Don B Clewell

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint Properties of Enterococcus faecalis plasmid pAD1, a member of a widely disseminated family of pheromone-responding, conjugative, virulence elements encoding cytolysin
    Don B Clewell
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, MI 48109 1078, USA
    Plasmid 58:205-27. 2007
  2. ncbi request reprint Enterococcal plasmid transfer: sex pheromones, transfer origins, relaxases, and the Staphylococcus aureus issue
    Don B Clewell
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, MI 48109 1078, USA
    Plasmid 48:193-201. 2002
  3. ncbi request reprint Enterococcus faecalis sex pheromone plasmid pAM373: analyses of TraA and evidence for its interaction with RpoB
    Yoshiyuki Ozawa
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, MI 48109, USA
    Plasmid 54:57-69. 2005
  4. doi request reprint A "retrocidal" plasmid in Enterococcus faecalis: passage and protection
    Susan E Flannagan
    Cariology, Restorative Sciences and Endodontics, School of Dentistry, 1011 N University Avenue, Ann Arbor, MI 48109 1078, USA
    Plasmid 59:217-30. 2008
  5. ncbi request reprint Transfer origins in the conjugative Enterococcus faecalis plasmids pAD1 and pAM373: identification of the pAD1 nic site, a specific relaxase and a possible TraG-like protein
    M Victoria Francia
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, 48109, USA
    Mol Microbiol 45:375-95. 2002
  6. pmc Plasmid content of a vancomycin-resistant Enterococcus faecalis isolate from a patient also colonized by Staphylococcus aureus with a VanA phenotype
    Susan E Flannagan
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, Michigan 48109, USA
    Antimicrob Agents Chemother 47:3954-9. 2003
  7. pmc Amplification of the tetracycline resistance determinant of pAMalpha1 in Enterococcus faecalis requires a site-specific recombination event involving relaxase
    M Victoria Francia
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, Michigan 48109, USA
    J Bacteriol 184:5187-93. 2002
  8. pmc Plasmid pAMS1-encoded, bacteriocin-related "Siblicide" in Enterococcus faecalis
    Christine M Sedgley
    Department of Cariology, Restorative Sciences and Endodontics, School of Dentistry, The University of Michigan, 1011 N University Ave, Ann Arbor, MI 48109 1078, USA
    J Bacteriol 191:3183-8. 2009
  9. ncbi request reprint Identification and characterization of genes encoding sex pheromone cAM373 activity in Enterococcus faecalis and Staphylococcus aureus
    Susan E Flannagan
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, 1011 N University Ave, Ann Arbor 48109 1078, USA
    Mol Microbiol 44:803-17. 2002
  10. pmc Replication of Enterococcus faecalis pheromone-responding plasmid pAD1: location of the minimal replicon and oriV site and RepA involvement in initiation of replication
    Maria Victoria Francia
    Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI 48109 1078, USA
    J Bacteriol 186:5003-16. 2004

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Properties of Enterococcus faecalis plasmid pAD1, a member of a widely disseminated family of pheromone-responding, conjugative, virulence elements encoding cytolysin
    Don B Clewell
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, MI 48109 1078, USA
    Plasmid 58:205-27. 2007
    ..This review summarizes what is currently known about the molecular biology of pAD1, including aspects of its cytolytic, UV-resistance, replication, maintenance, and conjugative properties...
  2. ncbi request reprint Enterococcal plasmid transfer: sex pheromones, transfer origins, relaxases, and the Staphylococcus aureus issue
    Don B Clewell
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, MI 48109 1078, USA
    Plasmid 48:193-201. 2002
    ..Relevant information concerning the possible movement of vancomycin resistance from E. faecalis to S. aureus in a clinical environment is discussed...
  3. ncbi request reprint Enterococcus faecalis sex pheromone plasmid pAM373: analyses of TraA and evidence for its interaction with RpoB
    Yoshiyuki Ozawa
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, MI 48109, USA
    Plasmid 54:57-69. 2005
    ..Evidence is also presented suggesting that this regulation at t(ac) also involves an additional, possibly cis-acting, element...
  4. doi request reprint A "retrocidal" plasmid in Enterococcus faecalis: passage and protection
    Susan E Flannagan
    Cariology, Restorative Sciences and Endodontics, School of Dentistry, 1011 N University Avenue, Ann Arbor, MI 48109 1078, USA
    Plasmid 59:217-30. 2008
    ....
