Frank C Detterbeck

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi Lung cancer. Invasive staging: the guidelines
    Frank C Detterbeck
    Multidisciplinary Thoracic Oncology Program, Division of Cardiothoracic Surgery, University of North Carolina, CB 7065, 108 Burnett Womack Building, Chapel Hill, NC 27599 7065, USA
    Chest 123:167S-175S. 2003
  2. ncbi Efficacy of methods of intercostal nerve blockade for pain relief after thoracotomy
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, University of North Carolina, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 80:1550-9. 2005
  3. ncbi Seeking a home for a PET, part 3: Emerging applications of positron emission tomography imaging in the management of patients with lung cancer
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, Medical School Wing C Room 354, CB 7065, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7065, USA
    Chest 126:1656-66. 2004
  4. ncbi Thoracoscopy using a substernal handport for palpation
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 78:1031-6. 2004
  5. ncbi Seeking a home for a PET, part 2: Defining the appropriate place for positron emission tomography imaging in the staging of patients with suspected lung cancer
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, Department of Surgery, Members of the Multidisciplinary Thoracic Oncology Program, University of North Carolina, Chapel Hill, NC, USA
    Chest 125:2300-8. 2004
  6. ncbi Seeking a home for a PET, part 1: Defining the appropriate place for positron emission tomography imaging in the diagnosis of pulmonary nodules or masses
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, Department of Surgery, University of North Carolina at Chapel Hill, USA
    Chest 125:2294-9. 2004
  7. ncbi Thymic tumors
    Frank C Detterbeck
    Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 77:1860-9. 2004
  8. ncbi Subpleural catheter placement for pain relief after thoracoscopic resection
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, University of North Carolina, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 81:1522-3. 2006
  9. ncbi Lung cancer. Special treatment issues
    Frank C Detterbeck
    Multidisciplinary Thoracic Oncology Program, Division of Cardiothoracic Surgery, University of North Carolina, CB 7605, 108 Burnett Womack Building, Chapel Hill, NC 27599 7065, USA
    Chest 123:244S-258S. 2003
  10. ncbi Changes in the treatment of Pancoast tumors
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 75:1990-7. 2003

Detail Information

Publications53

  1. ncbi Lung cancer. Invasive staging: the guidelines
    Frank C Detterbeck
    Multidisciplinary Thoracic Oncology Program, Division of Cardiothoracic Surgery, University of North Carolina, CB 7065, 108 Burnett Womack Building, Chapel Hill, NC 27599 7065, USA
    Chest 123:167S-175S. 2003
    ..Selection of the optimal approach is best achieved through a multidisciplinary discussion so that all aspects can be weighed appropriately...
  2. ncbi Efficacy of methods of intercostal nerve blockade for pain relief after thoracotomy
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, University of North Carolina, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 80:1550-9. 2005
    ..The other techniques of intercostal blockade do not offer an advantage over narcotics alone...
  3. ncbi Seeking a home for a PET, part 3: Emerging applications of positron emission tomography imaging in the management of patients with lung cancer
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, Medical School Wing C Room 354, CB 7065, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7065, USA
    Chest 126:1656-66. 2004
    ..Further technologic improvements in PET scanners are likely to bring further benefits to the management of patients with lung cancer in the future...
  4. ncbi Thoracoscopy using a substernal handport for palpation
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 78:1031-6. 2004
    ..A substernal handport allows palpation of the lung and thus circumvents one of the major limitations of thoracoscopy...
  5. ncbi Seeking a home for a PET, part 2: Defining the appropriate place for positron emission tomography imaging in the staging of patients with suspected lung cancer
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, Department of Surgery, Members of the Multidisciplinary Thoracic Oncology Program, University of North Carolina, Chapel Hill, NC, USA
    Chest 125:2300-8. 2004
    ..It is unclear and controversial whether a biopsy is needed in patients with clinical stage II lung cancer who have no PET uptake in the mediastinum...
