul Study
    Sarah E Goglin
    Department of Medicine, University of California San Francisco, San Francisco, CA, 94143, United States of America
    PLoS ONE 11:e0160748. 2016
    ..Short telomere length independently predicts mortality in patients with coronary heart disease. Whether 5-year change in telomere length predicts subsequent mortality in patients with coronary heart disease has not been evaluated...
  44. pmc Anger is associated with increased IL-6 stress reactivity in women, but only among those low in social support
    Eli Puterman
    Department of Psychiatry, School of Medicine, University of California, San Francisco, CA, USA
    Int J Behav Med 21:936-45. 2014
    ..Affective states (anger, fear, and anxiety) predict interleukin-6 (IL-6) reactivity to acute stress; in turn, this reactivity predicts risk of cardiovascular disease progression...
  45. pmc Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls-preliminary findings
    Daniel Lindqvist
    Department of Psychiatry, University of California San Francisco UCSF School of Medicine, San Francisco, CA, United States Department of Clinical Sciences, Section for Psychiatry, Lund University, Baravägen 1, SE 221 85 Lund, Sweden Electronic address
    Psychiatry Res 224:168-74. 2014
    ..These preliminary data are consistent with oxidative stress being associated with smaller total HC and CA3&DG subfield volumes. ..
  46. pmc The reward-based eating drive scale: a self-report index of reward-based eating
    Elissa S Epel
    Department of Psychiatry, University of California San Francisco, San Francisco, California, United States of America UCSF Center for Obesity Assessment, Study, and Treatment, San Francisco, California, United States of America
    PLoS ONE 9:e101350. 2014
    ..Given the heterogeneity of obesity, unique brief profiling of the reward-based aspect of obesity using a self-report instrument such as the RED scale may be critical for customizing effective treatments in the general population. ..
  47. pmc Exaggerated neurobiological sensitivity to threat as a mechanism linking anxiety with increased risk for diseases of aging
    Aoife O'Donovan
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Neurosci Biobehav Rev 37:96-108. 2013
    ..Chronic inflammation, in turn, increases risk for diseases of aging. Exaggerated neurobiological sensitivity to threat may thus be a treatment target for reducing disease risk in anxious individuals...
  48. pmc Chronic stress elevates telomerase activity in rats
    Annaliese K Beery
    Robert Wood Johnson Health and Society Scholar at University of California at San Francisco, San Francisco, CA 04143, USA
    Biol Lett 8:1063-6. 2012
    ..This significant increase suggests a potential mechanism for resilience to stress-related replicative senescence...
  49. pmc Telomere shortening in formerly abused and never abused women
    Janice Humphreys
    Department of Family Health Care Nursing, School of Nursing, University of California, San Francisco, CA 94143, USA
    Biol Res Nurs 14:115-23. 2012
    ..Findings from this descriptive study suggest a link between IPV exposure, duration of IPV-related stress, and telomere length molecular mechanisms that regulate cellular aging...
  50. ncbi Flattened cortisol rhythms in metastatic breast cancer patients
    Heather C Abercrombie
    Department of Psychiatry, University of Wisconsin Medical School, 6001 Research Park Blvd, Madison, WI 53719, USA
    Psychoneuroendocrinology 29:1082-92. 2004
    ..These findings suggest that the cortisol diurnal slope may have important but different correlates in healthy women versus those with breast cancer...
  51. pmc Shorter leukocyte telomere length in midlife women with poor sleep quality
    Aric A Prather
    Robert Wood Johnson Foundation Health and Society Scholars Program, Center for Health and Community, University of California San Francisco, 3333 California Street, Suite 465, San Francisco, CA 94118, USA
    J Aging Res 2011:721390. 2011
    ..Conclusions. This study provides the first evidence that poor sleep quality explains significant variation in LTL, a marker of cellular aging...
