R L Cooper

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. ncbi request reprint Bioelectric field potentials of the ventilatory muscles in the crayfish
    Zh P Shuranova
    Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia
    Comp Biochem Physiol A Mol Integr Physiol 134:461-9. 2003
  2. pmc Recent advances in basic neurosciences and brain disease: from synapses to behavior
    Guo Qiang Bi
    Department of Neurobiology, University of Pittsburgh, Pittsburgh, USA
    Mol Pain 2:38. 2006
  3. ncbi request reprint Intrinsic differences in sensitivity to 5-HT between high- and low-output terminals innervating the same target
    Robin L Cooper
    Department of Biology, University of Kentucky, Lexington, KY 40506 0225, USA
    Neurosci Res 45:163-72. 2003
  4. ncbi request reprint The effects of serotonin and ecdysone on primary sensory neurons in crayfish
    Robin L Cooper
    Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington, Kentucky 40506 0225, USA
    Microsc Res Tech 60:336-45. 2003
  5. ncbi request reprint Development of sensory processes during limb regeneration in adult crayfish
    R L Cooper
    Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington, KY 40506 0225, USA
    J Exp Biol 201:1745-52. 1998
  6. ncbi request reprint Altered responsiveness to 5-HT at the crayfish neuromuscular junction due to chronic p-CPA and m-CPP treatment
    R L Cooper
    Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington, KY 40506 0225, USA
    Brain Res 916:143-51. 2001
  7. ncbi request reprint Dopaminergic modulation of motor neuron activity and neuromuscular function in Drosophila melanogaster
    R L Cooper
    Nerve Muscle Group, Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington 40506 0225, USA
    Comp Biochem Physiol B Biochem Mol Biol 122:199-210. 1999
  8. ncbi request reprint Quantification of responses from proprioceptive neurons in the limbs of the crab, Cancer magister
    R L Cooper
    Nerve Muscle Group, Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington, Kentucky 40506, USA
    J Exp Zool 284:629-36. 1999
  9. doi request reprint The regulation and packaging of synaptic vesicles as related to recruitment within glutamatergic synapses
    W H Wu
    Department of Biology and Center for Muscle Biology, University of Kentucky, Lexington, KY 40506 0225, United States
    Neuroscience 225:185-98. 2012
  10. ncbi request reprint Alterations in development, behavior, and physiology in Drosophila larva that have reduced ecdysone production
    H Li
    School of Biological Sciences, University of Kentucky, Lexington 40506 0225, USA
    J Neurophysiol 85:98-104. 2001

Collaborators

  • H Li
  • L Hsu
  • S Kim
  • S B Moffett
  • A R Tilden
  • Nae J Dun
  • Wendi Neckameyer
  • Harold Atwood
  • J L Winslow
  • Sameera Dasari
  • Kert Viele
  • A F M Johnstone
  • G M Sparks
  • Eugen Brailoiu
  • Mark Lancaster
  • Wen hui Wu
  • W H Wu
  • Bin Xing
  • Douglas A Harrison
  • S M Bierbower
  • J Y Lee
  • Mohati Desai-Shah
  • K Viele
  • S Logsdon
  • Andrew F M Johnstone
  • Guo Qiang Bi
  • Amanda J Dropic
  • Nicolas H Badre
  • Maurice Pierre Pagé
  • Zh P Shuranova
  • Garrett M Sparks
  • Ryan Ball
  • Jeffery R Strawn
  • Jami N Tabor
  • Heidi Schapker
  • B Griffis
  • S Kellie
  • W Y Chung
  • D Bhatt
  • A Clay Turner
  • Zhou Feng Chen
  • Graham L Collingridge
  • Bong Kiun Kaang
  • John F MacDonald
  • Wen Biao Gan
  • Zao C Xu
  • Shao Jun Tang
  • Melanie A Woodin
  • Alaa El-Husseini
  • Vadim Bolshakov
  • Zhengping Jia
  • Koichi Iwata
  • Yuanxiang Tao
  • Jianguo Gu
  • Mei Zhen
  • Yu Tian Wang
  • Mikito Kawamata
  • Jens R Coorssen
  • Xia Zhang
  • Vasco Galhardo
  • Karim Nader
  • Michael W Salter
  • Guojun Bu
  • Tatsuro Kohno
  • Eric Klann
  • Catherine M Cahill
  • John Isaac
  • Uhtaek Oh
  • Peter V Nguyen
  • Ke Ren
  • Xiao Jiang Li
  • Zhen Yan
  • Shuzo Sugita
  • John C Roder
  • Min Li
  • Kazuhide Inoue
  • Weihong Song
  • Min Zhuo
  • Megumu Yoshimura
  • Satoshi Kida
  • Ming Xu
  • Newton Woo
  • A Ashleigh Long
  • M Elisabeth Martin
  • S Dasari
  • Yu M Burmistrov
  • Arnold J Stromberg
  • G Cristina Brailoiu
  • Joseph Shearer
  • Jami Tabor

Detail Information

Publications43

  1. ncbi request reprint Bioelectric field potentials of the ventilatory muscles in the crayfish
    Zh P Shuranova
    Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia
    Comp Biochem Physiol A Mol Integr Physiol 134:461-9. 2003
    ....