  6. ncbi Seeking a home for a PET, part 1: Defining the appropriate place for positron emission tomography imaging in the diagnosis of pulmonary nodules or masses
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, Department of Surgery, University of North Carolina at Chapel Hill, USA
    Chest 125:2294-9. 2004
    ....
  7. ncbi Thymic tumors
    Frank C Detterbeck
    Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 77:1860-9. 2004
    ..Preoperative chemotherapy appears to increase the rate of complete resection and survival of patients with a stage III or IVa thymoma and should strongly be considered in such cases...
  8. ncbi Subpleural catheter placement for pain relief after thoracoscopic resection
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, University of North Carolina, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 81:1522-3. 2006
    ..This report describes a simple, rapid technique of subpleural catheter placement that lends itself well to thoracoscopic procedures...
  9. ncbi Lung cancer. Special treatment issues
    Frank C Detterbeck
    Multidisciplinary Thoracic Oncology Program, Division of Cardiothoracic Surgery, University of North Carolina, CB 7605, 108 Burnett Womack Building, Chapel Hill, NC 27599 7065, USA
    Chest 123:244S-258S. 2003
    ..Finally, some patients with a solitary focus of metastatic disease in the brain or adrenal gland appear to benefit substantially from resection...
  10. ncbi Changes in the treatment of Pancoast tumors
    Frank C Detterbeck
    Division of Cardiothoracic Surgery, Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 75:1990-7. 2003
    ....
  11. doi Impact of preoperative chemotherapy on pulmonary function tests in resectable early-stage non-small cell lung cancer
    M Patricia Rivera
    Multidisciplinary Thoracic Oncology Group, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7248, USA
    Chest 135:1588-95. 2009
    ....
  12. ncbi Systematic review evaluating the timing of thoracic radiation therapy in combined modality therapy for limited-stage small-cell lung cancer
    Daniel B Fried
    Multidisciplinary Thoracic Oncology Program, Lineberger Comprehensive Cancer Center, Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    J Clin Oncol 22:4837-45. 2004
    ..In addition, we assessed the impact of radiation fractionation and chemotherapeutic regimen on timing...
  13. doi The feasibility of adjuvant carboplatin and docetaxel in patients with curatively resected non-small cell lung cancer
    Thomas E Stinchcombe
    Multidisciplinary Thoracic Oncology Program, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    J Thorac Oncol 3:145-51. 2008
    ..Carboplatin (C) is better tolerated than cisplatin, and carboplatin-based adjuvant therapy may have better chemotherapy compliance...
  14. ncbi Induction and concurrent chemotherapy with high-dose thoracic conformal radiation therapy in unresectable stage IIIA and IIIB non-small-cell lung cancer: a dose-escalation phase I trial
    Mark A Socinski
    Multidisciplinary Thoracic Oncology Program, Lineberger Comprehensive Cancer Center, University of North Carolina, CB 7305, Chapel Hill, NC 27599 7305, USA
    J Clin Oncol 22:4341-50. 2004
    ..Dose escalation using three-dimensional thoracic conformal radiation therapy (TCRT) is one strategy to improve local control and perhaps survival...
  15. ncbi Beliefs among physicians in the diagnostic and therapeutic approach to non-small cell lung cancer
    Thomas E Stinchcombe
    Multidisciplinary Thoracic Oncology Program, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA
    J Thorac Oncol 2:819-26. 2007
    ..Physicians' beliefs and practice patterns may differ significantly from established guidelines. We conducted a survey to assess and compare physician beliefs against the evidence-based guidelines...
  16. ncbi Invasive mediastinal staging of lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition)
    Frank C Detterbeck
    Division of Thoracic Surgery, Department of Surgery, Yale University, 330 Cedar St, FMB 128, New Haven, CT 06520 8062, USA
    Chest 132:202S-220S. 2007
    ..Although imaging studies can provide some guidance, in many situations invasive staging is necessary. Many different complementary techniques are available...
  17. ncbi Helical computed tomography inaccuracy in the detection of pulmonary metastases: can it be improved?
