Anthony L DeVico

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. pmc Signature biochemical properties of broadly cross-reactive HIV-1 neutralizing antibodies in human plasma
    Mohammad M Sajadi
    Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Virol 86:5014-25. 2012
  2. pmc Identification and characterization of an immunogenic hybrid epitope formed by both HIV gp120 and human CD4 proteins
    George K Lewis
    Institute of Human Virology, Department of Medicine, University of Maryland School of Medicine, University of Maryland, Baltimore, 725 West Lombard Street, Baltimore, MD 21201, USA
    J Virol 85:13097-104. 2011
  3. pmc Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection
    Yongjun Guan
    Division of Basic Science, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Proc Natl Acad Sci U S A 106:3952-7. 2009
  4. ncbi request reprint N-terminal proteolytic processing by cathepsin G converts RANTES/CCL5 and related analogs into a truncated 4-68 variant
    Jean K Lim
    Institute of Human Virology, University of Maryland, Baltimore, 725 W Lombard Street, 6th Fl, Baltimore, MD 21201, USA
    J Leukoc Biol 80:1395-404. 2006
  5. pmc Antigenic properties of the human immunodeficiency virus transmembrane glycoprotein during cell-cell fusion
    Catherine M Finnegan
    Institute of Human Virology, University of Maryland Biotechnology Institute, University of Maryland, Baltimore, Maryland 21201, USA
    J Virol 76:12123-34. 2002
  6. ncbi request reprint Development of vaccination strategies that elicit broadly neutralizing antibodies against human immunodeficiency virus type 1 in both the mucosal and systemic immune compartments
    David M Hone
    Divisions of Basic Science and Vaccine Research, Institute of Human Virology, University of Maryland Biotechnology Institute, Baltimore, Maryland 21201, USA
    J Hum Virol 5:17-23. 2002
  7. pmc Correlation between circulating HIV-1 RNA and broad HIV-1 neutralizing antibody activity
    Mohammad M Sajadi
    Institute of Human Virology at the University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Acquir Immune Defic Syndr 57:9-15. 2011
  8. pmc Self-protection of individual CD4+ T cells against R5 HIV-1 infection by the synthesis of anti-viral CCR5 ligands
    Yongjun Guan
    Division of Basic Science and Vaccine Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 3:e3481. 2008
  9. pmc Preclinical evaluation of synthetic -2 RANTES as a candidate vaginal microbicide to target CCR5
    Tina M Kish-Catalone
    Division of Basic Sciences, Institute of Human Virology, University of Maryland Biotechnology Institute, 725 West Lombard Street, S622, Baltimore, MD 21201, USA
    Antimicrob Agents Chemother 50:1497-509. 2006
  10. ncbi request reprint CD4-induced epitopes in the HIV envelope glycoprotein, gp120
    Anthony L DeVico
    Division of Basic and Vaccine Research, Institute of Human Virology, University of Maryland Biotechnology Institute, Baltimore, MD 21201, USA
    Curr HIV Res 5:561-71. 2007