  2. pmc Recent advances in basic neurosciences and brain disease: from synapses to behavior
    Guo Qiang Bi
    Department of Neurobiology, University of Pittsburgh, Pittsburgh, USA
    Mol Pain 2:38. 2006
    ..The second international meeting on Neurons and Brain Disease will be held in Toronto (August 29-31, 2007)...
  3. ncbi request reprint Intrinsic differences in sensitivity to 5-HT between high- and low-output terminals innervating the same target
    Robin L Cooper
    Department of Biology, University of Kentucky, Lexington, KY 40506 0225, USA
    Neurosci Res 45:163-72. 2003
    ..The results provide new details concerning differential modulation of low- and high-output synapses present on the same target tissue...
  4. ncbi request reprint The effects of serotonin and ecdysone on primary sensory neurons in crayfish
    Robin L Cooper
    Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington, Kentucky 40506 0225, USA
    Microsc Res Tech 60:336-45. 2003
    ..This outcome indicates that mixtures of these endogenous neuromodulators, at various levels, are more important in alternating behavior than the absolute level of any one of them introduced alone...
  5. ncbi request reprint Development of sensory processes during limb regeneration in adult crayfish
    R L Cooper
    Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington, KY 40506 0225, USA
    J Exp Biol 201:1745-52. 1998
    ..These results also indicate a progressive advance of growth cones, presumably sensory in origin, towards the neuropil within the ganglion over time...
  6. ncbi request reprint Altered responsiveness to 5-HT at the crayfish neuromuscular junction due to chronic p-CPA and m-CPP treatment
    R L Cooper
    Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington, KY 40506 0225, USA
    Brain Res 916:143-51. 2001
    ..However, acute applications of p-CPA and m-CPP, followed by extensive saline washing, did not reveal any altered receptivity to 5-HT application...
  7. ncbi request reprint Dopaminergic modulation of motor neuron activity and neuromuscular function in Drosophila melanogaster
    R L Cooper
    Nerve Muscle Group, Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington 40506 0225, USA
    Comp Biochem Physiol B Biochem Mol Biol 122:199-210. 1999
    ..The effects are presynaptic in causing a reduction in the number of vesicles that are stimulated to be released due to neural activity...
  8. ncbi request reprint Quantification of responses from proprioceptive neurons in the limbs of the crab, Cancer magister
    R L Cooper
    Nerve Muscle Group, Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington, Kentucky 40506, USA
    J Exp Zool 284:629-36. 1999
    ..We found some cells to have a high eta(2) and to be consistent in their activity while other cells had a high degree of variability with low eta(2) values. J. Exp. Zool. 284:629-636, 1999...
  9. doi request reprint The regulation and packaging of synaptic vesicles as related to recruitment within glutamatergic synapses
    W H Wu
    Department of Biology and Center for Muscle Biology, University of Kentucky, Lexington, KY 40506 0225, United States
    Neuroscience 225:185-98. 2012
    ..After low frequency depression and/or exposure to bafilomycin A1 a burst of higher frequency (10 Hz) can recruit vesicles from the RP to the RRP...
  10. ncbi request reprint Alterations in development, behavior, and physiology in Drosophila larva that have reduced ecdysone production
    H Li
    School of Biological Sciences, University of Kentucky, Lexington 40506 0225, USA
    J Neurophysiol 85:98-104. 2001
    ..Structurally the number of varicosities and the terminal length showed significant differences between ecd(1)/ecd(1) and the wild-type ecd(1)/TM6B genotype in the late third instars...
