- Systemic chemotherapy induces microsatellite instability in the peripheral blood mononuclear cells of breast cancer patientsFernando L A Fonseca
ABC Foundation School of Medicine, Hematology and Oncology, Santo Andre, Sao Paulo, Brazil
Breast Cancer Res 7:R28-32. 2005..We conducted the present study to evaluate whether systemic chemotherapy could produce microsatellite instability (MSI) in the peripheral blood mononuclear cell fraction of breast cancer patients...
- Negative results in cancer clinical trials--equivalence or poor accrual?Luciano J M Costa
University of Colorado Health Science Center, Room L18 8122, 12801 E 17th Avenue, Aurora, CO 80010, USA
Control Clin Trials 25:525-33. 2004..Comparisons involving new drugs are specially affected by this problem. Authors, editors and readers must be more rigorous regarding adequate assumptions of equivalence...