    Alden M Parsons
    Division of Cardiothoracic Surgery, University of North Carolina, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 84:1830-6. 2007
    ..We hypothesized that this may be improved by scan interpretation with adequate clinical history and focused documentation of all pulmonary lesions, and may be influenced by the training of the reader...
  18. ncbi Integration of mediastinal staging techniques for lung cancer
    Frank C Detterbeck
    Division of Thoracic Surgery, Department of Surgery, Yale University, 330 Cedar St, FMB 128, New Haven, CT 06520 8062, USA
    Semin Thorac Cardiovasc Surg 19:217-24. 2007
    ..The goal is to maximize efficiency by enhancing staging accuracy while minimizing the number of tests each patient is subjected to...
  19. doi A model for predicting prolonged length of stay in patients undergoing anatomical lung resection: a National Surgical Quality Improvement Program (NSQIP) database study
    Matthew R DeLuzio
    Department of Surgery, Yale School of Medicine, New Haven, CT, USA
    Interact Cardiovasc Thorac Surg 23:208-15. 2016
    ....
  20. doi Current status of lung cancer screening
    Usman Ahmad
    Division of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06520 8062, USA
    Semin Thorac Cardiovasc Surg 24:27-36. 2012
    ..Many unresolved questions remain that must be addressed to implement computed tomography screening for lung cancer in a thoughtful and responsible way...
  21. ncbi Chromosomal abnormalities in bronchial epithelium from smokers, nonsmokers, and lung cancer patients
    Robbert J C Slebos
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
    Cancer Genet Cytogenet 159:137-42. 2005
    ..These specific alterations were found almost exclusively in patients with a history of tobacco smoking. The results did not indicate that general chromosomal abnormalities are a useful marker for tobacco smoke exposure or cancer risk...
  22. ncbi A phase I study of gemcitabine and docetaxel for advanced stage solid tumors
    Michael E Poole
    Division of Hematology Oncology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
    Cancer Invest 21:350-4. 2003
    ..We conducted a phase I study to determine the maximum tolerated dose of docetaxel in combination with gemcitabine for patients with refractory solid tumors...
  23. doi Defining outcomes of patients with clinical stage I small cell lung cancer upstaged at surgery
    Daniel C Thomas
    Yale University School of Medicine, Department of Surgery, Section of Thoracic Surgery, New Haven, CT, USA
    Lung Cancer 103:75-81. 2017
    ..The existing data regarding the management of upstaged SCLC patients and guidelines for their treatment remains sparse. The primary objective was to describe the impact of pathologic upstaging following surgical resection...
  24. ncbi The differential impact of preoperative comorbidity on perioperative outcomes following thoracoscopic and open lobectomies
    Oliver K Jawitz
    Department of Surgery, Duke University School of Medicine, Durham, NC, USA
    Eur J Cardiothorac Surg . 2016
    ..There is a lack of published data defining the differential impact of preoperative patient comorbidity on outcomes following VATS and OPEN lobectomies, which would be beneficial for procedure selection and clinical decision-making...
  25. doi Evaluation and treatment of stage I and II thymoma
    Frank C Detterbeck
    Thoracic Surgery, Department of Surgery, Yale University, New Haven, Connecticut 06520 8062, USA
    J Thorac Oncol 5:S318-22. 2010
    ..Surgical resection is the mainstay of treatment, and every effort must be made to achieve a complete resection...
  26. ncbi Bronchial margins in lung cancer resection specimens: utility of frozen section and gross evaluation
    Susan J Maygarden
    Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Mod Pathol 17:1080-6. 2004
    ..In lobectomies following wedge resection in which no gross tumor remained, all had negative margins. Salivary gland-type tumors have a high incidence of positive margins, and frozen section is particularly indicated in these tumors...
  27. ncbi Accuracy of helical CT in the detection of pulmonary metastases: is intraoperative palpation still necessary?
    Alden M Parsons
    Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 78:1910-6; discussion 1916-8. 2004
    ..Helical CT detects more nodules than conventional CT, raising the question of whether palpation of the lungs is still necessary if helical CT is used...
