N Maritza Dowling

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Measurement and control of bias in patient reported outcomes using multidimensional item response theory
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI, USA
    BMC Med Res Methodol 16:63. 2016
  2. pmc The mediational effects of FDG hypometabolism on the association between cerebrospinal fluid biomarkers and neurocognitive function
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI, USA Alzheimer s Disease Research Center, University of Wisconsin, Madison, WI, USA Electronic address
    Neuroimage 105:357-68. 2015
  3. pmc Characterization of vascular disease risk in postmenopausal women and its association with cognitive performance
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA
    PLoS ONE 8:e68741. 2013
  4. pmc A model for the design and implementation of a participant recruitment registry for clinical studies of older adults
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin Madison, Madison, WI 53792 4675, USA
    Clin Trials 9:204-14. 2012
  5. pmc Neuropathological associates of multiple cognitive functions in two community-based cohorts of older adults
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53792, USA
    J Int Neuropsychol Soc 17:602-14. 2011
  6. pmc Latent structure and factorial invariance of a neuropsychological test battery for the study of preclinical Alzheimer's disease
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, K6 446 Box 4675, J5 M194, Clinical Sciences Center, 600 Highland Avenue, Madison, WI 53792 4675, USA
    Neuropsychology 24:742-56. 2010
  7. pmc Cerebrospinal Fluid Markers of Alzheimer's Disease Pathology and Microglial Activation are Associated with Altered White Matter Microstructure in Asymptomatic Adults at Risk for Alzheimer's Disease
    Kelsey E Melah
    Wisconsin Alzheimer s Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    J Alzheimers Dis 50:873-86. 2016
  8. pmc Cerebrospinal fluid ratios with Aβ42 predict preclinical brain β-amyloid accumulation
    Annie M Racine
    Alzheimer s Disease Research Center, University of Wisconsin School of Medicine and Public Health, USA, Madison, WI 53705 Neuroscience Training Program, University of Wisconsin Madison, USA, Madison, WI 53705 Neuroscience and Public Policy Program, University of Wisconsin Madison, USA, Madison, WI 53705 Institute on Aging, University of Wisconsin Madison, USA, Madison, WI 53706
    Alzheimers Dement (Amst) 2:27-38. 2016
  9. pmc Using predictors of hormone therapy use to model the healthy user bias: how does healthy user status influence cognitive effects of hormone therapy?
    Carey E Gleason
    Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin Madison, School of Medicine and Public Health, Madison, WI, USA
    Menopause 19:524-33. 2012
  10. pmc Effects of Hormone Therapy on Cognition and Mood in Recently Postmenopausal Women: Findings from the Randomized, Controlled KEEPS-Cognitive and Affective Study
    Carey E Gleason
    School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America Geriatric Research, Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States of America Wisconsin Alzheimer s Disease Research Center, Madison, Wisconsin, United States of America
    PLoS Med 12:e1001833; discussion e1001833. 2015

