- Telomerase as a diagnostic and therapeutic target for cancerL Austin Doyle
Greenebaum Cancer Center, 22 South Greene Street, Baltimore, MD 21201, USA
Expert Rev Anticancer Ther 2:217-25. 2002..Due to its widespread occurrence in cancer and its crucial role in the maintenance of the tumor, telomerase is an attractive target for cancer diagnosis and treatment...
- Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)L Austin Doyle
The University of Maryland Greenebaum Cancer Center, 22 South Greene Street, Baltimore, MD 21201, USA
Oncogene 22:7340-58. 2003..More prospective studies are needed, preferably combining BCRP protein or mRNA quantification with functional assays, in order to determine the contribution of BCRP to drug resistance in human cancers...