Clare C Constantine

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosis
    Clare C Constantine
    The Centre for Molecular, Environmental, Genetic and Analytic MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    BMC Med Genet 9:18. 2008
  2. pmc HFE Cys282Tyr homozygotes with serum ferritin concentrations below 1000 microg/L are at low risk of hemochromatosis
    Katrina J Allen
    Murdoch Childrens Research Institute, Melbourne, Australia
    Hepatology 52:925-33. 2010
  3. pmc HFE C282Y homozygotes are at increased risk of breast and colorectal cancer
    Nicholas J Osborne
    Gut and Liver, Murdoch Childrens Research Institute, Melbourne, Vic, Australia
    Hepatology 51:1311-8. 2010
  4. pmc A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis
    Clare C Constantine
    Centre for MEGA Epidemiology, School of Population Health, University of Melbourne, Carlton, Victoria, Australia
    Br J Haematol 147:140-9. 2009
  5. doi request reprint The natural history of serum iron indices for HFE C282Y homozygosity associated with hereditary hemochromatosis
    Lyle C Gurrin
    Centre for MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    Gastroenterology 135:1945-52. 2008
  6. doi request reprint A comparison of self-reported and record-linked blood donation history in an Australian cohort
    Nadine A Bertalli
    Centre for MEGA Epidemiology, School of Population Health, The University of Melbourne, Australia
    Transfusion 51:2189-98. 2011
  7. doi request reprint Iron-overload-related disease in HFE hereditary hemochromatosis
    Katrina J Allen
    Murdoch Children s Research Institute, University of Melbourne, Melbourne, Australia
    N Engl J Med 358:221-30. 2008
  8. pmc Genome-wide association study identifies genetic loci associated with iron deficiency
    Christine E McLaren
    Department of Epidemiology, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 6:e17390. 2011
  9. ncbi request reprint Importance and pitfalls of molecular analysis to parasite epidemiology
    Clare C Constantine
    Western Australian Biomedical Research Institute, Division of Health Science, School of Veterinary and Biomedical Sciences, Murdoch University, South Street, Murdoch WA 6150, Australia
    Trends Parasitol 19:346-8. 2003

Detail Information

Publications9

  1. pmc SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosis
    Clare C Constantine
    The Centre for Molecular, Environmental, Genetic and Analytic MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    BMC Med Genet 9:18. 2008
    ..We report our experience of selecting tag SNPs in 35 genes involved in iron metabolism in a cohort study seeking to discover genetic modifiers of hereditary hemochromatosis...
  2. pmc HFE Cys282Tyr homozygotes with serum ferritin concentrations below 1000 microg/L are at low risk of hemochromatosis
    Katrina J Allen
    Murdoch Childrens Research Institute, Melbourne, Australia
    Hepatology 52:925-33. 2010
    ..22) and for normal SF was 6% (arthritis medicine use, 95% confidence interval = -3%, 16%; P = 0.11)...
  3. pmc HFE C282Y homozygotes are at increased risk of breast and colorectal cancer
    Nicholas J Osborne
    Gut and Liver, Murdoch Childrens Research Institute, Melbourne, Vic, Australia
    Hepatology 51:1311-8. 2010
    ..43, 2.15; P = 0.92). C282Y/H63D compound heterozygotes were not at increased risk for colorectal cancer (HR = 1.27; 95% CI = 0.80, 2.01), breast cancer (HR = 1.16; 95% CI = 0.74, 1.84), or prostate cancer (HR = 1.08; 95% CI = 0.68, 1.70)...
  4. pmc A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis
    Clare C Constantine
    Centre for MEGA Epidemiology, School of Population Health, University of Melbourne, Carlton, Victoria, Australia
    Br J Haematol 147:140-9. 2009
    ..004). This putative genetic modifier of iron overload expression accounts for 11% (95% CI 0.4%, 22.6%) of the variance in serum ferritin levels of C282Y homozygotes...
  5. doi request reprint The natural history of serum iron indices for HFE C282Y homozygosity associated with hereditary hemochromatosis
    Lyle C Gurrin
    Centre for MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    Gastroenterology 135:1945-52. 2008
    ..We characterized the development of elevated iron measures in C282Y homozygotes followed for 12 years...
  6. doi request reprint A comparison of self-reported and record-linked blood donation history in an Australian cohort
    Nadine A Bertalli
    Centre for MEGA Epidemiology, School of Population Health, The University of Melbourne, Australia
    Transfusion 51:2189-98. 2011
    ..This study aimed to retrieve electronic records from a national blood donation service and link them to self-reported history of donation to assess agreement between the two sources...
  7. doi request reprint Iron-overload-related disease in HFE hereditary hemochromatosis
    Katrina J Allen
    Murdoch Children s Research Institute, University of Melbourne, Melbourne, Australia
    N Engl J Med 358:221-30. 2008
    ..Diseases related to iron overload develop in some C282Y homozygotes, but the extent of the risk is controversial...
  8. pmc Genome-wide association study identifies genetic loci associated with iron deficiency
    Christine E McLaren
    Department of Epidemiology, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 6:e17390. 2011
    ..2p14 and iron status outcomes. These results confirm a previously-described TF polymorphism and implicate one potential new locus as a target for gene identification...
  9. ncbi request reprint Importance and pitfalls of molecular analysis to parasite epidemiology
    Clare C Constantine
    Western Australian Biomedical Research Institute, Division of Health Science, School of Veterinary and Biomedical Sciences, Murdoch University, South Street, Murdoch WA 6150, Australia
    Trends Parasitol 19:346-8. 2003
    ..All methods of analysis make assumptions which, if violated, make the results invalid. Some guidelines to avoid common pitfalls are offered here...