Timothy J Davern
Affiliation: University of California
- Molecular therapeutics of liver diseaseT J Davern
Division of Gastroenterology, University of California San Francisco, San Francisco, California, USA
Clin Liver Dis 5:381-414, vi. 2001..Eventually, these obstacles will be overcome, and molecular therapeutics of liver disease will become a clinical reality. As a result, the new millennium will be a very interesting time to practice hepatology...
- Leukotriene antagonistsTimothy J Davern
University of California, Division of Gastroenterology, 513 Parnassus Avenue, Room S 357, San Francisco 94143, CA, USA
Clin Liver Dis 7:501-12, viii. 2003..It is in context of this heightened awareness of hepatotoxicity, particularly associated with new high profile drugs, that the authors reviews the published data regarding liver injury related to a novel group of asthma drugs...
- Liver transplantation for hepatocellular carcinoma: analysis of survival according to the intention-to-treat principle and dropout from the waiting listFrancis Y Yao
Department of Medicine, Division of Gastroenterology, University of California, San Francisco, CA 94143 0538, USA
Liver Transpl 8:873-83. 2002..Our results support recent changes in the scheme of organ allocation aimed at reducing the dropout rate and improving outcome for patients with HCC awaiting OLT...
- Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: an intention-to-treat analysisFrancis Y Yao
Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
Hepatology 48:819-27. 2008..2% and 92.1%, respectively. No patient had HCC recurrence after a median posttransplantation follow-up of 25 months. The only factor predicting treatment failure was pretreatment alpha-fetoprotein >1,000 ng/mL...
- A follow-up analysis of the pattern and predictors of dropout from the waiting list for liver transplantation in patients with hepatocellular carcinoma: implications for the current organ allocation policyFrancis Y Yao
Department of Medicine, Division of Gastroenterology, University of California, San Francisco 94143, USA
Liver Transpl 9:684-92. 2003..004). In conclusion, the low dropout rate in the first 6 months and the differing dropout risks based on tumor characteristics support further refinements in the HCC-adjusted MELD organ allocation scheme...
- Measurement of serum acetaminophen-protein adducts in patients with acute liver failureTimothy J Davern
University of California at San Francisco, San Francisco, California, USA corrected
Gastroenterology 130:687-94. 2006..Measurement of serum adducts might improve diagnostic accuracy in acute liver failure (ALF) patients...
- A prospective study on downstaging of hepatocellular carcinoma prior to liver transplantationFrancis Y Yao
Department of Medicine, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143 0538, USA
Liver Transpl 11:1505-14. 2005..3 and 81.8% at 1 and 2 yr, respectively. In conclusion, successful tumor downstaging can be achieved in the majority of carefully selected patients, but longer follow-up is needed to further access the risk of HCC recurrence after OLT...
- Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective studyAnne M Larson
Department of Internal Medicine, Division of Gastroenterology, University of Washington Medical Center, Seattle, 98195, USA
Hepatology 42:1364-72. 2005..Susceptible patients have concomitant depression, chronic pain, alcohol or narcotic use, and/or take several preparations simultaneously. Education of patients, physicians, and pharmacies to limit high-risk use settings is recommended...
- Eosinophilic hepatitis caused by lamotrigineOren K Fix
Division of Gastroenterology, University of California, San Francisco, San Francisco, California, USA
Clin Gastroenterol Hepatol 4:xxvi. 2006
- Detection of acetaminophen protein adducts in children with acute liver failure of indeterminate causeLaura P James
Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children s Hospital Research Institute, Little Rock, Arkansas, USA
Pediatrics 118:e676-81. 2006..The objective of this study was to use a new assay for the detection of acetaminophen cysteine protein adducts in children with acute liver failure to determine the role of acetaminophen toxicity in acute liver failure of unknown cause...
- Results of a prospective study of acute liver failure at 17 tertiary care centers in the United StatesGeorge Ostapowicz
Department of Medicine, Gold Coast Hospital, 108 Nerang Street, Southport, QLD 4215, Australia
Ann Intern Med 137:947-54. 2002..Because acute liver failure is rare, related data have been sparse. Studies have suggested that viral hepatitis is the most common underlying cause of this condition...
- Predicting prognosis in acute liver failure: Ammonia and the risk of cerebral edemaTimothy J Davern
Hepatology 46:1679-81. 2007
- False positive acetaminophen concentrations in patients with liver injuryJulie Polson
Department of Internal Medicine, University of Texas Southwestern Medical Center, 5959 Harry Hines Boulevard, Dallas, TX 75390, USA
Clin Chim Acta 391:24-30. 2008..However, recent case reports have suggested that acetaminophen concentrations may be falsely increased in the presence of hyperbilirubinemia...
- Complications and use of intracranial pressure monitoring in patients with acute liver failure and severe encephalopathyJavier Vaquero
Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA
Liver Transpl 11:1581-9. 2005..In view of the high 30-day survival rate after LT, future studies of the impact of intracranial hypertension should also focus on long-term neurological recovery from ALF...
- Acetaminophen hepatotoxicityTimothy J Davern
Hepatology 40:1021-2; discussion 1022. 2004
- Viral hepatitis-related acute liver failureFrank Vinholt Schiødt
Department of Gastroenterology, Rigshospitalet, Copenhagen, Denmark
Am J Gastroenterol 98:448-53. 2003..We aimed to determine the incidence of viral hepatitis-related ALF and to compare the outcome and clinical and biochemical variables in patients with hepatitis A and B...
- Screening for Wilson disease in acute liver failure: a comparison of currently available diagnostic testsJessica D Korman
Montefiore Medical Center, Bronx, NY, USA
Hepatology 48:1167-74. 2008..In addition, an AST:ALT ratio >2.2 yielded a sensitivity of 94%, a specificity of 86%, and a likelihood ratio of 7 for diagnosing fulminant WD. Combining the tests provided a diagnostic sensitivity and specificity of 100%...
- NOVEL METHODS OF GENE THERAPY FOR LIVER DISEASETimothy Davern; Fiscal Year: 2002....