Collaborators

Detail Information

Publications24

  1. pmc Measurement and control of bias in patient reported outcomes using multidimensional item response theory
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI, USA
    BMC Med Res Methodol 16:63. 2016
    ....
  2. pmc The mediational effects of FDG hypometabolism on the association between cerebrospinal fluid biomarkers and neurocognitive function
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI, USA Alzheimer s Disease Research Center, University of Wisconsin, Madison, WI, USA Electronic address
    Neuroimage 105:357-68. 2015
    ..While intriguing, the hypothesized mediational relationships require further validation...
  3. pmc Characterization of vascular disease risk in postmenopausal women and its association with cognitive performance
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA
    PLoS ONE 8:e68741. 2013
    ..This study investigated heterogeneity in CV risk factor profiles and its association with demographic, genetic, and cognitive variables...
  4. pmc A model for the design and implementation of a participant recruitment registry for clinical studies of older adults
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin Madison, Madison, WI 53792 4675, USA
    Clin Trials 9:204-14. 2012
    ..Inadequate participation may undermine the pace and direction of new treatment discoveries...
  5. pmc Neuropathological associates of multiple cognitive functions in two community-based cohorts of older adults
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53792, USA
    J Int Neuropsychol Soc 17:602-14. 2011
    ..Results show that cognition is complexly determined by multiple disease substrates. Neuropathological variables and brain weight contributed approximately a third to half of the explained variance in different cognitive domains...
  6. pmc Latent structure and factorial invariance of a neuropsychological test battery for the study of preclinical Alzheimer's disease
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, K6 446 Box 4675, J5 M194, Clinical Sciences Center, 600 Highland Avenue, Madison, WI 53792 4675, USA
    Neuropsychology 24:742-56. 2010
    ....
  7. pmc Cerebrospinal Fluid Markers of Alzheimer's Disease Pathology and Microglial Activation are Associated with Altered White Matter Microstructure in Asymptomatic Adults at Risk for Alzheimer's Disease
    Kelsey E Melah
    Wisconsin Alzheimer s Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    J Alzheimers Dis 50:873-86. 2016
    ..However, overproduction of inflammatory compounds may exacerbate neural damage in AD. AD pathology accumulates years before diagnosis, yet the extent to which neuroinflammation is involved in the earliest disease stages is unknown...
  8. pmc Cerebrospinal fluid ratios with Aβ42 predict preclinical brain β-amyloid accumulation
    Annie M Racine
    Alzheimer s Disease Research Center, University of Wisconsin School of Medicine and Public Health, USA, Madison, WI 53705 Neuroscience Training Program, University of Wisconsin Madison, USA, Madison, WI 53705 Neuroscience and Public Policy Program, University of Wisconsin Madison, USA, Madison, WI 53705 Institute on Aging, University of Wisconsin Madison, USA, Madison, WI 53706
    Alzheimers Dement (Amst) 2:27-38. 2016
    ..Biomarkers are urgently needed for the critical yet understudied preclinical stage of Alzheimer's disease (AD)...
  9. pmc Using predictors of hormone therapy use to model the healthy user bias: how does healthy user status influence cognitive effects of hormone therapy?
    Carey E Gleason
    Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin Madison, School of Medicine and Public Health, Madison, WI, USA
    Menopause 19:524-33. 2012
    ..This study investigated the phenomenon known as the healthy user bias by equating hormone therapy (HT) use (past or current) with healthy user status...
  10. pmc Effects of Hormone Therapy on Cognition and Mood in Recently Postmenopausal Women: Findings from the Randomized, Controlled KEEPS-Cognitive and Affective Study
    Carey E Gleason
    School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America Geriatric Research, Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, Wisconsin, United States of America Wisconsin Alzheimer s Disease Research Center, Madison, Wisconsin, United States of America
    PLoS Med 12:e1001833; discussion e1001833. 2015
    ..The ancillary Cognitive and Affective Study (KEEPS-Cog) of the Kronos Early Estrogen Prevention Study (KEEPS) examined the effects of up to 4 y of MHT on cognition and mood in recently postmenopausal women...
  11. pmc Awareness of memory abilities in community-dwelling older adults with suspected dementia and mild cognitive impairment
    Feng Lin
    School of Nursing, Department of Medicine, School of Medicine and Public Health, University of Wisconsin Madison, Madison, WI, USA
    Dement Geriatr Cogn Disord 30:83-92. 2010
    ....
  12. pmc Cognitive Effects of Soy Isoflavones in Patients with Alzheimer's Disease
    Carey E Gleason
    Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin Madison, School of Medicine and Public Health, Madison, WI, USA
    J Alzheimers Dis 47:1009-19. 2015
    ..In a previous trial, treatment with soy isoflavones was associated with improved nonverbal memory, construction abilities, verbal fluency, and speeded dexterity compared to treatment with placebo in cognitively healthy older adults...
  13. pmc Associations between white matter microstructure and amyloid burden in preclinical Alzheimer's disease: A multimodal imaging investigation
    Annie M Racine
    Alzheimer s Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA
    Neuroimage Clin 4:604-14. 2014
    ....
  14. pmc White matter microstructure in late middle-age: Effects of apolipoprotein E4 and parental family history of Alzheimer's disease
    Nagesh Adluru
    Waisman Laboratory for Brain Imaging and Behavior, Madison, WI, USA
    Neuroimage Clin 4:730-42. 2014
    ..The purpose of this cross-sectional study was to assess the effect of two well-known risk factors for AD, parental family history and APOE4 genotype...