  11. ncbi request reprint Effects of the ecdysoneless mutant on synaptic efficacy and structure at the neuromuscular junction in Drosophila larvae during normal and prolonged development
    H Li
    101 T H Morgan School of Biological Sciences, University of Kentucky, Lexington, KY 40506 0225, USA
    Neuroscience 106:193-200. 2001
    ..This study demonstrates ecdysone's role in modifying nerve terminal development and neuromuscular junction function...
  12. ncbi request reprint Regulation of synaptic vesicles pools within motor nerve terminals during short-term facilitation and neuromodulation
    S Logsdon
    Dept of Biology, Univ of Kentucky, Lexington, KY 40506 0225, USA
    J Appl Physiol 100:662-71. 2006
    ..This suggests at least two separate kinetic and distinct regulatory paths for vesicle recycling within the presynaptic nerve terminal...
  13. doi request reprint Physiological separation of vesicle pools in low- and high-output nerve terminals
    Wen hui Wu
    Department of Biology and Center of Muscle Biology, University of Kentucky, Lexington, KY 40506 0225, United States
    Neurosci Res 75:275-82. 2013
    ..The vesicle pools are physiologically differentiated between phasic and tonic output terminals...
  14. ncbi request reprint Actions of MDMA at glutamatergic neuromuscular junctions
    G M Sparks
    Department of Biology, University of Kentucky, Lexington, KY 40506 0225, USA
    Neurosci Res 48:431-8. 2004
    ....
  15. pmc Structure/function assessment of synapses at motor nerve terminals
    A F M Johnstone
    Department of Biology, University of Kentucky, Lexington, Kentucky 40506 0225, USA
    Synapse 65:287-99. 2011
    ..In this study, we could not identify a quantal signature for the conditions utilized...
  16. ncbi request reprint Development of Drosophila larval neuromuscular junctions: maintaining synaptic strength
    H Li
    Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington 40506 0225, USA
    Neuroscience 115:505-13. 2002
    ....
  17. ncbi request reprint Assessing accurate sizes of synaptic vesicles in nerve terminals
    S Kim
    Department of Mathematics, University of Kentucky, Lexington, KY 40506 0027, USA
    Brain Res 877:209-17. 2000
    ..A FORTRAN program is provided...
  18. doi request reprint Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction
    J Y Lee
    Department of Biology, University of Kentucky, Lexington, KY, USA 40506 0225, USA
    Comp Biochem Physiol C Toxicol Pharmacol 150:546-57. 2009
    ..There does not appear to be presynaptic auto-regulation via a kainate receptor subtype or a metabotropic auto-receptor. This study aids in furthering the pharmokinetic profiling and specificity of the receptor subtypes...
  19. ncbi request reprint Muscle phenotype remains unaltered after limb autotomy and unloading
    B Griffis
    Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington, KY 40506-0225, USA
    J Exp Zool 289:10-22. 2001
    ..This is likely due either to the intact innervation and continued activation of the levator during atrophy or to the maintenance of passive tension on the muscle. J. Exp. Zool. 289:10-22, 2001...
  20. ncbi request reprint 5-HT offsets homeostasis of synaptic transmission during short-term facilitation
    G M Sparks
    Department of Biology, University of Kentucky, Lexington, KY 40506 0225, USA
    J Appl Physiol 96:1681-90. 2004
    ..We propose that 5-HT and electrically induced recruitment of vesicles from a reserve pool to the RRP may share similar recruitment mechanisms...
  21. ncbi request reprint Presynaptic mechanism of action induced by 5-HT in nerve terminals: possible involvement of ryanodine and IP3 sensitive 2+ stores
    Amanda J Dropic
    Department of Biology, University of Kentucky, Lexington, KY 40506 0225, USA
    Comp Biochem Physiol A Mol Integr Physiol 142:355-61. 2005
    ..Thus, it is likely 5-HT's response is due to activation of intracellular pathways, which subsequently release Ca2+ from internal stores...
  22. ncbi request reprint Automated classification of evoked quantal events
    Mark Lancaster
    Department of Statistics, University of Kentucky, Lexington, KY 40506 0027, United States
    J Neurosci Methods 159:325-36. 2007
    ..In our experience, the software reduces the time required to perform these analyses from hours to minutes...
  23. ncbi request reprint The effects of ethanol on pre-synaptic components of synaptic transmission in a model glutamatergic synapse: the crayfish neuromuscular junction
    Jeffery R Strawn
    101 T H Morgan School of Biological Sciences, University of Kentucky, Lexington, KY 40506 0225, USA
    Comp Biochem Physiol C Toxicol Pharmacol 131:395-404. 2002
    ..Thus, the observed decrease in synaptic strength is at least partially attributable to a pre-synaptic alteration, specifically the release of fewer vesicles...