Collaborators

Detail Information

Publications15

  1. pmc Signature biochemical properties of broadly cross-reactive HIV-1 neutralizing antibodies in human plasma
    Mohammad M Sajadi
    Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Virol 86:5014-25. 2012
    ..Such biochemical properties might be exploited to reliably predict or produce broad anti-HIV immunity...
  2. pmc Identification and characterization of an immunogenic hybrid epitope formed by both HIV gp120 and human CD4 proteins
    George K Lewis
    Institute of Human Virology, Department of Medicine, University of Maryland School of Medicine, University of Maryland, Baltimore, 725 West Lombard Street, Baltimore, MD 21201, USA
    J Virol 85:13097-104. 2011
    ..These data represent a rare instance of an antibody response that is specific to a pathogen-host cell protein interaction and underscore the diversity of immunogenic CD4i epitope structures that exist during natural infection...
  3. pmc Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection
    Yongjun Guan
    Division of Basic Science, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Proc Natl Acad Sci U S A 106:3952-7. 2009
    ..These data suggest that plasma Ab repertoires can underestimate the breadth of humoral immunity, and analyses of B(Mem) should be included in studies correlating Ab specificity with protective immunity to HIV-1...
  4. ncbi request reprint N-terminal proteolytic processing by cathepsin G converts RANTES/CCL5 and related analogs into a truncated 4-68 variant
    Jean K Lim
    Institute of Human Virology, University of Maryland, Baltimore, 725 W Lombard Street, 6th Fl, Baltimore, MD 21201, USA
    J Leukoc Biol 80:1395-404. 2006
    ..These findings suggest that cathepsin G mediates a novel pathway for regulating RANTES activity and may be relevant to the role of RANTES and its analogs in preventing HIV infection...
  5. pmc Antigenic properties of the human immunodeficiency virus transmembrane glycoprotein during cell-cell fusion
    Catherine M Finnegan
    Institute of Human Virology, University of Maryland Biotechnology Institute, University of Maryland, Baltimore, Maryland 21201, USA
    J Virol 76:12123-34. 2002
    ..Such findings have important implications for HIV vaccine approaches based on gp41 intermediates...
  6. ncbi request reprint Development of vaccination strategies that elicit broadly neutralizing antibodies against human immunodeficiency virus type 1 in both the mucosal and systemic immune compartments
    David M Hone
    Divisions of Basic Science and Vaccine Research, Institute of Human Virology, University of Maryland Biotechnology Institute, Baltimore, Maryland 21201, USA
    J Hum Virol 5:17-23. 2002
    ..This paper reviews recent advances made by the authors toward the development of an HIV-1 vaccine that elicits such antibodies in both the mucosal and systemic immune compartments...
  7. pmc Correlation between circulating HIV-1 RNA and broad HIV-1 neutralizing antibody activity
    Mohammad M Sajadi
    Institute of Human Virology at the University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Acquir Immune Defic Syndr 57:9-15. 2011
    ..To examine the relationship between HIV-1 antigenic load (plasma RNA copies/mL) and broad HIV-1 neutralizing antibody activity...
  8. pmc Self-protection of individual CD4+ T cells against R5 HIV-1 infection by the synthesis of anti-viral CCR5 ligands
    Yongjun Guan
    Division of Basic Science and Vaccine Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 3:e3481. 2008
    ..These data are most consistent with an autocrine pathway of protection in this system and indicate a previously unappreciated selective pressure on the emergence of viral variants and CD4+ T cell phenotypes during HIV-1 infection...
  9. pmc Preclinical evaluation of synthetic -2 RANTES as a candidate vaginal microbicide to target CCR5
    Tina M Kish-Catalone
    Division of Basic Sciences, Institute of Human Virology, University of Maryland Biotechnology Institute, 725 West Lombard Street, S622, Baltimore, MD 21201, USA
    Antimicrob Agents Chemother 50:1497-509. 2006
    ..Overall, these preclinical studies suggest that -2 RANTES is suitable for further testing as a candidate anti-HIV-1 microbicide...
  10. ncbi request reprint CD4-induced epitopes in the HIV envelope glycoprotein, gp120
    Anthony L DeVico
    Division of Basic and Vaccine Research, Institute of Human Virology, University of Maryland Biotechnology Institute, Baltimore, MD 21201, USA
    Curr HIV Res 5:561-71. 2007
    ..This review covers the current findings related to the accessibility, antigenicity and immunogenicity of CD4-induced epitopes on gp120...
  11. pmc Soluble factors from T cells inhibiting X4 strains of HIV are a mixture of β chemokines and RNases
    Fiorenza Cocchi
    Institute of Human Virology and Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Proc Natl Acad Sci U S A 109:5411-6. 2012
    ..The antiviral mechanisms of these HIV X4-suppressive factors differ from those of the previously described HIV R5-suppressive β chemokines...
  12. ncbi request reprint Multiple pathways of amino terminal processing produce two truncated variants of RANTES/CCL5
    Jean K Lim
    Institute of Human Virology, University of Maryland Biotechnology Institute, University of Maryland, 725 W Lombard Street, Baltimore, MD 21201, USA
    J Leukoc Biol 78:442-52. 2005
    ..Such findings have important implications for understanding the immunological and HIV-suppressive activities of native RANTES...
  13. ncbi request reprint Development of an oral prime-boost strategy to elicit broadly neutralizing antibodies against HIV-1
    Anthony L DeVico
    Division of Vaccine Research, Institute of Human Virology, University of Maryland Biotechnology Institute, 725 W Lombard Street, Baltimore, MD 21201, USA
    Vaccine 20:1968-74. 2002
    ....
  14. ncbi request reprint Control of HIV-1 infection by soluble factors of the immune response
    Anthony L DeVico
    Institute of Human Virology, University of Maryland Biotechnology Institute, Baltimore, Maryland 21202, USA
    Nat Rev Microbiol 2:401-13. 2004
  15. ncbi request reprint Differential polarization of immune responses by co-administration of antigens with chemokines
    Achim Frauenschuh
    Division of Basic Science, Institute of Human Virology, University of Maryland Biotechnology Institute, 725 West Lombard Street, Baltimore, MD 21201, USA
    Vaccine 23:546-54. 2004
    ..These results are relevant towards the engineering of novel vaccine and immune-based therapies, and point to chemokines as candidate adjuvant and immunomodulatory molecules...