  15. pmc Midlife measurements of white matter microstructure predict subsequent regional white matter atrophy in healthy adults
    Martina Ly
    Geriatric Research Education and Clinical Center, William S Middleton Memorial Veteran s Hospital, Madison, Wisconsin Department of Medicine, Wisconsin Alzheimer s Disease Research Center, University of Wisconsin, Madison, Wisconsin Neuroscience Training Program, University of Wisconsin, Madison, Wisconsin
    Hum Brain Mapp 35:2044-54. 2014
    ..The aim of this study was to determine if baseline fractional anisotropy (FA), obtained from diffusion tensor imaging (DTI) predicts volume change over a 4-year interval...
  16. pmc Longitudinal changes in menopausal symptoms comparing women randomized to low-dose oral conjugated estrogens or transdermal estradiol plus micronized progesterone versus placebo: the Kronos Early Estrogen Prevention Study
    Nanette Santoro
    1Department of Obstetrics and Gynecology 2Department of Biostatistics, University of Colorado School of Medicine, Aurora, CO 3Department of Obstetrics, Gynecology and Women s Health and Neurosciences, Albert Einstein College of Medicine, Bronx, NY 4Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT 5Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, NY 6Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY 7Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA 8Utah Foundation for Biomedical Research, Salt Lake City, UT 9Department of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 10Department of Obstetrics and Gynecology, University of California at San Francisco, San Francisco, CA 11Departments of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 12Kronos Longevity Research Institute, Phoenix, AZ 13Department of Medicine and Public Health, University of Wisconsin, Madison, WI 14Atherosclerosis Research Unit, University of Southern California, Los Angeles, CA 15Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 16Departments of Surgery and Physiology and Biomedical Engineering, Mayo Clinic, Rochester, All India Institute of Medical Sciences
    Menopause . 2016
    ..The objective of the present study was to compare the efficacy of two forms of menopausal hormone therapy in alleviating vasomotor symptoms, insomnia, and irritability in early postmenopausal women during 4 years...
  17. pmc Insulin Resistance is Associated with Higher Cerebrospinal Fluid Tau Levels in Asymptomatic APOEɛ4 Carriers
    Erika J Starks
    Wisconsin Alzheimer s Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    J Alzheimers Dis 46:525-33. 2015
    ..However, the extent to which IR is associated with AD pathology in the cognitively asymptomatic stages of preclinical AD remains unclear...
  18. pmc Amyloid burden, neuronal function, and cognitive decline in middle-aged adults at risk for Alzheimer's disease
    Ozioma C Okonkwo
    1 Geriatric Research Education and Clinical Center, William S Middleton Memorial VA Hospital, Madison, Wisconsin
    J Int Neuropsychol Soc 20:422-33. 2014
    ..002) as the top three measures that best discriminated the groups. These findings suggest that early memory test performance might serve a more clinically pivotal role in forecasting future cognitive course than is currently presumed...
  19. pmc An approach for estimating item sensitivity to within-person change over time: An illustration using the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog)
    N Maritza Dowling
    Department of Biostatistics and Medical Informatics, University of Wisconsin Madison
    Psychol Assess 28:1576-1585. 2016
    ..PsycINFO Database Record..
  20. pmc Effects of hormone therapy on brain structure: A randomized controlled trial
    Kejal Kantarci
    From the Departments of Radiology K K, S M Z, J L G, P V, M L S, C R J, Health Sciences Research N T, T G L, K R B, W A R, Internal Medicine L T S, Neurology W A R, and Surgery and Physiology and Biomedical Engineering V M M, Mayo Clinic, Rochester, MN Department of Medicine C E G, S A, School of Medicine and Public Health, University of Wisconsin and Geriatric Research, Education and Clinical Center, William S Middleton Memorial, Veterans Hospital, Madison, WI Department of Neurology W W, Emory University, Atlanta, GA and Department of Biostatistics and Medical Informatics N M D, University of Wisconsin, Madison
    Neurology 87:887-96. 2016
    ..To investigate the effects of hormone therapy on brain structure in a randomized, double-blinded, placebo-controlled trial in recently postmenopausal women...
  21. pmc Imaging-based enrichment criteria using deep learning algorithms for efficient clinical trials in mild cognitive impairment
    Vamsi K Ithapu
    Department of Computer Sciences, University of Wisconsin Madison, Madison, WI, USA Wisconsin Alzheimer s Disease Research Center, University of Wisconsin Madison, Madison, WI, USA Electronic address
    Alzheimers Dement 11:1489-99. 2015
    ....
  22. pmc Cerebral blood flow is diminished in asymptomatic middle-aged adults with maternal history of Alzheimer's disease
    Ozioma C Okonkwo
    Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, WI, USA
    Cereb Cortex 24:978-88. 2014
    ....
  23. pmc Common Sense Model Factors Affecting African Americans' Willingness to Consult a Healthcare Provider Regarding Symptoms of Mild Cognitive Impairment
    Carey E Gleason
    Wisconsin Alzheimer s Disease Research Center, Madison, WI Division of Geriatrics, Department of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin, Madison, WI Electronic address
    Am J Geriatr Psychiatry 24:537-46. 2016
    ..Using the common sense model (CSM) of illness perception, we sought to clarify processes promoting timely diagnosis of mild cognitive impairment (MCI) for African American patients...
  24. pmc Chronotropic Response and Cognitive Function in a Cohort at Risk for Alzheimer's Disease
    Lena L Law
    Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, WI, USA
    J Alzheimers Dis 56:351-359. 2017
    ....