DANIEL EITZMAN

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc Mebendazole reduces vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice
    Jintao Wang
    University of Michigan, Department of Internal Medicine, Cardiovascular Research Center, Ann Arbor, Michigan, United States of America
    PLoS ONE 9:e90146. 2014
  2. pmc Leptin-induced endothelial dysfunction is mediated by sympathetic nervous system activity
    Jintao Wang
    Department of Internal Medicine, Cardiovascular Research Center, University of Michigan, Ann Arbor, MI
    J Am Heart Assoc 2:e000299. 2013
  3. ncbi request reprint Leptin in thrombosis and atherosclerosis
    Hui Wang
    University of Michigan Cardiovascular Research Center, 7301A MSRB III, 1150 West Medical Center Drive, Ann Arbor, MI 48109 0644, USA
    Curr Pharm Des 20:641-5. 2014
  4. pmc Obesity-induced endothelial dysfunction is prevented by deficiency of P-selectin glycoprotein ligand-1
    Hui Wang
    Department of Internal Medicine, Cardiovascular Research Center, University of Michigan, Ann Arbor, Michigan, USA
    Diabetes 61:3219-27. 2012
  5. ncbi request reprint Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice
    D T Eitzman
    Cardiovascular Research Center and Division of Molecular Medicine and Human Genetics, Department of Internal Medicine, and the Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor, MI 49109 0644, USA
    Blood 95:577-80. 2000
  6. ncbi request reprint Homozygosity for factor V Leiden leads to enhanced thrombosis and atherosclerosis in mice
    Daniel T Eitzman
    Division of Cardiology, University of Michigan Medical Center, Ann Arbor 48109 0644, USA
    Circulation 111:1822-5. 2005
  7. ncbi request reprint Lethal perinatal thrombosis in mice resulting from the interaction of tissue factor pathway inhibitor deficiency and factor V Leiden
    Daniel T Eitzman
    Division of Cardiology, University of Michigan Medical Center, Ann Arbor, Mich 48109 0644, USA
    Circulation 105:2139-42. 2002
  8. ncbi request reprint Plasminogen activator inhibitor-1 deficiency protects against atherosclerosis progression in the mouse carotid artery
    D T Eitzman
    Divisions of Cardiology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
    Blood 96:4212-5. 2000
  9. ncbi request reprint Hyperlipidemia promotes thrombosis after injury to atherosclerotic vessels in apolipoprotein E-deficient mice
    D T Eitzman
    Cardiovascular Research Center, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor 48109 0644, USA
    Arterioscler Thromb Vasc Biol 20:1831-4. 2000
  10. doi request reprint Animal models of thrombosis
    Peter F Bodary
    Department of Movement Science, School of Kinesiology, University of Michigan Medical School, Ann Arbor, MI 48109 2214, USA
    Curr Opin Hematol 16:342-6. 2009