  52. pmc Acute responses to opioidergic blockade as a biomarker of hedonic eating among obese women enrolled in a mindfulness-based weight loss intervention trial
    Ashley E Mason
    University of California San Francisco Osher Center for Integrative Medicine, 1545 Divisadero Street 4th Floor, San Francisco, CA, USA Electronic address
    Appetite 91:311-20. 2015
    ....
  53. pmc Poor sleep quality potentiates stress-induced cytokine reactivity in postmenopausal women with high visceral abdominal adiposity
    Aric A Prather
    Department of Psychiatry, University of California, San Francisco, United States Electronic address
    Brain Behav Immun 35:155-62. 2014
    ..This research may help elucidate the complex link between sleep, obesity and inflammatory disease risk. ..
  54. pmc Leukocyte telomere length and mortality in the National Health and Nutrition Examination Survey, 1999-2002
    Belinda L Needham
    From the aDepartment of Epidemiology and Center for Social Epidemiology and Population Health, University of Michigan, Ann Arbor, MI bDivision of General Medical Disciplines, Stanford University, Stanford, CA cDepartment of Psychiatry, dDivision of General Internal Medicine, and eDepartment of Biochemistry and Biophysics, University of California, San Francisco, CA
    Epidemiology 26:528-35. 2015
    ..We also examined moderating effects of age, sex, race/ethnicity, and education...
  55. doi Positive affect uniquely predicts lower risk of mortality in people with diabetes
    Judith Tedlie Moskowitz
    Osher Center for Integrative Medicine, University of California, San Francisco, CA 94115, USA
    Health Psychol 27:S73-82. 2008
    ..To determine whether positive affect predicts mortality among people with diabetes and among a comparison group of people with no chronic health conditions...
  56. doi Glucocorticoids. Mood, memory, and mechanisms
    Owen M Wolkowitz
    Department of Psychiatry, University of California San Francisco UCSF School of Medicine, San Francisco, California, USA
    Ann N Y Acad Sci 1179:19-40. 2009
    ..The article concludes with a conceptual model of glucocorticoid actions in the brain that may lead to novel therapeutic opportunities...
  57. pmc Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS)
    Nicole Maninger
    Department of Psychiatry, University of California San Francisco, School of Medicine, San Francisco 94143, USA
    Front Neuroendocrinol 30:65-91. 2009
    ..Accumulating data suggest abnormal DHEA and/or DHEAS concentrations in several neuropsychiatric conditions. The evidence that DHEA and DHEAS may be fruitful targets for pharmacotherapy in some conditions is reviewed...
  58. doi A Prospective Investigation of Prenatal Mood and Childbirth Perceptions in an Ethnically Diverse, Low-Income Sample
    Jayme L Congdon
    Department of Pediatrics at Stanford University, Stanford, CA, USA
    Birth 43:159-66. 2016
    ..Few studies have examined prenatal mood as a means to identify women at risk for negative childbirth experiences. We explore associations between prenatal mood and birth perceptions in a socioeconomically diverse, American sample...
  59. doi Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection
    Elizabeth H Blackburn
    Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA
    Science 350:1193-8. 2015
    ..These and other recent findings highlight both causal and potentiating roles for telomere attrition in human diseases. ..
  60. pmc Excessive Sugar Consumption May Be a Difficult Habit to Break: A View From the Brain and Body
    Matthew S Tryon
    Departments of Nutrition M S T, K L S, K D L, P J H and Molecular Biosciences P J H, School of Veterinary Medicine, and Division of Gastroenterology and Hepatology V M, School of Medicine, University of California, Davis, and Stress Biology and Nutrition Research Laboratory K D L, Obesity and Metabolism Research Unit, Western Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Davis, California 95616 and Department of Psychiatry E S E, A E M, R B, University of California, San Francisco, San Francisco, California 94143
    J Clin Endocrinol Metab 100:2239-47. 2015
    ..Rodent studies suggest that sugar consumption may activate a glucocorticoid-metabolic-brain-negative feedback pathway, which may turn off the stress response and thereby reinforce habitual sugar overconsumption...
