- Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMCTara G Edmonds
Department of Molecular and Cellular Pathology, University of Alabama at Birmingham, 701 19th Street South, Birmingham, AL 35294, USA
Virology 408:1-13. 2010..In PBMC, NAb activity can be analyzed either within a single or multiple cycles of replication. These results represent advancement toward a standardizable PBMC-based neutralization assay for assessing HIV-1 vaccine immunogen efficacy...
- Optimized Replicating Renilla Luciferase Reporter HIV-1 Utilizing Novel Internal Ribosome Entry Site Elements for Native Nef Expression and FunctionMichael O Alberti
1 Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama
AIDS Res Hum Retroviruses 31:1278-96. 2015..T2A reporter virus. In summary, reporter viruses comprising the "6ATRi" element promise to augment HIV-1 vaccine and transmission research approaches requiring a sensitive reporter readout combined with wild-type Nef function. ..
- Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived macrophagesChristina Ochsenbauer
Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Virol 86:2715-28. 2012....