Collaborators

Detail Information

Publications27

  1. pmc Mebendazole reduces vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice
    Jintao Wang
    University of Michigan, Department of Internal Medicine, Cardiovascular Research Center, Ann Arbor, Michigan, United States of America
    PLoS ONE 9:e90146. 2014
    ..Mebendazole is effective at inhibiting vascular smooth muscle cell proliferation and migration, and neointimal formation following arterial injury in mice. ..
  2. pmc Leptin-induced endothelial dysfunction is mediated by sympathetic nervous system activity
    Jintao Wang
    Department of Internal Medicine, Cardiovascular Research Center, University of Michigan, Ann Arbor, MI
    J Am Heart Assoc 2:e000299. 2013
    ..The aim of this study was to investigate the effect of leptin treatment on endothelial function and the role of the local sympathetic nervous system in mediating these effects...
  3. ncbi request reprint Leptin in thrombosis and atherosclerosis
    Hui Wang
    University of Michigan Cardiovascular Research Center, 7301A MSRB III, 1150 West Medical Center Drive, Ann Arbor, MI 48109 0644, USA
    Curr Pharm Des 20:641-5. 2014
    ..Therapeutic strategies designed to block leptin-mediated signaling events in cells contributing to vascular disease may prove beneficial in obese subjects at risk for vascular complications. ..
  4. pmc Obesity-induced endothelial dysfunction is prevented by deficiency of P-selectin glycoprotein ligand-1
    Hui Wang
    Department of Internal Medicine, Cardiovascular Research Center, University of Michigan, Ann Arbor, Michigan, USA
    Diabetes 61:3219-27. 2012
    ..Psgl-1 inhibition may be a useful treatment strategy for targeting vascular disease associated with obesity...
  5. ncbi request reprint Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice
    D T Eitzman
    Cardiovascular Research Center and Division of Molecular Medicine and Human Genetics, Department of Internal Medicine, and the Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor, MI 49109 0644, USA
    Blood 95:577-80. 2000
    ..01 compared to WT mice). These results suggest that endogenous fibrinolysis and its regulation by PAI-1 and VN have important roles in the development of occlusive vascular thrombosis after vascular injury. (Blood. 2000;95:577-580)..
  6. ncbi request reprint Homozygosity for factor V Leiden leads to enhanced thrombosis and atherosclerosis in mice
    Daniel T Eitzman
    Division of Cardiology, University of Michigan Medical Center, Ann Arbor 48109 0644, USA
    Circulation 111:1822-5. 2005
    ..Although the impact of FVL on the development of venous thrombosis is well established, its effect on arterial thrombosis and atherosclerosis is controversial...
  7. ncbi request reprint Lethal perinatal thrombosis in mice resulting from the interaction of tissue factor pathway inhibitor deficiency and factor V Leiden
    Daniel T Eitzman
    Division of Cardiology, University of Michigan Medical Center, Ann Arbor, Mich 48109 0644, USA
    Circulation 105:2139-42. 2002
    ..Variation in the expression of tissue factor pathway inhibitor (TFPI) has also been proposed as a risk factor for venous thrombosis and has been shown to enhance the prothrombotic effect of FVL in vitro...
  8. ncbi request reprint Plasminogen activator inhibitor-1 deficiency protects against atherosclerosis progression in the mouse carotid artery
    D T Eitzman
    Divisions of Cardiology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
    Blood 96:4212-5. 2000
    ..Blood. 2000;96:4212-4215)..
  9. ncbi request reprint Hyperlipidemia promotes thrombosis after injury to atherosclerotic vessels in apolipoprotein E-deficient mice
    D T Eitzman
    Cardiovascular Research Center, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor 48109 0644, USA
    Arterioscler Thromb Vasc Biol 20:1831-4. 2000
    ....
  10. doi request reprint Animal models of thrombosis
    Peter F Bodary
    Department of Movement Science, School of Kinesiology, University of Michigan Medical School, Ann Arbor, MI 48109 2214, USA
    Curr Opin Hematol 16:342-6. 2009
    ..The use of animal models of thrombosis provides a critical tool for the discovery and initial testing of novel therapies for vascular thrombosis...
  11. ncbi request reprint Recent advances in understanding endogenous fibrinolysis: implications for molecular-based treatment of vascular disorders
    Peter F Bodary
    Division of Cardiology, University of Michigan Medical Center, 7315 MSRB III, 1150 W Medical Center Drive, Ann Arbor, MI 49109 0644, USA
    Expert Rev Mol Med 4:1-10. 2002
    ..Since alterations in fibrinolytic capacity appear to affect thrombus formation in animal models, there is considerable interest in the pharmacological manipulation of fibrinolysis...
  12. ncbi request reprint Murine models of vascular thrombosis (Eitzman series)
    Randal J Westrick
    Departments of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA
    Arterioscler Thromb Vasc Biol 27:2079-93. 2007
    ..This review will highlight some of the recent developments in the field of thrombosis using mouse models and how these studies are expanding our knowledge of thrombotic disease...
  13. ncbi request reprint Competitive bidding for interventional cardiology supplies: lessons learned during round 2
    Kim A Eagle
    Department of Internal Medicine, University of Michigan Health System, Ann Arbor, USA
    Am J Manag Care 8:384-8. 2002