  61. doi Socioeconomic status in relation to early menarche among black and white girls
    Dejana Braithwaite
    Department of Epidemiology and Biostatistics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 185 Berry Street, Lobby 4 Suite 5700, San Francisco, CA 94107, USA
    Cancer Causes Control 20:713-20. 2009
    ..Early menarche is a risk factor for breast cancer. We investigated the variation in age at menarche by socioeconomic status (SES) and race...
  62. pmc Black sheep get the blues: a psychobiological model of social rejection and depression
    George M Slavich
    Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143 0848, USA
    Neurosci Biobehav Rev 35:39-45. 2010
    ..This response also may be moderated by several factors, including prior life stress, prior depression, and genes implicated in stress reactivity...
  63. doi Hypothalamic-pituitary-adrenal axis dysregulation and cortisol activity in obesity: A systematic review
    Angela C Incollingo Rodriguez
    University of California, Los Angeles, CA 90095, USA
    Psychoneuroendocrinology 62:301-18. 2015
    ..Although there is substantial evidence of differential hypothalamic-pituitary-adrenal (HPA) axis activity in both generalized and abdominal obesity, consistent trends in obesity-related HPA axis perturbations have yet to be identified...
  64. doi Mitochondrial DNA copy number is reduced in male combat veterans with PTSD
    Francesco Saverio Bersani
    Department of Psychiatry, University of California San Francisco, San Francisco, CA, USA Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 64:10-7. 2016
    ..The present study assessed mtDNAcn in male combat-exposed veterans with PTSD compared to those without PTSD as well as its correlation with clinical scales...
  65. doi Anxiety disorders and accelerated cellular ageing
    Josine E Verhoeven
    Josine E Verhoeven, MSc, Dóra Révész, MSc, Patricia van Oppen, PhD, Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands Elissa S Epel, PhD, Owen M Wolkowitz, MD, Department of Psychiatry, University of California, San Francisco, School of Medicine, San Francisco, California, USA Brenda W J H Penninx, PhD, Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands
    Br J Psychiatry 206:371-8. 2015
    ..Anxiety disorders increase the risk of onset of several ageing-related somatic conditions, which might be the consequence of accelerated cellular ageing...
  66. pmc Clues to maintaining calorie restriction? Psychosocial profiles of successful long-term restrictors
    Angela C Incollingo Belsky
    Department of Psychology, University of California, Los Angeles, CA, USA
    Appetite 79:106-12. 2014
    ..Paralleling a movement toward personalized medicine, this study points toward a personalized behavioral medicine model in behavioral nutrition and treatment of overweight/obesity...
  67. ncbi Stress, eating and the reward system
    Tanja C Adam
    University of California, San Francisco, Department of Psychiatry, United States
    Physiol Behav 91:449-58. 2007
    ....
  68. ncbi When blue turns to grey: do stress and depression accelerate cell aging?
    Owen M Wolkowitz
    World J Biol Psychiatry 9:2-5. 2008
  69. pmc Why egalitarianism might be good for your health: physiological thriving during stressful intergroup encounters
    Wendy Berry Mendes
    Department of Psychology, Harvard University, Cambridge, MA 02138, USA
    Psychol Sci 18:991-8. 2007
    ..Egalitarianism may have physical and psychological benefits for people living in a diverse society...
  70. ncbi Sex differences in stress responses: social rejection versus achievement stress
    Laura R Stroud
    Brown University Centers for Behavioral and Preventive Medicine, Providence, Rhode Island 02903, USA
    Biol Psychiatry 52:318-27. 2002
    ..In particular, we predicted that women would show greater responses to social rejection stressors, whereas men would demonstrate greater responses to achievement stressors...

Research Grants1

  1. Depression, Stress & Health: Role of Anabolic Hormones
    Elissa Epel; Fiscal Year: 2006
    ..If warranted, future research will compare effects of stress reduction and hormonal supplementation on mood and disease risk. ..