Affiliation: University of California
- cAMP-dependent protein kinase types I and II differentially regulate cAMP response element-mediated gene expression: implications for neuronal responses to ethanolAnastasia Constantinescu
Ernest Gallo Clinic and Research Center, Department of Neurology, University of California at San Francisco, Emeryville, California 94608, USA
J Biol Chem 277:18810-6. 2002..By contrast, type I PKA is activated in the cytoplasm, turning on a downstream pathway that activates other transcription cofactors that interact with phosphorylated CREB to induce gene transcription...
- cAMP-dependent protein kinase type I regulates ethanol-induced cAMP response element-mediated gene expression via activation of CREB-binding protein and inhibition of MAPKAnastasia Constantinescu
Ernest Gallo Clinic and Research Center, Department of Neurology, University of California, San Francisco, Emeryville, CA 94608, USA
J Biol Chem 279:43321-9. 2004..Under these conditions p90RSK is no longer bound to CBP, thereby promoting CBP-dependent CREB-mediated gene expression...