  28. ncbi Gemcitabine-based combinations as preoperative therapy in resectable non-small-cell lung cancer
    Mark A Socinski
    Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill 27599 7305, USA
    Clin Lung Cancer 4:S50-5. 2003
    ..Continued evaluation of gemcitabine-containing regimens as preoperative therapy is warranted given their level of activity and tolerability in advanced NSCLC...
  29. doi Standard outcome measures for thymic malignancies
    James Huang
    Division of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, Yale University, New Haven, Connecticut, USA
    J Thorac Oncol 5:2017-23. 2010
    ..Widespread adoption of this baseline will enhance the ability to compare results from different series...
  30. doi Turning gray: the natural history of lung cancer over time
    Frank C Detterbeck
    Department of Surgery, Division of Thoracic Surgery, Yale Cancer Center, Yale University, New Haven, Connecticut, USA
    J Thorac Oncol 3:781-92. 2008
    ..Models of tumor growth, however, are not understood well enough to use the observed doubling time to predict length of survival without treatment...
  31. pmc Assessment of real-time 3D visualization for cardiothoracic diagnostic evaluation and surgery planning
    Bradley M Hemminger
    Department of Radiology and School of Information and Library Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 3360, USA
    J Digit Imaging 18:145-53. 2005
    ..We test whether advanced real-time rendering techniques combined with an effective user interface will allow radiologists and surgeons to improve their performance for cardiothoracic surgery planning and diagnostic evaluation...
  32. ncbi Of buffaloes, horseshoes, and having no connections
    Alden M Parsons
    Department of Surgery, University of North Carolina, Chapel Hill, North Carolina 27599 7065, USA
    Ann Thorac Surg 80:1521-3. 2005
    ..Both hemithoraces were filled by the right lung. The right chest was occupied primarily by the anatomic right lower lobe, and the left chest by the right middle lobe at the apex and the anatomic right upper lobe at the base...
  33. doi Resection of oligometastatic lung cancer to the pancreas may yield a survival benefit in select patients--a systematic review
    Matthew R DeLuzio
    Department of Surgery, Yale New Haven Hospital, New Haven, CT 06520, USA
    Pancreatology 15:456-62. 2015
    ..To conduct a systematic review of the existing literature regarding surgical therapy for oligometastatic lung cancer to the pancreas...
  34. ncbi Fulminant development of mega-aorta due to Takayasu's arteritis: case report and review of the literature
    William P Robinson
    Department of Surgery, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Vascular 13:178-83. 2005
    ..We report an unusual case of Takayasu's arteritis in a 43-year-old man who presented with severe back pain and provide a brief review of the literature...
  35. ncbi Clinical practice. Superior vena cava syndrome with malignant causes
    Lynn D Wilson
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA
    N Engl J Med 356:1862-9. 2007
  36. doi Please lead, but don't mislead
    Frank C Detterbeck
    Chest 134:672; author reply 672-3. 2008
  37. ncbi Positron emission tomographic scanning in the diagnosis and staging of non-small cell lung cancer 2 cm in size or less
    Amir H Khandani
    J Thorac Cardiovasc Surg 132:214-5; author reply 215. 2006
  38. ncbi Clinical value of the WHO classification system of thymoma
    Frank C Detterbeck
    Division of Thoracic Surgery, Yale University, New Haven, Connecticut 06520 8062, USA
    Ann Thorac Surg 81:2328-34. 2006
    ....
  39. ncbi Postoperative radiotherapy for stage II or III non-small-cell lung cancer using the surveillance, epidemiology, and end results database
    Brian E Lally
    Department of Radiation Oncology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157 1030, USA
    J Clin Oncol 24:2998-3006. 2006
    ..To investigate the association between survival and postoperative radiotherapy (PORT) in patients with resected non-small-cell lung cancer (NSCLC)...
