Samuel R Dominguez

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. doi request reprint Kawasaki disease in a pediatric intensive care unit: a case-control study
    Samuel R Dominguez
    Department of Pediatrics, University of Colorado Denver School of Medicine, Denver, Colorado, USA
    Pediatrics 122:e786-90. 2008
  2. pmc Multiplex MassTag-PCR for respiratory pathogens in pediatric nasopharyngeal washes negative by conventional diagnostic testing shows a high prevalence of viruses belonging to a newly recognized rhinovirus clade
    Samuel R Dominguez
    Department of Pediatrics, The Children s Hospital, University of Colorado Denver School of Medicine, Aurora, CO, USA
    J Clin Virol 43:219-22. 2008
  3. pmc Detection of four human coronaviruses in respiratory infections in children: a one-year study in Colorado
    Samuel R Dominguez
    Department of Pediatrics, The Children s Hospital, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    J Med Virol 81:1597-604. 2009
  4. pmc Genomic analysis of 16 Colorado human NL63 coronaviruses identifies a new genotype, high sequence diversity in the N-terminal domain of the spike gene and evidence of recombination
    Samuel R Dominguez
    Department of Pediatrics, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 E 19th Ave, Room P18 9403B, Aurora, CO 80045, USA
    J Gen Virol 93:2387-98. 2012
  5. ncbi request reprint Mycoplasma hominis endocarditis in a child with a complex congenital heart defect
    Samuel R Dominguez
    University of Colorado School of Medicine, Denver, CO 80010, USA
    Pediatr Infect Dis J 25:851-2. 2006
  6. pmc Identification of the Receptor-Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1
    Zhaohui Qian
    MOH Key Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Science, Beijing, China Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA
    J Virol 89:8816-27. 2015
  7. pmc Human coronavirus HKU1 infection of primary human type II alveolar epithelial cells: cytopathic effects and innate immune response
    Samuel R Dominguez
    Department of Pediatrics, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, United States of America
    PLoS ONE 8:e70129. 2013
  8. doi request reprint Kawasaki disease and the pediatric gastroenterologist: a diagnostic challenge
    Mohammed Eladawy
    Ain Shams University Department of Pediatrics, University of Colorado School of Medicine and Children s Hospital, Aurora, CO 80045, USA
    J Pediatr Gastroenterol Nutr 56:297-9. 2013
  9. pmc Myocardial Strain and Strain Rate in Kawasaki Disease: Range, Recovery, and Relationship to Systemic Inflammation/Coronary Artery Dilation
    Benjamin Frank
    Department of Pediatrics and Section of Cardiology, Children s Hospital Colorado University of Colorado, Denver, USA
    J Clin Exp Cardiolog 7:. 2016
  10. ncbi request reprint Blinded case-control study of the relationship between human coronavirus NL63 and Kawasaki syndrome
    Samuel R Dominguez
    Department of Pediatrics, The Children s Hospital, University of Colorado Health Science Center, Denver, CO, USA
    J Infect Dis 194:1697-701. 2006

