Geert J De Vries

Summary

Affiliation: University of Massachusetts
Country: USA

Publications

  1. pmc Sex differences in the brain: the relation between structure and function
    Geert J De Vries
    Department of Psychology and Center for Neuroendocrine Studies, Tobin Hall, University of Massachusetts, Amherst, MA 01003 9333, USA
    Horm Behav 55:589-96. 2009
  2. pmc Sexually dimorphic effects of a prenatal immune challenge on social play and vasopressin expression in juvenile rats
    Patrick V Taylor
    Center for Neuroendocrine Studies and Department of Psychology, University of Massachusetts, Amherst, MA, 01003, USA
    Biol Sex Differ 3:15. 2012
  3. ncbi Anatomy and function of extrahypothalamic vasopressin systems in the brain
    G J de Vries
    Center for Neuroendocrine Studies, University of Massachusetts, Amherst 01003 7720, USA
    Prog Brain Res 119:3-20. 1998
  4. ncbi A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits
    Geert J De Vries
    Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Massachusetts 01003 9333, USA
    J Neurosci 22:9005-14. 2002
  5. ncbi Minireview: Sex differences in adult and developing brains: compensation, compensation, compensation
    Geert J De Vries
    Center for Neuroendocrine Studies, Department of Psychology, University of Massachusetts, Amherst, Massachusetts 01003 9333, USA
    Endocrinology 145:1063-8. 2004
  6. pmc Sexual differentiation of vasopressin innervation of the brain: cell death versus phenotypic differentiation
    Geert J De Vries
    Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Massachusetts 01003, USA
    Endocrinology 149:4632-7. 2008
  7. pmc Sex steroids and sex chromosomes at odds?
    Geert J De Vries
    Center for Neuroendocrine Studies, Department of Psychology, Tobin Hall, University of Massachusetts, Amherst, Massachusetts 01003 9333, USA
    Endocrinology 146:3277-9. 2005
  8. pmc Sexual differentiation of central vasopressin and vasotocin systems in vertebrates: different mechanisms, similar endpoints
    G J de Vries
    Center for Neuroendocrine Studies, Department of Psychology, University of Massachusetts, Amherst, 01003, USA
    Neuroscience 138:947-55. 2006
  9. ncbi Neonatal mice possessing an Sry transgene show a masculinized pattern of progesterone receptor expression in the brain independent of sex chromosome status
    Christine K Wagner
    Department of Psychology, and Center for Neuroscience Research, University at Albany State University of New York, 12222, USA
    Endocrinology 145:1046-9. 2004
  10. ncbi Distribution of vasopressin in the forebrain of spotted hyenas
    Greta J Rosen
    Department of Psychology and Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Massachusetts 01003, USA
    J Comp Neurol 498:80-92. 2006