  24. ncbi request reprint Novelty stress and reproductive state alters responsiveness to sensory stimuli and 5-HT neuromodulation in crayfish
    Maurice Pierre Pagé
    Department of Biology, University of Kentucky, Rose St, Lexington, 40506 0225, USA
    Comp Biochem Physiol A Mol Integr Physiol 139:149-58. 2004
    ..Gravid females show no tail flipping behavior upon telson stimulation...
  25. ncbi request reprint Effects of m-CPP in altering neuronal function: blocking depolarization in invertebrate motor and sensory neurons but exciting rat dorsal horn neurons
    Garrett M Sparks
    Department of Biology, University of Kentucky, Lexington, KY 40506 0225, USA
    Brain Res 969:14-26. 2003
    ..In the rat spinal cord, m-CPP enhances the occurrence of spontaneous excitatory postsynaptic potentials with no alteration in evoked currents...
  26. ncbi request reprint Physiologically identified 5-HT2-like receptors at the crayfish neuromuscular junction
    Jami N Tabor
    Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington, KY 40506 0225, USA
    Brain Res 932:91-8. 2002
    ..By knowing the types of 5-HT receptors present on the presynaptic motor nerve terminals in this model synaptic preparation, a better understanding of the mechanisms of action of 5-HT on vesicular release will be forthcoming...
  27. ncbi request reprint Influence of PCPA and MDMA (ecstasy) on physiology, development and behavior in Drosophila melanogaster
    Sameera Dasari
    Department of Biology, 675 Rose Street, University of Kentucky, Lexington, KY 40506 0225, USA
    Eur J Neurosci 26:424-38. 2007
    ..The actions of acute MDMA exposure suggest a 5-HT agonist action or possible dumping of 5-HT from neurons...
  28. ncbi request reprint Self-modeling structure of evoked postsynaptic potentials
    Kert Viele
    Department of Statistics, University of Kentucky, Lexington, Kentucky 40506 0027, USA
    Synapse 60:32-44. 2006
    ..Computer code in R is available on the internet to perform the analysis...
  29. doi request reprint Different mechanisms of Ca2+ regulation that influence synaptic transmission: comparison between crayfish and Drosophila neuromuscular junctions
    Mohati Desai-Shah
    Department of Biology, University of Kentucky, Lexington, Kentucky 40506 0225, USA
    Synapse 63:1100-21. 2009
    ..Results in crayfish NMJ were more consistent with expected results as compared to the Drosophila NMJ. It is predicated that different mechanisms are used for regulating the [Ca(2+)](i) in high and low output synaptic terminals...
  30. ncbi request reprint Estimating the number of release sites and probability of firing within the nerve terminal by statistical analysis of synaptic charge
    Kert Viele
    Department of Statistics, University of Kentucky, Lexington, Kentucky 40506 0027, USA
    Synapse 47:15-25. 2003
    ..Our results indicate that as the stimulation frequency increases, new sites are recruited (thus increasing n) and the probability of release (p) increases...
  31. ncbi request reprint Long-term in vitro maintenance of neuromuscular junction activity of Drosophila larvae
    Ryan Ball
    Department of Biology, University of Kentucky, 101 Rose Street, 40506 0225, Lexington, KY, USA
    Comp Biochem Physiol A Mol Integr Physiol 134:247-55. 2003
    ..These results demonstrate the possibility for chronic studies of developmental regulation in culture, which in some cases are impractical in the whole animal...
  32. ncbi request reprint Developmental consequences of neuromuscular junctions with reduced presynaptic calcium channel function
    Bin Xing
    Department of Biology, University of Kentucky, Lexington, KY 40506 0225, USA
    Synapse 57:132-47. 2005
    ....
  33. ncbi request reprint The physiological and behavioral effects of carbon dioxide on Drosophila melanogaster larvae
    Nicolas H Badre
    Department of Biology, University of Kentucky, Lexington, KY 40506 0225, USA
    Comp Biochem Physiol A Mol Integr Physiol 140:363-76. 2005
    ..melanogaster preparation are similar in function to ionotropic glutamate receptors in vertebrates which could account for the observational phenomena of CO2 not yet explained mechanistically in vertebrates...
