Affiliation: University of Vermont
- A pilot randomized controlled trial of pioglitazone for the treatment of poorly controlled asthma in obesityAnne E Dixon
Division of Pulmonary and Critical Care Medicine, Given D209, 149 Beaumont Avenue, Burlington, VT, 05405, USA
Respir Res 16:143. 2015..The purpose of this study was to determine the efficacy of pioglitazone, an anti-diabetic medication which can alter circulating adipokines and have direct effects on asthmatic inflammation, in the treatment of asthma in obesity...
- Endoplasmic reticulum stress mediates house dust mite-induced airway epithelial apoptosis and fibrosisSidra M Hoffman
Department of Pathology, Vermont Lung Center University of Vermont College of Medicine, Burlington, VT 05405, USA
Respir Res 14:141. 2013..In the current study, we sought to examine the contribution of ER stress transducers in the pathogenesis of three principal facets of allergic asthma: inflammation, airway fibrosis, and airways hyperresponsiveness...
- Criteria to screen for chronic sinonasal diseaseAnne E Dixon
Department of Medicine, University of Vermont, Burlington, VT 05401, USA
Chest 136:1324-32. 2009..There are no simple, validated tools to screen for these diseases. The objective of this study was to assess instruments to assist in the diagnosis of chronic sinonasal disease...
- Rhinosinusitis and asthma: the missing linkAnne E Dixon
Vermont Lung Center, Department of Medicine, University of Vermont, Burlington, Vermont 05405, USA
Curr Opin Pulm Med 15:19-24. 2009..Finally, we will review recent data assessing the impact of treating sinonasal disease on both the development of asthma and asthma control...
- Lower airway disease in asthmatics with and without rhinitisAnne E Dixon
Department of Medicine, University of Vermont College of Medicine, Vermont Lung Center, HSRF 226, 149 Beaumont Avenue, Burlington, VT 05405, USA
Lung 186:361-8. 2008..The purpose of this study was to determine if asthma with rhinitis and asthma without rhinitis represent distinct forms of disease...
- Effect of obesity on clinical presentation and response to treatment in asthmaAnne E Dixon
University of Vermont, Burlington, VT 05401, USA
J Asthma 43:553-8. 2006..Obese and non-obese asthmatics have similar lung function abnormalities, but comorbidities and altered responses to medications may significantly affect asthma control in obese people...
- Allergic rhinitis and sinusitis in asthma: differential effects on symptoms and pulmonary functionAnne E Dixon
Pulmonary and Critical Care Medicine, University of Vermont, Burlington, 05401, USA
Chest 130:429-35. 2006..The purpose of this study was to determine the impact of self-reported allergic rhinitis and sinusitis on lower airway disease in a large cohort of participants with well-characterized asthma...
- Asthma in American Indian adults: the Strong Heart StudyAnne E Dixon
University of Vermont College of Medicine, 111 Colchester Ave, Burlington, VT 05401, USA
Chest 131:1323-30. 2007..Characterization of the impact of asthma among American Indian adults is necessary in order to design appropriate clinical and preventive measures...
- Does obesity produce a distinct asthma phenotype?Njira L Lugogo
Department of Medicine, Duke University, Durham, North Carolina, USA
J Appl Physiol (1985) 108:729-34. 2010..Although the mechanisms underlying obesity in asthma require further investigation, obesity plays a major role in the asthma epidemic and likely results in a distinct phenotype of the disease...
- The association between BMI and plasma cytokine levels in patients with acute lung injuryRenee D Stapleton
Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Vermont College of Medicine, HSRF 222, Burlington, VT 05405, USA
Chest 138:568-77. 2010..We hypothesized that cytokine response might be attenuated in patients who are obese and critically ill or that obesity might modify the relationship between plasma cytokines and clinical outcomes in ALI...
- The treatment of asthma in obesityANNE DIXON
Pulmonary and Critical Care Medicine, Given D209, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, VT 05405, USA
Expert Rev Respir Med 6:331-40. 2012..Future studies should focus on the development of therapies specifically tailored towards the treatment of asthma in obesity...
- Early intervention of therapy in asthmaAnne E Dixon
Department of Medicine, University of Vermont College of Medicine, Burlington, VT, USA
Curr Opin Pulm Med 11:51-5. 2005..Knowing the critical time to intervene in asthma is of utmost importance to clinicians and patients alike. This article reviews recent evidence that early intervention improves long-term outcomes in asthma...
- Trafficking of Th1 cells to lung: a role for selectins and a P-selectin glycoprotein-1-independent ligandJoan G Clark
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, Seattle, WA 98109, USA
Am J Respir Cell Mol Biol 30:220-7. 2004..However, our studies reveal that a ligand distinct from P-selectin glycoprotein-1 also binds these selectins in vitro and appears to play a physiologic role in in vivo emigration of Th1 lymphocytes into the lung...
- Symposium on obesity and asthma - November 2, 2006Louis Philippe Boulet
Centre de Pneumologie, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Hopital Laval, Quebec
Can Respir J 14:201-8. 2007....
- Rhinosinusitis in AsthmaANNE DIXON; Fiscal Year: 2008..At the same time it will advance our understanding of the link between the upper and lower airway in asthma and the results of these studies will guide physicians caring for asthmatic patients. ..