Detail Information

Publications28

  1. pmc Sex differences in the brain: the relation between structure and function
    Geert J De Vries
    Department of Psychology and Center for Neuroendocrine Studies, Tobin Hall, University of Massachusetts, Amherst, MA 01003 9333, USA
    Horm Behav 55:589-96. 2009
    ..This paper makes the case that overstating the magnitude or constancy of sex differences in behavior and too narrowly interpreting the functional consequences of structural differences are significant roadblocks in resolving this issue...
  2. pmc Sexually dimorphic effects of a prenatal immune challenge on social play and vasopressin expression in juvenile rats
    Patrick V Taylor
    Center for Neuroendocrine Studies and Department of Psychology, University of Massachusetts, Amherst, MA, 01003, USA
    Biol Sex Differ 3:15. 2012
    ..We tested whether a prenatal immune challenge interferes with the development of social play and with neural circuits implicated in social behavior...
  3. ncbi Anatomy and function of extrahypothalamic vasopressin systems in the brain
    G J de Vries
    Center for Neuroendocrine Studies, University of Massachusetts, Amherst 01003 7720, USA
    Prog Brain Res 119:3-20. 1998
    ....
  4. ncbi A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits
    Geert J De Vries
    Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Massachusetts 01003 9333, USA
    J Neurosci 22:9005-14. 2002
    ..Moreover, two male groups differing only in the form of their Sry gene showed differences in behavior. The results show that sex chromosome genes contribute directly to the development of a sex difference in the brain...
  5. ncbi Minireview: Sex differences in adult and developing brains: compensation, compensation, compensation
    Geert J De Vries
    Center for Neuroendocrine Studies, Department of Psychology, University of Massachusetts, Amherst, Massachusetts 01003 9333, USA
    Endocrinology 145:1063-8. 2004
    ..Consistent application of this dual-function hypothesis will make the search for the functional significance of sex differences more productive...
  6. pmc Sexual differentiation of vasopressin innervation of the brain: cell death versus phenotypic differentiation
    Geert J De Vries
    Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Massachusetts 01003, USA
    Endocrinology 149:4632-7. 2008
    ..However, even though Bcl-2 overexpression increased VP cell number, it did not affect fiber density. Thus, a compensatory mechanism may control total septal innervation regardless of the number of contributing cells...
  7. pmc Sex steroids and sex chromosomes at odds?
    Geert J De Vries
    Center for Neuroendocrine Studies, Department of Psychology, Tobin Hall, University of Massachusetts, Amherst, Massachusetts 01003 9333, USA
    Endocrinology 146:3277-9. 2005
  8. pmc Sexual differentiation of central vasopressin and vasotocin systems in vertebrates: different mechanisms, similar endpoints
    G J de Vries
    Center for Neuroendocrine Studies, Department of Psychology, University of Massachusetts, Amherst, 01003, USA
    Neuroscience 138:947-55. 2006
    ..Apparently, nature consistently finds a way of maintaining sex differences in vasopressin and vasotocin pathways, suggesting that the function of these differences is important enough that it was conserved during evolution...
  9. ncbi Neonatal mice possessing an Sry transgene show a masculinized pattern of progesterone receptor expression in the brain independent of sex chromosome status
    Christine K Wagner
    Department of Psychology, and Center for Neuroscience Research, University at Albany State University of New York, 12222, USA
    Endocrinology 145:1046-9. 2004
    ....
  10. ncbi Distribution of vasopressin in the forebrain of spotted hyenas
    Greta J Rosen
    Department of Psychology and Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Massachusetts 01003, USA
    J Comp Neurol 498:80-92. 2006
    ..This contrasts with findings in many other vertebrate species, in which VP innervation of the lateral septum is consistently greater in males than in females...
  11. pmc Social control of brain morphology in a eusocial mammal
    Melissa M Holmes
    Center for Neuroendocrine Studies and Department of Psychology, University of Massachusetts, Amherst, MA 01003, USA
    Proc Natl Acad Sci U S A 104:10548-52. 2007
    ..These findings provide evidence that a change in social status triggers considerable neural remodeling and indicate that status, rather than sex, has a predominant role in determining neural structure in this remarkably social mammal...
  12. ncbi Sex differences in progesterone receptor expression: a potential mechanism for estradiol-mediated sexual differentiation
    Princy S Quadros
    Center for Neuroendocrine Studies and Neuroscience and Behavior Program, University of Massachusetts, Amherst 01003, USA
    Endocrinology 143:3727-39. 2002
    ..This suggests that aromatization of T into E is crucial for the sex difference in PR expression in the MPN and AVPv during development...
  13. doi Sex differences in vasopressin and oxytocin innervation of the brain
    Geert J De Vries
    Center for Neuroendocrine Studies, Tobin Hall, University of Massachusetts, Amherst, MA, USA
    Prog Brain Res 170:17-27. 2008
    ....
  14. pmc Sex-specific modulation of juvenile social play by vasopressin
    Alexa H Veenema
    Center for Neuroendocrine Studies, University of Massachusetts, Amherst, MA 01003, USA Neurobiology of Social Behavior Laboratory, Department of Psychology, Boston College, Chestnut Hill, MA, USA Electronic address
    Psychoneuroendocrinology 38:2554-61. 2013
    ..These findings suggest sex- and brain region-specific roles for vasopressin in the regulation of social play behavior in juvenile rats...
  15. pmc Cell death atlas of the postnatal mouse ventral forebrain and hypothalamus: effects of age and sex
    Todd H Ahern