Collaborators

Detail Information

Publications15

  1. doi request reprint Kawasaki disease in a pediatric intensive care unit: a case-control study
    Samuel R Dominguez
    Department of Pediatrics, University of Colorado Denver School of Medicine, Denver, Colorado, USA
    Pediatrics 122:e786-90. 2008
    ..We conducted a case-control study to ascertain the clinical presentations, risk factors, and clinical outcomes of children who had Kawasaki disease and were admitted to the ICU of our children's hospital...
  2. pmc Multiplex MassTag-PCR for respiratory pathogens in pediatric nasopharyngeal washes negative by conventional diagnostic testing shows a high prevalence of viruses belonging to a newly recognized rhinovirus clade
    Samuel R Dominguez
    Department of Pediatrics, The Children s Hospital, University of Colorado Denver School of Medicine, Aurora, CO, USA
    J Clin Virol 43:219-22. 2008
    ..Respiratory infections are the most common infectious diseases in humans worldwide and are a leading cause of death in children less than 5 years of age...
  3. pmc Detection of four human coronaviruses in respiratory infections in children: a one-year study in Colorado
    Samuel R Dominguez
    Department of Pediatrics, The Children s Hospital, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    J Med Virol 81:1597-604. 2009
    ..Our data raise the possibility that HCoV may play a role in gastrointestinal and CNS disease. Additional studies are needed to investigate the potential roles of HCoVs in these diseases...
  4. pmc Genomic analysis of 16 Colorado human NL63 coronaviruses identifies a new genotype, high sequence diversity in the N-terminal domain of the spike gene and evidence of recombination
    Samuel R Dominguez
    Department of Pediatrics, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 E 19th Ave, Room P18 9403B, Aurora, CO 80045, USA
    J Gen Virol 93:2387-98. 2012
    ..Ten different amino acid sequences were found in the NTD of the spike protein among these NL63 strains and the 75 partial published sequences of NTDs from strains found at different times throughout the world...
  5. ncbi request reprint Mycoplasma hominis endocarditis in a child with a complex congenital heart defect
    Samuel R Dominguez
    University of Colorado School of Medicine, Denver, CO 80010, USA
    Pediatr Infect Dis J 25:851-2. 2006
    ..This is the first reported case of Mycoplasma endocarditis in a child and suggests consideration of this organism as a cause of culture-negative endocarditis...
  6. pmc Identification of the Receptor-Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1
    Zhaohui Qian
    MOH Key Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Science, Beijing, China Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA
    J Virol 89:8816-27. 2015
    ..Thus, two β-CoVs in group A, HKU1 and murine CoV, have evolved to use different regions of their spike glycoproteins to recognize their respective receptor proteins...
  7. pmc Human coronavirus HKU1 infection of primary human type II alveolar epithelial cells: cytopathic effects and innate immune response
    Samuel R Dominguez
    Department of Pediatrics, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, United States of America
    PLoS ONE 8:e70129. 2013
    ..Furthermore, these studies demonstrate that human alveolar cells can be used to isolate and study novel human respiratory viruses that cause lower respiratory tract disease. ..
  8. doi request reprint Kawasaki disease and the pediatric gastroenterologist: a diagnostic challenge
    Mohammed Eladawy
    Ain Shams University Department of Pediatrics, University of Colorado School of Medicine and Children s Hospital, Aurora, CO 80045, USA
    J Pediatr Gastroenterol Nutr 56:297-9. 2013
    ..In the present study, we report a series of patients with KD in whom a gastroenterology consult was obtained before consideration of the diagnosis of KD...
  9. pmc Myocardial Strain and Strain Rate in Kawasaki Disease: Range, Recovery, and Relationship to Systemic Inflammation/Coronary Artery Dilation
    Benjamin Frank
    Department of Pediatrics and Section of Cardiology, Children s Hospital Colorado University of Colorado, Denver, USA
    J Clin Exp Cardiolog 7:. 2016
    ..Some KD patients demonstrate echocardiographic evidence of depressed myocardial mechanics. However, the incidence, etiology, and reversibility of abnormal mechanics in KD patients remain undefined...
  10. ncbi request reprint Blinded case-control study of the relationship between human coronavirus NL63 and Kawasaki syndrome
    Samuel R Dominguez
    Department of Pediatrics, The Children s Hospital, University of Colorado Health Science Center, Denver, CO, USA
    J Infect Dis 194:1697-701. 2006
    ..These data suggest that, although HCoV-NL63 was circulating in children in our community during the time of the study, the prevalence of infection with HCoV-NL63 was not greater in patients with KS than in control subjects...
  11. doi request reprint Advances in the treatment of Kawasaki disease
    Samuel R Dominguez
    Department of Pediatrics, Section of Infectious Diseases, Children s Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    Curr Opin Pediatr 25:103-9. 2013
    ..Although there is no conclusive body of evidence defining the best second and third-line therapies for Kawasaki patients, there have been several recent studies published describing the results of these therapies...
  12. pmc The new age of virus discovery: genomic analysis of a novel human betacoronavirus isolated from a fatal case of pneumonia
    Kathryn V Holmes
    Department of Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA
    MBio 4:e00548-12. 2013
    ....
  13. doi request reprint Epidemiology and Molecular Characteristics of Mycoplasma pneumoniae During an Outbreak of M. pneumoniae-Associated Stevens-Johnson Syndrome
    Louise K Francois Watkins
    1Epidemic Intelligence Service Centers for Disease Control and Prevention, Atlanta, Georgia, USA 2University of Colorado School of Medicine, Aurora, Colorado, USA 3Centers for Disease Control and Prevention, Atlanta, Georgia, USA 4Children s Hospital Colorado, Aurora, Colorado, USA 5Colorado Department of Public Health and Environment, Denver, CO, USA
    Pediatr Infect Dis J . 2017
    ..We describe the epidemiologic and molecular characteristics of M. pneumoniae among SJS case-patients and surrounding community members during the outbreak...
  14. doi request reprint Epidemiology and clinical characteristics of infants with human parechovirus or human herpes virus-6 detected in cerebrospinal fluid tested for enterovirus or herpes simplex virus
    Kevin Messacar
    Department of Pediatrics, Section of Hospital Medicine and Infectious Diseases, Aurora, Colorado Department of Pathology and Laboratory Medicine, Aurora, Colorado
    J Med Virol 87:829-35. 2015
    ..The clinical and fiscal impact of testing infants for HPeV and HHV-6 needs to be determined...
  15. pmc Alphacoronaviruses in New World bats: prevalence, persistence, phylogeny, and potential for interaction with humans
    Christina Osborne
    Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, United States of America
    PLoS ONE 6:e19156. 2011
    ..Further CoV surveillance studies in bats throughout the Americas are warranted...