  34. ncbi request reprint Modulatory effects of melatonin on behavior, hemolymph metabolites, and neurotransmitter release in crayfish
    Andrea R Tilden
    Department of Biology, Colby College, 5720 Mayflower Hill, Waterville, ME 04901, USA
    Brain Res 992:252-62. 2003
    ..Behavioral and physiological effects may be mediated by modulation of central pathways, enhanced at the peripheral level via neuromodulation of the NMJ...
  35. doi request reprint The effects of acute carbon dioxide on behavior and physiology in Procambarus clarkii
    S M Bierbower
    Department of Biology, University of Kentucky, Lexington, Kentucky, USA
    J Exp Zool A Ecol Genet Physiol 313:484-97. 2010
    ..Additionally, the autonomic bioindex of heart and ventilatory rates showed a complete cessation with high acute exposure within in the same time period for unresponsiveness to mechanosensory stimulation...
  36. ncbi request reprint Alterations in habituation of the tail flip response in epigean and troglobitic crayfish
    S Kellie
    School of Biological Sciences, University of Kentucky, Lexington, KY 40506-0225, USA
    J Exp Zool 290:163-76. 2001
    ..Differences between the two species indicate that size may not be the sole contributing factor to account for tail flip behaviors. J. Exp. Zool. 290:163-176, 2001...
  37. ncbi request reprint Direct innervation of the Drosophila melanogaster larval aorta
    Andrew F M Johnstone
    Department of Biology, University of Kentucky, 675 Rose Street, University of Kentucky, Lexington, KY 40506 0225, USA
    Brain Res 1083:159-63. 2006
    ..Transmission electron microscopy reveals the direct innervation in the aortic tissue. Thus, developmental and regulatory questions in this genetic model can now be addressed in relation to heart development and neural control...
  38. ncbi request reprint Characterization of development, behavior and neuromuscular physiology in the phorid fly, Megaselia scalaris
    Douglas A Harrison
    Department of Biology, University of Kentucky, Lexington, KY 40506 0225, USA
    Comp Biochem Physiol A Mol Integr Physiol 136:427-39. 2003
    ..We conclude that there may be differences in synaptic structure of the nerve terminals that could account for the different electrophysiological behaviors...
  39. ncbi request reprint Modulation of sensory-CNS-motor circuits by serotonin, octopamine, and dopamine in semi-intact Drosophila larva
    Sameera Dasari
    Department of Biology, University of Kentucky, 101 Rose Street, Lexington, KY 40506 0225, USA
    Neurosci Res 48:221-7. 2004
    ....
  40. ncbi request reprint Direct influence of serotonin on the larval heart of Drosophila melanogaster
    Sameera Dasari
    Department of Biology, University of Kentucky, 675 Rose Street, Lexington, KY 40506 0225, USA
    J Comp Physiol B 176:349-57. 2006
    ..In summary, direct application of 5-HT to the larval heart had significant effects in a dose-dependent manner while MDMA had no effect...
  41. ncbi request reprint Heart and ventilatory measures in crayfish during environmental disturbances and social interactions
    Heidi Schapker
    Thomas Hunt Morgan School of Biological Sciences, University of Kentucky, Lexington, KY 40506 0225, USA
    Comp Biochem Physiol A Mol Integr Physiol 131:397-407. 2002
    ..Since behavioral observations do not allow an internal status to be readily assessed, we suggest that HR and VR may serve as a useful bioindex in crustaceans to their internal drive or possibly an awareness level to environmental cues...
  42. pmc Sphingosine 1-phosphate enhances spontaneous transmitter release at the frog neuromuscular junction
    Eugen Brailoiu
    Department of Pharmacology, James H Quillen College of Medicine, East Tennessee State University, PO Box 70577, Johnson City 37614, USA
    Br J Pharmacol 136:1093-7. 2002
    ..The result provides the first evidence that S1-P acting intracellularly but not extracellularly enhances spontaneous transmitter release at the frog neuromuscular junction...
  43. ncbi request reprint Intracellular ionic concentration by calibration from fluorescence indicator emission spectra, its relationship to the K(d), F(min), F(max) formula, and use with Na-Green for presynaptic sodium
    James L Winslow
    Physiology Department, University of Toronto, Toronto, ON, Canada M5S 1A8
    J Neurosci Methods 118:163-75. 2002
    ..The terminals of crayfish motor axon have surface area to volume ratio which is 7700 times larger than for squid. Thus, in comparison to squid, crayfish terminals exhibit a larger change in [Na(+)](i) during equivalent AP activity...