    Center for Behavioral Neuroscience, Department of Psychology, Quinnipiac University, Hamden, Connecticut 06518, USA
    J Comp Neurol 521:2551-69. 2013
    ..These data address large gaps in the developmental literature and suggest interesting region-specific differences in the prevalence and timing of cell death in the hypothalamus and ventral forebrain...
  16. pmc Deletion of Bax eliminates sex differences in the mouse forebrain
    Nancy G Forger
    Department of Psychology and Center for Neuroendocrine Studies, University of Massachusetts, Amherst, MA 01003, USA
    Proc Natl Acad Sci U S A 101:13666-71. 2004
    ....
  17. ncbi Organizational effects of testosterone, estradiol, and dihydrotestosterone on vasopressin mRNA expression in the bed nucleus of the stria terminalis
    Tina M Han
    Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Massachusetts 01003, USA
    J Neurobiol 54:502-10. 2003
    ....
  18. ncbi Progesterone receptors and the sexual differentiation of the medial preoptic nucleus
    Princy S Quadros
    Center for Neuroendocrine Studies, Neuroscience and Behavior Program and Department of Psychology, Tobin Hall, Box 37720, University of Massachusetts, Amherst, Massachusetts 01003, USA
    J Neurobiol 51:24-32. 2002
    ..These results, taken together with the expression of PR in the MPNc, suggest that PR may influence the sexual differentiation of the MPNc volume...
  19. pmc Epigenetic control of sexual differentiation of the bed nucleus of the stria terminalis
    Elaine K Murray
    Department of Psychology and Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Massachusetts 01003, USA
    Endocrinology 150:4241-7. 2009
    ..These findings suggest that a disruption in histone deacetylation may lead to long-term alterations in gene expression that block the masculinizing actions of testosterone in the BNSTp...
  20. ncbi Distribution of vasopressin in the brain of the eusocial naked mole-rat
    Greta J Rosen
    Department of Psychology and Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Massachusetts 01003, USA
    J Comp Neurol 500:1093-105. 2007
    ..Future studies on the function of VP in these areas are needed to determine how the atypical distribution of VP immunoreactivity relates to eusociality and the unusual physiology of naked mole-rats...
  21. pmc Cell death and sexual differentiation of behavior: worms, flies, and mammals
    Nancy G Forger
    Department of Psychology and Center for Neuroendocrine Studies, University of Massachusetts, Amherst, MA 01003, USA
    Curr Opin Neurobiol 20:776-83. 2010
    ..Advanced genetic strategies are also addressing this question in worms and flies, and may soon be applicable to vertebrates...
  22. pmc Role of pregnancy and parturition in induction of maternal behavior in prairie voles (Microtus ochrogaster)
    Unja L Hayes
    Department of Psychology and Center for Neuroendocrine Studies, University of Massachusetts, Tobin Hall, Amherst, MA 01003, USA
    Horm Behav 51:265-72. 2007
    ..This suggests that events closely related to parturition are crucial for full development of maternal behavior in female prairie voles...
  23. pmc Vasopressin innervation of the mouse (Mus musculus) brain and spinal cord
    Benjamin D Rood
    Center for Neuroendocrine Studies and Department of Psychology and Neuroscience, University of Massachusetts, Amherst, Massachusetts 01003, USA
    J Comp Neurol 519:2434-74. 2011
    ..Our data also highlight the robust nature of AVP innervation in specific regulatory nuclei, such as the ventral tegmental area and dorsal raphe nucleus among others, that are implicated in the regulation of many behaviors...
  24. doi Site of origin of and sex differences in the vasopressin innervation of the mouse (Mus musculus) brain
    Benjamin D Rood
    Department of Anesthesiology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    J Comp Neurol 521:2321-58. 2013
    ....
  25. ncbi Parental responsiveness is feminized after neonatal castration in virgin male prairie voles, but is not masculinized by perinatal testosterone in virgin females
    Joseph S Lonstein
    Center for Neuroendocrine Studies, University of Massachusetts, Tobin Hall, Amherst, Massachusetts 01003, USA
    Horm Behav 41:80-7. 2002
    ..Therefore, although postnatal testicular hormones are necessary for high parental responsiveness in males, the behavior of females is not influenced by perinatal exposure to testosterone...
  26. pmc Unexpected effects of perinatal gonadal hormone manipulations on sexual differentiation of the extrahypothalamic arginine-vasopressin system in prairie voles
    Joseph S Lonstein
    Program in Neuroscience and Department of Psychology, Michigan State University, East Lansing, Michigan 48823, USA
    Endocrinology 146:1559-67. 2005
    ..Such insensitivity is atypical for a sexually dimorphic neural system in a rodent and may reflect the unusual effects of hormones on sexual differentiation of some behaviors in prairie voles...
  27. ncbi Sexual differentiation of the bed nucleus of the stria terminalis in humans may extend into adulthood
    Wilson C J Chung
    Netherlands Institute for Brain Research, 1105 AZ Amsterdam, The Netherlands
    J Neurosci 22:1027-33. 2002
    ..The unexpectedly late sexual differentiation of the BSTc is discussed in relation to sex differences in developmental, adolescent, and adult gonadal steroid levels...
  28. ncbi Two perspectives on the origin of sex differences in the brain
    Arthur P Arnold
    Department of Physiological Science, and Laboratory of Neuroendocrinology of the Brain Research Institute, University of California, Los Angeles, California 90095, USA
    Ann N Y Acad Sci 1007:176-88. 2003
    ..This paper reviews the evidence that genetic sex of brain cells influences their sexual phenotype, and critically discusses the relative advantages of various experimental approaches to study this effect...