P W Chiang

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint Isolation of murine SPT5 homologue: completion of the isolation and characterization of human and murine homologues of yeast chromatin structural protein complex SPT4, SPT5, and SPT6
    P W Chiang
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor 48109, USA
    Genomics 47:426-8. 1998
  2. ncbi request reprint Use of a fluorescent-PCR reaction to detect genomic sequence copy number and transcriptional abundance
    P W Chiang
    Department of Pediatrics, University of Michigan Medical School, Ann Arbor 48109 0650, USA
    Genome Res 6:1013-26. 1996
  3. ncbi request reprint Isolation, sequencing, and mapping of the human homologue of the yeast transcription factor, SPT5
    P W Chiang
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor 48109, USA
    Genomics 38:421-4. 1996
  4. pmc A fluorescent quantitative PCR approach to map gene deletions in the Drosophila genome
    P W Chiang
    Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109 0650, USA
    Genetics 153:1313-6. 1999
  5. pmc Comparison of murine Supt4h and a nearly identical expressed, processed gene: evidence of sequence conservation through gene conversion extending into the untranslated regions
    P W Chiang
    University of Michigan Medical Center, Department of Pediatrics and Department of Human Genetics, 1150 West Medical Center Drive, 3520 MSRB I, Ann Arbor, MI 48109 0650, USA
    Nucleic Acids Res 26:4960-4. 1998
  6. ncbi request reprint Detection of erbB-2 amplifications in tumors and sera from esophageal carcinoma patients
    P W Chiang
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor 48109 0650, USA
    Clin Cancer Res 5:1381-6. 1999
  7. ncbi request reprint Isolation and characterization of the human and mouse homologues (SUPT4H and Supt4h) of the yeast SPT4 gene
    P W Chiang
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor, Michigan, 48109, USA
    Genomics 34:368-75. 1996
  8. ncbi request reprint Identification and analysis of the human and murine putative chromatin structure regulator SUPT6H and Supt6h
    P W Chiang
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor 48109, USA
    Genomics 34:328-33. 1996
  9. ncbi request reprint Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region"
    W J Song
    Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
    Genomics 38:331-9. 1996
  10. doi request reprint Mutation analysis in 54 propionic acidemia patients
    J P Kraus
    Department of Pediatrics, Colorado Intellectual and Developmental Disabilities Research Center IDDRC, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA
    J Inherit Metab Dis 35:51-63. 2012

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Isolation of murine SPT5 homologue: completion of the isolation and characterization of human and murine homologues of yeast chromatin structural protein complex SPT4, SPT5, and SPT6
    P W Chiang
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor 48109, USA
    Genomics 47:426-8. 1998
  2. ncbi request reprint Use of a fluorescent-PCR reaction to detect genomic sequence copy number and transcriptional abundance
    P W Chiang
    Department of Pediatrics, University of Michigan Medical School, Ann Arbor 48109 0650, USA
    Genome Res 6:1013-26. 1996
    ..The ability to detect variations in transcript abundance enables this technique to fashion a time and tissue analysis of transcription...
  3. ncbi request reprint Isolation, sequencing, and mapping of the human homologue of the yeast transcription factor, SPT5
    P W Chiang
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor 48109, USA
    Genomics 38:421-4. 1996
    ..This argues that while there is functional similarity between SPT5 and SUPT5H, the molecules differ in the signals to which they respond...
  4. pmc A fluorescent quantitative PCR approach to map gene deletions in the Drosophila genome
    P W Chiang
    Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109 0650, USA
    Genetics 153:1313-6. 1999
    ..The rapidity and precision of this method demonstrates its applicability in Drosophila genetics, the rapid and accurate mapping of Drosophila deletion mutants...
  5. pmc Comparison of murine Supt4h and a nearly identical expressed, processed gene: evidence of sequence conservation through gene conversion extending into the untranslated regions
    P W Chiang
    University of Michigan Medical Center, Department of Pediatrics and Department of Human Genetics, 1150 West Medical Center Drive, 3520 MSRB I, Ann Arbor, MI 48109 0650, USA
    Nucleic Acids Res 26:4960-4. 1998
    ..This illustrates another potential complexity of the mammalian genome, i.e. the use of a processed gene under the control of a different promoter region than the spliced gene...
  6. ncbi request reprint Detection of erbB-2 amplifications in tumors and sera from esophageal carcinoma patients
    P W Chiang
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor 48109 0650, USA
    Clin Cancer Res 5:1381-6. 1999
    ..The capability of TaqMan PCR to detect abnormalities in serum of esophageal cancer patients creates an opportunity to diagnose esophageal cancer and to monitor the outcome of treatment with a blood test...
  7. ncbi request reprint Isolation and characterization of the human and mouse homologues (SUPT4H and Supt4h) of the yeast SPT4 gene
    P W Chiang
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor, Michigan, 48109, USA
    Genomics 34:368-75. 1996
    ..g., such as most histones), in all fetal and adult tissues that we examined...
  8. ncbi request reprint Identification and analysis of the human and murine putative chromatin structure regulator SUPT6H and Supt6h
    P W Chiang
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor 48109, USA
    Genomics 34:328-33. 1996
    ..These data indicate that SUPT6H and Supt6h are functionally analogous to SPT6 and emb-5 and may therefore regulate transcription through establishment or maintenance of chromatin structure...
  9. ncbi request reprint Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region"
    W J Song
    Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
    Genomics 38:331-9. 1996
    ....
  10. doi request reprint Mutation analysis in 54 propionic acidemia patients
    J P Kraus
    Department of Pediatrics, Colorado Intellectual and Developmental Disabilities Research Center IDDRC, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA
    J Inherit Metab Dis 35:51-63. 2012
    ..Numerous new intronic polymorphisms in both PCC genes were identified. This study adds a considerable amount of new molecular data to the studies of this disease...
  11. ncbi request reprint Matroshka and ectopic polymorphisms: Two new classes of DNA sequence variation identified at the Van der Woude syndrome locus on 1q32-q41
    Y Watanabe
    Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA
    Hum Mutat 18:422-34. 2001
    ..These two novel classes of DNA sequence polymorphisms have the potential to confound genetic and DNA sequence analysis and may also contribute to variation in disease phenotypes...
  12. ncbi request reprint Linkage mapping of murine homolog of the yeast SPT6 gene to MMU11B1
    P W Chiang
    Department of Pediatrics, University of Michigan Medical Center, Ann Arbor 48109 0650, USA
    Mamm Genome 7:459-60. 1996
  13. ncbi request reprint The 5'-untranslated region of the FMR1 message facilitates translation by internal ribosome entry
    P W Chiang
    Program in Human Genetics, University of Colorado School of Medicine, Denver, Colorado 80262, USA
    J Biol Chem 276:37916-21. 2001
    ..The role of the FMR1 IRES element is not known at present; however, by analogy to other IRES-containing mRNAs expressed in neurons, the FMR1 IRES element may help to promote translation in dendrites...