  5. ncbi request reprint Transfer origins in the conjugative Enterococcus faecalis plasmids pAD1 and pAM373: identification of the pAD1 nic site, a specific relaxase and a possible TraG-like protein
    M Victoria Francia
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, 48109, USA
    Mol Microbiol 45:375-95. 2002
    ..Orf53 (to be called TraW) exhibits certain structural similarities to TraG-like proteins, although there is little overall homology...
  6. pmc Plasmid content of a vancomycin-resistant Enterococcus faecalis isolate from a patient also colonized by Staphylococcus aureus with a VanA phenotype
    Susan E Flannagan
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, Michigan 48109, USA
    Antimicrob Agents Chemother 47:3954-9. 2003
    ....
  7. pmc Amplification of the tetracycline resistance determinant of pAMalpha1 in Enterococcus faecalis requires a site-specific recombination event involving relaxase
    M Victoria Francia
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, Michigan 48109, USA
    J Bacteriol 184:5187-93. 2002
    ..We also present the complete nucleotide sequence of pAMalpha1...
  8. pmc Plasmid pAMS1-encoded, bacteriocin-related "Siblicide" in Enterococcus faecalis
    Christine M Sedgley
    Department of Cariology, Restorative Sciences and Endodontics, School of Dentistry, The University of Michigan, 1011 N University Ave, Ann Arbor, MI 48109 1078, USA
    J Bacteriol 191:3183-8. 2009
    ..If the plasmid-containing host also produces gelatinase, bacteriocin cannot be detected...
  9. ncbi request reprint Identification and characterization of genes encoding sex pheromone cAM373 activity in Enterococcus faecalis and Staphylococcus aureus
    Susan E Flannagan
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, 1011 N University Ave, Ann Arbor 48109 1078, USA
    Mol Microbiol 44:803-17. 2002
    ..The particular significance of staph-cAM373 as a potential intergeneric inducer of transfer-proficient genetic elements is discussed...
  10. pmc Replication of Enterococcus faecalis pheromone-responding plasmid pAD1: location of the minimal replicon and oriV site and RepA involvement in initiation of replication
    Maria Victoria Francia
    Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI 48109 1078, USA
    J Bacteriol 186:5003-16. 2004
    ..The relationship of RepA to other known initiator proteins is also discussed...
  11. pmc Identification of the cAD1 sex pheromone precursor in Enterococcus faecalis
    Florence Y An
    Department of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, Michigan 48109, USA
    J Bacteriol 184:1880-7. 2002
    ....
  12. doi request reprint Bacteriocin-Related Siblicide in Clinical Isolates of Enterococci
    Yun Chan Hwang
    Department of Cariology, Restorative Sciences and Endodontics, School of Dentistry, The University of Michigan, Ann Arbor, MI, USA
    Probiotics Antimicrob Proteins 3:57-61. 2011
    ..faecalis and six E. faecium). Four involve inhibitory anti-listerial activities consistent with class II bacteriocins, two of which appear to be up-regulated by extracellular autoinducers. ..
  13. pmc Characterization of an active partition system for the Enterococcus faecalis pheromone-responding plasmid pAD1
    Maria Victoria Francia
    Servicio de Microbiologia, Hospital Universitario Marques de Valdecilla, Avda de Valdecilla s n, 39008 Santander, Cantabria, Spain
    J Bacteriol 189:8546-55. 2007
    ..The binding of RepC to the iteron region was shown to be modified by RepB in the presence of ATP via a possible interaction with the RepC-iteron complex. RepB did not bind to the iteron region in the absence of RepC...
  14. pmc Mutations in the aph(2")-Ic gene are responsible for increased levels of aminoglycoside resistance
    Hae Kyung Lee
    Division of Infectious Diseases, Wayne State University, Detroit, Michigan 48201, USA
    Antimicrob Agents Chemother 46:3253-6. 2002
    ..The mutated residues are located outside conserved regions of aminoglycoside phosphotransferases...
  15. pmc Possible connection between a widely disseminated conjugative gentamicin resistance (pMG1-like) plasmid and the emergence of vancomycin resistance in Enterococcus faecium
    Haruyoshi Tomita
    Department of Microbiology, Gunma University School of Medicine, Maebashi, Gunma 371 8511, Japan
    J Clin Microbiol 40:3326-33. 2002
    ..1 kb), which was originally isolated from an E. faecium clinical isolate, and transfer efficiently in broth mating...
  16. ncbi request reprint Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus
    Linda M Weigel
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Science 302:1569-71. 2003
    ..Genetic analyses suggest that the long-anticipated transfer of vancomycin resistance to a methicillin-resistant S. aureus occurred in vivo by interspecies transfer of Tn1546 from a co-isolate of Enterococcus faecalis...