    ..To assess the magnitude of savings and develop concepts for "best strategies" in reducing costs in the purchasing of high-technology, high-cost materials used in coronary interventions and electrophysiologic treatments...
  14. ncbi request reprint Alpha-galactosidase A deficiency leads to increased tissue fibrin deposition and thrombosis in mice homozygous for the factor V Leiden mutation
    Yuechun Shen
    Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
    Stroke 37:1106-8. 2006
    ..Fabry disease, an X-linked lysosomal storage disorder attributable to alpha-galactosidase A (GLA) deficiency, is associated with premature vascular events that may be thrombotic in nature...
  15. ncbi request reprint Effect of leptin on arterial thrombosis following vascular injury in mice
    Peter F Bodary
    Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
    JAMA 287:1706-9. 2002
    ..In addition, other actions of leptin have been proposed, including an in vitro effect on platelet aggregation. Thus, the elevated plasma leptin levels in obese individuals may promote vascular thrombosis...
  16. ncbi request reprint Recombinant leptin promotes atherosclerosis and thrombosis in apolipoprotein E-deficient mice
    Peter F Bodary
    Division of Cardiovascular Medicine, Department of Internal Medicine, niversity of Michigan Medical Center, Ann Arbor, MI, USA
    Arterioscler Thromb Vasc Biol 25:e119-22. 2005
    ..The direct role of leptin in vascular disease remains controversial. The objective of this study was to examine the effects of leptin treatment on atherosclerosis and thrombosis in atherosclerotic-prone mice...
  17. ncbi request reprint Alpha-galactosidase A deficiency accelerates atherosclerosis in mice with apolipoprotein E deficiency
    Peter F Bodary
    Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, Mich, USA
    Circulation 111:629-32. 2005
    ..Glycosphingolipids have been shown to accumulate in human atherosclerotic lesions, although their role in atherogenesis is unclear...
  18. pmc Monocyte chemoattractant protein-1 deficiency protects against visceral fat-induced atherosclerosis
    Miina K Ohman
    Cardiovascular Research Center, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109 0644, USA
    Arterioscler Thromb Vasc Biol 30:1151-8. 2010
    ..To determine the role of monocyte chemoattractant protein-1 (Mcp-1) on the progression of visceral fat-induced atherosclerosis...
  19. ncbi request reprint Fabry disease in mice is associated with age-dependent susceptibility to vascular thrombosis
    Daniel T Eitzman
    Division of Cardiology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA
    J Am Soc Nephrol 14:298-302. 2003
    ....
  20. ncbi request reprint Plasminogen activator inhibitor-1 in vascular thrombosis
    Randal J Westrick
    Department of Human Genetics, University of Michigan Medical Center, and the Ann Arbor Veterans Administration Hospital, Ann Arbor, Michigan, USA
    Curr Drug Targets 8:966-1002. 2007
    ....
  21. pmc Visceral adipose tissue inflammation accelerates atherosclerosis in apolipoprotein E-deficient mice
    Miina K Ohman
    University of Michigan, Department of Internal Medicine, Division of Cardiology, Ann Arbor 48109 0644, USA
    Circulation 117:798-805. 2008
    ..Fat inflammation may play an important role in comorbidities associated with obesity such as atherosclerosis...
  22. ncbi request reprint Targeting MCP-1 to reduce vascular complications of obesity
    Miina K Ohman
    Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, Michigan 48109, USA
    Recent Pat Cardiovasc Drug Discov 4:164-76. 2009
    ..Since MCP-1 promotes atherosclerosis, inhibition of MCP-1 may be effective in reducing the vascular risk associated with obesity...
  23. pmc P-selectin glycoprotein ligand-1 regulates adhesive properties of the endothelium and leukocyte trafficking into adipose tissue
    Hana M Russo
    Department of Internal Medicine, University of Michigan, Ann Arbor, 48109 0644, USA
    Circ Res 107:388-97. 2010
    ..Adhesive interactions between endothelial cells and leukocytes affect leukocyte trafficking in adipose tissue. The role of P-selectin glycoprotein ligand-1 (Psgl-1) in this process is unclear...
  24. pmc Heparin cofactor II inhibits arterial thrombosis after endothelial injury
    Li He
    Division of Hematology, Department of Internal Medicine, Washington University, St Louis, Missouri 63110, USA
    J Clin Invest 109:213-9. 2002
    ..This abnormality was corrected by infusion of purified HCII but not ovalbumin. These observations suggest that HCII might inhibit thrombosis in the arterial circulation...
  25. ncbi request reprint Atherosclerosis in mice is not affected by a reduction in tissue factor expression
    Rachel E Tilley
    Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA
    Arterioscler Thromb Vasc Biol 26:555-62. 2006
    ..To determine whether tissue factor (TF) contributes to the progression of atherosclerotic lesions in mice...
  26. ncbi request reprint Leptin regulates neointima formation after arterial injury through mechanisms independent of blood pressure and the leptin receptor/STAT3 signaling pathways involved in energy balance
    Peter F Bodary
    Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, USA
    Arterioscler Thromb Vasc Biol 27:70-6. 2007
    ..The relevant cellular leptin receptor pools and signaling pathways involved in leptin-related vascular phenotypes in vivo are unclear...
  27. ncbi request reprint Adiponectin: vascular protection from the fat?
    Peter F Bodary
    Arterioscler Thromb Vasc Biol 26:235-6. 2006