  40. ncbi Invited commentary
    Frank C Detterbeck
    Division of Thoracic Surgery, Yale University, FMB 128, New Haven, CT 06520 8062, USA
    Ann Thorac Surg 81:330. 2006
  41. ncbi Does an anecdote substantiate dogma?
    Frank C Detterbeck
    Ann Thorac Surg 81:1182; author reply 1182-3. 2006
  42. ncbi The ABCs of LTX for BAC
    Thomas M Egan
    J Thorac Cardiovasc Surg 125:20-2. 2003
  43. ncbi Evaluation and definitive management of medically inoperable early-stage non-small-cell lung cancer. Part 1: Assessment and conventional radiotherapy
    Roy H Decker
    Yale University School of Medicine New Haven, Connecticut 06520 8040, USA
    Oncology (Williston Park) 20:727-36. 2006
    ..Additionally, emerging evidence suggests that new modalities, such as stereotactic radiosurgery and radiofrequency ablation, may also be potentially curative treatment alternatives. These modalities will be addressed in part 2...
  44. ncbi Life in the real world
    Frank C Detterbeck
    Chest 127:699-701. 2005
  45. ncbi Invited commentary
    Frank C Detterbeck
    Division of Thoracic Surgery, Yale University, FMB 128, 330 Cedar St, New Haven, CT 06520 8062, USA
    Ann Thorac Surg 83:1984-5. 2007
  46. ncbi Lumping, splitting, and sorting
    Frank C Detterbeck
    J Thorac Oncol 2:581-2. 2007
  47. ncbi The risk of death from heart disease in patients with nonsmall cell lung cancer who receive postoperative radiotherapy: analysis of the Surveillance, Epidemiology, and End Results database
    Brian E Lally
    Department of Radiation Oncology, Wake Forest University Health Sciences, Winston Salem, NC 27157 1030, USA
    Cancer 110:911-7. 2007
    ..This study was designed to investigate whether the mortality from heart disease, a manifestation of intercurrent disease after postoperative radiotherapy (PORT), has decreased over time for patients with nonsmall cell lung cancer (NSCLC)...
  48. pmc Evolution and science, progress and change
    Frank C Detterbeck
    Thorax 62:654-5. 2007
  49. ncbi Relearning the lessons of the past: are we making progress?
    Frank C Detterbeck
    Ann Thorac Surg 80:1979-80; author reply 1980-1. 2005
  50. ncbi Airway complications after pulmonary resection
    Emily A Farkas
    Division of Thoracic Surgery, Yale University School of Medicine, 330 Cedar Street, New Haven, CT 06520 8062, USA
    Thorac Surg Clin 16:243-51. 2006
    ....
  51. ncbi Evaluation and definitive management of medically inoperable early stage non-small-cell lung cancer. Part 2: newer treatment modalities
    Roy H Decker
    Yale University School of Medicine, New Haven, Connecticut 06520 8040, USA
    Oncology (Williston Park) 20:899-905; discussion 905-8, 913. 2006
    ..Additionally, emerging evidence suggests that new modalities, such as stereotactic radiosurgery and radiofrequency ablation, may also be potentially curative treatment alternatives. These modalities are addressed in part 2...
  52. doi Neoadjuvant chemotherapy with gemcitabine-containing regimens in patients with early-stage non-small cell lung cancer
    Frank C Detterbeck
    Yale Comprehensive Cancer Center, Yale University, New Haven, Connecticut 06520 8062, USA
    J Thorac Oncol 3:37-45. 2008
    ..Surgical resection alone remains suboptimal for patients with early-stage (I or II) non-small cell lung cancer. Two similar randomized phase II trials were conducted to define an active preoperative regimen in this disease state...
  53. ncbi Smoking is associated with increased telomerase activity in short-term cultures of human bronchial epithelial cells
    Hyeon Woo Yim
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Cancer Lett 246:24-33. 2007
    ..An increase in telomerase activity in normal bronchial epithelium might extend the lifespan of cells at risk for malignant transformation, and thus contribute to lung carcinogenesis...